Published in Methods on November 06, 2014
Developmental enhancers revealed by extensive DNA methylome maps of zebrafish early embryos. Nat Commun (2015) 0.95
Induction of hematopoietic and endothelial cell program orchestrated by ETS transcription factor ER71/ETV2. EMBO Rep (2015) 0.94
Mapping of Variable DNA Methylation Across Multiple Cell Types Defines a Dynamic Regulatory Landscape of the Human Genome. G3 (Bethesda) (2016) 0.80
Statistical challenges in analyzing methylation and long-range chromosomal interaction data. Stat Biosci (2016) 0.79
Profiling genome-wide DNA methylation. Epigenetics Chromatin (2016) 0.79
Inhibition of DNA Methyltransferases Blocks Mutant Huntingtin-Induced Neurotoxicity. Sci Rep (2016) 0.79
Differential Methylation of Genomic Regions Associated with Heteroblasty Detected by M&M Algorithm in the Nonmodel Species Eucalyptus globulus Labill. Int J Genomics (2016) 0.76
Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation. BMC Genomics (2017) 0.76
Genome-Wide Epigenetic Studies in Human Disease: A Primer on -Omic Technologies. Am J Epidemiol (2015) 0.75
Whole-Genome DNA Methylation Profiling Identifies Epigenetic Signatures of Uterine Carcinosarcoma. Neoplasia (2017) 0.75
How to Isolate a Plant's Hypomethylome in One Shot. Biomed Res Int (2015) 0.75
Comparative analysis of MBD-seq and MeDIP-seq and estimation of gene expression changes in a rodent model of schizophrenia. Genomics (2017) 0.75
Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics (2009) 190.94
Human DNA methylomes at base resolution show widespread epigenomic differences. Nature (2009) 34.27
DNA methylation patterns and epigenetic memory. Genes Dev (2002) 33.83
Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature (2008) 30.29
Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning. Nature (2008) 26.78
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet (2009) 18.90
A large genome center's improvements to the Illumina sequencing system. Nat Methods (2008) 15.56
Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nat Genet (2005) 15.37
Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat Rev Genet (2012) 15.21
DNA methylation and human disease. Nat Rev Genet (2005) 12.00
Principles and challenges of genomewide DNA methylation analysis. Nat Rev Genet (2010) 10.71
Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature (2010) 9.81
DNA-binding factors shape the mouse methylome at distal regulatory regions. Nature (2011) 8.75
Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis. Nucleic Acids Res (2005) 8.69
Genome-wide evolutionary analysis of eukaryotic DNA methylation. Science (2010) 8.46
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proc Natl Acad Sci U S A (2000) 8.12
Conservation and divergence of methylation patterning in plants and animals. Proc Natl Acad Sci U S A (2010) 7.30
Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome. Cell (2012) 7.09
Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications. Nat Biotechnol (2010) 7.00
Quantitative comparison of genome-wide DNA methylation mapping technologies. Nat Biotechnol (2010) 5.96
Charting a dynamic DNA methylation landscape of the human genome. Nature (2013) 5.80
Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution. Science (2012) 5.17
Microarray-based DNA methylation profiling: technology and applications. Nucleic Acids Res (2006) 3.73
MBD-isolated Genome Sequencing provides a high-throughput and comprehensive survey of DNA methylation in the human genome. Nucleic Acids Res (2009) 3.29
The Human Epigenome Browser at Washington University. Nat Methods (2011) 2.62
DNA methylation dynamics in health and disease. Nat Struct Mol Biol (2013) 2.58
Epigenetic memory at embryonic enhancers identified in DNA methylation maps from adult mouse tissues. Nat Genet (2013) 2.41
MEDME: an experimental and analytical methodology for the estimation of DNA methylation levels based on microarray derived MeDIP-enrichment. Genome Res (2008) 2.28
Chromatin and sequence features that define the fine and gross structure of genomic methylation patterns. Genome Res (2010) 2.25
Methylated-CpG island recovery assay: a new technique for the rapid detection of methylated-CpG islands in cancer. Lab Invest (2005) 2.23
Evaluation of affinity-based genome-wide DNA methylation data: effects of CpG density, amplification bias, and copy number variation. Genome Res (2010) 1.77
Comparison of methyl-DNA immunoprecipitation (MeDIP) and methyl-CpG binding domain (MBD) protein capture for genome-wide DNA methylation analysis reveal CpG sequence coverage bias. Epigenetics (2011) 1.76
Methylome analysis using MeDIP-seq with low DNA concentrations. Nat Protoc (2012) 1.70
DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape. Nat Genet (2013) 1.64
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm. Genome Res (2013) 1.33
Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods. Genome Res (2013) 1.31
The role of gene DCDC2 in German dyslexics. Ann Dyslexia (2009) 1.20
De novo DNA demethylation and noncoding transcription define active intergenic regulatory elements. Genome Res (2013) 1.00
Evidence for non-CpG methylation in mammals. Exp Cell Res (2011) 0.94
DNA unmethylome profiling by covalent capture of CpG sites. Nat Commun (2013) 0.91
methylC Track: visual integration of single-base resolution DNA methylation data on the WashU EpiGenome Browser. Bioinformatics (2014) 0.84
Principles of regulatory information conservation between mouse and human. Nature (2014) 1.34