Published in Epigenomics on January 01, 2014
Transgenerational programming of longevity and reproduction by post-eclosion dietary manipulation in Drosophila. Aging (Albany NY) (2016) 0.78
Disruption of Methionine Metabolism in Drosophila melanogaster Impacts Histone Methylation and Results in Loss of Viability. G3 (Bethesda) (2015) 0.78
Transcriptome Analysis of an Insecticide Resistant Housefly Strain: Insights about SNPs and Regulatory Elements in Cytochrome P450 Genes. PLoS One (2016) 0.77
Methyl-CpG binding domain proteins inhibit interspecies courtship and promote aggression in Drosophila. Sci Rep (2017) 0.75
DNA base modifications in honey bee and fruit fly genomes suggest an active demethylation machinery with species- and tissue-specific turnover rates. Biochem Biophys Rep (2016) 0.75
Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2. Science (2006) 3.87
Quantification of the sixth DNA base hydroxymethylcytosine in the brain. Angew Chem Int Ed Engl (2010) 3.50
DNA methylation in Drosophila melanogaster. Nature (2000) 3.46
The honey bee epigenomes: differential methylation of brain DNA in queens and workers. PLoS Biol (2010) 3.42
TETonic shift: biological roles of TET proteins in DNA demethylation and transcription. Nat Rev Mol Cell Biol (2013) 3.18
The ctenophore genome and the evolutionary origins of neural systems. Nature (2014) 2.96
DNA methylation is widespread and associated with differential gene expression in castes of the honeybee, Apis mellifera. Proc Natl Acad Sci U S A (2009) 2.77
Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis. Cell Rep (2013) 2.10
A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast. Hum Mol Genet (1998) 1.91
Retrotransposon silencing and telomere integrity in somatic cells of Drosophila depends on the cytosine-5 methyltransferase DNMT2. Nat Genet (2009) 1.78
A Dnmt2-like protein mediates DNA methylation in Drosophila. Development (2003) 1.61
Dnmt2-dependent methylomes lack defined DNA methylation patterns. Proc Natl Acad Sci U S A (2013) 1.43
Cytosine DNA methylation is found in Drosophila melanogaster but absent in Saccharomyces cerevisiae, Schizosaccharomyces pombe, and other yeast species. Anal Chem (2014) 1.23
Tet-mediated formation of 5-hydroxymethylcytosine in RNA. J Am Chem Soc (2014) 1.14
Genome methylation in D. melanogaster is found at specific short motifs and is independent of DNMT2 activity. Genome Res (2014) 1.12
The mysterious presence of a 5-methylcytosine oxidase in the Drosophila genome: possible explanations. Cell Cycle (2013) 0.93
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature (2011) 6.73
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine. Proc Natl Acad Sci U S A (2011) 5.45
Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine. Nucleic Acids Res (2010) 4.79
A human B cell methylome at 100-base pair resolution. Proc Natl Acad Sci U S A (2009) 4.72
MIRA-assisted microarray analysis, a new technology for the determination of DNA methylation patterns, identifies frequent methylation of homeodomain-containing genes in lung cancer cells. Cancer Res (2006) 3.66
Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay. Proc Natl Acad Sci U S A (2007) 2.91
Genomic mapping of 5-hydroxymethylcytosine in the human brain. Nucleic Acids Res (2011) 2.53
The RASSF proteins in cancer; from epigenetic silencing to functional characterization. Biochim Biophys Acta (2009) 2.50
5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations. Cancer Res (2011) 2.36
GADD45A does not promote DNA demethylation. PLoS Genet (2008) 2.36
A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication. Mol Cell (2008) 2.28
Methylated-CpG island recovery assay: a new technique for the rapid detection of methylated-CpG islands in cancer. Lab Invest (2005) 2.23
Repair of methylation damage in DNA and RNA by mammalian AlkB homologues. J Biol Chem (2005) 2.19
Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis. Cell Rep (2013) 2.10
High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer. Proc Natl Acad Sci U S A (2007) 2.10
The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells. J Biol Chem (2006) 2.10
Methylation of polycomb target genes in intestinal cancer is mediated by inflammation. Cancer Res (2008) 2.08
Tumor susceptibility of Rassf1a knockout mice. Cancer Res (2005) 2.03
Insulin gene expression is regulated by DNA methylation. PLoS One (2009) 1.97
The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1. Oncogene (2002) 1.96
RASSF1A is part of a complex similar to the Drosophila Hippo/Salvador/Lats tumor-suppressor network. Curr Biol (2007) 1.91
Short hairpin RNA-directed cytosine (CpG) methylation of the RASSF1A gene promoter in HeLa cells. Mol Ther (2005) 1.67
The tumor suppressor RASSF1A and MAP-1 link death receptor signaling to Bax conformational change and cell death. Mol Cell (2005) 1.58
CpG island hypermethylation in human astrocytomas. Cancer Res (2010) 1.57
Control of microtubule stability by the RASSF1A tumor suppressor. Oncogene (2003) 1.54
Relationship between gene body DNA methylation and intragenic H3K9me3 and H3K36me3 chromatin marks. PLoS One (2011) 1.50
Weak yet distinct mutagenicity of acrylamide in mammalian cells. J Natl Cancer Inst (2003) 1.48
Epigenetic inactivation of RAS association domain family protein 1 (RASSF1A) in malignant cutaneous melanoma. Cancer Res (2003) 1.48
Identification of driver and passenger DNA methylation in cancer by epigenomic analysis. Adv Genet (2010) 1.44
Frequent hypermethylation of MST1 and MST2 in soft tissue sarcoma. Mol Carcinog (2007) 1.44
Methylation of homeobox genes is a frequent and early epigenetic event in breast cancer. Breast Cancer Res (2009) 1.43
In vitro recapitulating of TP53 mutagenesis in hepatocellular carcinoma associated with dietary aflatoxin B1 exposure. Gastroenterology (2009) 1.43
MBD3L1 is a transcriptional repressor that interacts with methyl-CpG-binding protein 2 (MBD2) and components of the NuRD complex. J Biol Chem (2004) 1.41
The abnormal spindle-like, microcephaly-associated (ASPM) gene encodes a centrosomal protein. Cell Cycle (2005) 1.37
The MIRA method for DNA methylation analysis. Methods Mol Biol (2009) 1.35
DNA methylation biomarkers for lung cancer. Tumour Biol (2011) 1.35
Epigenetic control of female puberty. Nat Neurosci (2013) 1.34
DNA methylation profiling using the methylated-CpG island recovery assay (MIRA). Methods (2010) 1.30
Deleterious effects of endocrine disruptors are corrected in the mammalian germline by epigenome reprogramming. Genome Biol (2015) 1.30
RASSF3 and NORE1: identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1. Oncogene (2002) 1.29
Frequent epigenetic inactivation of the RASSF1A gene in hepatocellular carcinoma. Oncogene (2003) 1.27
Frequent hypermethylation of the RASSF1A gene in prostate cancer. Oncogene (2002) 1.23
Microcephalin encodes a centrosomal protein. Cell Cycle (2006) 1.21
Oxidative DNA damage induced by copper and hydrogen peroxide promotes CG-->TT tandem mutations at methylated CpG dinucleotides in nucleotide excision repair-deficient cells. Nucleic Acids Res (2002) 1.21
The role of DNA polymerase eta in UV mutational spectra. DNA Repair (Amst) (2005) 1.20
Second-hand smoke and human lung cancer. Lancet Oncol (2008) 1.17
Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma. Oncogene (2003) 1.15
DNA lesions induced by UV A1 and B radiation in human cells: comparative analyses in the overall genome and in the p53 tumor suppressor gene. Proc Natl Acad Sci U S A (2005) 1.15
Frequent epigenetic silencing of the CpG island promoter of RASSF1A in thyroid carcinoma. Cancer Res (2002) 1.15
Aging and DNA methylation. BMC Biol (2015) 1.15
A genome-wide screen identifies frequently methylated genes in haematological and epithelial cancers. Mol Cancer (2010) 1.14
Human thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair. Nucleic Acids Res (2003) 1.14
Tet-mediated formation of 5-hydroxymethylcytosine in RNA. J Am Chem Soc (2014) 1.14
The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death. J Biol Chem (2004) 1.13
Human RIF1 encodes an anti-apoptotic factor required for DNA repair. Carcinogenesis (2009) 1.12
Investigating human cancer etiology by DNA lesion footprinting and mutagenicity analysis. Carcinogenesis (2005) 1.11
Chromosome-wide analysis of parental allele-specific chromatin and DNA methylation. Mol Cell Biol (2011) 1.11
Protein phosphatase PP4 is overexpressed in human breast and lung tumors. Cell Res (2008) 1.10
A review of mechanisms of acrylamide carcinogenicity. Carcinogenesis (2007) 1.10
Translesion synthesis of 7,8-dihydro-8-oxo-2'-deoxyguanosine by DNA polymerase eta in vivo. Mutat Res (2008) 1.09
The tumor suppressor RASSF1A prevents dephosphorylation of the mammalian STE20-like kinases MST1 and MST2. J Biol Chem (2011) 1.09
Involvement of the RASSF1A tumor suppressor gene in controlling cell migration. Cancer Res (2005) 1.09
Epigenetic changes of DNA repair genes in cancer. J Mol Cell Biol (2011) 1.08
Deamination of 5-methylcytosines within cyclobutane pyrimidine dimers is an important component of UVB mutagenesis. J Biol Chem (2003) 1.08
CTCF-dependent chromatin bias constitutes transient epigenetic memory of the mother at the H19-Igf2 imprinting control region in prospermatogonia. PLoS Genet (2010) 1.07
Methylation of the retinoid response gene TIG1 in prostate cancer correlates with methylation of the retinoic acid receptor beta gene. Oncogene (2004) 1.07
Identification of 5 novel genes methylated in breast and other epithelial cancers. Mol Cancer (2010) 1.07
53BP1 is a positive regulator of the BRCA1 promoter. Cell Cycle (2005) 1.06
Genome-wide DNA methylation maps in follicular lymphoma cells determined by methylation-enriched bisulfite sequencing. PLoS One (2010) 1.06
G-to-T transversions and small tandem base deletions are the hallmark of mutations induced by ultraviolet a radiation in mammalian cells. Biochemistry (2004) 1.05
A methylation profile of in vitro immortalized human cell lines. Int J Oncol (2005) 1.04
Inactivation of RAS association domain family 1A gene in cervical carcinomas and the role of human papillomavirus infection. Cancer Res (2003) 1.04
MBD3L1 and MBD3L2, two new proteins homologous to the methyl-CpG-binding proteins MBD2 and MBD3: characterization of MBD3L1 as a testis-specific transcriptional repressor. Genomics (2002) 1.04
Fine tuning of globin gene expression by DNA methylation. PLoS One (2006) 1.04
Methods for genome-wide analysis of DNA methylation in intestinal tumors. Mutat Res (2009) 0.99
The role of DNA polymerase iota in UV mutational spectra. Mutat Res (2006) 0.99
Mutation accumulation in the intestine and colon of mice deficient in two intracellular glutathione peroxidases. Cancer Res (2006) 0.99
Fen1 mutations that specifically disrupt its interaction with PCNA cause aneuploidy-associated cancer. Cell Res (2011) 0.98
Parent-of-origin-specific binding of nuclear hormone receptor complexes in the H19-Igf2 imprinting control region. Mol Cell Biol (2004) 0.98
DNA damage, repair, and mutation induction by (+)-Syn and (-)-anti-dibenzo[a,l]pyrene-11,12-diol-13,14-epoxides in mouse cells. Cancer Res (2004) 0.98
Transcription-dependent cytosine deamination is a novel mechanism in ultraviolet light-induced mutagenesis. Curr Biol (2009) 0.98
Simulated sunlight and benzo[a]pyrene diol epoxide induced mutagenesis in the human p53 gene evaluated by the yeast functional assay: lack of correspondence to tumor mutation spectra. Carcinogenesis (2003) 0.96
Characterization of the 3' --> 5' exonuclease activity found in human nucleoside diphosphate kinase 1 (NDK1) and several of its homologues. Biochemistry (2005) 0.96
MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing. J Biol Chem (2005) 0.95
Polyploid cells rewire DNA damage response networks to overcome replication stress-induced barriers for tumour progression. Nat Commun (2012) 0.95
Applications of the human p53 knock-in (Hupki) mouse model for human carcinogen testing. FASEB J (2010) 0.94
Riboflavin activated by ultraviolet A1 irradiation induces oxidative DNA damage-mediated mutations inhibited by vitamin C. Proc Natl Acad Sci U S A (2007) 0.94
Effects of endocrine disruptors on imprinted gene expression in the mouse embryo. Epigenetics (2011) 0.93
The mysterious presence of a 5-methylcytosine oxidase in the Drosophila genome: possible explanations. Cell Cycle (2013) 0.93
Tumor suppressor Ras-association domain family 1 isoform A is a novel regulator of cardiac hypertrophy. Circulation (2009) 0.92
Rapid repair of UVA-induced oxidized purines and persistence of UVB-induced dipyrimidine lesions determine the mutagenicity of sunlight in mouse cells. FASEB J (2008) 0.91
Haploid male germ cell- and oocyte-specific Mbd3l1 and Mbd3l2 genes are dispensable for early development, fertility, and zygotic DNA demethylation in the mouse. Dev Dyn (2008) 0.90
Lack of mutagenicity of acrolein-induced DNA adducts in mouse and human cells. Cancer Res (2007) 0.90
Similar mutagenicity of photoactivated porphyrins and ultraviolet A radiation in mouse embryonic fibroblasts: involvement of oxidative DNA lesions in mutagenesis. Biochemistry (2004) 0.88
CDK5RAP2 is required for spindle checkpoint function. Cell Cycle (2009) 0.88
In vivo assays for transcription-coupled repair. Methods Enzymol (2006) 0.88
Genotoxicity of acrylamide and glycidamide. J Natl Cancer Inst (2004) 0.87
Peroxyl radical mediated oxidative DNA base damage: implications for lipid peroxidation induced mutagenesis. Biochemistry (2004) 0.87