Published in PLoS One on October 17, 2014
Colorectal cancer statistics, 2014. CA Cancer J Clin (2014) 12.86
Insulin, insulin-like growth factors and colon cancer: a review of the evidence. J Nutr (2001) 5.16
Diabetes and cancer. Endocr Relat Cancer (2009) 5.04
Colorectal cancer: molecules and populations. J Natl Cancer Inst (1999) 4.39
Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening. Pharmacol Res (2005) 3.96
Insulin therapy and colorectal cancer risk among type 2 diabetes mellitus patients. Gastroenterology (2004) 3.57
Insulin and colon cancer. Cancer Causes Control (1995) 3.48
Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: preliminary findings. Cancer Lett (1987) 3.41
High aerobic glycolysis of rat hepatoma cells in culture: role of mitochondrial hexokinase. Proc Natl Acad Sci U S A (1977) 2.20
Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation. Proc Natl Acad Sci U S A (2012) 2.10
Role of aberrant crypt foci in understanding the pathogenesis of colon cancer. Cancer Lett (1995) 1.85
On respiratory impairment in cancer cells. Science (1956) 1.82
Possible mechanisms relating diet and risk of colon cancer. Cancer Epidemiol Biomarkers Prev (2000) 1.60
Diabetes mellitus and the incidence of colorectal cancer: an updated systematic review and meta-analysis. Dig Dis Sci (2012) 1.56
An imbalance between glycolysis and glucose oxidation is a possible explanation for the detrimental effects of high levels of fatty acids during aerobic reperfusion of ischemic hearts. J Pharmacol Exp Ther (1993) 1.32
Mechanisms linking diet and colorectal cancer: the possible role of insulin resistance. Nutr Cancer (2000) 1.30
Treatment of mitochondrial electron transport chain disorders: a review of clinical trials over the past decade. Mol Genet Metab (2009) 1.28
Glucose phosphorylation in tumor cells. Cloning, sequencing, and overexpression in active form of a full-length cDNA encoding a mitochondrial bindable form of hexokinase. J Biol Chem (1990) 1.20
Sequential analyses of the growth and morphological characteristics of aberrant crypt foci: putative preneoplastic lesions. Cancer Res (1991) 1.17
The relation of type 2 diabetes and cancer. Diabetes Technol Ther (2001) 1.16
Type 2 diabetes mellitus as risk factor for colorectal cancer. Arch Physiol Biochem (2008) 1.15
Insulin-insulin-like growth factor axis and colon cancer. J Clin Oncol (2008) 1.12
Insulin resistance, hyperinsulinemia, hypertriglyceridemia, and hypertension. Parallels between human disease and rodent models. Diabetes Care (1991) 1.07
Reversal of glucose intolerance by by pioglitazone in high fat diet-fed rats. Methods Find Exp Clin Pharmacol (2004) 1.06
Analysis of the signaling pathway involved in the regulation of hexokinase II gene transcription by insulin. J Biol Chem (1996) 1.05
Hyperinsulinaemia and hyperglycaemia: possible risk factors of colorectal cancer among diabetic patients. Diabetologia (2003) 1.04
Nutrient deprivation induces the Warburg effect through ROS/AMPK-dependent activation of pyruvate dehydrogenase kinase. Biochim Biophys Acta (2013) 1.03
Cardiac metabolism in a new rat model of type 2 diabetes using high-fat diet with low dose streptozotocin. Cardiovasc Diabetol (2013) 1.00
Methodological findings and considerations in measuring colorectal epithelial cell proliferation in humans. Cancer Epidemiol Biomarkers Prev (1997) 0.98
Combination of curcumin and green tea catechins prevents dimethylhydrazine-induced colon carcinogenesis. Food Chem Toxicol (2009) 0.96
Role of metformin in suppressing 1,2-dimethylhydrazine-induced colon cancer in diabetic and non-diabetic mice: effect on tumor angiogenesis and cell proliferation. PLoS One (2014) 0.91
Insulin therapy and colorectal adenomas in patients with diabetes mellitus. Cancer Epidemiol Biomarkers Prev (2012) 0.88
Aberrant crypt foci and colon cancer: comparison between a short- and medium-term bioassay for colon carcinogenesis using dimethylhydrazine in Wistar rats. Braz J Med Biol Res (2002) 0.88
Aberrant crypt foci in the colonic mucosa of rats treated with a genotoxic and nongenotoxic colon carcinogen. Toxicol Pathol (1997) 0.86
Possible therapeutic targets among the molecules involved in the Warburg effect in tumor cells. Anticancer Res (2013) 0.83
cDNA, genomic sequence cloning and overexpression of ribosomal protein gene L9 (rpL9) of the giant panda (Ailuropoda melanoleuca). Genet Mol Res (2011) 0.82