Published in Thyroid on January 01, 2015
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How one TSH receptor antibody induces thyrocyte proliferation while another induces apoptosis. J Autoimmun (2013) 0.87
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A selective TSH receptor antagonist inhibits stimulation of thyroid function in female mice. Endocrinology (2013) 0.86
Extended and structurally supported insights into extracellular hormone binding, signal transduction and organization of the thyrotropin receptor. PLoS One (2012) 0.86
From molecular details of the interplay between transmembrane helices of the thyrotropin receptor to general aspects of signal transduction in family a G-protein-coupled receptors (GPCRs). J Biol Chem (2011) 0.86
Monomerization as a prerequisite for intramolecular cleavage and shedding of the thyrotropin receptor. Endocrinology (2004) 0.84
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Molecular sampling of the allosteric binding pocket of the TSH receptor provides discriminative pharmacophores for antagonist and agonists. Biochem Soc Trans (2013) 0.82
The thyrotropin receptor hinge region as a surrogate ligand: identification of loci contributing to the coupling of thyrotropin binding and receptor activation. Endocrinology (2012) 0.81
Allosteric modulators hit the TSH receptor. Endocrinology (2014) 0.80
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The thyroid and pregnancy: a novel risk factor for very preterm delivery. Thyroid (2005) 1.82
Hyperthyroid-associated osteoporosis is exacerbated by the loss of TSH signaling. J Clin Invest (2012) 1.77
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Intermittent recombinant TSH injections prevent ovariectomy-induced bone loss. Proc Natl Acad Sci U S A (2008) 1.46
A comparison of short-term changes in health-related quality of life in thyroid carcinoma patients undergoing diagnostic evaluation with recombinant human thyrotropin compared with thyroid hormone withdrawal. J Clin Endocrinol Metab (2006) 1.45
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Characterization of thyrotropin receptor antibody-induced signaling cascades. Endocrinology (2008) 1.37
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Severe anemia in the Nan mutant mouse caused by sequence-selective disruption of erythroid Kruppel-like factor. Proc Natl Acad Sci U S A (2010) 1.34
Ankyrin binding mediates L1CAM interactions with static components of the cytoskeleton and inhibits retrograde movement of L1CAM on the cell surface. J Cell Biol (2003) 1.30
TNFalpha mediates the skeletal effects of thyroid-stimulating hormone. Proc Natl Acad Sci U S A (2006) 1.27
Activating autoantibodies to the beta-1 adrenergic and m2 muscarinic receptors facilitate atrial fibrillation in patients with Graves' hyperthyroidism. J Am Coll Cardiol (2009) 1.26
Committing embryonic stem cells to differentiate into thyrocyte-like cells in vitro. Endocrinology (2003) 1.25
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A monoclonal thyroid-stimulating antibody. J Clin Invest (2002) 1.22
Dissecting genetic heterogeneity in autoimmune thyroid diseases by subset analysis. J Autoimmun (2007) 1.18
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Ligand-dependent inhibition of oligomerization at the human thyrotropin receptor. J Biol Chem (2002) 1.16
Possible interaction between HLA-DRbeta1 and thyroglobulin variants in Graves' disease. Thyroid (2006) 1.15
Thyrotropin-independent induction of thyroid endoderm from embryonic stem cells by activin A. Endocrinology (2008) 1.14
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Molecular amino acid signatures in the MHC class II peptide-binding pocket predispose to autoimmune thyroiditis in humans and in mice. Proc Natl Acad Sci U S A (2008) 1.08
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Blocking antibody to the β-subunit of FSH prevents bone loss by inhibiting bone resorption and stimulating bone synthesis. Proc Natl Acad Sci U S A (2012) 1.04
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Fine mapping of loci linked to autoimmune thyroid disease identifies novel susceptibility genes. J Clin Endocrinol Metab (2012) 1.01
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Interactions between the L1 cell adhesion molecule and ezrin support traction-force generation and can be regulated by tyrosine phosphorylation. J Neurosci Res (2008) 0.98
Influence of the TSH receptor gene on susceptibility to Graves' disease and Graves' ophthalmopathy. Thyroid (2008) 0.98
'Linkage analysis of thyroid antibody production: evidence for shared susceptibility to clinical autoimmune thyroid disease. J Clin Endocrinol Metab (2008) 0.97
A C/T single nucleotide polymorphism at the tyrosine kinase domain of the insulin receptor gene is associated with polycystic ovary syndrome. Fertil Steril (2002) 0.96
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Calculation of the free energy and cooperativity of protein folding. PLoS One (2007) 0.96
The influence of thyroid-stimulating hormone and thyroid-stimulating hormone receptor antibodies on osteoclastogenesis. Thyroid (2011) 0.95
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The eventual pain and joy of grant writing. Thyroid (2005) 0.93
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Computer aided identification of small molecules disrupting uPAR/alpha5beta1--integrin interaction: a new paradigm for metastasis prevention. PLoS One (2009) 0.93
Structure-guided design of potent diazobenzene inhibitors for the BET bromodomains. J Med Chem (2013) 0.93
Analysis of immune regulatory genes in familial and sporadic Graves' disease. J Clin Endocrinol Metab (2004) 0.92
Delineating the autoimmune mechanisms in Graves' disease. Immunol Res (2012) 0.92
Structure-guided optimization of small molecules inhibiting human immunodeficiency virus 1 Tat association with the human coactivator p300/CREB binding protein-associated factor. J Med Chem (2007) 0.92
CCR7 deficiency in NOD mice leads to thyroiditis and primary hypothyroidism. J Immunol (2009) 0.92
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Stemness in human thyroid cancers and derived cell lines: the role of asymmetrically dividing cancer stem cells resistant to chemotherapy. J Clin Endocrinol Metab (2014) 0.91
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Homology modeling and site-directed mutagenesis to identify selective inhibitors of endothelin-converting enzyme-2. J Med Chem (2008) 0.90
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Dissecting linear and conformational epitopes on the native thyrotropin receptor. Endocrinology (2004) 0.89
Concentration-dependent regulation of thyrotropin receptor function by thyroid-stimulating antibody. J Clin Invest (2004) 0.89
Genetic profiling in Graves' disease: further evidence for lack of a distinct genetic contribution to Graves' ophthalmopathy. Thyroid (2012) 0.89
Human embryonic stem cells form functional thyroid follicles. Thyroid (2015) 0.88
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How one TSH receptor antibody induces thyrocyte proliferation while another induces apoptosis. J Autoimmun (2013) 0.87
Really significant genes for autoimmune thyroid disease do not exist--so how can we predict disease? Thyroid (2007) 0.87
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Thyrotropin receptor knockout mice: studies on immunological tolerance to a major thyroid autoantigen. Endocrinology (2003) 0.87
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Time for the American Thyroid Association to lead on thyroid screening in pregnancy. Thyroid (2007) 0.86
Studies of base pair sequence effects on DNA solvation based on all-atom molecular dynamics simulations. J Biosci (2012) 0.86
A tyrosine residue on the TSH receptor stabilizes multimer formation. PLoS One (2010) 0.85
mRNA-Seq reveals novel molecular mechanisms and a robust fingerprint in Graves' disease. J Clin Endocrinol Metab (2014) 0.85
Lucanthone and its derivative hycanthone inhibit apurinic endonuclease-1 (APE1) by direct protein binding. PLoS One (2011) 0.85