Effect of Genetic African Ancestry on eGFR and Kidney Disease.

PubWeight™: 0.87‹?›

🔗 View Article (PMID 25349204)

Published in J Am Soc Nephrol on October 27, 2014

Authors

Miriam S Udler1, Girish N Nadkarni2, Gillian Belbin3, Vaneet Lotay4, Christina Wyatt5, Omri Gottesman6, Erwin P Bottinger2, Eimear E Kenny7, Inga Peter8

Author Affiliations

1: Departments of Medicine and Genetics and Genomic Sciences, The Charles Bronfman Institute for Personalized Medicine, mudler@mgh.harvard.edu.
2: Departments of Medicine and The Charles Bronfman Institute for Personalized Medicine, Division of Nephrology.
3: Genetics and Genomic Sciences, The Charles Bronfman Institute for Personalized Medicine.
4: The Charles Bronfman Institute for Personalized Medicine.
5: Departments of Medicine and Division of Nephrology.
6: Departments of Medicine and The Charles Bronfman Institute for Personalized Medicine.
7: Genetics and Genomic Sciences, The Charles Bronfman Institute for Personalized Medicine, The Center for Statistical Genetics, and The Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York.
8: Genetics and Genomic Sciences, The Charles Bronfman Institute for Personalized Medicine, The Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York.

Articles cited by this

PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92

A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med (1999) 82.86

A new equation to estimate glomerular filtration rate. Ann Intern Med (2009) 71.41

An integrated map of genetic variation from 1,092 human genomes. Nature (2012) 59.82

Population structure and eigenanalysis. PLoS Genet (2006) 37.21

A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet (2009) 30.09

Association of trypanolytic ApoL1 variants with kidney disease in African Americans. Science (2010) 16.00

Fast model-based estimation of ancestry in unrelated individuals. Genome Res (2009) 15.63

MYH9 is associated with nondiabetic end-stage renal disease in African Americans. Nat Genet (2008) 9.50

Genotype imputation with thousands of genomes. G3 (Bethesda) (2011) 8.77

Sensitive detection of chromosomal segments of distinct ancestry in admixed populations. PLoS Genet (2009) 6.36

Reconstructing genetic ancestry blocks in admixed individuals. Am J Hum Genet (2006) 5.92

Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene. Hum Genet (2010) 5.68

Improved whole-chromosome phasing for disease and population genetic studies. Nat Methods (2013) 5.43

Genome-wide patterns of population structure and admixture in West Africans and African Americans. Proc Natl Acad Sci U S A (2009) 5.39

APOL1 risk variants, race, and progression of chronic kidney disease. N Engl J Med (2013) 5.00

APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy. J Am Soc Nephrol (2011) 4.80

Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association study. J Am Med Inform Assoc (2011) 4.20

Operational implementation of prospective genotyping for personalized medicine: the design of the Vanderbilt PREDICT project. Clin Pharmacol Ther (2012) 4.05

Appendicular skeletal muscle mass: effects of age, gender, and ethnicity. J Appl Physiol (1985) (1997) 3.63

Colloquium paper: genome-wide patterns of population structure and admixture among Hispanic/Latino populations. Proc Natl Acad Sci U S A (2010) 3.20

Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type 2 diabetes mellitus-associated ESRD. Nephrol Dial Transplant (2009) 2.88

Population-based risk assessment of APOL1 on renal disease. J Am Soc Nephrol (2011) 2.81

APOL1 variants associate with increased risk of CKD among African Americans. J Am Soc Nephrol (2013) 1.98

Evaluation of the Chronic Kidney Disease Epidemiology Collaboration equation for estimating the glomerular filtration rate in multiple ethnicities. Kidney Int (2010) 1.81

A quasi-Newton acceleration for high-dimensional optimization algorithms. Stat Comput (2011) 1.80

Genetic variation in APOL1 associates with younger age at hemodialysis initiation. J Am Soc Nephrol (2011) 1.70

Reconstructing the population genetic history of the Caribbean. PLoS Genet (2013) 1.68

Influence of race, ethnicity and socioeconomic status on kidney disease. Nat Rev Nephrol (2012) 1.67

Race and ancestry in biomedical research: exploring the challenges. Genome Med (2009) 1.55

APOL1 allelic variants are associated with lower age of dialysis initiation and thereby increased dialysis vintage in African and Hispanic Americans with non-diabetic end-stage kidney disease. Nephrol Dial Transplant (2012) 1.42

The CLIPMERGE PGx Program: clinical implementation of personalized medicine through electronic health records and genomics-pharmacogenomics. Clin Pharmacol Ther (2013) 1.37

Reconstructing Native American migrations from whole-genome and whole-exome data. PLoS Genet (2013) 1.34

Differences in albuminuria between Hispanics and whites: an evaluation by genetic ancestry and country of origin: the multi-ethnic study of atherosclerosis. Circ Cardiovasc Genet (2010) 1.23

Genetic background of patients from a university medical center in Manhattan: implications for personalized medicine. PLoS One (2011) 1.21

Racial differences in early-onset renal disease among young adults: the coronary artery risk development in young adults (CARDIA) study. J Am Soc Nephrol (2003) 1.08

Imputation-based genomic coverage assessments of current human genotyping arrays. G3 (Bethesda) (2013) 1.06

Race and creatinine excretion in chronic renal insufficiency. Am J Kidney Dis (1997) 0.99

Are the creatinine-based equations accurate to estimate glomerular filtration rate in African American populations? Clin J Am Soc Nephrol (2011) 0.89

The Association of African Ancestry and elevated creatinine in the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am J Nephrol (2009) 0.86

Accuracy of imputation to infer unobserved APOE epsilon alleles in genome-wide genotyping data. Eur J Hum Genet (2014) 0.82