Published in Nucleic Acids Res on September 23, 2014
Oncogenic cancer/testis antigens: prime candidates for immunotherapy. Oncotarget (2015) 1.07
Polycomb repressive complex 2 facilitates the nuclear export of the influenza viral genome through the interaction with M1. Sci Rep (2016) 0.78
Role of EZH2 histone methyltrasferase in melanoma progression and metastasis. Cancer Biol Ther (2016) 0.75
Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis. Mol Cancer (2017) 0.75
Multicellular tumor spheroids of human uveal melanoma induce genes associated with anoikis resistance, lipogenesis, and SSXs. Mol Vis (2017) 0.75
The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature (1999) 12.60
Role of histone H2A ubiquitination in Polycomb silencing. Nature (2004) 9.48
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells. Genes Dev (2007) 6.77
Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res (2008) 4.64
Polycomb-dependent regulatory contacts between distant Hox loci in Drosophila. Cell (2011) 4.29
EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast. J Clin Oncol (2005) 4.24
Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma. Nat Genet (1994) 3.10
EZH2 is essential for glioblastoma cancer stem cell maintenance. Cancer Res (2009) 2.68
Biochemical mechanisms of gene regulation by polycomb group protein complexes. Curr Opin Genet Dev (2009) 2.63
EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation. Proc Natl Acad Sci U S A (2009) 2.25
SWI/SNF mediates polycomb eviction and epigenetic reprogramming of the INK4b-ARF-INK4a locus. Mol Cell Biol (2008) 2.14
Tissue-specific TAFs counteract Polycomb to turn on terminal differentiation. Science (2005) 2.13
Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer. Clin Cancer Res (2006) 2.10
Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma. Cell (2013) 2.05
Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics. Cancer Cell (2012) 1.99
Throwing the cancer switch: reciprocal roles of polycomb and trithorax proteins. Nat Rev Cancer (2010) 1.93
Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion. Proc Natl Acad Sci U S A (2008) 1.90
BMI1 sustains human glioblastoma multiforme stem cell renewal. J Neurosci (2009) 1.85
BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair. J Cell Biol (2010) 1.74
Roles of the Polycomb group proteins in stem cells and cancer. Cell Death Dis (2011) 1.70
Consistent expression of the stem cell renewal factor BMI-1 in primary and metastatic melanoma. Int J Cancer (2007) 1.62
Insulators, not Polycomb response elements, are required for long-range interactions between Polycomb targets in Drosophila melanogaster. Mol Cell Biol (2010) 1.47
Polycomb protein EZH2 regulates E2F1-dependent apoptosis through epigenetically modulating Bim expression. Cell Death Differ (2009) 1.44
Tumorigenic heterogeneity in cancer stem cells evolved from long-term cultures of telomerase-immortalized human mesenchymal stem cells. Cancer Res (2005) 1.41
Molecular mechanisms underlying human synovial sarcoma development. Genes Chromosomes Cancer (2001) 1.39
A view of nuclear Polycomb bodies. Curr Opin Genet Dev (2011) 1.31
Histone deacetylase inhibitors reverse SS18-SSX-mediated polycomb silencing of the tumor suppressor early growth response 1 in synovial sarcoma. Cancer Res (2008) 1.28
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Repression of BMI1 in normal and leukemic human CD34(+) cells impairs self-renewal and induces apoptosis. Blood (2009) 1.24
Heterogeneous expression of the SSX cancer/testis antigens in human melanoma lesions and cell lines. Cancer Res (2000) 1.22
SSX and the synovial-sarcoma-specific chimaeric protein SYT-SSX co-localize with the human Polycomb group complex. Oncogene (1999) 1.22
The Mcp element mediates stable long-range chromosome-chromosome interactions in Drosophila. Mol Biol Cell (2006) 1.21
An anticlastogenic function for the Polycomb Group gene Bmi1. Proc Natl Acad Sci U S A (2011) 1.17
Association of SYT-SSX fusion types with proliferative activity and prognosis in synovial sarcoma. Mod Pathol (2000) 1.16
Prospective study on the expression of cancer testis genes and antibody responses in 100 consecutive patients with primary breast cancer. Int J Cancer (2006) 1.14
Clinical significance of enhancer of zeste homolog 2 expression in colorectal cancer cases. Eur J Surg Oncol (2005) 1.09
The Polycomb group protein Bmi-1 is essential for the growth of multiple myeloma cells. Cancer Res (2010) 1.09
Polycomb protein EZH2 regulates cancer cell fate decision in response to DNA damage. Cell Death Differ (2011) 1.07
Restriction of GAGE protein expression to subpopulations of cancer cells is independent of genotype and may limit the use of GAGE proteins as targets for cancer immunotherapy. Br J Cancer (2006) 1.04
SUZ12 promotes human epithelial ovarian cancer by suppressing apoptosis via silencing HRK. Mol Cancer Res (2012) 1.03
Loss of BMI-1 expression is associated with clinical progress of malignant melanoma. Mod Pathol (2008) 1.00
Polycomb: a paradigm for genome organization from one to three dimensions. Curr Opin Cell Biol (2012) 1.00
Overexpression of BMI-1 promotes cell growth and resistance to cisplatin treatment in osteosarcoma. PLoS One (2011) 1.00
Expression of polycomb group protein EZH2 in nevi and melanoma. J Cutan Pathol (2007) 0.97
The expression of MAGE and SSX, and correlation of COX2, VEGF, and survivin in colorectal cancer. Anticancer Res (2012) 0.96
Reprogramming of mesenchymal stem cells by the synovial sarcoma-associated oncogene SYT-SSX2. Oncogene (2011) 0.96
Genome-wide recruitment to Polycomb-modified chromatin and activity regulation of the synovial sarcoma oncogene SYT-SSX2. BMC Genomics (2012) 0.93
Association between Bmi1 and clinicopathological status of esophageal squamous cell carcinoma. World J Gastroenterol (2009) 0.91
Melanoma-associated antigens recognized by cytotoxic T lymphocytes. APMIS (1998) 0.90
The synovial sarcoma-associated SYT-SSX2 oncogene antagonizes the polycomb complex protein Bmi1. PLoS One (2009) 0.85
EZH2-mediated epigenetic repression of DNA repair in promoting breast tumor initiating cells. Breast Cancer Res (2011) 0.83