Published in Blood on October 04, 2005
Systems approaches to preventing transplanted cell death in cardiac repair. J Mol Cell Cardiol (2008) 2.60
Foxo3 is required for the regulation of oxidative stress in erythropoiesis. J Clin Invest (2007) 2.39
Role of erythropoietin in the brain. Crit Rev Oncol Hematol (2007) 1.50
Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies. Nucleic Acids Res (2012) 1.38
MicroRNA-486 regulates normal erythropoiesis and enhances growth and modulates drug response in CML progenitors. Blood (2014) 1.32
Down-regulation of Myc is essential for terminal erythroid maturation. J Biol Chem (2010) 1.30
WNT1-inducible signaling pathway protein-1 activates diverse cell survival pathways and blocks doxorubicin-induced cardiomyocyte death. Cell Signal (2010) 1.28
AKT induces erythroid-cell maturation of JAK2-deficient fetal liver progenitor cells and is required for Epo regulation of erythroid-cell differentiation. Blood (2005) 1.25
ROS-mediated amplification of AKT/mTOR signalling pathway leads to myeloproliferative syndrome in Foxo3(-/-) mice. EMBO J (2010) 1.24
A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia. Blood (2007) 1.15
SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis. J Exp Med (2010) 1.10
Pro-inflammatory cytokine-mediated anemia: regarding molecular mechanisms of erythropoiesis. Mediators Inflamm (2010) 1.10
Controlling hematopoiesis through sumoylation-dependent regulation of a GATA factor. Mol Cell (2009) 1.09
mTOR inhibitors alone and in combination with JAK2 inhibitors effectively inhibit cells of myeloproliferative neoplasms. PLoS One (2013) 1.08
Ligand-induced EpoR internalization is mediated by JAK2 and p85 and is impaired by mutations responsible for primary familial and congenital polycythemia. Blood (2009) 1.07
Common themes emerge in the transcriptional control of T helper and developmental cell fate decisions regulated by the T-box, GATA and ROR families. Immunology (2009) 0.97
Positive receptor feedback during lineage commitment can generate ultrasensitivity to ligand and confer robustness to a bistable switch. Biophys J (2008) 0.97
Erythropoietin, a novel versatile player regulating energy metabolism beyond the erythroid system. Int J Biol Sci (2014) 0.96
Mammalian erythroblast enucleation requires PI3K-dependent cell polarization. J Cell Sci (2012) 0.95
NF-E2 overexpression delays erythroid maturation and increases erythrocyte production. Br J Haematol (2009) 0.95
Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110α. J Clin Invest (2014) 0.94
Emerging EPO and EPO receptor regulators and signal transducers. Blood (2015) 0.93
Endogenous erythropoietin signaling facilitates skeletal muscle repair and recovery following pharmacologically induced damage. FASEB J (2012) 0.93
Phosphorylation of Gata1 at serine residues 72, 142, and 310 is not essential for hematopoiesis in vivo. Blood (2006) 0.92
Enhancement of ventricular-subventricular zone-derived neurogenesis and oligodendrogenesis by erythropoietin and its derivatives. Front Cell Neurosci (2013) 0.91
Transcriptional ontogeny of the developing liver. BMC Genomics (2012) 0.91
Erythropoietin action in stress response, tissue maintenance and metabolism. Int J Mol Sci (2014) 0.91
The GATA factor revolution in hematology. Blood (2017) 0.90
Erythropoietin signaling promotes transplanted progenitor cell survival. FASEB J (2009) 0.90
Transcriptional mechanisms underlying hemoglobin synthesis. Cold Spring Harb Perspect Med (2013) 0.90
Integrating extrinsic and intrinsic cues into a minimal model of lineage commitment for hematopoietic progenitors. PLoS Comput Biol (2009) 0.89
The erythropoietin receptor: molecular structure and hematopoietic signaling pathways. J Investig Med (2011) 0.88
Sumoylation regulates interaction of FOG1 with C-terminal-binding protein (CTBP). J Biol Chem (2010) 0.87
GSK3 regulates the expressions of human and mouse c-Myb via different mechanisms. Cell Div (2010) 0.85
Phosphoinositide 3-kinase signalling regulates early development and developmental haemopoiesis. J Cell Sci (2007) 0.85
FOXO3-mTOR metabolic cooperation in the regulation of erythroid cell maturation and homeostasis. Am J Hematol (2014) 0.85
ARR19 (androgen receptor corepressor of 19 kDa), an antisteroidogenic factor, is regulated by GATA-1 in testicular Leydig cells. J Biol Chem (2009) 0.83
Advances in understanding the pathogenesis of primary familial and congenital polycythaemia. Br J Haematol (2010) 0.83
Mechanism governing heme synthesis reveals a GATA factor/heme circuit that controls differentiation. EMBO Rep (2015) 0.82
Protein kinase D-HDAC5 signaling regulates erythropoiesis and contributes to erythropoietin cross-talk with GATA1. Blood (2012) 0.81
A Systems Approach Identifies Essential FOXO3 Functions at Key Steps of Terminal Erythropoiesis. PLoS Genet (2015) 0.81
Erythropoietin improves neurobehavior by reducing dopaminergic neuron loss in a 6‑hydroxydopamine‑induced rat model. Int J Mol Med (2014) 0.81
Resveratrol increases the bone marrow hematopoietic stem and progenitor cell capacity. Am J Hematol (2014) 0.79
Erythropoiesis from human embryonic stem cells through erythropoietin-independent AKT signaling. Stem Cells (2014) 0.79
Constitutive phosphorylation of GATA-1 at serine²⁶ attenuates the colony-forming activity of erythrocyte-committed progenitors. PLoS One (2013) 0.78
Erythropoietin and IGF-1 signaling synchronize cell proliferation and maturation during erythropoiesis. Genes Dev (2015) 0.77
Akt1-mediated Gata3 phosphorylation controls the repression of IFNγ in memory-type Th2 cells. Nat Commun (2016) 0.76
Chronic restraint stress upregulates erythropoiesis through glucocorticoid stimulation. PLoS One (2013) 0.76
α-1,6-Fucosyltransferase (FUT8) inhibits hemoglobin production during differentiation of murine and K562 human erythroleukemia cells. J Biol Chem (2013) 0.76
The role of glucocorticoid receptor (GR) polymorphisms in human erythropoiesis. Am J Blood Res (2014) 0.75
Nutrition regulation of male accessory gland growth and maturation in Tribolium castaneum. Sci Rep (2015) 0.75
Effect of alpha lipoic acid on retinal ganglion cell survival in an optic nerve crush model. Mol Vis (2016) 0.75
Epo reprograms the epigenome of erythroid cells. Exp Hematol (2017) 0.75
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell (1999) 32.32
A gain-of-function mutation of JAK2 in myeloproliferative disorders. N Engl J Med (2005) 21.48
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet (2005) 18.59
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature (2005) 18.43
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell (2005) 17.41
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta). Science (2001) 11.22
Role of translocation in the activation and function of protein kinase B. J Biol Chem (1997) 7.29
Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice. J Biol Chem (2001) 7.10
Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase. FEBS Lett (1996) 6.16
Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene. Genes Dev (2001) 6.15
Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2. Genes Dev (2003) 5.91
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a). Mol Cell Biol (2001) 5.78
Identification of an acquired JAK2 mutation in polycythemia vera. J Biol Chem (2005) 5.58
Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells. Genes Dev (1994) 5.22
Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1. Proc Natl Acad Sci U S A (1996) 5.20
Transcriptional regulation of erythropoiesis: an affair involving multiple partners. Oncogene (2002) 4.80
Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell (1995) 4.73
Regulation of activity of the transcription factor GATA-1 by acetylation. Nature (1998) 4.68
Advances in protein kinase B signalling: AKTion on multiple fronts. Trends Biochem Sci (2004) 4.40
Global regulation of erythroid gene expression by transcription factor GATA-1. Blood (2004) 4.22
Erythroid-cell-specific properties of transcription factor GATA-1 revealed by phenotypic rescue of a gene-targeted cell line. Mol Cell Biol (1997) 4.12
CREB is a regulatory target for the protein kinase Akt/PKB. J Biol Chem (1998) 4.12
Role for Akt3/protein kinase Bgamma in attainment of normal brain size. Mol Cell Biol (2005) 4.00
Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance. J Biol Chem (2001) 3.86
NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1. Science (1993) 3.74
Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway. EMBO J (1999) 3.41
CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation. Proc Natl Acad Sci U S A (1998) 3.22
Polycythemia vera: myths, mechanisms, and management. Blood (2002) 3.01
Phosphorylation of p53 serine 15 increases interaction with CBP. J Biol Chem (1998) 2.97
Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis. Proc Natl Acad Sci U S A (1995) 2.78
Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta. J Biol Chem (1997) 2.70
GATA-1 and erythropoietin cooperate to promote erythroid cell survival by regulating bcl-xL expression. Blood (1999) 2.62
GATA-1-mediated proliferation arrest during erythroid maturation. Mol Cell Biol (2003) 2.52
CREB-Binding protein acetylates hematopoietic transcription factor GATA-1 at functionally important sites. Mol Cell Biol (1999) 2.26
Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis. Genes Dev (1996) 2.18
Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival. Blood (2005) 2.09
Circulating erythroid progenitors in polycythemia vera are hypersensitive to insulin-like growth factor-1 in vitro: studies in an improved serum-free medium. Blood (1994) 1.84
Cytokines and BCR-ABL mediate suppression of TRAIL-induced apoptosis through inhibition of forkhead FOXO3a transcription factor. Proc Natl Acad Sci U S A (2003) 1.80
Dynamics of GATA transcription factor expression during erythroid differentiation. Blood (1993) 1.69
Phosphorylation of the erythroid transcription factor GATA-1. J Biol Chem (1994) 1.65
Identification of a novel pathway important for proliferation and differentiation of primary erythroid progenitors. Proc Natl Acad Sci U S A (1997) 1.57
Accentuated response to phenylhydrazine and erythropoietin in mice genetically impaired for their GATA-1 expression (GATA-1(low) mice). Blood (2001) 1.51
Akt regulates basic helix-loop-helix transcription factor-coactivator complex formation and activity during neuronal differentiation. Mol Cell Biol (2003) 1.49
Multiple signaling pathways are involved in erythropoietin-independent differentiation of erythroid progenitors in polycythemia vera. Exp Hematol (2004) 1.46
An intrinsic but cell-nonautonomous defect in GATA-1-overexpressing mouse erythroid cells. Nature (2000) 1.45
Critical role for PI 3-kinase in the control of erythropoietin-induced erythroid progenitor proliferation. Blood (2002) 1.43
Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor. Proc Natl Acad Sci U S A (1996) 1.39
Identification of CISK, a new member of the SGK kinase family that promotes IL-3-dependent survival. Curr Biol (2000) 1.36
Recent insights into the mechanisms of myeloid leukemogenesis in Down syndrome. Blood (2003) 1.34
Cytokine manipulation of primitive human hematopoietic cell self-renewal. Proc Natl Acad Sci U S A (1997) 1.29
AKT induces erythroid-cell maturation of JAK2-deficient fetal liver progenitor cells and is required for Epo regulation of erythroid-cell differentiation. Blood (2005) 1.25
DNA damage-induced cell-cycle arrest of hematopoietic cells is overridden by activation of the PI-3 kinase/Akt signaling pathway. Blood (2001) 1.17
Phosphatidylinositol 3-kinase is involved in the protection of primary cultured human erythroid precursor cells from apoptosis. Blood (1999) 1.14
Phosphorylation of GATA-1 increases its DNA-binding affinity and is correlated with induction of human K562 erythroleukaemia cells. Nucleic Acids Res (1999) 1.12
Increased erythropoiesis in polycythemia vera is associated with increased erythroid progenitor proliferation and increased phosphorylation of Akt/PKB. Exp Hematol (2005) 1.09
Involvement of mitogen-activated protein kinase in the cytokine-regulated phosphorylation of transcription factor GATA-1. Hematol J (2004) 1.00
Erythropoiesis in the absence of janus-kinase 2: BCR-ABL induces red cell formation in JAK2(-/-) hematopoietic progenitors. Blood (2001) 0.98
Activation of the Akt/FKHRL1 pathway mediates the antiapoptotic effects of erythropoietin in primary human erythroid progenitors. Biochem Biophys Res Commun (2000) 0.98
Functional p85alpha gene is required for normal murine fetal erythropoiesis. Blood (2003) 0.94
Receptor specificity in the self-renewal and differentiation of primary multipotential hemopoietic cells. Blood (2001) 0.94
The prolactin receptor rescues EpoR-/- erythroid progenitors and replaces EpoR in a synergistic interaction with c-kit. Blood (1998) 0.93
BCR-ABL and v-SRC tyrosine kinase oncoproteins support normal erythroid development in erythropoietin receptor-deficient progenitor cells. Proc Natl Acad Sci U S A (1999) 0.93
Regulation and function of transcription factor GATA-1 during red blood cell differentiation. Development (1996) 0.88
Insulin-like growth factor binding protein-1 is elevated in patients with polycythemia vera and stimulates erythroid burst formation in vitro. Blood (1997) 0.78
Erythropoietin-induced transcription at the murine beta maj-globin promoter. A central role for GATA-1. J Biol Chem (1995) 0.77
MicroRNAs modulate hematopoietic lineage differentiation. Science (2003) 30.05
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature (2008) 18.20
Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Res (2003) 14.79
Regulation of progenitor cell proliferation and granulocyte function by microRNA-223. Nature (2008) 8.69
JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis. N Engl J Med (2007) 8.18
Myogenic factors that regulate expression of muscle-specific microRNAs. Proc Natl Acad Sci U S A (2006) 6.19
Recurrent BRAF mutations in Langerhans cell histiocytosis. Blood (2010) 4.96
Role of Ras signaling in erythroid differentiation of mouse fetal liver cells: functional analysis by a flow cytometry-based novel culture system. Blood (2003) 4.91
MicroRNA-125b is a novel negative regulator of p53. Genes Dev (2009) 4.43
Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc Natl Acad Sci U S A (2002) 4.40
miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely. Proc Natl Acad Sci U S A (2007) 4.15
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes (2010) 4.07
Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA). Nat Genet (2008) 4.02
Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease. Blood (2002) 3.93
T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin. Proc Natl Acad Sci U S A (2004) 3.90
Immortalization and transformation of primary human airway epithelial cells by gene transfer. Oncogene (2002) 3.80
Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Nat Genet (2005) 3.28
A mouse model of juvenile hemochromatosis. J Clin Invest (2005) 3.25
Angiopoietin-like proteins stimulate ex vivo expansion of hematopoietic stem cells. Nat Med (2006) 3.09
Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity. Cancer Res (2007) 3.04
MicroRNAs induced during adipogenesis that accelerate fat cell development are downregulated in obesity. Diabetes (2009) 3.02
Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/SCID transplantation. Blood (2008) 2.79
MicroRNAs as regulators of mammalian hematopoiesis. Semin Immunol (2005) 2.62
Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5. Cancer Cell (2002) 2.51
Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2. Nat Cell Biol (2008) 2.50
Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure. Circ Res (2009) 2.44
Insulin-like growth factor 2 expressed in a novel fetal liver cell population is a growth factor for hematopoietic stem cells. Blood (2003) 2.42
From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications. Blood (2011) 2.42
Foxo3 is required for the regulation of oxidative stress in erythropoiesis. J Clin Invest (2007) 2.39
The Steap proteins are metalloreductases. Blood (2006) 2.37
Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia. Nat Genet (2009) 2.37
Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors. Development (2010) 2.31
ACRP30, a new hormone controlling fat and glucose metabolism. Eur J Pharmacol (2002) 2.31
Role of disulfide bonds in Acrp30/adiponectin structure and signaling specificity. Different oligomers activate different signal transduction pathways. J Biol Chem (2003) 2.29
MicroRNA miR-125b causes leukemia. Proc Natl Acad Sci U S A (2010) 2.29
Oligomerization state-dependent activation of NF-kappa B signaling pathway by adipocyte complement-related protein of 30 kDa (Acrp30). J Biol Chem (2002) 2.20
Mir193b-365 is essential for brown fat differentiation. Nat Cell Biol (2011) 2.20
Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis. Blood (2010) 2.20
Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways. Blood (2005) 2.17
Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle. J Clin Invest (2004) 2.12
Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation. Blood (2013) 2.12
Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells. Proc Natl Acad Sci U S A (2002) 2.08
MicroRNA-125b promotes neuronal differentiation in human cells by repressing multiple targets. Mol Cell Biol (2009) 2.08
Lymphomas of the breast: primary and secondary involvement. Cancer (2002) 2.06
Long noncoding RNA-mediated anti-apoptotic activity in murine erythroid terminal differentiation. Genes Dev (2011) 2.06
A family of Acrp30/adiponectin structural and functional paralogs. Proc Natl Acad Sci U S A (2004) 2.06
Murine hematopoietic stem cells change their surface phenotype during ex vivo expansion. Blood (2005) 2.05
Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis. J Exp Med (2004) 1.98
Insulin resistance in adipose tissue: direct and indirect effects of tumor necrosis factor-alpha. Cytokine Growth Factor Rev (2003) 1.96
Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells. J Biol Chem (2008) 1.95
Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins. Nature (2008) 1.95
An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe(-/-) mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia. Blood (2012) 1.94
Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal. Proc Natl Acad Sci U S A (2006) 1.92
Long noncoding RNAs regulate adipogenesis. Proc Natl Acad Sci U S A (2013) 1.90
Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia. Nat Med (2013) 1.89
Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking. Nature (2003) 1.88
Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia. Blood (2010) 1.86
T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation. Cancer Cell (2010) 1.85
Regulation of mammalian cell differentiation by long non-coding RNAs. EMBO Rep (2012) 1.82
Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators. Am J Physiol Endocrinol Metab (2002) 1.82
miR-451 protects against erythroid oxidant stress by repressing 14-3-3zeta. Genes Dev (2010) 1.80
Cytokines and BCR-ABL mediate suppression of TRAIL-induced apoptosis through inhibition of forkhead FOXO3a transcription factor. Proc Natl Acad Sci U S A (2003) 1.80
Tankyrase-2 oligomerizes with tankyrase-1 and binds to both TRF1 (telomere-repeat-binding factor 1) and IRAP (insulin-responsive aminopeptidase). Biochem J (2002) 1.79
Identification and characterization of CTRP9, a novel secreted glycoprotein, from adipose tissue that reduces serum glucose in mice and forms heterotrimers with adiponectin. FASEB J (2008) 1.77
FOXO1 is an essential regulator of pluripotency in human embryonic stem cells. Nat Cell Biol (2011) 1.70
Troglitazone antagonizes tumor necrosis factor-alpha-induced reprogramming of adipocyte gene expression by inhibiting the transcriptional regulatory functions of NF-kappaB. J Biol Chem (2003) 1.67
Insulin causes fatty acid transport protein translocation and enhanced fatty acid uptake in adipocytes. Dev Cell (2002) 1.67
HIF1alpha synergizes with glucocorticoids to promote BFU-E progenitor self-renewal. Blood (2010) 1.63
A proteomic approach for identification of secreted proteins during the differentiation of 3T3-L1 preadipocytes to adipocytes. Mol Cell Proteomics (2002) 1.61
Context-specific effects of fibulin-5 (DANCE/EVEC) on cell proliferation, motility, and invasion. Fibulin-5 is induced by transforming growth factor-beta and affects protein kinase cascades. J Biol Chem (2002) 1.58
Docosahexaenoic acid, fatty acid-interacting proteins, and neuronal function: breastmilk and fish are good for you. Annu Rev Cell Dev Biol (2005) 1.55
Conserved regulation of p53 network dosage by microRNA-125b occurs through evolving miRNA-target gene pairs. PLoS Genet (2011) 1.55
Dimerization by a cytokine receptor is necessary for constitutive activation of JAK2V617F. J Biol Chem (2007) 1.55
MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13. Proc Natl Acad Sci U S A (2011) 1.54
Cytokines regulating hematopoietic stem cell function. Curr Opin Hematol (2008) 1.54
Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice. Blood (2011) 1.49
The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis. Hum Mol Genet (2006) 1.47
Standard isolation of primary adipose cells from mouse epididymal fat pads induces inflammatory mediators and down-regulates adipocyte genes. J Biol Chem (2003) 1.45
Iron-responsive degradation of iron-regulatory protein 1 does not require the Fe-S cluster. EMBO J (2006) 1.43
Systematic molecular genetic analysis of congenital sideroblastic anemia: evidence for genetic heterogeneity and identification of novel mutations. Pediatr Blood Cancer (2010) 1.43
Gene induction and repression during terminal erythropoiesis are mediated by distinct epigenetic changes. Blood (2011) 1.43
The endoglin(positive) sca-1(positive) rhodamine(low) phenotype defines a near-homogeneous population of long-term repopulating hematopoietic stem cells. Immunity (2003) 1.42
Transferrin is a major determinant of hepcidin expression in hypotransferrinemic mice. Blood (2010) 1.41
X-linked gray platelet syndrome due to a GATA1 Arg216Gln mutation. Blood (2007) 1.38
Oxidative stress regulation of stem and progenitor cells. Antioxid Redox Signal (2009) 1.38
nm1054: a spontaneous, recessive, hypochromic, microcytic anemia mutation in the mouse. Blood (2005) 1.38
Active conformation of the erythropoietin receptor: random and cysteine-scanning mutagenesis of the extracellular juxtamembrane and transmembrane domains. J Biol Chem (2006) 1.37
Insulin-like growth factor-binding protein 2 secreted by a tumorigenic cell line supports ex vivo expansion of mouse hematopoietic stem cells. Stem Cells (2008) 1.36
Alpha4beta1 integrin and erythropoietin mediate temporally distinct steps in erythropoiesis: integrins in red cell development. J Cell Biol (2007) 1.35
Distinct roles for miR-1 and miR-133a in the proliferation and differentiation of rhabdomyosarcoma cells. FASEB J (2010) 1.32
Mesenchymal stem cells secreting angiopoietin-like-5 support efficient expansion of human hematopoietic stem cells without compromising their repopulating potential. Stem Cells Dev (2011) 1.32
Down-regulation of Myc is essential for terminal erythroid maturation. J Biol Chem (2010) 1.30
An extended bipartite nuclear localization signal in Smad4 is required for its nuclear import and transcriptional activity. Oncogene (2003) 1.29
Profiling gene transcription in vivo reveals adipose tissue as an immediate target of tumor necrosis factor-alpha: implications for insulin resistance. Diabetes (2002) 1.29
Cellular trafficking and degradation of erythropoietin and novel erythropoiesis stimulating protein (NESP). J Biol Chem (2005) 1.29