Published in Nature on December 03, 2014
Deep sequencing of 10,000 human genomes. Proc Natl Acad Sci U S A (2016) 1.72
A reference panel of 64,976 haplotypes for genotype imputation. Nat Genet (2016) 1.61
Fast Principal-Component Analysis Reveals Convergent Evolution of ADH1B in Europe and East Asia. Am J Hum Genet (2016) 1.53
The future of genomic medicine education in Africa. Genome Med (2015) 1.44
A genomic portrait of haplotype diversity and signatures of selection in indigenous southern African populations. PLoS Genet (2015) 1.43
H3ABioNet, a sustainable pan-African bioinformatics network for human heredity and health in Africa. Genome Res (2015) 1.39
Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells. Cell (2016) 1.10
"Broadband" Bioinformatics Skills Transfer with the Knowledge Transfer Programme (KTP): Educational Model for Upliftment and Sustainable Development. PLoS Comput Biol (2015) 1.07
A novel locus of resistance to severe malaria in a region of ancient balancing selection. Nature (2015) 1.03
Translational Genomics in Low- and Middle-Income Countries: Opportunities and Challenges. Public Health Genomics (2015) 0.93
Microbial metaproteomics for characterizing the range of metabolic functions and activities of human gut microbiota. Proteomics (2015) 0.92
Motor Neuron Diseases in Sub-Saharan Africa: The Need for More Population-Based Studies. Biomed Res Int (2015) 0.90
Searching for the human genetic factors standing in the way of universally effective vaccines. Philos Trans R Soc Lond B Biol Sci (2015) 0.90
Neurogenomics: An opportunity to integrate neuroscience, genomics and bioinformatics research in Africa. Appl Transl Genom (2015) 0.90
Trans-ethnic study design approaches for fine-mapping. Eur J Hum Genet (2016) 0.89
Japonica array: improved genotype imputation by designing a population-specific SNP array with 1070 Japanese individuals. J Hum Genet (2015) 0.89
60,000 years of interactions between Central and Eastern Africa documented by major African mitochondrial haplogroup L2. Sci Rep (2015) 0.84
Neurogenomics: Challenges and opportunities for Ghana. Appl Transl Genom (2015) 0.83
Are There Clinical Implications of Racial Differences in HbA1c? Yes, to Not Consider Can Do Great Harm! Diabetes Care (2016) 0.82
Stroke genomics in people of African ancestry: charting new paths. Cardiovasc J Afr (2015) 0.81
Success stories in genomic medicine from resource-limited countries. Hum Genomics (2015) 0.81
Detecting Genomic Signatures of Natural Selection with Principal Component Analysis: Application to the 1000 Genomes Data. Mol Biol Evol (2015) 0.81
Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population. PLoS Genet (2015) 0.81
Population genetics: the African Genome Variation Project. Nat Rev Genet (2014) 0.80
Genome Data Exploration Using Correspondence Analysis. Bioinform Biol Insights (2016) 0.79
Whole genome sequences are required to fully resolve the linkage disequilibrium structure of human populations. BMC Genomics (2015) 0.79
Conjunctival fibrosis and the innate barriers to Chlamydia trachomatis intracellular infection: a genome wide association study. Sci Rep (2015) 0.79
Recent advances in malaria genomics and epigenomics. Genome Med (2016) 0.79
Tracing the peopling of the world through genomics. Nature (2017) 0.79
Chad Genetic Diversity Reveals an African History Marked by Multiple Holocene Eurasian Migrations. Am J Hum Genet (2016) 0.79
Diversity and inclusion in genomic research: why the uneven progress? J Community Genet (2017) 0.79
Neurogenomics in Africa: Perspectives, progress, possibilities and priorities. J Neurol Sci (2016) 0.78
Pharmacogenomic implications of the evolutionary history of infectious diseases in Africa. Pharmacogenomics J (2016) 0.78
Whole genome characterization of sequence diversity of 15,220 Icelanders. Sci Data (2017) 0.77
Global diversity in the TAS2R38 bitter taste receptor: revisiting a classic evolutionary PROPosal. Sci Rep (2016) 0.77
Admixture into and within sub-Saharan Africa. Elife (2016) 0.77
Extensive Admixture and Selective Pressure Across the Sahel Belt. Genome Biol Evol (2015) 0.77
H3Africa comes of age. Cardiovasc J Afr (2015) 0.76
Sickle cell disease and H3Africa: enhancing genomic research on cardiovascular diseases in African patients. Cardiovasc J Afr (2015) 0.76
Complex Ancient Genetic Structure and Cultural Transitions in Southern African Populations. Genetics (2016) 0.76
Cystic fibrosis on the African continent. Genet Med (2015) 0.76
Human Knockout Carriers: Dead, Diseased, Healthy, or Improved? Trends Mol Med (2016) 0.76
Mapping the genetic diversity of HLA haplotypes in the Japanese populations. Sci Rep (2015) 0.76
Inferences of African evolutionary history from genomic data. Curr Opin Genet Dev (2016) 0.76
Hunter-gatherer genomics: evolutionary insights and ethical considerations. Curr Opin Genet Dev (2016) 0.75
Small Traditional Human Communities Sustain Genomic Diversity over Microgeographic Scales despite Linguistic Isolation. Mol Biol Evol (2016) 0.75
Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels. J Med Genet (2016) 0.75
Variation in NAT2 acetylation phenotypes is associated with differences in food-producing subsistence modes and ecoregions in Africa. BMC Evol Biol (2015) 0.75
Differential frequency of NKG2C/KLRC2 deletion in distinct African populations and susceptibility to Trachoma: a new method for imputation of KLRC2 genotypes from SNP genotyping data. Hum Genet (2016) 0.75
Trans-ethnic follow-up of breast cancer GWAS hits using the preferential linkage disequilibrium approach. Oncotarget (2016) 0.75
Molecular Diagnosis of Inherited Retinal Diseases in Indigenous African Populations by Whole-Exome Sequencing. Invest Ophthalmol Vis Sci (2016) 0.75
The impact of rare and low-frequency genetic variants in common disease. Genome Biol (2017) 0.75
Large Scale Genetic Research on Neuropsychiatric Disorders in African Populations is Needed. EBioMedicine (2015) 0.75
Genomics: African dawn. Nature (2014) 0.75
Genome-wide Analysis in Brazilians Reveals Highly Differentiated Native American Genome Regions. Mol Biol Evol (2017) 0.75
Human Leukocyte Antigen Diversity: A Southern African Perspective. J Immunol Res (2015) 0.75
Exome-based Variant Detection in Core Promoters. Sci Rep (2016) 0.75
Novel mutation in the CHST6 gene causes macular corneal dystrophy in a black South African family. BMC Med Genet (2016) 0.75
African Genetic Diversity: Implications for Cytochrome P450-mediated Drug Metabolism and Drug Development. EBioMedicine (2017) 0.75
Population Structure of UK Biobank and Ancient Eurasians Reveals Adaptation at Genes Influencing Blood Pressure. Am J Hum Genet (2016) 0.75
Human ancestry correlates with language and reveals that race is not an objective genomic classifier. Sci Rep (2017) 0.75
Next Generation Sequencing Reveals High Prevalence of BRCA1 and BRCA2 Variants of Unknown Significance in Early-Onset Breast Cancer in African American Women. Ethn Dis (2017) 0.75
The African diaspora: history, adaptation and health. Curr Opin Genet Dev (2016) 0.75
Genetic discovery in multi-ethnic populations. Eur J Hum Genet (2016) 0.75
Global Carrier Rates of Rare Inherited Disorders Using Population Exome Sequences. PLoS One (2016) 0.75
Three-dimensional retinal organoids from mouse pluripotent stem cells mimic in vivo development with enhanced stratification and rod photoreceptor differentiation. Mol Vis (2016) 0.75
Population genetic analysis of the DARC locus (Duffy) reveals adaptation from standing variation associated with malaria resistance in humans. PLoS Genet (2017) 0.75
The role of natural selection in human evolution - insights from Latin America. Genet Mol Biol (2016) 0.75
Population structure and infectious disease risk in southern Africa. Mol Genet Genomics (2017) 0.75
Replication and fine-mapping of genetic predictors of lipid traits in African-Americans. J Hum Genet (2017) 0.75
Northeast African genomic variation shaped by the continuity of indigenous groups and Eurasian migrations. PLoS Genet (2017) 0.75
Clinical and Genetic Characteristics of Leukodystrophies in Africa. J Neurosci Rural Pract (2017) 0.75
Differential analysis between somatic mutation and germline variation profiles reveals cancer-related genes. Genome Med (2017) 0.75
Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. Am J Hum Genet (2017) 0.75
Genetics of HIV-associated sensory neuropathy and related pain in Africans. J Neurovirol (2017) 0.75
Establishing multiple omics baselines for three Southeast Asian populations in the Singapore Integrative Omics Study. Nat Commun (2017) 0.75
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An integrated map of genetic variation from 1,092 human genomes. Nature (2012) 59.82
A map of recent positive selection in the human genome. PLoS Biol (2006) 29.19
Fast model-based estimation of ancestry in unrelated individuals. Genome Res (2009) 15.63
Genome-wide association study of blood pressure and hypertension. Nat Genet (2009) 11.54
The genetic structure and history of Africans and African Americans. Science (2009) 10.65
Siglecs and their roles in the immune system. Nat Rev Immunol (2007) 7.98
The complete genome sequence of a Neanderthal from the Altai Mountains. Nature (2013) 6.10
Ancient admixture in human history. Genetics (2012) 4.99
Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet (2009) 4.30
Research capacity. Enabling the genomic revolution in Africa. Science (2014) 3.05
Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension. Nat Genet (2013) 2.83
Climate-controlled Holocene occupation in the Sahara: motor of Africa's evolution. Science (2006) 2.68
Genetic evidence for the convergent evolution of light skin in Europeans and East Asians. Mol Biol Evol (2006) 2.54
Extremely low-coverage sequencing and imputation increases power for genome-wide association studies. Nat Genet (2012) 2.50
Differential susceptibility to hypertension is due to selection during the out-of-Africa expansion. PLoS Genet (2005) 2.33
Genomic variation in seven Khoe-San groups reveals adaptation and complex African history. Science (2012) 1.99
Population genetics of malaria resistance in humans. Heredity (Edinb) (2011) 1.85
Ancient west Eurasian ancestry in southern and eastern Africa. Proc Natl Acad Sci U S A (2014) 1.79
Gene flow from North Africa contributes to differential human genetic diversity in southern Europe. Proc Natl Acad Sci U S A (2013) 1.77
Lakeside cemeteries in the Sahara: 5000 years of holocene population and environmental change. PLoS One (2008) 1.62
Ethiopian genetic diversity reveals linguistic stratification and complex influences on the Ethiopian gene pool. Am J Hum Genet (2012) 1.60
Genome-wide comparisons of variation in linkage disequilibrium. Genome Res (2009) 1.43
Identifying Darwinian selection acting on different human APOL1 variants among diverse African populations. Am J Hum Genet (2013) 1.35
Patterns of ancestry, signatures of natural selection, and genetic association with stature in Western African pygmies. PLoS Genet (2012) 1.33
Analysis of IL10 haplotypic associations with severe malaria. Genes Immun (2005) 1.29
Bringing together linguistic and genetic evidence to test the Bantu expansion. Proc Biol Sci (2012) 1.27
Common variants in the ATP2B1 gene are associated with susceptibility to hypertension: the Japanese Millennium Genome Project. Hypertension (2010) 1.26
Imputation-based meta-analysis of severe malaria in three African populations. PLoS Genet (2013) 1.25
Identification of cell surface molecules involved in dystroglycan-independent Lassa virus cell entry. J Virol (2011) 1.23
Genome-wide scans provide evidence for positive selection of genes implicated in Lassa fever. Philos Trans R Soc Lond B Biol Sci (2012) 1.23
Association of the OCA2 polymorphism His615Arg with melanin content in east Asian populations: further evidence of convergent evolution of skin pigmentation. PLoS Genet (2010) 1.17
Genetic variations in ATP2B1, CSK, ARSG and CSMD1 loci are related to blood pressure and/or hypertension in two Korean cohorts. J Hum Hypertens (2009) 1.10
Candidate malaria susceptibility/protective SNPs in hospital and population-based studies: the effect of sub-structuring. Malar J (2010) 1.09
Increased susceptibility of Fas ligand-deficient gld mice to Trypanosoma cruzi infection due to a Th2-biased host immune response. Eur J Immunol (1999) 1.07
Human conjunctival transcriptome analysis reveals the prominence of innate defense in Chlamydia trachomatis infection. Infect Immun (2010) 1.07
Population genetics of IFIH1: ancient population structure, local selection, and implications for susceptibility to type 1 diabetes. Mol Biol Evol (2010) 1.05
Murine malaria is exacerbated by CTLA-4 blockade. J Immunol (2002) 1.04
Host HDL biogenesis machinery is recruited to the inclusion of Chlamydia trachomatis-infected cells and regulates chlamydial growth. Cell Microbiol (2012) 1.03
Levels of soluble CD163 and severity of malaria in children in Ghana. Clin Vaccine Immunol (2008) 1.02
Interleukin-10 (IL-10) polymorphisms are associated with IL-10 production and clinical malaria in young children. Infect Immun (2012) 0.99
The impact of agricultural emergence on the genetic history of African rainforest hunter-gatherers and agriculturalists. Nat Commun (2014) 0.98
Fas-FasL interaction modulates nitric oxide production in Trypanosoma cruzi-infected mice. Immunology (2001) 0.91
Complement receptor 1 variants confer protection from severe malaria in Odisha, India. PLoS One (2012) 0.89
Trypanosomiasis-induced Th17-like immune responses in carp. PLoS One (2010) 0.85
Abnormal increase in urinary aquaporin-2 excretion in response to hypertonic saline in essential hypertension. BMC Nephrol (2012) 0.84
Evidence for malaria selection of a CR1 haplotype in Sardinia. Genes Immun (2011) 0.83
Malaria: looking for selection signatures in the human PKLR gene region. Br J Haematol (2010) 0.82