Published in Nucleic Acids Res on August 26, 2006
The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases. Cell Res (2008) 3.15
Dividing the workload at a eukaryotic replication fork. Trends Cell Biol (2008) 2.94
Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes. Nat Chem Biol (2011) 2.20
Flexibility of eukaryotic Okazaki fragment maturation through regulated strand displacement synthesis. J Biol Chem (2008) 1.73
Inefficient proofreading and biased error rates during inaccurate DNA synthesis by a mutant derivative of Saccharomyces cerevisiae DNA polymerase delta. J Biol Chem (2006) 1.70
The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins. Nucleic Acids Res (2006) 1.57
PCNA is required for initiation of recombination-associated DNA synthesis by DNA polymerase delta. Mol Cell (2009) 1.52
DNA polymerase epsilon: a polymerase of unusual size (and complexity). Prog Nucleic Acid Res Mol Biol (2008) 1.44
A four-subunit DNA polymerase ζ complex containing Pol δ accessory subunits is essential for PCNA-mediated mutagenesis. Nucleic Acids Res (2012) 1.35
The efficiency and fidelity of 8-oxo-guanine bypass by DNA polymerases delta and eta. Nucleic Acids Res (2009) 1.31
Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition. Genome Res (2014) 1.23
High fidelity and lesion bypass capability of human DNA polymerase delta. Biochimie (2009) 1.22
A cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in genomic instability. Proc Natl Acad Sci U S A (2009) 1.18
A unique error signature for human DNA polymerase nu. DNA Repair (Amst) (2006) 1.16
Uracil recognition by replicative DNA polymerases is limited to the archaea, not occurring with bacteria and eukarya. Nucleic Acids Res (2007) 1.04
Characterization of a replicative DNA polymerase mutant with reduced fidelity and increased translesion synthesis capacity. Nucleic Acids Res (2008) 0.97
An alternative pathway for Okazaki fragment processing: resolution of fold-back flaps by Pif1 helicase. J Biol Chem (2010) 0.97
Error-free and mutagenic processing of topoisomerase 1-provoked damage at genomic ribonucleotides. EMBO J (2015) 0.96
Lesion bypass by S. cerevisiae Pol ζ alone. DNA Repair (Amst) (2011) 0.95
Low-fidelity DNA synthesis by the L979F mutator derivative of Saccharomyces cerevisiae DNA polymerase zeta. Nucleic Acids Res (2009) 0.94
Effects of accessory proteins on the bypass of a cis-syn thymine-thymine dimer by Saccharomyces cerevisiae DNA polymerase eta. Biochemistry (2007) 0.93
The non-canonical protein binding site at the monomer-monomer interface of yeast proliferating cell nuclear antigen (PCNA) regulates the Rev1-PCNA interaction and Polζ/Rev1-dependent translesion DNA synthesis. J Biol Chem (2011) 0.91
Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing its own infidelity. Proc Natl Acad Sci U S A (2015) 0.88
The in vitro fidelity of yeast DNA polymerase δ and polymerase ε holoenzymes during dinucleotide microsatellite DNA synthesis. DNA Repair (Amst) (2011) 0.87
Resolving individual steps of Okazaki-fragment maturation at a millisecond timescale. Nat Struct Mol Biol (2016) 0.85
Translesion DNA synthesis in the context of cancer research. Cancer Cell Int (2011) 0.82
Mutations that increase DNA binding by the processivity factor of herpes simplex virus affect virus production and DNA replication fidelity. J Virol (2009) 0.82
Reversal of a mutator activity by a nearby fidelity-neutral substitution in the RB69 DNA polymerase binding pocket. J Mol Biol (2010) 0.81
Activation of Saccharomyces cerevisiae Mlh1-Pms1 Endonuclease in a Reconstituted Mismatch Repair System. J Biol Chem (2015) 0.80
Inaccurate DNA synthesis in cell extracts of yeast producing active human DNA polymerase iota. PLoS One (2011) 0.80
Strand displacement synthesis by yeast DNA polymerase ε. Nucleic Acids Res (2016) 0.78
Regulation of yeast DNA polymerase δ-mediated strand displacement synthesis by 5'-flaps. Nucleic Acids Res (2015) 0.78
RAD51B plays an essential role during somatic and meiotic recombination in Physcomitrella. Nucleic Acids Res (2014) 0.78
Biochemical analysis of DNA polymerase η fidelity in the presence of replication protein A. PLoS One (2014) 0.77
Pif1 removes a Rap1-dependent barrier to the strand displacement activity of DNA polymerase δ. Nucleic Acids Res (2016) 0.76
Yeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiological dNTP concentrations. Nucleic Acids Res (2017) 0.75
Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism. Annu Rev Biochem (1997) 9.83
Recombinant replication protein A: expression, complex formation, and functional characterization. J Biol Chem (1994) 6.41
DNA replication fidelity. J Biol Chem (2004) 4.28
Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants. Nat Genet (1999) 4.18
An auxiliary protein for DNA polymerase-delta from fetal calf thymus. J Biol Chem (1986) 4.06
The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations. J Biol Chem (1985) 3.98
DNA polymerases that propagate the eukaryotic DNA replication fork. Crit Rev Biochem Mol Biol (2005) 3.46
Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2. J Biol Chem (2002) 2.90
Functions of replication factor C and proliferating-cell nuclear antigen: functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4. Proc Natl Acad Sci U S A (1990) 2.82
Mutagenesis by transient misalignment. J Biol Chem (1988) 2.66
Structure and processivity of two forms of Saccharomyces cerevisiae DNA polymerase delta. J Biol Chem (1998) 2.52
Analyzing fidelity of DNA polymerases. Methods Enzymol (1995) 2.52
Functions of DNA polymerases. Adv Protein Chem (2004) 2.28
The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability. Proc Natl Acad Sci U S A (2001) 2.16
Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme. EMBO J (1999) 2.00
Substrate requirements of human rhinovirus 3C protease for peptide cleavage in vitro. J Biol Chem (1990) 1.99
Mutations in yeast proliferating cell nuclear antigen define distinct sites for interaction with DNA polymerase delta and DNA polymerase epsilon. Mol Cell Biol (1997) 1.94
The fidelity of human DNA polymerase gamma with and without exonucleolytic proofreading and the p55 accessory subunit. J Biol Chem (2001) 1.92
Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice. Nat Genet (2005) 1.84
Saccharomyces cerevisiae DNA polymerase delta: high fidelity for base substitutions but lower fidelity for single- and multi-base deletions. J Biol Chem (2005) 1.80
Fidelity of Escherichia coli DNA polymerase III holoenzyme. The effects of beta, gamma complex processivity proteins and epsilon proofreading exonuclease on nucleotide misincorporation efficiencies. J Biol Chem (1997) 1.70
Unique error signature of the four-subunit yeast DNA polymerase epsilon. J Biol Chem (2003) 1.55
Saccharomyces cerevisiae pol30 (proliferating cell nuclear antigen) mutations impair replication fidelity and mismatch repair. Mol Cell Biol (1999) 1.54
Error-prone replication of repeated DNA sequences by T7 DNA polymerase in the absence of its processivity subunit. Proc Natl Acad Sci U S A (1994) 1.51
Fidelity of nucleotide incorporation by human mitochondrial DNA polymerase. J Biol Chem (2001) 1.47
Fidelity of mammalian DNA replication and replicative DNA polymerases. Biochemistry (1991) 1.43
The base substitution and frameshift fidelity of Escherichia coli DNA polymerase III holoenzyme in vitro. J Biol Chem (1998) 1.28
The large subunit of replication factor C (Rfc1p/Cdc44p) is required for DNA replication and DNA repair in Saccharomyces cerevisiae. Genetics (1996) 1.20
Dissecting the fidelity of bacteriophage RB69 DNA polymerase: site-specific modulation of fidelity by polymerase accessory proteins. Genetics (2002) 1.18
Overexpression of multisubunit replication factors in yeast. Methods (1999) 1.18
Streisinger revisited: DNA synthesis errors mediated by substrate misalignments. Cold Spring Harb Symp Quant Biol (2000) 1.17
Proliferating cell nuclear antigen promotes misincorporation catalyzed by calf thymus DNA polymerase delta. J Biol Chem (1996) 1.07
Fidelity of DNA polymerase delta holoenzyme from Saccharomyces cerevisiae: the sliding clamp proliferating cell nuclear antigen decreases its fidelity. Biochemistry (2003) 1.05
Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III. J Biol Chem (1996) 1.04
Effect of accessory proteins on T4 DNA polymerase replication fidelity. J Mol Biol (1998) 0.96
Dominant mutations in three different subunits of replication factor C suppress replication defects in yeast PCNA mutants. Genetics (1999) 0.87
Yeast DNA polymerase epsilon participates in leading-strand DNA replication. Science (2007) 4.63
Division of labor at the eukaryotic replication fork. Mol Cell (2008) 4.41
A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining. Mol Cell (2005) 3.68
A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair. Mol Cell (2010) 3.51
DNA polymerases that propagate the eukaryotic DNA replication fork. Crit Rev Biochem Mol Biol (2005) 3.46
Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases. Proc Natl Acad Sci U S A (2010) 3.44
Genome instability due to ribonucleotide incorporation into DNA. Nat Chem Biol (2010) 3.26
The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases. Cell Res (2008) 3.15
Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2. J Biol Chem (2002) 2.90
Cadmium is a mutagen that acts by inhibiting mismatch repair. Nat Genet (2003) 2.88
A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers. Nature (2011) 2.82
Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase I. Science (2011) 2.73
Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint. Proc Natl Acad Sci U S A (2003) 2.72
The PCNA-RFC families of DNA clamps and clamp loaders. Prog Nucleic Acid Res Mol Biol (2004) 2.53
Idling by DNA polymerase delta maintains a ligatable nick during lagging-strand DNA replication. Genes Dev (2004) 2.51
Preferential cis-syn thymine dimer bypass by DNA polymerase eta occurs with biased fidelity. Nature (2004) 2.40
Functions of DNA polymerases. Adv Protein Chem (2004) 2.28
Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility. Genes Dev (2003) 2.28
The checkpoint clamp activates Mec1 kinase during initiation of the DNA damage checkpoint. Mol Cell (2006) 2.27
Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes. Nat Chem Biol (2011) 2.20
The Pol32 subunit of DNA polymerase delta contains separable domains for processive replication and proliferating cell nuclear antigen (PCNA) binding. J Biol Chem (2003) 2.19
Okazaki fragment maturation in yeast. II. Cooperation between the polymerase and 3'-5'-exonuclease activities of Pol delta in the creation of a ligatable nick. J Biol Chem (2002) 2.17
RNase H2-initiated ribonucleotide excision repair. Mol Cell (2012) 2.17
Lung tumors in mice induced by "whole-life" inorganic arsenic exposure at human-relevant doses. Arch Toxicol (2014) 2.17
Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts. J Biol Chem (2003) 2.09
Saccharomyces cerevisiae MutLalpha is a mismatch repair endonuclease. J Biol Chem (2007) 2.09
A closed conformation for the Pol lambda catalytic cycle. Nat Struct Mol Biol (2004) 2.07
Mechanism of a genetic glissando: structural biology of indel mutations. Trends Biochem Sci (2006) 2.06
Evidence for preferential mismatch repair of lagging strand DNA replication errors in yeast. Curr Biol (2003) 2.03
Replication protein A directs loading of the DNA damage checkpoint clamp to 5'-DNA junctions. J Biol Chem (2006) 2.00
The X family portrait: structural insights into biological functions of X family polymerases. DNA Repair (Amst) (2007) 1.98
The efficiency and specificity of apurinic/apyrimidinic site bypass by human DNA polymerase eta and Sulfolobus solfataricus Dpo4. J Biol Chem (2003) 1.98
Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice. Cell (2007) 1.96
Yeast origins establish a strand bias for replicational mutagenesis. Mol Cell (2002) 1.90
Diet-induced obesity in male mice is associated with reduced fertility and potentiation of acrylamide-induced reproductive toxicity. Biol Reprod (2009) 1.87
An Msh2 point mutation uncouples DNA mismatch repair and apoptosis. Cancer Res (2004) 1.81
The major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conserved. PLoS Genet (2011) 1.81
Saccharomyces cerevisiae DNA polymerase delta: high fidelity for base substitutions but lower fidelity for single- and multi-base deletions. J Biol Chem (2005) 1.80
RNA-templated DNA repair. Nature (2007) 1.78
A lysine residue in the fingers subdomain of T7 DNA polymerase modulates the miscoding potential of 8-oxo-7,8-dihydroguanosine. Structure (2005) 1.76
RNase H and postreplication repair protect cells from ribonucleotides incorporated in DNA. Mol Cell (2012) 1.74
Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools. Nucleic Acids Res (2010) 1.71
Inefficient proofreading and biased error rates during inaccurate DNA synthesis by a mutant derivative of Saccharomyces cerevisiae DNA polymerase delta. J Biol Chem (2006) 1.70
DNA precursor asymmetries in mammalian tissue mitochondria and possible contribution to mutagenesis through reduced replication fidelity. Proc Natl Acad Sci U S A (2005) 1.67
Ribonucleotides are signals for mismatch repair of leading-strand replication errors. Mol Cell (2013) 1.66
Low-fidelity DNA synthesis by human DNA polymerase theta. Nucleic Acids Res (2008) 1.65
Structural insight into the substrate specificity of DNA Polymerase mu. Nat Struct Mol Biol (2006) 1.64
A structural solution for the DNA polymerase lambda-dependent repair of DNA gaps with minimal homology. Mol Cell (2004) 1.64
Mismatch repair-independent tandem repeat sequence instability resulting from ribonucleotide incorporation by DNA polymerase ε. DNA Repair (Amst) (2011) 1.63
5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpoint. Gastroenterology (2006) 1.62
The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins. Nucleic Acids Res (2006) 1.57
Exposure to hexavalent chromium resulted in significantly higher tissue chromium burden compared with trivalent chromium following similar oral doses to male F344/N rats and female B6C3F1 mice. Toxicol Sci (2010) 1.57
DNA polymerase lambda, a novel DNA repair enzyme in human cells. J Biol Chem (2002) 1.56
Unique error signature of the four-subunit yeast DNA polymerase epsilon. J Biol Chem (2003) 1.55
Proliferating cell nuclear antigen promotes translesion synthesis by DNA polymerase zeta. J Biol Chem (2005) 1.53
Topoisomerase 1-mediated removal of ribonucleotides from nascent leading-strand DNA. Mol Cell (2013) 1.53
PCNA is required for initiation of recombination-associated DNA synthesis by DNA polymerase delta. Mol Cell (2009) 1.52
The multiple biological roles of the 3'-->5' exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domains. Mol Cell Biol (2005) 1.51
The eukaryotic leading and lagging strand DNA polymerases are loaded onto primer-ends via separate mechanisms but have comparable processivity in the presence of PCNA. Nucleic Acids Res (2007) 1.49
Investigating the role of the little finger domain of Y-family DNA polymerases in low fidelity synthesis and translesion replication. J Biol Chem (2004) 1.48
Medium- and high-throughput screening of neurotoxicants using C. elegans. Neurotoxicol Teratol (2009) 1.48
Correlation of somatic hypermutation specificity and A-T base pair substitution errors by DNA polymerase eta during copying of a mouse immunoglobulin kappa light chain transgene. Proc Natl Acad Sci U S A (2002) 1.46
Differential correction of lagging-strand replication errors made by DNA polymerases {alpha} and {delta}. Proc Natl Acad Sci U S A (2010) 1.45
Replication protein A-directed unloading of PCNA by the Ctf18 cohesion establishment complex. Mol Cell Biol (2005) 1.45
DNA polymerase epsilon: a polymerase of unusual size (and complexity). Prog Nucleic Acid Res Mol Biol (2008) 1.44
Pif1 helicase directs eukaryotic Okazaki fragments toward the two-nuclease cleavage pathway for primer removal. J Biol Chem (2008) 1.43
Biological and biochemical consequences of global deletion of exon 3 from the ER alpha gene. FASEB J (2010) 1.42
Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase. Cell (2006) 1.41
A novel function of DNA polymerase zeta regulated by PCNA. EMBO J (2006) 1.40
Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer. Proc Natl Acad Sci U S A (2006) 1.40
The frameshift infidelity of human DNA polymerase lambda. Implications for function. J Biol Chem (2003) 1.39
A ubiquitin-binding motif in the translesion DNA polymerase Rev1 mediates its essential functional interaction with ubiquitinated proliferating cell nuclear antigen in response to DNA damage. J Biol Chem (2007) 1.39
Direct visualization of asymmetric adenine-nucleotide-induced conformational changes in MutL alpha. Mol Cell (2008) 1.38
An international study of research misconduct policies. Account Res (2015) 1.37
Genome-wide model for the normal eukaryotic DNA replication fork. Proc Natl Acad Sci U S A (2010) 1.36
Clusters of mutations from transient hypermutability. Proc Natl Acad Sci U S A (2005) 1.35
Mismatch repair balances leading and lagging strand DNA replication fidelity. PLoS Genet (2012) 1.34
Active site mutation in DNA polymerase gamma associated with progressive external ophthalmoplegia causes error-prone DNA synthesis. J Biol Chem (2002) 1.34
Biochemical properties of Saccharomyces cerevisiae DNA polymerase IV. J Biol Chem (2005) 1.34
Low fidelity DNA synthesis by a y family DNA polymerase due to misalignment in the active site. J Biol Chem (2002) 1.33
Regulation of B family DNA polymerase fidelity by a conserved active site residue: characterization of M644W, M644L and M644F mutants of yeast DNA polymerase epsilon. Nucleic Acids Res (2007) 1.33
The efficiency and fidelity of 8-oxo-guanine bypass by DNA polymerases delta and eta. Nucleic Acids Res (2009) 1.31
Retraction policies of top scientific journals ranked by impact factor. J Med Libr Assoc (2015) 1.31
Enzymatic switching for efficient and accurate translesion DNA replication. Nucleic Acids Res (2004) 1.30
Replication infidelity via a mismatch with Watson-Crick geometry. Proc Natl Acad Sci U S A (2011) 1.30