Association of physical activity with lower type 2 diabetes incidence is weaker among individuals at high genetic risk.

PubWeight™: 0.90‹?›

🔗 View Article (PMID 25273344)

Published in Diabetologia on October 02, 2014

Authors

Yann C Klimentidis1, Zhao Chen, Amit Arora, Chiu-Hsieh Hsu

Author Affiliations

1: Mel and Enid Zuckerman College of Public Health, Division of Epidemiology and Biostatistics, University of Arizona, 1295 N. Martin, Tucson, AZ, 85724, USA, yann@email.arizona.edu.

Articles cited by this

The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. The ARIC investigators. Am J Epidemiol (1989) 37.83

A short questionnaire for the measurement of habitual physical activity in epidemiological studies. Am J Clin Nutr (1982) 17.28

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09

Genotype imputation with thousands of genomes. G3 (Bethesda) (2011) 8.77

Low-grade systemic inflammation and the development of type 2 diabetes: the atherosclerosis risk in communities study. Diabetes (2003) 5.43

Neighbourhood differences in diet: the Atherosclerosis Risk in Communities (ARIC) Study. J Epidemiol Community Health (1999) 5.07

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73

Physical activity/exercise and type 2 diabetes: a consensus statement from the American Diabetes Association. Diabetes Care (2006) 4.52

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med (2011) 3.94

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. Diabetes (2013) 2.70

Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: where are the insulin resistance genes? Diabetologia (2008) 2.65

Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study. PLoS Med (2010) 2.25

Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study. PLoS Med (2014) 2.22

Physical activity and incidence of coronary heart disease in middle-aged women and men. Med Sci Sports Exerc (1997) 1.94

Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry. PLoS Genet (2013) 1.51

Effect of exercise training on insulin sensitivity and glucose metabolism in lean, obese, and diabetic men. J Appl Physiol (1985) (1991) 1.06

Association of the peroxisome proliferator-activated receptor gamma gene with type 2 diabetes mellitus varies by physical activity among non-Hispanic whites from Colorado. Metabolism (2007) 1.04

Previously associated type 2 diabetes variants may interact with physical activity to modify the risk of impaired glucose regulation and type 2 diabetes: a study of 16,003 Swedish adults. Diabetes (2009) 0.99

Physical activity modifies the effect of SNPs in the SLC2A2 (GLUT2) and ABCC8 (SUR1) genes on the risk of developing type 2 diabetes. Physiol Genomics (2007) 0.90

Articles by these authors

(truncated to the top 100)

Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate. Cancer Cell (2006) 10.10

Ethnicity and breast cancer: factors influencing differences in incidence and outcome. J Natl Cancer Inst (2005) 5.52

Dynamic visualization of thrombopoiesis within bone marrow. Science (2007) 4.35

Effects of estrogen plus progestin on risk of fracture and bone mineral density: the Women's Health Initiative randomized trial. JAMA (2003) 4.07

Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition. Proc Natl Acad Sci U S A (2009) 4.02

Proton pump inhibitor use, hip fracture, and change in bone mineral density in postmenopausal women: results from the Women's Health Initiative. Arch Intern Med (2010) 3.53

Oral bisphosphonate use and breast cancer incidence in postmenopausal women. J Clin Oncol (2010) 3.17

Calcium plus vitamin D supplementation and health outcomes five years after active intervention ended: the Women's Health Initiative. J Womens Health (Larchmt) (2013) 2.81

Factors associated with 5-year risk of hip fracture in postmenopausal women. JAMA (2007) 2.81

Matrix-assisted laser desorption ionization-time of flight mass spectrometry: a fundamental shift in the routine practice of clinical microbiology. Clin Microbiol Rev (2013) 2.34

Receptor tyrosine kinases exert dominant control over PI3K signaling in human KRAS mutant colorectal cancers. J Clin Invest (2011) 2.20

PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis. Nat Genet (2007) 2.18

Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism. Blood (2008) 1.86

Statin use, clinical fracture, and bone density in postmenopausal women: results from the Women's Health Initiative Observational Study. Ann Intern Med (2003) 1.81

Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). PLoS Genet (2011) 1.75

Hip fractures and heart failure: findings from the Cardiovascular Health Study. Eur Heart J (2009) 1.72

K-ras(G12V) transformation leads to mitochondrial dysfunction and a metabolic switch from oxidative phosphorylation to glycolysis. Cell Res (2011) 1.72

Does obesity really make the femur stronger? BMD, geometry, and fracture incidence in the women's health initiative-observational study. J Bone Miner Res (2009) 1.71

Nutrient intake and anemia risk in the women's health initiative observational study. J Am Diet Assoc (2011) 1.60

Magnesium intake, bone mineral density, and fractures: results from the Women's Health Initiative Observational Study. Am J Clin Nutr (2014) 1.60

Imputation of exome sequence variants into population- based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing Project. Am J Hum Genet (2012) 1.60

Efficacy of BET bromodomain inhibition in Kras-mutant non-small cell lung cancer. Clin Cancer Res (2013) 1.56

Clinical risk factors for fractures in multi-ethnic women: the Women's Health Initiative. J Bone Miner Res (2007) 1.56

Effect of hormone therapy on lean body mass, falls, and fractures: 6-year results from the Women's Health Initiative hormone trials. Menopause (2011) 1.56

Performance evaluation of a multiplex assay for future use in biomarker discovery efforts to predict body composition. Clin Chem Lab Med (2011) 1.48

Metabolic alterations in highly tumorigenic glioblastoma cells: preference for hypoxia and high dependency on glycolysis. J Biol Chem (2011) 1.48

Ethnic and geographic differences in mammographic density and their association with breast cancer incidence. Breast Cancer Res Treat (2006) 1.46

Effects of self-reported age at nonsurgical menopause on time to first fracture and bone mineral density in the Women's Health Initiative Observational Study. Menopause (2015) 1.45

Mitochondrial dysfunction and reactive oxygen species imbalance promote breast cancer cell motility through a CXCL14-mediated mechanism. Cancer Res (2009) 1.42

Bone mineral density of American Indian and Alaska Native women compared with non-Hispanic white women: results from the Women's Health Initiative Study. Menopause (2005) 1.40

The prevalence of bedrail use in British hospitals. Age Ageing (2003) 1.39

Invasive snails and an emerging infectious disease: results from the first national survey on Angiostrongylus cantonensis in China. PLoS Negl Trop Dis (2009) 1.38

Bayesian spatio-temporal modeling of Schistosoma japonicum prevalence data in the absence of a diagnostic 'gold' standard. PLoS Negl Trop Dis (2008) 1.38

Handling missing data in RCTs; a review of the top medical journals. BMC Med Res Methodol (2014) 1.35

Race and ethnicity and breast cancer outcomes in an underinsured population. J Natl Cancer Inst (2010) 1.33

Test-retest reliability of a sexual behavior interview for men residing in Brazil, Mexico, and the United States: the HPV in Men (HIM) Study. Am J Epidemiol (2009) 1.33

Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer. Cancer Discov (2013) 1.27

Quadfinder: server for identification and analysis of quadruplex-forming motifs in nucleotide sequences. Nucleic Acids Res (2006) 1.26

Phacoemulsification induced transient swelling of corneal Descemet's Endothelium Complex imaged with ultra-high resolution optical coherence tomography. PLoS One (2013) 1.26

Subclinical thyroid dysfunction and incident hip fracture in older adults. Arch Intern Med (2010) 1.19

Thermodynamic, counterion, and hydration effects for the incorporation of locked nucleic acid nucleotides into DNA duplexes. Biochemistry (2006) 1.17

Relationship of total body fat mass to weight-bearing bone volumetric density, geometry, and strength in young girls. Bone (2010) 1.15

Diagnostic testing for IDH1 and IDH2 variants in acute myeloid leukemia an algorithmic approach using high-resolution melting curve analysis. J Mol Diagn (2011) 1.15

Novel role of NOX in supporting aerobic glycolysis in cancer cells with mitochondrial dysfunction and as a potential target for cancer therapy. PLoS Biol (2012) 1.14

Resveratrol modulates drug- and carcinogen-metabolizing enzymes in a healthy volunteer study. Cancer Prev Res (Phila) (2010) 1.13

Association between body mass index and arsenic methylation efficiency in adult women from southwest U.S. and northwest Mexico. Toxicol Appl Pharmacol (2011) 1.13

Lysine-specific demethylase 2B (KDM2B)-let-7-enhancer of zester homolog 2 (EZH2) pathway regulates cell cycle progression and senescence in primary cells. J Biol Chem (2011) 1.12

[Schistosomiasis status in People's Republic of China in 2010]. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi (2011) 1.12

Mineral metabolism markers and the long-term risk of hip fracture: the cardiovascular health study. J Clin Endocrinol Metab (2011) 1.12

Pilot study of dietary influences on mammographic density in pre- and postmenopausal Hispanic and non-Hispanic white women. Menopause (2007) 1.11

Molecular crowding creates an essential environment for the formation of stable G-quadruplexes in long double-stranded DNA. Nucleic Acids Res (2009) 1.10

G-quadruplex formation at the 3' end of telomere DNA inhibits its extension by telomerase, polymerase and unwinding by helicase. Nucleic Acids Res (2011) 1.09

[The current status of schistosomiasis epidemics in China]. Zhonghua Liu Xing Bing Xue Za Zhi (2004) 1.09

Predicting enhancer transcription and activity from chromatin modifications. Nucleic Acids Res (2013) 1.08

Replication of loci influencing ages at menarche and menopause in Hispanic women: the Women's Health Initiative SHARe Study. Hum Mol Genet (2011) 1.07

Depression, antidepressants, and bone health in older adults: a systematic review. J Am Geriatr Soc (2015) 1.07

Skeletal muscle fat content is inversely associated with bone strength in young girls. J Bone Miner Res (2011) 1.06

Effect of aspirin, other NSAIDs, and statins on PSA and PSA velocity. Prostate (2010) 1.06

Potential solution processible phosphorescent iridium complexes toward applications in doped light-emitting diodes: rapid syntheses and optical and morphological characterizations. J Org Chem (2006) 1.06

Effects of repeated green tea catechin administration on human cytochrome P450 activity. Cancer Epidemiol Biomarkers Prev (2006) 1.05

Arthritis increases the risk for fractures--results from the Women's Health Initiative. J Rheumatol (2011) 1.05

Randomized, double-blind, placebo-controlled trial of polyphenon E in prostate cancer patients before prostatectomy: evaluation of potential chemopreventive activities. Cancer Prev Res (Phila) (2011) 1.02

[The first national survey on natural nidi of Angiostrongylus cantonensis in China]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi (2009) 1.00

Official Positions for FRAX® clinical regarding international differences from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX®. J Clin Densitom (2011) 0.97

Doubly Robust Nonparametric Multiple Imputation for Ignorable Missing Data. Stat Sin (2012) 0.96

Fiber, sex, and colorectal adenoma: results of a pooled analysis. Am J Clin Nutr (2006) 0.95

Novel role of resveratrol: suppression of high-mobility group protein box 1 nucleocytoplasmic translocation by the upregulation of sirtuin 1 in sepsis-induced liver injury. Shock (2014) 0.94

IGF-I and mammographic density in four geographic locations: a pooled analysis. Int J Cancer (2007) 0.94

Associations of Ki-ras proto-oncogene mutation and p53 gene overexpression in sporadic colorectal adenomas with demographic and clinicopathologic characteristics. Cancer Epidemiol Biomarkers Prev (2006) 0.94

Inhibition of mitochondrial respiration and rapid depletion of mitochondrial glutathione by β-phenethyl isothiocyanate: mechanisms for anti-leukemia activity. Antioxid Redox Signal (2011) 0.94

Comparative effectiveness of sphincter-sparing surgery versus abdominoperineal resection in rectal cancer: patient-reported outcomes in National Surgical Adjuvant Breast and Bowel Project randomized trial R-04. Ann Surg (2015) 0.94

Vitamin A and retinol intakes and the risk of fractures among participants of the Women's Health Initiative Observational Study. Am J Clin Nutr (2008) 0.93

The antitumor thioredoxin-1 inhibitor PX-12 (1-methylpropyl 2-imidazolyl disulfide) decreases thioredoxin-1 and VEGF levels in cancer patient plasma. J Lab Clin Med (2006) 0.93

Comparative study on polymer light-emitting devices based on blends of polyfluorene and 4,7-di-2-thienyl-2,1,3-benzothiadiazole with devices based on copolymer of the same composition. J Phys Chem B (2007) 0.93

HSulf-1 inhibits cell proliferation and invasion in human gastric cancer. Cancer Sci (2011) 0.92

Transcatheter patent foramen ovale closure versus medical therapy for cryptogenic stroke: a meta-analysis of randomized clinical trials. BMC Cardiovasc Disord (2013) 0.92

Metabolically active portion of fat-free mass: a cellular body composition level modeling analysis. Am J Physiol Endocrinol Metab (2006) 0.92

Oral selenium supplementation has no effect on prostate-specific antigen velocity in men undergoing active surveillance for localized prostate cancer. Cancer Prev Res (Phila) (2010) 0.92

Sodium valproate alleviates neurodegeneration in SCA3/MJD via suppressing apoptosis and rescuing the hypoacetylation levels of histone H3 and H4. PLoS One (2013) 0.91

Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons. Cell Metab (2007) 0.91

RMRP is a non-coding RNA essential for early murine development. PLoS One (2011) 0.91

Associations between mammographic density and body composition in Hispanic and non-Hispanic white women by menopause status. Menopause (2008) 0.91

Biomarker-calibrated protein intake and physical function in the Women's Health Initiative. J Am Geriatr Soc (2013) 0.90

Simple subtyping assay for human immunodeficiency virus type 1 subtypes B, C, CRF01-AE, CRF07-BC, and CRF08-BC. J Clin Microbiol (2004) 0.90

Expression of gastric pyloric mucin, MUC6, in colorectal serrated polyps. Mod Pathol (2009) 0.89

High-level expression, purification, and characterization of non-tagged Aspergillus flavus urate oxidase in Escherichia coli. Protein Expr Purif (2006) 0.89

Measured versus modeled dietary arsenic and relation to urinary arsenic excretion and total exposure. J Expo Sci Environ Epidemiol (2013) 0.89

Short sleep duration is associated with decreased serum leptin, increased energy intake and decreased diet quality in postmenopausal women. Obesity (Silver Spring) (2014) 0.88

Association of health literacy with adherence to screening mammography guidelines. Obstet Gynecol (2015) 0.88

Changes in physical activity and body composition in postmenopausal women over time. Med Sci Sports Exerc (2013) 0.88

Estimation of percentage body fat by dual-energy x-ray absorptiometry: evaluation by in vivo human elemental composition. Phys Med Biol (2010) 0.87

Somatization is associated with deficits in affective Theory of Mind. J Psychosom Res (2013) 0.87

Acute myeloid leukemia (AML) with erythroid predominance exhibits clinical and molecular characteristics that differ from other types of AML. PLoS One (2012) 0.87

Human breast tissue disposition and bioactivity of limonene in women with early-stage breast cancer. Cancer Prev Res (Phila) (2013) 0.86

Indigenous American ancestry is associated with arsenic methylation efficiency in an admixed population of northwest Mexico. J Toxicol Environ Health A (2012) 0.86

The combination of the novel glycolysis inhibitor 3-BrOP and rapamycin is effective against neuroblastoma. Invest New Drugs (2010) 0.86

Evidence for common machinery utilized by the early and late RNA localization pathways in Xenopus oocytes. Dev Biol (2005) 0.86

Salvianolic acid A preconditioning confers protection against concanavalin A-induced liver injury through SIRT1-mediated repression of p66shc in mice. Toxicol Appl Pharmacol (2013) 0.86

Iron deficiency anemia in women across the life span. J Womens Health (Larchmt) (2012) 0.86

Intraoperative ultrasound can decrease the re-excision lumpectomy rate in patients with palpable breast cancers. Am Surg (2011) 0.86