Published in Mol Biol Cell on February 22, 2006
The genetic signatures of noncoding RNAs. PLoS Genet (2009) 6.72
On emerging nuclear order. J Cell Biol (2011) 1.77
Interactions among Polycomb domains are guided by chromosome architecture. PLoS Genet (2011) 1.76
Stalled Hox promoters as chromosomal boundaries. Genes Dev (2009) 1.55
Insulators, not Polycomb response elements, are required for long-range interactions between Polycomb targets in Drosophila melanogaster. Mol Cell Biol (2010) 1.47
Polycomb group response elements in Drosophila and vertebrates. Adv Genet (2013) 1.43
Drosophila telomeres: an exception providing new insights. Bioessays (2008) 1.39
A view of nuclear Polycomb bodies. Curr Opin Genet Dev (2011) 1.31
Study of the functional interaction between Mcp insulators from the Drosophila bithorax complex: effects of insulator pairing on enhancer-promoter communication. Mol Cell Biol (2007) 1.29
Interchromosomal association and gene regulation in trans. Trends Genet (2010) 1.26
The yin and yang of chromatin spatial organization. Genome Biol (2010) 1.20
Making connections: insulators organize eukaryotic chromosomes into independent cis-regulatory networks. Bioessays (2013) 1.13
Do chromatin loops provide epigenetic gene expression states? Curr Opin Genet Dev (2010) 1.12
Functional interaction between the Fab-7 and Fab-8 boundaries and the upstream promoter region in the Drosophila Abd-B gene. Mol Cell Biol (2008) 1.09
Disruption of topoisomerase II perturbs pairing in drosophila cell culture. Genetics (2007) 1.08
A chromatin insulator mediates transgene homing and very long-range enhancer-promoter communication. Development (2009) 1.04
Insulators target active genes to transcription factories and polycomb-repressed genes to polycomb bodies. PLoS Genet (2013) 1.03
Progressive polycomb assembly on H3K27me3 compartments generates polycomb bodies with developmentally regulated motion. PLoS Genet (2012) 1.00
Two new insulator proteins, Pita and ZIPIC, target CP190 to chromatin. Genome Res (2014) 0.99
Enhancer blocking and transvection at the Drosophila apterous locus. Genetics (2008) 0.99
Red flag on the white reporter: a versatile insulator abuts the white gene in Drosophila and is omnipresent in mini-white constructs. Nucleic Acids Res (2007) 0.99
Surviving an identity crisis: a revised view of chromatin insulators in the genomics era. Biochim Biophys Acta (2013) 0.98
The nuclear organization of Polycomb/Trithorax group response elements in larval tissues of Drosophila melanogaster. Chromosome Res (2008) 0.97
Are we there yet? Initial targeting of the Male-Specific Lethal and Polycomb group chromatin complexes in Drosophila. Open Biol (2014) 0.96
Functional sub-division of the Drosophila genome via chromatin looping: the emerging importance of CP190. Nucleus (2013) 0.88
A genomewide survey argues that every zygotic gene product is dispensable for the initiation of somatic homolog pairing in Drosophila. Genetics (2008) 0.86
Effects of chromosomal rearrangements on transvection at the yellow gene of Drosophila melanogaster. Genetics (2009) 0.84
Interchromosomal clustering of active genes at the nuclear pore complex. Nucleus (2012) 0.83
Transcriptional activity of the telomeric retrotransposon HeT-A in Drosophila melanogaster is stimulated as a consequence of subterminal deficiencies at homologous and nonhomologous telomeres. Mol Cell Biol (2007) 0.83
Determinants of Chromosome Architecture: Insulator Pairing in cis and in trans. PLoS Genet (2016) 0.82
Functional Requirements for Fab-7 Boundary Activity in the Bithorax Complex. Mol Cell Biol (2015) 0.79
SSX2 is a novel DNA-binding protein that antagonizes polycomb group body formation and gene repression. Nucleic Acids Res (2014) 0.78
Functional Dissection of the Blocking and Bypass Activities of the Fab-8 Boundary in the Drosophila Bithorax Complex. PLoS Genet (2016) 0.77
The boundary paradox in the Bithorax complex. Mech Dev (2015) 0.77
Architectural proteins Pita, Zw5,and ZIPIC contain homodimerization domain and support specific long-range interactions in Drosophila. Nucleic Acids Res (2016) 0.76
Formation of a Polycomb-Domain in the Absence of Strong Polycomb Response Elements. PLoS Genet (2016) 0.75
Boundaries of loop domains (insulators): Determinants of chromosome form and function in multicellular eukaryotes. Bioessays (2017) 0.75
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development (1993) 58.26
Genetic transformation of Drosophila with transposable element vectors. Science (1982) 27.36
A gene complex controlling segmentation in Drosophila. Nature (1978) 23.75
A stable genomic source of P element transposase in Drosophila melanogaster. Genetics (1988) 15.43
Interchromosomal associations between alternatively expressed loci. Nature (2005) 7.45
In vivo localization of DNA sequences and visualization of large-scale chromatin organization using lac operator/repressor recognition. J Cell Biol (1996) 6.78
GFP tagging of budding yeast chromosomes reveals that protein-protein interactions can mediate sister chromatid cohesion. Curr Biol (1996) 6.49
Dot1p modulates silencing in yeast by methylation of the nucleosome core. Cell (2002) 6.29
Long-range intrachromosomal interactions in the T helper type 2 cytokine locus. Nat Immunol (2004) 4.67
Transcription complex stability and chromatin dynamics in vivo. Nature (1995) 4.51
Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae. Genetics (1998) 4.42
The abdominal region of the bithorax complex. Cell (1985) 4.02
Lysine-79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: a potential mechanism for position-effect variegation. Proc Natl Acad Sci U S A (2003) 3.09
The role of EKLF in human beta-globin gene competition. Genes Dev (1996) 2.72
Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase. J Biol Chem (2002) 2.56
The dynamics of homologous chromosome pairing during male Drosophila meiosis. Curr Biol (2002) 2.42
Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus. Curr Biol (2001) 2.37
A new homeotic mutation in the Drosophila bithorax complex removes a boundary separating two domains of regulation. EMBO J (1990) 2.37
Transvection effects in Drosophila. Annu Rev Genet (2002) 2.18
Homologous chromosome pairing in Drosophila melanogaster proceeds through multiple independent initiations. J Cell Biol (1998) 2.16
Inheritance of Polycomb-dependent chromosomal interactions in Drosophila. Genes Dev (2003) 2.07
Silencers in abdominal-B, a homeotic Drosophila gene. EMBO J (1993) 2.03
Mcp and Fab-7: molecular analysis of putative boundaries of cis-regulatory domains in the bithorax complex of Drosophila melanogaster. Nucleic Acids Res (1994) 2.00
Role for the silencing protein Dot1 in meiotic checkpoint control. Mol Biol Cell (2000) 1.93
Chromatin insulator elements block the silencing of a target gene by the Drosophila polycomb response element (PRE) but allow trans interactions between PREs on different chromosomes. Genetics (1997) 1.92
Chromatin domain boundaries in the Bithorax complex. Cell Mol Life Sci (1998) 1.74
The mcp element from the Drosophila melanogaster bithorax complex mediates long-distance regulatory interactions. Genetics (1999) 1.67
Genome-wide histone modifications: gaining specificity by preventing promiscuity. Curr Opin Cell Biol (2002) 1.50
Pairing-sensitive silencing, polycomb group response elements, and transposon homing in Drosophila. Adv Genet (2002) 1.49
Transvection in the iab-5,6,7 region of the bithorax complex of Drosophila: homology independent interactions in trans. Genetics (1995) 1.43
Characterization of the grappa gene, the Drosophila histone H3 lysine 79 methyltransferase. Genetics (2004) 1.42
Reduction of transcription by homologue asynapsis in Drosophila imaginal discs. Nature (1996) 1.25
A silencer is required for maintenance of transcriptional repression throughout Drosophila development. Development (1997) 1.23
Genetic and molecular analysis of chromatin domains. Cold Spring Harb Symp Quant Biol (1993) 1.20
Homologous association of the Bithorax-Complex during embryogenesis: consequences for transvection in Drosophila melanogaster. Development (1998) 1.20
Dosage compensation of the Drosophila white gene requires both the X chromosome environment and multiple intragenic elements. Genetics (1995) 1.16
Transvection and chromosomal trans-interaction effects. Biochim Biophys Acta (1999) 1.01
Spindles and centrosomes during male meiosis in Drosophila melanogaster. Eur J Cell Biol (1990) 0.95
The 3' regulatory region of the Abdominal-B gene: genetic analysis supports a model of reiterated and interchangeable regulatory elements. Genetics (1993) 0.84
Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (2010) 12.39
Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell (2002) 12.28
Polycomb silencing mechanisms and the management of genomic programmes. Nat Rev Genet (2007) 7.61
Comprehensive analysis of the chromatin landscape in Drosophila melanogaster. Nature (2010) 6.87
Three-dimensional resolution doubling in wide-field fluorescence microscopy by structured illumination. Biophys J (2008) 6.86
Role of the polycomb protein EED in the propagation of repressive histone marks. Nature (2009) 6.62
Genome-wide analysis of Polycomb targets in Drosophila melanogaster. Nat Genet (2006) 6.48
Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy. Science (2008) 6.47
Polycomb complexes and epigenetic states. Curr Opin Cell Biol (2008) 3.81
An assessment of histone-modification antibody quality. Nat Struct Mol Biol (2010) 3.72
Cell-wall recovery after irreversible deformation of wood. Nat Mater (2003) 3.09
Polycomb silencing blocks transcription initiation. Mol Cell (2004) 2.96
Ezh2 requires PHF1 to efficiently catalyze H3 lysine 27 trimethylation in vivo. Mol Cell Biol (2008) 2.93
Association of cohesin and Nipped-B with transcriptionally active regions of the Drosophila melanogaster genome. Chromosoma (2007) 2.73
CHD1 motor protein is required for deposition of histone variant H3.3 into chromatin in vivo. Science (2007) 2.71
Carrageenan is a potent inhibitor of papillomavirus infection. PLoS Pathog (2006) 2.65
JAK2-V617F mutation in a patient with Philadelphia-chromosome-positive chronic myeloid leukaemia. Lancet Oncol (2007) 2.44
The dynamics of homologous chromosome pairing during male Drosophila meiosis. Curr Biol (2002) 2.42
UCSF tomography: an integrated software suite for real-time electron microscopic tomographic data collection, alignment, and reconstruction. J Struct Biol (2006) 2.26
Fast live simultaneous multiwavelength four-dimensional optical microscopy. Proc Natl Acad Sci U S A (2010) 2.17
Alternative epigenetic chromatin states of polycomb target genes. PLoS Genet (2010) 2.15
HPV antibody detection by ELISA with capsid protein L1 fused to glutathione S-transferase. J Virol Methods (2002) 1.97
Synthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaques. PLoS Pathog (2009) 1.92
Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin. Genome Res (2010) 1.87
An improved strategy for automated electron microscopic tomography. J Struct Biol (2004) 1.86
Oxidation-responsive polymeric vesicles. Nat Mater (2004) 1.82
N-terminal processing of proteins exported by malaria parasites. Mol Biochem Parasitol (2008) 1.81
Polycomb complexes and the propagation of the methylation mark at the Drosophila ubx gene. J Biol Chem (2006) 1.78
Nature and function of insulator protein binding sites in the Drosophila genome. Genome Res (2012) 1.77
I5S: wide-field light microscopy with 100-nm-scale resolution in three dimensions. Biophys J (2008) 1.70
A presynaptic giant ankyrin stabilizes the NMJ through regulation of presynaptic microtubules and transsynaptic cell adhesion. Neuron (2008) 1.69
A new world of Polycombs: unexpected partnerships and emerging functions. Nat Rev Genet (2013) 1.67
RIM-binding protein, a central part of the active zone, is essential for neurotransmitter release. Science (2011) 1.59
Regulation of the Drosophila Enhancer of split and invected-engrailed gene complexes by sister chromatid cohesion proteins. PLoS One (2009) 1.58
An endogenous Su(Hw) insulator separates the yellow gene from the Achaete-scute gene complex in Drosophila. Development (2003) 1.52
Insulators, not Polycomb response elements, are required for long-range interactions between Polycomb targets in Drosophila melanogaster. Mol Cell Biol (2010) 1.47
The Drosophila trithorax protein is a coactivator required to prevent re-establishment of polycomb silencing. Development (2002) 1.45
Reelin deficiency and displacement of mature neurons, but not neurogenesis, underlie the formation of granule cell dispersion in the epileptic hippocampus. J Neurosci (2006) 1.45
In vitro versus in vivo cellulose microfibrils from plant primary wall synthases: structural differences. J Biol Chem (2002) 1.44
AIDA: an adaptive image deconvolution algorithm with application to multi-frame and three-dimensional data. J Opt Soc Am A Opt Image Sci Vis (2007) 1.36
Reactivity pattern of 92 monoclonal antibodies with 15 human papillomavirus types. J Gen Virol (2008) 1.35
The significance of direct sunlight and polarized skylight in the ant's celestial system of navigation. Proc Natl Acad Sci U S A (2006) 1.35
Nuclear translocation of papillomavirus minor capsid protein L2 requires Hsc70. J Virol (2004) 1.27
The three-dimensional structure of in vitro reconstituted Xenopus laevis chromosomes by EM tomography. Chromosoma (2007) 1.24
ESC, ESCL and their roles in Polycomb Group mechanisms. Mech Dev (2008) 1.23
Characteristic low density and shear sensitivity of cross-linked chromatin containing polycomb complexes. Mol Cell Biol (2005) 1.22
Prediction of left ventricular remodeling and analysis of infarct resorption in patients with reperfused myocardial infarcts by using contrast-enhanced MR imaging. Radiology (2007) 1.21
Condensed mitotic chromosome structure at nanometer resolution using PALM and EGFP- histones. PLoS One (2010) 1.21
Homeostatic control of presynaptic neurotransmitter release. Annu Rev Physiol (2014) 1.16
Production of human papillomavirus type 16 virus-like particles in transgenic plants. J Virol (2003) 1.15
Human dimensions of forest disturbance by insects: an international synthesis. Environ Manage (2008) 1.14
Rapid telomere motions in live human cells analyzed by highly time-resolved microscopy. Epigenetics Chromatin (2008) 1.13
Codon optimization of the human papillomavirus 11 (HPV 11) L1 gene leads to increased gene expression and formation of virus-like particles in mammalian epithelial cells. Virology (2004) 1.13
Human papillomavirus type 16 L1 capsomeres induce L1-specific cytotoxic T lymphocytes and tumor regression in C57BL/6 mice. J Virol (2003) 1.12
Checkers is solved. Science (2007) 1.10
Development of AAVLP(HPV16/31L2) particles as broadly protective HPV vaccine candidate. PLoS One (2012) 1.08
Upregulation of inward rectifier K+ (Kir2) channels in dentate gyrus granule cells in temporal lobe epilepsy. J Physiol (2009) 1.08
Intranasal vaccination with recombinant adeno-associated virus type 5 against human papillomavirus type 16 L1. J Virol (2006) 1.06
Mechanical properties of silk: interplay of deformation on macroscopic and molecular length scales. Phys Rev Lett (2008) 1.05
Coordinated binding of Vps4 to ESCRT-III drives membrane neck constriction during MVB vesicle formation. J Cell Biol (2014) 1.05
Potent anti-HPV immune responses induced by tandem repeats of the HPV16 L2 (20 -- 38) peptide displayed on bacterial thioredoxin. Vaccine (2009) 1.05
Characterization of the mechanical properties of qPlus sensors. Beilstein J Nanotechnol (2013) 1.05
The N-terminal region of the human papillomavirus L2 protein contains overlapping binding sites for neutralizing, cross-neutralizing and non-neutralizing antibodies. Virology (2010) 1.04
Sequence-specific targeting of dosage compensation in Drosophila favors an active chromatin context. PLoS Genet (2012) 1.04
Insulators target active genes to transcription factories and polycomb-repressed genes to polycomb bodies. PLoS Genet (2013) 1.03
DNA-vaccination via tattooing induces stronger humoral and cellular immune responses than intramuscular delivery supported by molecular adjuvants. Genet Vaccines Ther (2008) 1.03
Long-range interphase chromosome organization in Drosophila: a study using color barcoded fluorescence in situ hybridization and structural clustering analysis. Mol Biol Cell (2004) 1.03
A presynaptic ENaC channel drives homeostatic plasticity. Neuron (2013) 1.03
Increasing amino acid supply in pea embryos reveals specific interactions of N and C metabolism, and highlights the importance of mitochondrial metabolism. Plant J (2008) 1.02
Distribution and determinants of functioning and disability in aged adults--results from the German KORA-Age study. BMC Public Health (2013) 1.02
The human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter. J Exp Med (2013) 1.01
Modelling the application of adaptive optics to wide-field microscope live imaging. J Microsc (2007) 1.00
Determination of insecticidal Cry1Ab protein in soil collected in the final growing seasons of a nine-year field trial of Bt-maize MON810. Transgenic Res (2011) 0.99
Enhancer blocking and transvection at the Drosophila apterous locus. Genetics (2008) 0.99
Automated acquisition of electron microscopic random conical tilt sets. J Struct Biol (2006) 0.99
TBX3 Directs Cell-Fate Decision toward Mesendoderm. Stem Cell Reports (2013) 0.98
Integrity of the Mod(mdg4)-67.2 BTB domain is critical to insulator function in Drosophila melanogaster. Mol Cell Biol (2006) 0.98
Intranasal vaccination with AAV5 and 9 vectors against human papillomavirus type 16 in rhesus macaques. Hum Gene Ther (2012) 0.98
The prevalence of injection-site reactions with disease-modifying therapies and their effect on adherence in patients with multiple sclerosis: an observational study. BMC Neurol (2011) 0.98
Enrichment of HP1a on Drosophila chromosome 4 genes creates an alternate chromatin structure critical for regulation in this heterochromatic domain. PLoS Genet (2012) 0.97
High-resolution restoration of 3D structures from widefield images with extreme low signal-to-noise-ratio. Proc Natl Acad Sci U S A (2013) 0.96
Graphical models illustrated complex associations between variables describing human functioning. J Clin Epidemiol (2009) 0.95
Generalized epidemic process and tricritical dynamic percolation. Phys Rev E Stat Nonlin Soft Matter Phys (2004) 0.95
Conformational and dynamical properties of disaccharides in water: a molecular dynamics study. Biophys J (2006) 0.95
Glial-derived prodegenerative signaling in the Drosophila neuromuscular system. Neuron (2011) 0.94
4G/5G promoter polymorphism in the plasminogen-activator-inhibitor-1 gene in children with systemic meningococcaemia. Eur J Pediatr (2005) 0.94
Amino acid metabolism at the maternal-filial boundary of young barley seeds: a microdissection-based study. Planta (2009) 0.94
High-throughput pseudovirion-based neutralization assay for analysis of natural and vaccine-induced antibodies against human papillomaviruses. PLoS One (2013) 0.93
The ICF forms a useful framework for classifying individual patient goals in post-acute rehabilitation. J Rehabil Med (2011) 0.93
Extensive conservation of sequences and chromatin structures in the bxd polycomb response element among Drosophilid species. Int J Dev Biol (2002) 0.92
Phase retrieval for high-numerical-aperture optical systems. Opt Lett (2003) 0.92
Oral immunization with different assembly forms of the HPV 16 major capsid protein L1 induces neutralizing antibodies and cytotoxic T-lymphocytes. Virology (2007) 0.92
Patient goals in post-acute geriatric rehabilitation--goal attainment is an indicator for improved functioning. J Rehabil Med (2011) 0.92
Evidence of activity-specific, radial organization of mitotic chromosomes in Drosophila. PLoS Biol (2011) 0.91
The ThioredoxinT and deadhead gene pair encode testis- and ovary-specific thioredoxins in Drosophila melanogaster. Chromosoma (2003) 0.91