Published in J Exp Med on October 01, 1968
An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity. J Exp Med (1970) 9.83
Cell to cell interaction in the immune response. I. Hemolysin-forming cells in neonatally thymectomized mice reconstituted with thymus or thoracic duct lymphocytes. J Exp Med (1968) 9.67
Two distinct populations of peripheral lymphocytes in mice distinguishable by immunofluorescence. Immunology (1970) 7.10
Cell interactions in the induction of tolerance: the role of thymic lymphocytes. Immunology (1970) 6.06
Cell surface immunoglobulin. II. Isolation and characterization of immunoglobulin from mouse splenic lymphocytes. J Exp Med (1971) 5.80
Carrier function in anti-hapten immune responses. I. Enhancement of primary and secondary anti-hapten antibody responses by carrier preimmunization. J Exp Med (1970) 5.71
The requirement of more than one antigenic determinant for immunogenicity. J Exp Med (1969) 5.61
Immunoglobulins on the surface of lymphocytes. II. The bone marrow as the main source of lymphocytes with detectable surface-bound immunoglobulin. J Exp Med (1971) 5.43
Critical role of determinant presentation in the induction of specific responses in immunocompetent lymphocytes. J Exp Med (1973) 5.30
Cell to cell interaction in the immune response. 3. Chromosomal marker analysis of single antibody-forming cells in reconstituted, irradiated, or thymectomized mice. J Exp Med (1968) 5.02
Synergy among lymphoid cells mediating the graft-versus-host response. II. Synergy in graft-versus-host reactions produced by Balb-c lymphoid cells of differing anatomic origin. J Exp Med (1970) 4.14
B lymphocytes: how they develop and function. Blood (2008) 4.07
Thymus dependence of theta-bearing cells in the peripheral lymphoid tissues of mice. Immunology (1970) 3.84
Synergy among lymphoid cells mediating the graft-versus-host response. 3. Evidence for interaction between two types of thymus-derived cells. J Exp Med (1972) 3.77
Identification of marrow-derived and thymus-derived small lymphocytes in the lymphoid tissue and thoracic duct lymph of normal rats. J Exp Med (1972) 3.54
Immunoglobulin and other surface antigens of cells of the immune system. J Exp Med (1971) 3.50
The life-span and recirculation of marrow-derived small lymphocytes from the rat thoracic duct. J Exp Med (1972) 3.42
Cell to cell interaction in the immune response. IV. Site of action of antilymphocyte globulin. J Exp Med (1968) 3.16
Cell-to-cell interaction in the immune response. VI. Contribution of thymus-derived cells and antibody-forming cell precursors to immunological memory. J Exp Med (1971) 3.14
Cellular sites of immunologic unresponsiveness. Proc Natl Acad Sci U S A (1970) 3.01
Cells mediating specific in vitro cytotoxicity. II. Probable autonomy of thymus-processed lymphocytes (T cells) for the killing of allogeneic target cells. J Exp Med (1972) 3.00
The role of nonlymphoid accessory cells in the immune response to different antigens. J Exp Med (1970) 2.82
Evolutionarily conserved amino acids that control TCR-MHC interaction. Annu Rev Immunol (2008) 2.79
Radioresistance of the enhancing effect of cells from carrier-immunized mice in an in vitro primary immune response. Proc Natl Acad Sci U S A (1971) 2.79
Characterization of splenic lymphoid cells in fetal and newborn mice. J Exp Med (1973) 2.75
Characterization of the antibody response to type 3 pneumococcal polysaccharide at the cellular level. I. Dose-response studies and the effect of prior immunization on the magnitude of the antibody response. Immunology (1971) 2.74
Lymphoid tissue architecture. Experimental analysis of the origin and distribution of T-cells and B-cells. Immunology (1972) 2.65
Studies on the differentiation of thymus-derived lymphocytes. J Exp Med (1970) 2.56
Carrier function in anti-hapten immune responses. II. Specific properties of carrier cells capable of enhancing anti-hapten antibody responses. J Exp Med (1970) 2.54
Induction of a hemolysin response in vitro. Interaction of cells of bone marrow origin and thymic origin. J Exp Med (1970) 2.49
Induction and recall in contact sensivitity. Changes in skin and draining lymph nodes of intact and thymectomized mice. J Exp Med (1969) 2.27
Antibody-mediated suppression of the immune response in vitro. I. Evidence for a central effect. J Exp Med (1970) 2.17
Termination of tolerance to human gamma globulin in mice by antigen and bacterial lipopolysaccharide (endotoxin). J Exp Med (1973) 2.15
Synergy among lymphoid cells mediating the graft-versus-host response. I. Synergy in graft-versus-host reactions produced by cells from NZB-Bl mice. J Exp Med (1970) 2.15
Genetic control of the antibody response to poly-L(Tyr,Glu)-poly-D,L-Ala--poly-L-Lys in C3H--CWB tetraparental mice. J Exp Med (1974) 2.14
In vitro cytotoxicity by a nonthymus-processed lymphocyte population with specificity for a virally determined tumor cell surface antigen. J Exp Med (1972) 2.13
Identification of a novel surface protein on activated CD4+ T cells that induces contact-dependent B cell differentiation (help). J Exp Med (1992) 2.03
The effect of inoculum size on the immune response to BCG infection in mice. Immunology (1971) 1.96
Cell cooperation in the immune response. Clin Exp Immunol (1971) 1.91
Antigen-reactive cells in normal, immunized, and tolerant mice. J Exp Med (1969) 1.89
Studies on immunological paralysis. IX. The immunogenicity and tolerogenicity of levan (polyfructose) in mice. Immunology (1972) 1.84
Monospecificity of bone marrow-derived lymphocytes. J Exp Med (1973) 1.74
Distinct events in the immune response elicited by transferred marrow and thymus cells. I. Antigen requirements and priferation of thymic antigen-reactive cells. J Exp Med (1969) 1.72
Regulation of antibody response by cells expressing histamine receptors. J Exp Med (1972) 1.70
Selective priming of T cells by chemically altered cell antigens. J Exp Med (1972) 1.69
A quantitative assay for the progenitors of bone marrow-associated lymphocytes. J Exp Med (1972) 1.69
The lymphocyte response to primary Moloney sarcoma virus tumors in BALB-c mice. Definition of the active subpopulations at different times after infection. J Exp Med (1973) 1.68
Antibody and immunoglobulin production at the cellular level in bursectomized-irradiated chickens. J Exp Med (1969) 1.66
Surface antigens of immunocompetent cells. I. Effect of theta and PC.1 alloantisera on the ability of spleen cells to transfer immune responses. J Exp Med (1970) 1.65
Regulation of the immune system by synthetic polynucleotides. 3. Action on antigen-reactive cells of thymic origin. J Exp Med (1971) 1.63
The functional dissection of an antigen molecule: specificity of humoral and cellular immune responses to glucagon. J Exp Med (1971) 1.62
Immunological memory in mice. I. Physical separation and partial characterization of memory cells for different immunoglobulin classes from each other and from antibody-producing cells. J Exp Med (1970) 1.57
Splenic Dendritic Cells Survey Red Blood Cells for Missing Self-CD47 to Trigger Adaptive Immune Responses. Immunity (2015) 1.56
The effect of pertussis vaccine on the immune response of mice to sheep red blood cells. Clin Exp Immunol (1970) 1.56
Cell to cell interaction in the immune response. V. Target cells for tolerance induction. J Exp Med (1970) 1.55
A two-stage model for development of antibody-producing cells. Clin Exp Immunol (1972) 1.53
Thymus-independence of slowly metabolized immunogens. Proc Natl Acad Sci U S A (1972) 1.52
Cellular differentiation of the immune system of mice. V. Class differentiation in marrow precursors of plaque-forming cells. J Exp Med (1969) 1.50
The ability of bacterial lipopolysaccharide to modulate the induction of unresponsiveness to a state of immunity. Cellular parameters. J Exp Med (1973) 1.49
Cells involved in the immune response. VI. The immune response to red blood cells in irradiated rabbits after administration of normal, primed, or immune allogeneic rabbit bone marrow cells. J Exp Med (1969) 1.48
Cell-to-cell interaction in the immune response. VII. Requirement for differentiation of thymus-derived cells. J Exp Med (1971) 1.46
Function and distribution pattern of human T lymphocytes. I. Production of anti-T lymphocyte specific sera as estimated by cytotoxicity and elimination of function of lymphocytes. Clin Exp Immunol (1973) 1.46
Immunoglobulin synthesis and secretion. VI. Synthesis and intracellular transport of immunoglobulin in nonsecretory lymphoma cells. J Exp Med (1971) 1.45
Immune responses against native and chemically modified albumins in mice. I. Analysis of non-thymus-processed (B) and thymus-processed (T) cell responses against methylated bovine serum albumin. J Exp Med (1972) 1.45
The abrogation of sheep erythrocyte tolerance in rats by means of the transfer of allogeneic lymphocytes. J Exp Med (1970) 1.43
Immunological memory in mice. II. Cell interactions in the secondary immune response studies by means of immunoglobulin allotype markers. J Exp Med (1970) 1.42
On the number and nature of antigen-sensitive lymphocytes in the blood of delayed-hypersensitive human donors. J Exp Med (1971) 1.42
Helper and killer T cells do not express B cell immunoglobulin joining and constant region gene segments. J Exp Med (1980) 1.42
Synergism of thymus and bone marrow in the production of gra a5hilgard HR: Synergism of thymus and bone marrow in the production of graft-versus-host splenomegaly in x-irradiated hosts. J Exp Med (1970) 1.42
The activation and inactivation of mature CD4 T cells: a case for peripheral self-nonself discrimination. Scand J Immunol (2014) 1.41
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Specific heterologous enhancement of immune responses. Proc Natl Acad Sci U S A (1971) 1.37
Peritoneal macrophages in the immune response to SRBC in vitro. Immunology (1970) 1.35
Studies on the cellular basis of IgM immunological memory. The induction of antibody formation in bone marrow cells by primed spleen cells. Immunology (1969) 1.34
Germinal centres and the origin of the B-cell system. II. Germinal centres in the rabbit spleen and popliteal lymph nodes. Immunology (1974) 1.32
Cellular differentiation of the immune system of mice. IV. Lack of class differentiation in thymic antigen-reactive cells. J Exp Med (1969) 1.31
Antibody formation by bone marrow cells in irradiated mice. I. Thymus-dependent and thymus-independent responses to sheep erythrocytes. Immunology (1971) 1.31
Density distribution analysis of antigen-sensitive cells in the rat. J Exp Med (1969) 1.30
Lymphocyte activation. IV. The ultrastructural pattern of the response of mouse T and B cells to mitogenic stimulation in vitro. Immunology (1973) 1.29
Regulation of the immune response. V. An analysis of the function of the Fc portion of antibody in suppression of an immune response with respect to interaction with components of the lymphoid system. Immunology (1971) 1.24
The termination of immunological unresponsiveness to bovine serum albumin in rabbits. I. Quantitative and qualitative response to cross-reacting albumins. J Exp Med (1970) 1.24
Cellular differentiation of the immune system of mice. 3. Separate antigen-sensitive units for different types of anti-sheep immunocytes formed by marrow-thymus cell mixtures. J Exp Med (1969) 1.23
Transfer of antibody production with cells from bursa of Fabricius. J Exp Med (1970) 1.23
Quantitative studies on the proliferation and differentiation of antibody-forming cells in lymph. Am J Pathol (1972) 1.22
Surface markers on lymphocytes of patients with infectious diseases. Infect Immun (1973) 1.21
A brief history of T cell help to B cells. Nat Rev Immunol (2015) 1.21
The structural basis of αβ T-lineage immune recognition: TCR docking topologies, mechanotransduction, and co-receptor function. Immunol Rev (2012) 1.20
Development of chicken lymphoid system. I. Synthesis and secretion of immunoglobulins by chicken lymphoid cells. J Exp Med (1972) 1.20
Antigen-binding thymus-derived lymphocytes. II. Nature of the immunoglobulin determinants. Immunology (1972) 1.18
In vitro-initiated secondary anti-hapten response. II. Increasing cell avidity for antigen. J Exp Med (1970) 1.18
The chemical nature of macrophage RNA-antigen complexes and their relevance to immune induction. J Exp Med (1969) 1.16
Thymus independence of a collagen-like synthetic polypeptide and of collagen, and the need for thymus and bone marrow-cell cooperation in the immune response to gelatin. J Exp Med (1974) 1.15
Thymus-marrow cell combinations. Synergism in antibody production. Proc Soc Exp Biol Med (1966) 10.03
Cell to cell interaction in the immune response. I. Hemolysin-forming cells in neonatally thymectomized mice reconstituted with thymus or thoracic duct lymphocytes. J Exp Med (1968) 9.67
Thymus-dependent areas in the lymphoid organs of neonatally thymectomized mice. J Exp Med (1966) 8.61
Current concepts of the immunological function of the thymus. Physiol Rev (1967) 8.37
The mitotic response of thymus-derived cells to antigenic stimulus. Transplantation (1966) 8.14
Immunological activity of thymus and thoracic-duct lymphocytes. Proc Natl Acad Sci U S A (1968) 7.49
Cell to cell interaction in the immune response. 3. Chromosomal marker analysis of single antibody-forming cells in reconstituted, irradiated, or thymectomized mice. J Exp Med (1968) 5.02
The thymus and the precursors of antigen reactive cells. Nature (1967) 3.92
Regeneration of thymus grafts. I. Histological and cytological aspects. Transplantation (1965) 3.29
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Prevention of bone marrow heterografting. Use of isologous thymus in lethally irradiated mice. Arch Pathol (1961) 1.72
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Cell to cell interaction in the immune response. I. Hemolysin-forming cells in neonatally thymectomized mice reconstituted with thymus or thoracic duct lymphocytes. J Exp Med (1968) 9.67
Thymus and antigen-reactive cells. Transplant Rev (1969) 8.84
Current concepts of the immunological function of the thymus. Physiol Rev (1967) 8.37
Immunological activity of thymus and thoracic-duct lymphocytes. Proc Natl Acad Sci U S A (1968) 7.49
A receptor for antibody on B lymphocytes. I. Method of detection and functional significance. J Exp Med (1972) 7.47
Class I-restricted cross-presentation of exogenous self-antigens leads to deletion of autoreactive CD8(+) T cells. J Exp Med (1997) 5.72
Constitutive class I-restricted exogenous presentation of self antigens in vivo. J Exp Med (1996) 5.21
Cell to cell interaction in the immune response. 3. Chromosomal marker analysis of single antibody-forming cells in reconstituted, irradiated, or thymectomized mice. J Exp Med (1968) 5.02
Sequences required for expression of Bordetella pertussis virulence factors share homology with prokaryotic signal transduction proteins. Proc Natl Acad Sci U S A (1989) 4.78
Specific inactivation of thymus-derived (T) and non-thymus-derived (B) lymphocytes by 125I-labelled antigen. Nat New Biol (1971) 4.55
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Induction of a CD8+ cytotoxic T lymphocyte response by cross-priming requires cognate CD4+ T cell help. J Exp Med (1997) 4.01
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Cellular basis of the immunological defects in thymectomized mice. Nature (1967) 3.69
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BvgAS-mediated signal transduction: analysis of phase-locked regulatory mutants of Bordetella bronchiseptica in a rabbit model. Infect Immun (1994) 3.44
Antigen-induced selective recruitment of circulating lymphocytes. Cell Immunol (1971) 3.35
H-2 gene complex restricts transfer of delayed-type hypersensitivity in mice. Proc Natl Acad Sci U S A (1975) 3.34
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Antigen-induced arthritis in mice. I. Induction of arthritis in various strains of mice. Arthritis Rheum (1977) 3.23
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Cell to cell interaction in the immune response. IV. Site of action of antilymphocyte globulin. J Exp Med (1968) 3.16
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T cell-dependent suppression of an anti-hapten antibody response. Transplant Rev (1975) 3.06
Genetic control of the immune response. The effect of thymectomy on the primary and secondary antibody response of mice to poly-L(tyr, glu)-poly-D, L-ala--poly-L-lys. J Exp Med (1972) 3.06
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Ly and Ia antigen phenotypes of T cells involved in delayed-type hypersensitivity and in suppression. J Exp Med (1976) 3.00
Early embryonic mortality in women. Fertil Steril (1982) 2.92
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Integration of multiple domains in a two-component sensor protein: the Bordetella pertussis BvgAS phosphorelay. EMBO J (1996) 2.41
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Histocompatibility-linked genetic control of disease susceptibility. Murine lymphocytic choriomeningitis virus infection. J Exp Med (1973) 2.39
Mr 26,000 antigen of Schistosoma japonicum recognized by resistant WEHI 129/J mice is a parasite glutathione S-transferase. Proc Natl Acad Sci U S A (1986) 2.35
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Inhibition of secondary anti-hapten responses with the hapten conjugated to type 3 pneumococcal polysaccharide. Eur J Immunol (1972) 2.14
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