Published in Biochem Biophys Res Commun on January 28, 2012
Redox regulation of SIRT1 in inflammation and cellular senescence. Free Radic Biol Med (2013) 1.17
Nutrient-sensing pathways and metabolic regulation in stem cells. J Cell Biol (2013) 1.08
Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance. J Exp Med (2013) 1.06
Epigenetic Control of Stem Cell Potential during Homeostasis, Aging, and Disease. Cell Stem Cell (2015) 0.94
Connecting Mitochondria, Metabolism, and Stem Cell Fate. Stem Cells Dev (2015) 0.91
SIRT1 is a Highly Networked Protein That Mediates the Adaptation to Chronic Physiological Stress. Genes Cancer (2013) 0.89
Epigenetic control of adult stem cell function. Nat Rev Mol Cell Biol (2016) 0.88
Adult Stem Cells and Diseases of Aging. J Clin Med (2014) 0.88
Role of SIRT1 in the growth and regulation of normal hematopoietic and leukemia stem cells. Curr Opin Hematol (2015) 0.87
Roles of SIRT1 in leukemogenesis. Curr Opin Hematol (2013) 0.83
Stem cell transplantation upregulates Sirt1 and antioxidant expression, ameliorating fatty liver in type 2 diabetic mice. Int J Biol Sci (2015) 0.81
Cellular Senescence as the Causal Nexus of Aging. Front Genet (2016) 0.80
Role of sirtuins in stem cell differentiation. Genes Cancer (2013) 0.79
Resveratrol increases the bone marrow hematopoietic stem and progenitor cell capacity. Am J Hematol (2014) 0.79
Resveratrol Protects against Sepsis-Associated Encephalopathy and Inhibits the NLRP3/IL-1β Axis in Microglia. Mediators Inflamm (2016) 0.77
Sirtuins, tissue maintenance, and tumorigenesis. Genes Cancer (2013) 0.76
Comparison of Different Cytokine Conditions Reveals Resveratrol as a New Molecule for Ex Vivo Cultivation of Cord Blood-Derived Hematopoietic Stem Cells. Stem Cells Transl Med (2015) 0.75
MEK1 signaling promotes self-renewal and tumorigenicity of liver cancer stem cells via maintaining SIRT1 protein stabilization. Oncotarget (2016) 0.75
SIRT1 is a critical regulator of K562 cell growth, survival, and differentiation. Exp Cell Res (2016) 0.75
Sirtuins at the crossroads of stemness, aging, and cancer. Aging Cell (2017) 0.75
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature (2004) 10.32
S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex. Nature (2003) 6.43
Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. Dev Cell (2008) 5.51
Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease. Blood (2005) 4.29
SirT1 regulates energy metabolism and response to caloric restriction in mice. PLoS One (2008) 3.66
AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol. Diabetes (2009) 3.39
SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons. Cell Metab (2008) 3.35
A local mechanism mediates NAD-dependent protection of axon degeneration. J Cell Biol (2005) 2.64
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans. Proc Natl Acad Sci U S A (2013) 2.47
Retracted Generation of cell polarity in plants links endocytosis, auxin distribution and cell fate decisions. Nature (2008) 2.42
SIRT1 regulates HIV transcription via Tat deacetylation. PLoS Biol (2005) 2.24
E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination. Mol Cell (2002) 2.20
Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damage. Cell Cycle (2006) 2.17
Cytokinin modulates endocytic trafficking of PIN1 auxin efflux carrier to control plant organogenesis. Dev Cell (2011) 2.12
Sirt1-deficient mice exhibit an altered cartilage phenotype. Joint Bone Spine (2013) 2.06
The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice. J Clin Invest (2009) 2.02
Roles for c-Myc in self-renewal of hematopoietic stem cells. J Biol Chem (2004) 1.95
A new method for rapid visualization of defects in leaf cuticle reveals five intrinsic patterns of surface defects in Arabidopsis. Plant J (2004) 1.94
Genetic variants in C5 and poor response to eculizumab. N Engl J Med (2014) 1.91
Adiponectin acts as an endogenous antithrombotic factor. Arterioscler Thromb Vasc Biol (2005) 1.88
Molecular basis of clonal expansion of hematopoiesis in 2 patients with paroxysmal nocturnal hemoglobinuria (PNH). Blood (2006) 1.86
SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice. J Clin Invest (2012) 1.82
Top1- and Top2-mediated topological transitions at replication forks ensure fork progression and stability and prevent DNA damage checkpoint activation. Genes Dev (2007) 1.75
Ischemic postconditioning with lactate-enriched blood in patients with acute myocardial infarction. Cardiology (2013) 1.74
SIRT1 is essential for normal cognitive function and synaptic plasticity. J Neurosci (2010) 1.71
Suppressor of cytokine signalling-1 gene silencing in acute myeloid leukaemia and human haematopoietic cell lines. Br J Haematol (2004) 1.70
Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations. Blood (2002) 1.68
sirt1-null mice develop an autoimmune-like condition. Exp Cell Res (2008) 1.67
Clinical course and flow cytometric analysis of paroxysmal nocturnal hemoglobinuria in the United States and Japan. Medicine (Baltimore) (2004) 1.67
E2F1 and c-Myc in cell growth and death. Cell Cycle (2003) 1.64
The endothelial antigen ESAM marks primitive hematopoietic progenitors throughout life in mice. Blood (2008) 1.63
The Satb1 protein directs hematopoietic stem cell differentiation toward lymphoid lineages. Immunity (2013) 1.58
Csm3, Tof1, and Mrc1 form a heterotrimeric mediator complex that associates with DNA replication forks. J Biol Chem (2009) 1.54
Clathrin mediates endocytosis and polar distribution of PIN auxin transporters in Arabidopsis. Plant Cell (2011) 1.53
Successful in vivo propagation of factor IX-producing hepatocytes in mice: potential for cell-based therapy in haemophilia B. Thromb Haemost (2008) 1.49
Expansion of the cell plate in plant cytokinesis requires a kinesin-like protein/MAPKKK complex. Cell (2002) 1.48
Three- and four-dimensional HDlive rendering images of normal and abnormal fetuses: pictorial essay. Arch Gynecol Obstet (2012) 1.47
Exploring binary-neutron-star-merger scenario of short-gamma-ray bursts by gravitational-wave observation. Phys Rev Lett (2010) 1.45
Recycling, clustering, and endocytosis jointly maintain PIN auxin carrier polarity at the plasma membrane. Mol Syst Biol (2011) 1.44
Important parameters in the detection of left main trunk disease using stress myocardial perfusion imaging. J Cardiol (2008) 1.42
Retrospective nationwide survey of Japanese patients with transfusion-dependent MDS and aplastic anemia highlights the negative impact of iron overload on morbidity/mortality. Eur J Haematol (2007) 1.41
Acquired activated protein C resistance is associated with the co-existence of anti-prothrombin antibodies and lupus anticoagulant activity in patients with systemic lupus erythematosus. Br J Haematol (2002) 1.40
SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis. Eur Heart J (2010) 1.40
Postischemic myocardial stunning is superior to transient ischemic dilation for detecting multivessel coronary artery disease. Circ J (2011) 1.38
Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation. Cell Host Microbe (2008) 1.35
Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: implication in pathogenesis of COPD. Arch Biochem Biophys (2010) 1.34
SirT1 fails to affect p53-mediated biological functions. Aging Cell (2006) 1.33
The ACR4 receptor-like kinase is required for surface formation of epidermis-related tissues in Arabidopsis thaliana. Plant J (2004) 1.30
The scaffolding adapter Gab2, via Shp-2, regulates kit-evoked mast cell proliferation by activating the Rac/JNK pathway. J Biol Chem (2006) 1.27
Transcriptional control of T-cell development. Int Immunol (2011) 1.24
Ex vivo gene therapy for hemophilia A that enhances safe delivery and sustained in vivo factor VIII expression from lentivirally engineered endothelial progenitors. Stem Cells (2007) 1.22
In situ removal of carbon contamination from optics in a vacuum ultraviolet and soft X-ray undulator beamline using oxygen activated by zeroth-order synchrotron radiation. J Synchrotron Radiat (2012) 1.20
Sirt1 interacts with transducin-like enhancer of split-1 to inhibit nuclear factor kappaB-mediated transcription. Biochem J (2007) 1.19
Paracrine regulation of fat cell formation in bone marrow cultures via adiponectin and prostaglandins. J Clin Invest (2002) 1.19
Identification of a cytokine-induced antiapoptotic molecule anamorsin essential for definitive hematopoiesis. J Exp Med (2004) 1.17
Diagnostic value of left ventricular function after adenosine triphosphate loading and at rest in the detection of multi-vessel coronary artery disease using myocardial perfusion imaging. J Nucl Cardiol (2009) 1.17
Notch signals inhibit the development of erythroid/megakaryocytic cells by suppressing GATA-1 activity through the induction of HES1. J Biol Chem (2004) 1.15
GATA-2/estrogen receptor chimera regulates cytokine-dependent growth of hematopoietic cells through accumulation of p21(WAF1) and p27(Kip1) proteins. Blood (2002) 1.15
The presence of anti-phosphatidylserine/prothrombin antibodies as risk factor for both arterial and venous thrombosis in patients with systemic lupus erythematosus. Haematologica (2006) 1.11
Soluble frizzled-related protein 1 is estrogen inducible in bone marrow stromal cells and suppresses the earliest events in lymphopoiesis. J Immunol (2008) 1.11
Diagnostic value of left ventricular function after stress and at rest in the detection of multivessel coronary artery disease as assessed by electrocardiogram-gated SPECT. J Nucl Cardiol (2007) 1.11
Adiponectin, a fat cell product, influences the earliest lymphocyte precursors in bone marrow cultures by activation of the cyclooxygenase-prostaglandin pathway in stromal cells. J Immunol (2003) 1.10
Silent information regulator 1 protects the brain against cerebral ischemic damage. Stroke (2013) 1.09
Stimulation of 3T3-L1 adipogenesis by signal transducer and activator of transcription 5. Mol Endocrinol (2002) 1.09
SIRT1 but not its increased expression is essential for lifespan extension in caloric-restricted mice. Aging Cell (2013) 1.06
Negative regulation of platelet function by a secreted cell repulsive protein, semaphorin 3A. Blood (2005) 1.05
Brain regions involved in fatigue sensation: reduced acetylcarnitine uptake into the brain. Neuroimage (2002) 1.05
Sirtuin 1 in immune regulation and autoimmunity. Immunol Cell Biol (2011) 1.05
A role for neuronal cAMP responsive-element binding (CREB)-1 in brain responses to calorie restriction. Proc Natl Acad Sci U S A (2011) 1.05
Modulation of TLR4 signaling by a novel adaptor protein signal-transducing adaptor protein-2 in macrophages. J Immunol (2006) 1.05
BEX5/RabA1b regulates trans-Golgi network-to-plasma membrane protein trafficking in Arabidopsis. Plant Cell (2012) 1.05
Functional cooperation among Ras, STAT5, and phosphatidylinositol 3-kinase is required for full oncogenic activities of BCR/ABL in K562 cells. J Biol Chem (2002) 1.04