Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition.

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Published in Genome Res on September 12, 2014

Authors

Scott A Lujan1, Anders R Clausen1, Alan B Clark1, Heather K MacAlpine2, David M MacAlpine2, Ewa P Malc3, Piotr A Mieczkowski3, Adam B Burkholder4, David C Fargo4, Dmitry A Gordenin5, Thomas A Kunkel6

Author Affiliations

1: Laboratory of Molecular Genetics, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA; Laboratory of Structural Biology, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA;
2: Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA;
3: Department of Genetics, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599, USA;
4: Integrative Bioinformatics, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA.
5: Laboratory of Molecular Genetics, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA;
6: Laboratory of Molecular Genetics, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA; Laboratory of Structural Biology, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA; kunkel@niehs.nih.gov.

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