Mesenchymal stem cells promote liver regeneration and prolong survival in small-for-size liver grafts: involvement of C-Jun N-terminal kinase, cyclin D1, and NF-κB.

PubWeight™: 0.90‹?›

🔗 View Article (PMC 4257551)

Published in PLoS One on December 05, 2014

Authors

Weijie Wang1, Zhiyong Du2, Jiqi Yan3, Di Ma3, Minmin Shi3, Mingjun Zhang3, Chenghong Peng3, Hongwei Li3

Author Affiliations

1: Department of Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China; Department of Surgery, First Affiliated Hospital of Zhengzhou University, Zhengzhou University School of Medicine, Zhengzhou, Henan Province, China.
2: Department of Hepatobiliary Surgery, Central Hospital of Wuhan, Wuhan, Hubei Province, China.
3: Department of Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Articles cited by this

In vitro hepatic differentiation of human mesenchymal stem cells. Hepatology (2004) 4.36

Mechanisms of Liver Injury. I. TNF-alpha-induced liver injury: role of IKK, JNK, and ROS pathways. Am J Physiol Gastrointest Liver Physiol (2006) 3.16

Mesenchymal stem cell-derived molecules directly modulate hepatocellular death and regeneration in vitro and in vivo. Hepatology (2008) 2.50

A surgical experience with five hundred thirty liver transplants in the rat. Surgery (1983) 2.48

Stem cell therapy for liver disease: parameters governing the success of using bone marrow mesenchymal stem cells. Gastroenterology (2008) 2.31

Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver. EMBO J (2002) 2.15

Functional integration of hepatocytes derived from human mesenchymal stem cells into mouse livers. Gut (2006) 1.96

c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration. Hepatology (2003) 1.87

Mesenchymal stem cell-conditioned medium reduces liver injury and enhances regeneration in reduced-size rat liver transplantation. J Surg Res (2013) 1.62

Role of splanchnic hemodynamics in liver regeneration after living donor liver transplantation. Liver Transpl (2009) 1.53

Bone marrow-derived mesenchymal stem cells ameliorate hepatic ischemia reperfusion injury in a rat model. PLoS One (2011) 1.43

Interleukin-6 inhibits oxidative injury and necrosis after extreme liver resection. Hepatology (2007) 1.20

Intravenous injection of mesenchymal stem cells is effective in treating liver fibrosis. World J Gastroenterol (2012) 1.18

Mesenchymal stem cell infusion therapy in a carbon tetrachloride-induced liver fibrosis model affects matrix metalloproteinase expression. Cell Biol Int (2010) 1.16

The generation of hepatocytes from mesenchymal stem cells and engraftment into murine liver. Nat Protoc (2010) 1.14

Hepatic potential of bone marrow stromal cells: development of in vitro co-culture and intra-portal transplantation models. J Immunol Methods (2005) 1.14

Liver regeneration is suppressed in small-for-size liver grafts after transplantation: involvement of c-Jun N-terminal kinase, cyclin D1, and defective energy supply. Transplantation (2006) 1.11

The molecular physiology of liver regeneration following partial hepatectomy. Liver Int (2003) 1.10

IFN-gamma-inducible protein-10 (CXCL10) is hepatoprotective during acute liver injury through the induction of CXCR2 on hepatocytes. J Immunol (2001) 1.09

Therapeutic implications of mesenchymal stem cells in liver injury. J Biomed Biotechnol (2011) 1.02

Transplantation of mesenchymal stem cells for the treatment of liver diseases, is there enough evidence? Stem Cell Res (2013) 1.00

Adipose tissue-derived mesenchymal stem cell transplantation promotes hepatic regeneration after hepatic ischemia-reperfusion and subsequent hepatectomy in rats. J Surg Res (2012) 0.98

Efficacy of adipose tissue-mesenchymal stem cell transplantation in rats with acetaminophen liver injury. Stem Cell Res (2013) 0.97

Efficacy of adipose tissue-derived mesenchymal stem cells for fulminant hepatitis in mice induced by concanavalin A. J Gastroenterol Hepatol (2012) 0.94

Mesenchymal stem cells over-expressing hepatocyte growth factor improve small-for-size liver grafts regeneration. Mol Ther (2007) 0.93

Principles and problems of the electrophoretic mobility shift assay. J Pharmacol Toxicol Methods (2010) 0.93

Secreted factors of human liver-derived mesenchymal stem cells promote liver regeneration early after partial hepatectomy. Stem Cells Dev (2012) 0.93

Transplantation of bone marrow-derived mesenchymal stem cells after regional hepatic irradiation ameliorates thioacetamide-induced liver fibrosis in rats. J Surg Res (2013) 0.92

Antifibrotic effect of hepatocyte growth factor-expressing mesenchymal stem cells in small-for-size liver transplant rats. Stem Cells Dev (2010) 0.92

Bone marrow mesenchymal stem cells ameliorate hepatic ischemia/reperfusion injuries via inactivation of the MEK/ERK signaling pathway in rats. J Surg Res (2012) 0.90

NF-κB essential modifier is required for hepatocyte proliferation and the oval cell reaction after partial hepatectomy in mice. Gastroenterology (2012) 0.90

Mechanisms of interleukin-6 protection against ischemia-reperfusion injury in rat liver. Cytokine (2006) 0.89

Living donor liver transplantation. Curr Opin Organ Transplant (2010) 0.85

Rapamycin ameliorates inflammation and fibrosis in the early phase of cirrhotic portal hypertension in rats through inhibition of mTORC1 but not mTORC2. PLoS One (2014) 0.85

Mobilization of hepatic mesenchymal stem cells from human liver grafts. Liver Transpl (2011) 0.84

Implanted adipose-derived stem cells attenuate small-for-size liver graft injury by secretion of VEGF in rats. Am J Transplant (2011) 0.84

Prevention of acute liver allograft rejection by IL-10-engineered mesenchymal stem cells. Clin Exp Immunol (2014) 0.83

IP-10 protects while MIP-2 promotes experimental anesthetic hapten - induced hepatitis. J Autoimmun (2009) 0.82

Role of stem cells in repair of liver injury: experimental and clinical benefit of transferred stem cells on liver failure. World J Gastroenterol (2013) 0.82

Antiinflammatory properties of IL-10 rescue small-for-size liver grafts. Liver Transpl (2007) 0.82

Split liver transplantation. Transplant Proc (2011) 0.82

Suppression of liver regeneration affects hepatic graft survival in small-for-size liver transplantation in rats. Hepatol Res (2012) 0.81

Mesenchymal stem cells administered after liver transplantation prevent acute graft-versus-host disease in rats. Liver Transpl (2012) 0.79

In vitro hepatic trans-differentiation of human mesenchymal stem cells using sera from congestive/ischemic liver during cardiac failure. PLoS One (2014) 0.79

Bone marrow-derived mesenchymal stem cells as immunosuppressants in liver transplantation: a review of current data. Transfus Med Rev (2011) 0.78