Immunological tolerance: new approaches using transgenic mice.

PubWeight™: 1.25‹?› | Rank: Top 10%

🔗 View Article (PMID 2526641)

Published in Immunol Today on February 01, 1989

Authors

J F Miller, G Morahan, J Allison

Articles by these authors

High efficiency transformation of E. coli by high voltage electroporation. Nucleic Acids Res (1988) 34.78

Cell to cell interaction in the immune response. II. The source of hemolysin-forming cells in irradiated mice given bone marrow and thymus or thoracic duct lymphocytes. J Exp Med (1968) 12.91

Help for cytotoxic-T-cell responses is mediated by CD40 signalling. Nature (1998) 11.08

Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements. Immunol Cell Biol (1998) 11.07

Cell to cell interaction in the immune response. I. Hemolysin-forming cells in neonatally thymectomized mice reconstituted with thymus or thoracic duct lymphocytes. J Exp Med (1968) 9.67

Thymus and antigen-reactive cells. Transplant Rev (1969) 8.84

Current concepts of the immunological function of the thymus. Physiol Rev (1967) 8.37

Immunological activity of thymus and thoracic-duct lymphocytes. Proc Natl Acad Sci U S A (1968) 7.49

A receptor for antibody on B lymphocytes. I. Method of detection and functional significance. J Exp Med (1972) 7.47

Class I-restricted cross-presentation of exogenous self-antigens leads to deletion of autoreactive CD8(+) T cells. J Exp Med (1997) 5.72

Constitutive class I-restricted exogenous presentation of self antigens in vivo. J Exp Med (1996) 5.21

Cell to cell interaction in the immune response. 3. Chromosomal marker analysis of single antibody-forming cells in reconstituted, irradiated, or thymectomized mice. J Exp Med (1968) 5.02

Sequences required for expression of Bordetella pertussis virulence factors share homology with prokaryotic signal transduction proteins. Proc Natl Acad Sci U S A (1989) 4.78

Specific inactivation of thymus-derived (T) and non-thymus-derived (B) lymphocytes by 125I-labelled antigen. Nat New Biol (1971) 4.55

Induction of a CD8+ cytotoxic T lymphocyte response by cross-priming requires cognate CD4+ T cell help. J Exp Med (1997) 4.01

The thymus and the precursors of antigen reactive cells. Nature (1967) 3.92

Role of major histocompatibility complex gene products in delayed-type hypersensitivity. Proc Natl Acad Sci U S A (1976) 3.69

Cellular basis of the immunological defects in thymectomized mice. Nature (1967) 3.69

Ectopic expression of the flagellar regulon alters development of the Bordetella-host interaction. Cell (1995) 3.64

BvgAS-mediated signal transduction: analysis of phase-locked regulatory mutants of Bordetella bronchiseptica in a rabbit model. Infect Immun (1994) 3.44

Antigen-induced selective recruitment of circulating lymphocytes. Cell Immunol (1971) 3.35

H-2 gene complex restricts transfer of delayed-type hypersensitivity in mice. Proc Natl Acad Sci U S A (1975) 3.34

Regeneration of thymus grafts. I. Histological and cytological aspects. Transplantation (1965) 3.29

Roles for motility in bacterial-host interactions. Mol Microbiol (1997) 3.16

Cell to cell interaction in the immune response. IV. Site of action of antilymphocyte globulin. J Exp Med (1968) 3.16

Cell-to-cell interaction in the immune response. VI. Contribution of thymus-derived cells and antibody-forming cell precursors to immunological memory. J Exp Med (1971) 3.14

T cell-dependent suppression of an anti-hapten antibody response. Transplant Rev (1975) 3.06

Interaction between lymphocytes in immune responses. Cell Immunol (1971) 3.03

Ly and Ia antigen phenotypes of T cells involved in delayed-type hypersensitivity and in suppression. J Exp Med (1976) 3.00

Early embryonic mortality in women. Fertil Steril (1982) 2.92

Cell-to-cell interaction in the immune response. X. T-cell-dependent suppression in tolerant mice. J Exp Med (1974) 2.77

Fetal loss after implantation. A prospective study. Lancet (1980) 2.73

Dysmyelination in transgenic mice resulting from expression of class I histocompatibility molecules in oligodendrocytes. Nature (1991) 2.67

Screening for receptor ligands using large libraries of peptides linked to the C terminus of the lac repressor. Proc Natl Acad Sci U S A (1992) 2.67

Recombinant Listeria monocytogenes as a live vaccine vehicle for the induction of protective anti-viral cell-mediated immunity. Proc Natl Acad Sci U S A (1995) 2.66

A radioisotopic method to measure delayed type hypersensitivity in the mouse. I. Studies in sensitized and normal mice. Int Arch Allergy Appl Immunol (1975) 2.64

Compartmentalization of bacterial antigens: differential effects on priming of CD8 T cells and protective immunity. Cell (1998) 2.59

Contrast, induction, facilitation, suppression, and conservation. J Exp Anal Behav (1976) 2.50

CD4+ T cell help impairs CD8+ T cell deletion induced by cross-presentation of self-antigens and favors autoimmunity. J Exp Med (1997) 2.49

Diabetes in transgenic mice resulting from over-expression of class I histocompatibility molecules in pancreatic beta cells. Nature (1988) 2.46

Integration of multiple domains in a two-component sensor protein: the Bordetella pertussis BvgAS phosphorelay. EMBO J (1996) 2.41

Growth of B-lymphocyte colonies in vitro. J Exp Med (1975) 2.41

Peripheral deletion of self-reactive B cells. Nature (1991) 2.34

The bvgAS locus negatively controls motility and synthesis of flagella in Bordetella bronchiseptica. J Bacteriol (1992) 2.33

The bvgA gene of Bordetella pertussis encodes a transcriptional activator required for coordinate regulation of several virulence genes. J Bacteriol (1989) 2.29

Activation of thymus cells by histocompatibility antigens. Nat New Biol (1971) 2.26

The role of the thymus and recent thymic migrants in the maintenance of the adult peripheral lymphocyte pool. J Exp Med (1998) 2.25

Major histocompatibility complex class I-restricted cross-presentation is biased towards high dose antigens and those released during cellular destruction. J Exp Med (1998) 2.24

Growth of B lymphocyte colonies in vitro from mouse lymphoid organs. Nature (1975) 2.24

Tolerance of class I histocompatibility antigens expressed extrathymically. Nature (1989) 2.19

Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice. Diabetes (1997) 2.19

MICROBIOME. A unified initiative to harness Earth's microbiomes. Science (2015) 2.15

Enrichment of specific suppressor T cells and characterization of their surface markers. J Exp Med (1977) 2.13

Development of the Leeds Dependence Questionnaire (LDQ): a questionnaire to measure alcohol and opiate dependence in the context of a treatment evaluation package. Addiction (1994) 2.11

Thymus-derived cells in mouse thoracic duct lymph. Nat New Biol (1971) 2.07

The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. Cell (1983) 2.04

A mutation in the Bordetella bronchiseptica bvgS gene results in reduced virulence and increased resistance to starvation, and identifies a new class of Bvg-regulated antigens. Mol Microbiol (1997) 2.01

Specific suppressive factors produced by hybridomas derived from the fusion of enriched suppressor T cells and a T lymphoma cell line. J Exp Med (1978) 2.01

The BvgAS virulence control system regulates type III secretion in Bordetella bronchiseptica. Mol Microbiol (1998) 1.99

Characterization of the ovalbumin-specific TCR transgenic line OT-I: MHC elements for positive and negative selection. Immunol Cell Biol (2000) 1.98

Flagellin gene transcription in Bordetella bronchiseptica is regulated by the BvgAS virulence control system. J Bacteriol (1993) 1.94

Autoimmune diabetes as a consequence of locally produced interleukin-2. Nature (1992) 1.92

Effect of thymectomy in adult mice on immunological responsiveness. Nature (1965) 1.91

Receptor for antibody-antigen complexes used to separate T cells from B cells. Nat New Biol (1972) 1.87

Prevention of diabetes in non-obese diabetic I-Ak transgenic mice. Nature (1990) 1.87

The immune response of normal, irradiated and thymectomized mice to fowl immunoglobulin G as detected by a hemolytic plaque technique. Int Arch Allergy Appl Immunol (1971) 1.85

Pregenomic comparative analysis between bordetella bronchiseptica RB50 and Bordetella pertussis tohama I in murine models of respiratory tract infection. Infect Immun (1999) 1.83

Cross-tolerance: a pathway for inducing tolerance to peripheral tissue antigens. J Exp Med (1998) 1.83

Cross-presentation: a general mechanism for CTL immunity and tolerance. Immunol Today (1998) 1.82

Too much of a good thing: why it is bad to stimulate the beta cell to secrete insulin. Diabetologia (2008) 1.79

Interaction of thymus lymphocytes with histoincompatible cells. II. Recirculating lymphocytes derived from antigen-activated thymus cells. Cell Immunol (1972) 1.78

Multiple roles for Bordetella lipopolysaccharide molecules during respiratory tract infection. Infect Immun (2000) 1.77

Probing the function of Bordetella bronchiseptica adenylate cyclase toxin by manipulating host immunity. Infect Immun (1999) 1.76

Filamentous hemagglutinin of Bordetella bronchiseptica is required for efficient establishment of tracheal colonization. Infect Immun (1998) 1.74

Modulation of host immune responses, induction of apoptosis and inhibition of NF-kappaB activation by the Bordetella type III secretion system. Mol Microbiol (2000) 1.73

Autogenous regulation of the Bordetella pertussis bvgABC operon. Proc Natl Acad Sci U S A (1990) 1.72

Postoperative cognitive deficit in the elderly surgical patient. Br J Anaesth (1998) 1.72

Species- and strain-specific control of a complex, flexible regulon by Bordetella BvgAS. J Bacteriol (2006) 1.70

Induction of autoimmune diabetes by oral administration of autoantigen. Science (1996) 1.69

Comparative analysis of the virulence control systems of Bordetella pertussis and Bordetella bronchiseptica. Mol Microbiol (1996) 1.69

Interaction of thymus lymphocytes with histoincompatible cells. I. Quantitation of the proliferative response of thymus cells. Cell Immunol (1972) 1.68

The immunological responsiveness of germ-free mice thymectomized at birth. I. Antibody production and skin homograft rejection. Clin Exp Immunol (1967) 1.66

Autophosphorylation and phosphotransfer in the Bordetella pertussis BvgAS signal transduction cascade. Proc Natl Acad Sci U S A (1994) 1.65

In vivo studies of DnaA binding to the origin of replication of Escherichia coli. EMBO J (1989) 1.60

Effect of recent antigen priming on adoptive immune responses. I. Specific unresponsiveness of cells from lymphoid organs of mice primed with heterologous erythrocytes. J Exp Med (1973) 1.58

Relationship between Fc receptors, antigen-binding sites on T and B cells, and H-2 complex-associated determinants. J Exp Med (1975) 1.58

Dietary and other characteristics relevant for coronary heart disease in men of Indian, West Indian and European descent in London. Atherosclerosis (1988) 1.58

Mice lacking the orphan G protein-coupled receptor G2A develop a late-onset autoimmune syndrome. Immunity (2001) 1.58

CD8 T cell ignorance or tolerance to islet antigens depends on antigen dose. Proc Natl Acad Sci U S A (1999) 1.55

Cell to cell interaction in the immune response. V. Target cells for tolerance induction. J Exp Med (1970) 1.55