Thomas N Wight

Author PubWeight™ 139.48‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Human tissue-engineered blood vessels for adult arterial revascularization. Nat Med 2006 3.39
2 Early human atherosclerosis: accumulation of lipid and proteoglycans in intimal thickenings followed by macrophage infiltration. Arterioscler Thromb Vasc Biol 2007 2.58
3 Hyaluronan-cell interactions in cancer and vascular disease. J Biol Chem 2001 2.45
4 Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A 2006 2.28
5 Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1. J Biol Chem 2003 2.10
6 SPARC-null mice display abnormalities in the dermis characterized by decreased collagen fibril diameter and reduced tensile strength. J Invest Dermatol 2003 1.98
7 Cardiovascular pathology in Hutchinson-Gilford progeria: correlation with the vascular pathology of aging. Arterioscler Thromb Vasc Biol 2010 1.96
8 Adipocyte-derived serum amyloid A3 and hyaluronan play a role in monocyte recruitment and adhesion. Diabetes 2007 1.95
9 Enhanced extracellular matrix accumulation in restenosis of coronary arteries after stent deployment. J Am Coll Cardiol 2002 1.92
10 Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1. Proc Natl Acad Sci U S A 2012 1.91
11 Extracellular matrix molecules: potential targets in pharmacotherapy. Pharmacol Rev 2009 1.90
12 Maintenance of chondroitin sulfation balance by chondroitin-4-sulfotransferase 1 is required for chondrocyte development and growth factor signaling during cartilage morphogenesis. Development 2005 1.88
13 Transforming growth factor beta 1 induces neointima formation through plasminogen activator inhibitor-1-dependent pathways. Arterioscler Thromb Vasc Biol 2005 1.87
14 The ADAMTS proteases, extracellular matrix, and vascular disease: waking the sleeping giant(s)! Arterioscler Thromb Vasc Biol 2005 1.76
15 Hyaluronan-dependent pericellular matrix. Adv Drug Deliv Rev 2007 1.73
16 Intracellular hyaluronan: a new frontier for inflammation? Biochim Biophys Acta 2004 1.64
17 Increase in serum amyloid a evoked by dietary cholesterol is associated with increased atherosclerosis in mice. Circulation 2004 1.61
18 Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: dissociation of adipocyte hypertrophy from inflammation. Diabetes 2009 1.58
19 Early atherosclerosis in humans: role of diffuse intimal thickening and extracellular matrix proteoglycans. Cardiovasc Res 2008 1.44
20 Serum amyloid A and lipoprotein retention in murine models of atherosclerosis. Arterioscler Thromb Vasc Biol 2005 1.43
21 Cutting edge: high molecular weight hyaluronan promotes the suppressive effects of CD4+CD25+ regulatory T cells. J Immunol 2007 1.38
22 Triglyceride-rich lipoproteins from subjects with type 2 diabetes do not demonstrate increased binding to biglycan, a vascular proteoglycan. J Clin Endocrinol Metab 2002 1.38
23 The regulated synthesis of versican, decorin, and biglycan: extracellular matrix proteoglycans that influence cellular phenotype. Crit Rev Eukaryot Gene Expr 2004 1.36
24 A role for decorin in cutaneous wound healing and angiogenesis. Wound Repair Regen 2006 1.33
25 Extracellular matrix changes in stented human coronary arteries. Circulation 2004 1.32
26 Differential accumulation of proteoglycans and hyaluronan in culprit lesions: insights into plaque erosion. Arterioscler Thromb Vasc Biol 2002 1.31
27 Glycosaminoglycans and proteoglycans in normal mitral valve leaflets and chordae: association with regions of tensile and compressive loading. Glycobiology 2004 1.30
28 CD44 costimulation promotes FoxP3+ regulatory T cell persistence and function via production of IL-2, IL-10, and TGF-beta. J Immunol 2009 1.28
29 Overexpression of the V3 variant of versican alters arterial smooth muscle cell adhesion, migration, and proliferation in vitro. J Cell Physiol 2002 1.27
30 Inhibition of versican synthesis by antisense alters smooth muscle cell phenotype and induces elastic fiber formation in vitro and in neointima after vessel injury. Circ Res 2005 1.24
31 Kinetics of chemokine-glycosaminoglycan interactions control neutrophil migration into the airspaces of the lungs. J Immunol 2010 1.23
32 Versican degradation and vascular disease. Trends Cardiovasc Med 2006 1.23
33 Changes in elastin, elastin binding protein and versican in alveoli in chronic obstructive pulmonary disease. Respir Res 2008 1.22
34 Retrovirally mediated overexpression of versican v3 by arterial smooth muscle cells induces tropoelastin synthesis and elastic fiber formation in vitro and in neointima after vascular injury. Circ Res 2002 1.21
35 Retrovirally mediated overexpression of versican v3 reverses impaired elastogenesis and heightened proliferation exhibited by fibroblasts from Costello syndrome and Hurler disease patients. Am J Pathol 2004 1.21
36 Intact extracellular matrix and the maintenance of immune tolerance: high molecular weight hyaluronan promotes persistence of induced CD4+CD25+ regulatory T cells. J Leukoc Biol 2009 1.20
37 Pro- and anti-inflammatory factors cooperate to control hyaluronan synthesis in lung fibroblasts. Am J Respir Cell Mol Biol 2004 1.18
38 ECM components guide IL-10 producing regulatory T-cell (TR1) induction from effector memory T-cell precursors. Proc Natl Acad Sci U S A 2011 1.17
39 Alterations in the lens capsule contribute to cataractogenesis in SPARC-null mice. J Cell Sci 2002 1.17
40 Binding of interleukin-8 to heparan sulfate and chondroitin sulfate in lung tissue. Am J Respir Cell Mol Biol 2003 1.17
41 Heparan sulfate in perlecan promotes mouse atherosclerosis: roles in lipid permeability, lipid retention, and smooth muscle cell proliferation. Circ Res 2008 1.15
42 Hyaluronan and versican in the control of human T-lymphocyte adhesion and migration. Matrix Biol 2011 1.15
43 A novel rat model of carotid artery stenting for the understanding of restenosis in metabolic diseases. J Vasc Res 2002 1.14
44 Organization of hyaluronan and versican in the extracellular matrix of human fibroblasts treated with the viral mimetic poly I:C. J Histochem Cytochem 2009 1.13
45 Overexpression of hyaluronan synthases alters vascular smooth muscle cell phenotype and promotes monocyte adhesion. J Cell Physiol 2006 1.13
46 Proteoglycans synthesized by arterial smooth muscle cells in the presence of transforming growth factor-beta1 exhibit increased binding to LDLs. Arterioscler Thromb Vasc Biol 2002 1.11
47 Polyinosine-polycytidylic acid stimulates versican accumulation in the extracellular matrix promoting monocyte adhesion. Am J Respir Cell Mol Biol 2009 1.10
48 Matricellular hevin regulates decorin production and collagen assembly. J Biol Chem 2006 1.09
49 Serum amyloid A facilitates the binding of high-density lipoprotein from mice injected with lipopolysaccharide to vascular proteoglycans. Arterioscler Thromb Vasc Biol 2011 1.08
50 Intracellular hyaluronan in arterial smooth muscle cells: association with microtubules, RHAMM, and the mitotic spindle. J Histochem Cytochem 2004 1.07
51 Developing vasculature and stroma in engineered human myocardium. Tissue Eng Part A 2011 1.07
52 Proteoglycans: key regulators of pulmonary inflammation and the innate immune response to lung infection. Anat Rec (Hoboken) 2010 1.06
53 Lung lining fluid glutathione attenuates IL-13-induced asthma. Am J Respir Cell Mol Biol 2007 1.06
54 Synthesis and organization of hyaluronan and versican by embryonic stem cells undergoing embryoid body differentiation. J Histochem Cytochem 2009 1.05
55 Monocyte-to-macrophage differentiation: synthesis and secretion of a complex extracellular matrix. J Biol Chem 2012 1.02
56 Changes in perlecan expression during vascular injury: role in the inhibition of smooth muscle cell proliferation in the late lesion. Arterioscler Thromb Vasc Biol 2003 1.01
57 Diabetes and arterial extracellular matrix changes in a porcine model of atherosclerosis. J Histochem Cytochem 2007 1.01
58 Cutaneous chronic graft-versus-host disease does not have the abnormal endothelial phenotype or vascular rarefaction characteristic of systemic sclerosis. PLoS One 2009 0.99
59 V3 versican isoform expression has a dual role in human melanoma tumor growth and metastasis. Lab Invest 2006 0.99
60 Versican-thrombospondin-1 binding in vitro and colocalization in microfibrils induced by inflammation on vascular smooth muscle cells. J Cell Sci 2006 0.99
61 Neointima formed by arterial smooth muscle cells expressing versican variant V3 is resistant to lipid and macrophage accumulation. Arterioscler Thromb Vasc Biol 2011 0.99
62 miRNAs regulate expression and function of extracellular matrix molecules. Matrix Biol 2012 0.98
63 Cell-associated and extracellular phospholipid transfer protein in human coronary atherosclerosis. Circulation 2003 0.98
64 Native fibrillar collagen membranes of micron-scale and submicron thicknesses for cell support and perfusion. Biomaterials 2005 0.97
65 Inhibition of glycosaminoglycan synthesis and protein glycosylation with WAS-406 and azaserine result in reduced islet amyloid formation in vitro. Am J Physiol Cell Physiol 2007 0.97
66 Retrovirally mediated overexpression of glycosaminoglycan-deficient biglycan in arterial smooth muscle cells induces tropoelastin synthesis and elastic fiber formation in vitro and in neointimae after vascular injury. Am J Pathol 2008 0.96
67 Propagation and control of T cell responses by heparan sulfate-bound IL-2. J Immunol 2003 0.96
68 The role of hyaluronan and the extracellular matrix in islet inflammation and immune regulation. Curr Diab Rep 2012 0.96
69 Smooth muscle cell biglycan overexpression results in increased lipoprotein retention on extracellular matrix: implications for the retention of lipoproteins in atherosclerosis. Atherosclerosis 2004 0.95
70 Athsq1 is an atherosclerosis modifier locus with dramatic effects on lesion area and prominent accumulation of versican. Arterioscler Thromb Vasc Biol 2008 0.95
71 Microgrooved fibrillar collagen membranes as scaffolds for cell support and alignment. Biomaterials 2005 0.95
72 Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse. Cell Mol Immunol 2010 0.94
73 Increased plasmin and serine proteinase activity during flow-induced intimal atrophy in baboon PTFE grafts. Arterioscler Thromb Vasc Biol 2002 0.94
74 Interleukin-1beta selectively decreases the synthesis of versican by arterial smooth muscle cells. J Cell Biochem 2007 0.94
75 SPARC-thrombospondin-2-double-null mice exhibit enhanced cutaneous wound healing and increased fibrovascular invasion of subcutaneous polyvinyl alcohol sponges. J Histochem Cytochem 2005 0.93
76 PDGF beta-receptor kinase activity and ERK1/2 mediate glycosaminoglycan elongation on biglycan and increases binding to LDL. Endocrinology 2010 0.92
77 V3 versican isoform expression alters the phenotype of melanoma cells and their tumorigenic potential. Int J Cancer 2005 0.92
78 Proteolytic cleavage of versican and involvement of ADAMTS-1 in VEGF-A/VPF-induced pathological angiogenesis. J Histochem Cytochem 2011 0.92
79 Syndecan-4 regulates early neutrophil migration and pulmonary inflammation in response to lipopolysaccharide. Am J Respir Cell Mol Biol 2012 0.91
80 ApoC-III content of apoB-containing lipoproteins is associated with binding to the vascular proteoglycan biglycan. J Lipid Res 2002 0.91
81 Removal of heparan sulfate by heparinase treatment inhibits FGF-2-dependent smooth muscle cell proliferation in injured rat carotid arteries. Atherosclerosis 2004 0.91
82 Proteoglycans synthesized and secreted by pancreatic islet beta-cells bind amylin. Arch Biochem Biophys 2003 0.90
83 Accumulation and loss of extracellular matrix during shear stress-mediated intimal growth and regression in baboon vascular grafts. J Histochem Cytochem 2005 0.90
84 Decorin promotes aortic smooth muscle cell calcification and colocalizes to calcified regions in human atherosclerotic lesions. Arterioscler Thromb Vasc Biol 2004 0.90
85 Tesaglitazar, a dual peroxisome proliferator-activated receptor alpha/gamma agonist, reduces atherosclerosis in female low density lipoprotein receptor deficient mice. Atherosclerosis 2007 0.90
86 Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults. Mech Dev 2013 0.90
87 Hyaluronan accumulation is elevated in cultures of low density lipoprotein receptor-deficient cells and is altered by manipulation of cell cholesterol content. J Biol Chem 2008 0.89
88 Hyaluronan and hyaluronan binding proteins are normal components of mouse pancreatic islets and are differentially expressed by islet endocrine cell types. J Histochem Cytochem 2012 0.88
89 Superficial pseudoaneurysms: clinicopathologic aspects and involvement of extracellular matrix proteoglycans. Mod Pathol 2004 0.87
90 The vascular endothelial growth factor VEGF165 induces perlecan synthesis via VEGF receptor-2 in cultured human brain microvascular endothelial cells. Biochim Biophys Acta 2006 0.86
91 Lysophosphatidylcholine regulates synthesis of biglycan and the proteoglycan form of macrophage colony stimulating factor. Arterioscler Thromb Vasc Biol 2003 0.86
92 Perlecan: a major IL-2-binding proteoglycan in murine spleen. Immunol Cell Biol 2007 0.86
93 The accumulation of specific types of proteoglycans in eroded plaques: a role in coronary thrombosis in the absence of rupture. Curr Opin Lipidol 2004 0.86
94 Differentiation of cardiomyocytes from human embryonic stem cells is accompanied by changes in the extracellular matrix production of versican and hyaluronan. J Cell Biochem 2010 0.86
95 Overexpression of decorin by rat arterial smooth muscle cells enhances contraction of type I collagen in vitro. Arterioscler Thromb Vasc Biol 2003 0.86
96 ADAMTS-4 and biglycan are expressed at high levels and co-localize to podosomes during endothelial cell tubulogenesis in vitro. J Histochem Cytochem 2013 0.85
97 Antioxidants inhibit the ability of lysophosphatidylcholine to regulate proteoglycan synthesis. Arterioscler Thromb Vasc Biol 2005 0.85
98 Sirolimus blocks the accumulation of hyaluronan (HA) by arterial smooth muscle cells and reduces monocyte adhesion to the ECM. Atherosclerosis 2006 0.85
99 Extracellular matrix components in the pathogenesis of type 1 diabetes. Curr Diab Rep 2014 0.85
100 Expression of versican isoform V3 in the absence of ascorbate improves elastogenesis in engineered vascular constructs. Tissue Eng Part A 2010 0.84
101 Arterial smooth muscle cell proteoglycans synthesized in the presence of glucosamine demonstrate reduced binding to LDL. J Lipid Res 2002 0.84
102 Sputum hyaluronan and versican in severe eosinophilic asthma. Int Arch Allergy Immunol 2012 0.84
103 The accumulation of versican in the nodules of benign prostatic hyperplasia. Prostate 2009 0.83
104 Endogenous overexpression of hyaluronan synthases within dynamically cultured collagen gels: Implications for vascular and valvular disease. Biomaterials 2008 0.83
105 Oxidized low density lipoprotein (LDL) affects hyaluronan synthesis in human aortic smooth muscle cells. J Biol Chem 2013 0.82
106 Inhibition of hyaluronan synthesis restores immune tolerance during autoimmune insulitis. J Clin Invest 2015 0.82
107 Platelet-derived growth factor differentially regulates the expression and post-translational modification of versican by arterial smooth muscle cells through distinct protein kinase C and extracellular signal-regulated kinase pathways. J Biol Chem 2009 0.82
108 Statin-exposed vascular smooth muscle cells secrete proteoglycans with decreased binding affinity for LDL. J Lipid Res 2003 0.81
109 Apolipoprotein E mediates the retention of high-density lipoproteins by mouse carotid arteries and cultured arterial smooth muscle cell extracellular matrices. Circ Res 2002 0.81
110 Blockade of TGF-β by catheter-based local intravascular gene delivery does not alter the in-stent neointimal response, but enhances inflammation in pig coronary arteries. Int J Cardiol 2010 0.80
111 The effect of PPAR ligands to modulate glucose metabolism alters the incorporation of metabolic precursors into proteoglycans synthesized by human vascular smooth muscle cells. Arch Physiol Biochem 2008 0.80
112 Cleavage of hyaluronan is impaired in aged dermal wounds. Matrix Biol 2012 0.80
113 Decorin synthesized by arterial smooth muscle cells is retained in fibrin gels and modulates fibrin contraction. J Cell Biochem 2007 0.80
114 Hyaluronan in aged collagen matrix increases prostate epithelial cell proliferation. In Vitro Cell Dev Biol Anim 2014 0.79
115 Serum amyloid A impairs the antiinflammatory properties of HDL. J Clin Invest 2015 0.78
116 Glucosamine supplementation accelerates early but not late atherosclerosis in LDL receptor-deficient mice. J Nutr 2006 0.78
117 Overall sulfation of heparan sulfate from pancreatic islet β-TC3 cells increases maximal fibril formation but does not determine binding to the amyloidogenic peptide islet amyloid polypeptide. J Biol Chem 2012 0.78
118 Regulation of proteoglycan synthesis by leukotriene d4 and epidermal growth factor in bronchial smooth muscle cells. Am J Respir Cell Mol Biol 2003 0.78
119 Characterization of chondroitin/dermatan sulfate proteoglycans synthesized by bovine retinal pericytes in culture. Biol Pharm Bull 2004 0.77
120 Serum amyloid A impairs the antiinflammatory properties of HDL. J Clin Invest 2016 0.77
121 Extended life span is associated with insulin resistance in a transgenic mouse model of insulinoma secreting human islet amyloid polypeptide. Am J Physiol Endocrinol Metab 2003 0.77
122 The detection of glycosaminoglycans in pancreatic islets and lymphoid tissues. Methods Mol Biol 2015 0.76
123 Age-dependent loss of MMP-3 in Hutchinson-Gilford progeria syndrome. J Gerontol A Biol Sci Med Sci 2011 0.76
124 Detection of coronary atherosclerotic plaques with superficial proteoglycans and foam cells using real-time intrinsic fluorescence spectroscopy. Atherosclerosis 2010 0.75
125 The effect of endogenous overexpression of hyaluronan synthases on material, morphological, and biochemical properties of uncrosslinked collagen biomaterials. Biomaterials 2007 0.75