Published in Am J Physiol Renal Physiol on October 29, 2014
Renal Dysfunction, Rather Than Nonrenal Vascular Dysfunction, Mediates Salt-Induced Hypertension. Circulation (2016) 1.21
Phenotype-Specific Treatment of Heart Failure With Preserved Ejection Fraction: A Multiorgan Roadmap. Circulation (2016) 1.14
Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats. Hypertension (2015) 0.85
Reprogramming: A Preventive Strategy in Hypertension Focusing on the Kidney. Int J Mol Sci (2015) 0.82
Effects of p67phox on the mitochondrial oxidative state in the kidney of Dahl salt-sensitive rats: optical fluorescence 3-D cryoimaging. Am J Physiol Renal Physiol (2015) 0.79
Hypertension and Diabetes Mellitus: The Chicken and Egg Problem. Hypertension (2017) 0.75
Proton channels and renal hypertensive injury: a key piece of the Dahl salt-sensitive rat puzzle? Am J Physiol Regul Integr Comp Physiol (2016) 0.75
Hypertension: a problem of organ blood flow supply-demand mismatch. Future Cardiol (2016) 0.75
Hydrogen Peroxide and Sodium Transport in the Lung and Kidney. Biomed Res Int (2016) 0.75
Mitochondrial Reactive Oxygen Species and Kidney Hypoxia in the Development of Diabetic Nephropathy. Front Physiol (2017) 0.75
The gene-expression profile of renal medulla in ISIAH rats with inherited stress-induced arterial hypertension. BMC Genet (2016) 0.75
Increased renal oxidative stress in salt-sensitive human GRK4γ486V transgenic mice. Free Radic Biol Med (2017) 0.75
Role of Nox4 and p67phox subunit of Nox2 in ROS production in response to increased tubular flow in the mTAL of Dahl salt-sensitive rats. Am J Physiol Renal Physiol (2016) 0.75
Inhibition of Mammalian Target of Rapamycin Complex 1 Attenuates Salt-Induced Hypertension and Kidney Injury in Dahl Salt-Sensitive Rats. Hypertension (2017) 0.75
Renal sodium handling and sodium sensitivity. Kidney Res Clin Pract (2017) 0.75
Melatonin, mitochondria and hypertension. Cell Mol Life Sci (2017) 0.75
Regulation and function of renal medullary cyclooxygenase-2 during high salt loading. Front Biosci (Landmark Ed) (2017) 0.75
The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev (2007) 21.13
Knockout rats via embryo microinjection of zinc-finger nucleases. Science (2009) 12.33
The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem J (1973) 7.01
The reaction of no with superoxide. Free Radic Res Commun (1993) 5.65
Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction: linking mitochondrial oxidative damage and vascular endothelial dysfunction. Circ Res (2007) 4.48
Nox4 is a protective reactive oxygen species generating vascular NADPH oxidase. Circ Res (2012) 4.19
NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation. Biochem J (2007) 3.88
Salt sensitivity of blood pressure in humans. Hypertension (1996) 3.58
Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations. Free Radic Biol Med (2011) 3.58
Fluorescent and luminescent probes for measurement of oxidative and nitrosative species in cells and tissues: progress, pitfalls, and prospects. Free Radic Biol Med (2007) 3.56
Specific aquaporins facilitate the diffusion of hydrogen peroxide across membranes. J Biol Chem (2006) 3.54
Salt in health and disease--a delicate balance. N Engl J Med (2013) 3.49
Function of the thick ascending limb of Henle's loop. Am J Physiol (1973) 3.48
Chemistry and biology of reactive oxygen species in signaling or stress responses. Nat Chem Biol (2011) 3.36
Angiotensin II stimulation of NAD(P)H oxidase activity: upstream mediators. Circ Res (2002) 3.32
NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities. Diabetes Care (2008) 3.07
Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system. Circ Res (2012) 3.02
Simulation of the diffusion and reaction of endogenously produced nitric oxide. Proc Natl Acad Sci U S A (1994) 2.99
Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney. J Biol Chem (2005) 2.98
Hydrogen peroxide fluxes and compartmentalization inside growing Escherichia coli. J Bacteriol (2001) 2.96
Ion transport mechanisms in thick ascending limb of Henle's loop of mammalian nephron. Physiol Rev (1985) 2.94
Cellular and molecular mechanisms of endothelial cell dysfunction. J Clin Invest (1997) 2.91
Poldip2, a novel regulator of Nox4 and cytoskeletal integrity in vascular smooth muscle cells. Circ Res (2009) 2.83
NADPH oxidases in the kidney. Antioxid Redox Signal (2006) 2.70
Methods for detection of reactive metabolites of oxygen and nitrogen: in vitro and in vivo considerations. Am J Physiol Regul Integr Comp Physiol (2004) 2.61
Long-term control of arterial blood pressure. Physiol Rev (1992) 2.29
A targetable fluorescent probe for imaging hydrogen peroxide in the mitochondria of living cells. J Am Chem Soc (2008) 2.23
The E-loop is involved in hydrogen peroxide formation by the NADPH oxidase Nox4. J Biol Chem (2011) 2.20
Aquaporin-3 mediates hydrogen peroxide uptake to regulate downstream intracellular signaling. Proc Natl Acad Sci U S A (2010) 2.20
Increased expression of NAD(P)H oxidase subunit p67(phox) in the renal medulla contributes to excess oxidative stress and salt-sensitive hypertension. Cell Metab (2012) 2.18
Renal ischemia: a new perspective. Kidney Int (1984) 2.15
Intratubular renin-angiotensin system in hypertension. Hypertension (2011) 2.14
Inhibition of cyclooxygenase-2 in the rat renal medulla leads to sodium-sensitive hypertension. Hypertension (2004) 2.14
A selective, cell-permeable optical probe for hydrogen peroxide in living cells. J Am Chem Soc (2004) 2.08
NADPH oxidase in the renal medulla causes oxidative stress and contributes to salt-sensitive hypertension in Dahl S rats. Hypertension (2006) 1.99
Brown Norway chromosome 13 confers protection from high salt to consomic Dahl S rat. Hypertension (2001) 1.99
Role of renal medullary heme oxygenase in the regulation of pressure natriuresis and arterial blood pressure. Hypertension (2006) 1.92
Ultrastructural quantitation of mitochondria and myofilaments in cardiac muscle from 10 different animal species including man. J Mol Cell Cardiol (1992) 1.89
T lymphocytes mediate hypertension and kidney damage in Dahl salt-sensitive rats. Am J Physiol Regul Integr Comp Physiol (2010) 1.84
NAD(P)H oxidase mediates TGF-beta1-induced activation of kidney myofibroblasts. J Am Soc Nephrol (2009) 1.80
Urinary potassium excretion and sodium sensitivity in blacks. Hypertension (2004) 1.79
Effects of NADPH oxidase inhibitor in diabetic nephropathy. Kidney Int (2005) 1.78
Production and actions of superoxide in the renal medulla. Hypertension (2001) 1.76
Oxidative stress, renal infiltration of immune cells, and salt-sensitive hypertension: all for one and one for all. Am J Physiol Renal Physiol (2004) 1.76
Salt intake, oxidative stress, and renal expression of NADPH oxidase and superoxide dismutase. J Am Soc Nephrol (2003) 1.75
Expression and cellular localization of classic NADPH oxidase subunits in the spontaneously hypertensive rat kidney. Hypertension (2002) 1.73
Hydrogen peroxide as a paracrine vascular mediator: regulation and signaling leading to dysfunction. Exp Biol Med (Maywood) (2006) 1.73
Control of NaCl transport in the thick ascending limb. Am J Physiol (1984) 1.72
Renal medullary oxidative stress, pressure-natriuresis, and hypertension. Hypertension (2008) 1.72
Nox2 redox signaling maintains essential cell populations in the brain. Nat Chem Biol (2010) 1.70
Immune suppression attenuates hypertension and renal disease in the Dahl salt-sensitive rat. Hypertension (2006) 1.65
Mechanisms of proximal tubule sodium transport regulation that link extracellular fluid volume and blood pressure. Am J Physiol Regul Integr Comp Physiol (2010) 1.63
The oxidation of 2',7'-dichlorofluorescin to reactive oxygen species: a self-fulfilling prophesy? Free Radic Biol Med (2005) 1.60
Do nitroxide antioxidants act as scavengers of O2-. or as SOD mimics? J Biol Chem (1996) 1.59
Multiple blood pressure loci on rat chromosome 13 attenuate development of hypertension in the Dahl S hypertensive rat. Physiol Genomics (2007) 1.57
Oxoammonium cation intermediate in the nitroxide-catalyzed dismutation of superoxide. Proc Natl Acad Sci U S A (1992) 1.54
Role of renal NO production in the regulation of medullary blood flow. Am J Physiol Regul Integr Comp Physiol (2003) 1.52
Generation of gene-specific mutated rats using zinc-finger nucleases. Methods Mol Biol (2010) 1.51
Regulation of cyclooxygenase expression in the kidney by dietary salt intake. Am J Physiol (1998) 1.51
Role of the renal medulla in volume and arterial pressure regulation. Am J Physiol (1997) 1.50
High perfusion pressure accelerates renal injury in salt-sensitive hypertension. J Am Soc Nephrol (2008) 1.50
Physiological regulation of cyclooxygenase-2 in the kidney. Am J Physiol Renal Physiol (2001) 1.50
Mycophenolate mofetil prevents salt-sensitive hypertension resulting from angiotensin II exposure. Kidney Int (2001) 1.50
Reactive oxygen species: roles in blood pressure and kidney function. Curr Hypertens Rep (2002) 1.47
Infiltrating T lymphocytes in the kidney increase oxidative stress and participate in the development of hypertension and renal disease. Am J Physiol Renal Physiol (2010) 1.46
Redox control of renal function and hypertension. Antioxid Redox Signal (2008) 1.45
Mycophenolate mofetil prevents salt-sensitive hypertension resulting from nitric oxide synthesis inhibition. Am J Physiol Renal Physiol (2001) 1.42
Structural insights into Nox4 and Nox2: motifs involved in function and cellular localization. Mol Cell Biol (2009) 1.41
Tubular sodium handling and tubuloglomerular feedback in experimental diabetes mellitus. Am J Physiol (1991) 1.40
Oxidative stress and antioxidant treatment in hypertension and the associated renal damage. Am J Nephrol (2005) 1.40
Transcutaneous measurement of renal function in conscious mice. Am J Physiol Renal Physiol (2012) 1.39
Angiotensin II-NAD(P)H oxidase-stimulated superoxide modifies tubulovascular nitric oxide cross-talk in renal outer medulla. Hypertension (2003) 1.38
Renal medullary microcirculation. Physiol Rev (1990) 1.37
Effect of renal medullary H2O2 on salt-induced hypertension and renal injury. Am J Physiol Regul Integr Comp Physiol (2005) 1.36
Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms. J Biol Chem (2002) 1.35
Voltage-gated proton channels: molecular biology, physiology, and pathophysiology of the H(V) family. Physiol Rev (2013) 1.35
Segmental synthesis and actions of prostaglandins along the nephron. Am J Physiol (1987) 1.34
Flow increases superoxide production by NADPH oxidase via activation of Na-K-2Cl cotransport and mechanical stress in thick ascending limbs. Am J Physiol Renal Physiol (2006) 1.33
Superoxide stimulates NaCl absorption in the thick ascending limb via activation of protein kinase C. Hypertension (2006) 1.32
NADPH oxidase contributes to renal damage and dysfunction in Dahl salt-sensitive hypertension. Am J Physiol Regul Integr Comp Physiol (2008) 1.31
Endothelium-dependent vascular responses in normotensive and hypertensive Dahl rats. Hypertension (1987) 1.30
Elevations in renal interstitial hydrostatic pressure and 20-hydroxyeicosatetraenoic acid contribute to pressure natriuresis. Hypertension (2007) 1.29
Role of Nox4 in murine models of kidney disease. Free Radic Biol Med (2012) 1.28
Salt-sensitive hypertension induced by decoy of transcription factor hypoxia-inducible factor-1alpha in the renal medulla. Circ Res (2008) 1.27
Enhanced superoxide production in renal outer medulla of Dahl salt-sensitive rats reduces nitric oxide tubular-vascular cross-talk. Hypertension (2007) 1.27
Effect of sodium delivery on superoxide and nitric oxide in the medullary thick ascending limb. Am J Physiol Renal Physiol (2006) 1.26
Effects of dietary salt on intrarenal angiotensin system, NAD(P)H oxidase, COX-2, MCP-1 and PAI-1 expressions and NF-kappaB activity in salt-sensitive and -resistant rat kidneys. Am J Nephrol (2007) 1.25
Novel role of fumarate metabolism in dahl-salt sensitive hypertension. Hypertension (2009) 1.25
Superoxide released to high intra-arteriolar pressure reduces nitric oxide-mediated shear stress- and agonist-induced dilations. Circ Res (1998) 1.25
Enhanced chloride reabsorption in the loop of Henle in Dahl salt-sensitive rats. Hypertension (1991) 1.25
Increased renal medullary oxidative stress produces hypertension. Hypertension (2002) 1.24
Racial differences in the incidence of chronic kidney disease. Clin J Am Soc Nephrol (2011) 1.24
Increased renal medullary H2O2 leads to hypertension. Hypertension (2003) 1.23
Early determinants of H2O2-induced endothelial dysfunction. Free Radic Biol Med (2006) 1.22
Genetics of salt-sensitive hypertension. Curr Hypertens Rep (2011) 1.21
Sympathoexcitation by oxidative stress in the brain mediates arterial pressure elevation in salt-sensitive hypertension. Hypertension (2007) 1.20
Methods for detection of mitochondrial and cellular reactive oxygen species. Antioxid Redox Signal (2012) 1.20
Interaction of O(2)(-) and NO in the thick ascending limb. Hypertension (2002) 1.19
Identification of novel Nox4 splice variants with impact on ROS levels in A549 cells. Biochem Biophys Res Commun (2005) 1.18
Decrease of H2O2 plasma membrane permeability during adaptation to H2O2 in Saccharomyces cerevisiae. J Biol Chem (2003) 1.17
Role of Nox4 and p67phox subunit of Nox2 in ROS production in response to increased tubular flow in the mTAL of Dahl salt-sensitive rats. Am J Physiol Renal Physiol (2016) 0.75