Published in Cell on September 22, 1989
Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15. EMBO J (1994) 5.69
Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family. Proc Natl Acad Sci U S A (1991) 3.31
The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains. Mol Cell Biol (1991) 2.77
Homodimerization and constitutive activation of the erythropoietin receptor. Proc Natl Acad Sci U S A (1992) 2.29
Friend spleen focus-forming virus glycoprotein gp55 interacts with the erythropoietin receptor in the endoplasmic reticulum and affects receptor metabolism. Proc Natl Acad Sci U S A (1990) 2.23
Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily. J Exp Med (1990) 2.12
Molecular cloning and expression of the murine interleukin-5 receptor. EMBO J (1990) 1.85
Structure and transcription of the mouse erythropoietin receptor gene. Mol Cell Biol (1990) 1.57
Association of p56lck with IL-2 receptor beta chain is critical for the IL-2-induced activation of p56lck. EMBO J (1993) 1.48
Expression of a functional c-kit receptor on a subset of natural killer cells. J Exp Med (1993) 1.45
Mechanism of leukemogenesis induced by mink cell focus-forming murine leukemia viruses. J Virol (1991) 1.44
Interleukin 2 and erythropoietin activate STAT5/MGF via distinct pathways. EMBO J (1995) 1.42
Murine interleukin 2 receptor beta chain: dysregulated gene expression in lymphoma line EL-4 caused by a promoter insertion. Proc Natl Acad Sci U S A (1990) 1.42
In vitro phosphorylation of the erythropoietin receptor and an associated protein, pp130. Mol Cell Biol (1992) 1.40
Molecular cloning and expression of the human interleukin 5 receptor. J Exp Med (1992) 1.31
The erythropoietin receptor transmembrane region is necessary for activation by the Friend spleen focus-forming virus gp55 glycoprotein. Mol Cell Biol (1992) 1.30
c-fps/fes protein-tyrosine kinase is implicated in a signaling pathway triggered by granulocyte-macrophage colony-stimulating factor and interleukin-3. EMBO J (1993) 1.29
Ligand-induced activation of chimeric receptors between the erythropoietin receptor and receptor tyrosine kinases. Proc Natl Acad Sci U S A (1994) 1.23
c-fos gene induction by interleukin 2: identification of the critical cytoplasmic regions within the interleukin 2 receptor beta chain. Proc Natl Acad Sci U S A (1992) 1.23
Localized cytosolic domains of the erythropoietin receptor regulate growth signaling and down-modulate responsiveness to granulocyte-macrophage colony-stimulating factor. Proc Natl Acad Sci U S A (1991) 1.23
Isolation of interleukin 2-induced immediate-early genes. Proc Natl Acad Sci U S A (1993) 1.23
Antisense oligonucleotides from the stage-specific myeloid zinc finger gene MZF-1 inhibit granulopoiesis in vitro. J Exp Med (1991) 1.17
Erythropoietin receptor signals both proliferation and erythroid-specific differentiation. Proc Natl Acad Sci U S A (1993) 1.10
Increased cell surface expression and enhanced folding in the endoplasmic reticulum of a mutant erythropoietin receptor. Proc Natl Acad Sci U S A (1995) 1.05
Erythropoietin receptor. Subunit structure and activation. J Clin Invest (1990) 1.05
Positive receptor feedback during lineage commitment can generate ultrasensitivity to ligand and confer robustness to a bistable switch. Biophys J (2008) 0.97
Functional murine interleukin 6 receptor with the intracisternal A particle gene product at its cytoplasmic domain. Its possible role in plasmacytomagenesis. J Exp Med (1990) 0.95
A functional isoform of the human granulocyte/macrophage colony-stimulating factor receptor has an unusual cytoplasmic domain. Proc Natl Acad Sci U S A (1991) 0.94
Mutations in the WSAWSE and cytosolic domains of the erythropoietin receptor affect signal transduction and ligand binding and internalization. Mol Cell Biol (1992) 0.92
Fusion of the erythropoietin receptor and the Friend spleen focus-forming virus gp55 glycoprotein transforms a factor-dependent hematopoietic cell line. Mol Cell Biol (1993) 0.91
Activation of the prolactin receptor gene by promoter insertion in a Moloney murine leukemia virus-induced rat thymoma. J Virol (1992) 0.90
Distinct downstream signaling mechanism between erythropoietin receptor and interleukin-2 receptor. EMBO J (1992) 0.90
Relaxin binding in the rat heart atrium. Proc Natl Acad Sci U S A (1992) 0.89
The human interleukin-2 receptor beta-chain gene: genomic organization, promoter analysis and chromosomal assignment. Nucleic Acids Res (1990) 0.89
Constitutive and impaired signaling of leptin receptors containing the Gln --> Pro extracellular domain fatty mutation. Proc Natl Acad Sci U S A (1997) 0.88
Erythropoietin and interleukin-2 activate distinct JAK kinase family members. Mol Cell Biol (1994) 0.87
The human granulocyte-macrophage colony-stimulating factor receptor is capable of initiating signal transduction in NIH3T3 cells. EMBO J (1993) 0.87
Cell surface activation of the erythropoietin receptor by Friend spleen focus-forming virus gp55. J Virol (1995) 0.86
Cellular signalling mechanisms in B lymphocytes. Biochem J (1993) 0.84
Characterization of a tyrosine kinase activity associated with the high-affinity interleukin 2 receptor complex. Biochem J (1992) 0.83
Progress in detecting cell-surface protein receptors: the erythropoietin receptor example. Ann Hematol (2013) 0.81
Origin and rapid evolution of a novel murine erythroleukemia virus of the spleen focus-forming virus family. J Virol (1998) 0.76
Cloning expeditions: risky but rewarding. Mol Cell Biol (2013) 0.75
Specific inhibition of interleukin 3 bioactivity by a monoclonal antibody reactive with hematopoietic progenitor cells. Proc Natl Acad Sci U S A (1990) 0.75
Prediction of the secondary structure of proteins from their amino acid sequence. Adv Enzymol Relat Areas Mol Biol (1978) 29.77
Empirical predictions of protein conformation. Annu Rev Biochem (1978) 25.48
Prediction of protein conformation. Biochemistry (1974) 20.51
Conformational parameters for amino acids in helical, beta-sheet, and random coil regions calculated from proteins. Biochemistry (1974) 12.07
Computed circular dichroism spectra for the evaluation of protein conformation. Biochemistry (1969) 10.58
Role of transforming growth factor beta in human disease. N Engl J Med (2000) 10.17
A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem (1995) 9.72
pH and the recycling of transferrin during receptor-mediated endocytosis. Proc Natl Acad Sci U S A (1983) 8.41
Sequence and structure of a human glucose transporter. Science (1985) 8.03
Synchronised transmembrane insertion and glycosylation of a nascent membrane protein. Nature (1977) 7.72
Multiple mechanisms of protein insertion into and across membranes. Science (1985) 7.70
Oxidized redox state of glutathione in the endoplasmic reticulum. Science (1992) 6.91
Intracellular site of asialoglycoprotein receptor-ligand uncoupling: double-label immunoelectron microscopy during receptor-mediated endocytosis. Cell (1983) 6.89
Ineffective erythropoiesis in Stat5a(-/-)5b(-/-) mice due to decreased survival of early erythroblasts. Blood (2001) 6.35
Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci U S A (2001) 6.20
Membrane assembly in vitro: synthesis, glycosylation, and asymmetric insertion of a transmembrane protein. Proc Natl Acad Sci U S A (1977) 5.51
Oligomerization is essential for transport of vesicular stomatitis viral glycoprotein to the cell surface. Cell (1986) 5.19
Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and beta-pancreatic islet cells. Cell (1988) 5.18
Predicting the orientation of eukaryotic membrane-spanning proteins. Proc Natl Acad Sci U S A (1989) 5.15
Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell (1995) 4.73
Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction. Cell (1999) 4.69
Expression cloning of the TGF-beta type II receptor, a functional transmembrane serine/threonine kinase. Cell (1992) 4.68
Expression cloning of the murine erythropoietin receptor. Cell (1989) 4.59
Activation of cell growth by binding of Friend spleen focus-forming virus gp55 glycoprotein to the erythropoietin receptor. Nature (1990) 4.59
Kinetics of internalization and recycling of transferrin and the transferrin receptor in a human hepatoma cell line. Effect of lysosomotropic agents. J Biol Chem (1983) 4.55
A signal sequence for the insertion of a transmembrane glycoprotein. Similarities to the signals of secretory proteins in primary structure and function. J Biol Chem (1978) 4.43
Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein. Cell (1994) 4.33
Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. Cell (1995) 4.32
Intracellular transport of secretory and membrane proteins in hepatoma cells infected by vesicular stomatitis virus. Cell (1980) 4.15
Hepatoma secretory proteins migrate from rough endoplasmic reticulum to Golgi at characteristic rates. Nature (1983) 4.12
Separate pathways of maturation of the major structural proteins of vesicular stomatitis virus. J Virol (1977) 4.03
Initiation of haemoglobin synthesis by methionyl-tRNA. Nature (1970) 3.99
Translational control of protein synthesis. Annu Rev Biochem (1976) 3.66
Mutants of vesicular stomatitis virus blocked at different stages in maturation of the viral glycoprotein. Cell (1980) 3.65
Translation of reovirus mRNA, poliovirus RNA and bacteriophage Qbeta RNA in cell-free extracts of mammalian cells. Methods Enzymol (1974) 3.60
Elevated levels of glucose transport and transporter messenger RNA are induced by ras or src oncogenes. Science (1987) 3.44
Beta-turns in proteins. J Mol Biol (1977) 3.43
Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin. Nat Immunol (2000) 3.42
Model for the regulation of mRNA translation applied to haemoglobin synthesis. Nature (1974) 3.37
Maturation of viral proteins in cells infected with temperature-sensitive mutants of vesicular stomatitis virus. J Virol (1977) 3.30
Expression cloning of SR-BI, a CD36-related class B scavenger receptor. J Biol Chem (1994) 3.29
Alpha and beta globin messenger ribonucleic acid. Different amounts and rates of initiation of translation. J Biol Chem (1971) 3.24
Developmental regulation of Dictyostelium discoideum actin gene fusions carried on low-copy and high-copy transformation vectors. Mol Cell Biol (1986) 3.20
Localization of two cellular forms of the vesicular stomatitis viral glycoprotein. J Virol (1977) 3.20
Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins. J Biol Chem (1997) 3.14
Translation of individual species of vesicular stomatitis viral mRNA. J Virol (1975) 3.12
Translation of vesicular stomatitis messenger RNA by extracts from mammalian and plant cells. J Virol (1974) 3.06
A glucose transport protein expressed predominately in insulin-responsive tissues. Proc Natl Acad Sci U S A (1989) 2.98
Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells. Proc Natl Acad Sci U S A (1997) 2.97
Molecular cloning of caveolin-3, a novel member of the caveolin gene family expressed predominantly in muscle. J Biol Chem (1996) 2.95
Biosynthesis of HLA-A and HLA-B antigens in vivo. J Biol Chem (1980) 2.94
Translation of murine leukemia virus RNA in cell-free systems from animal cells. J Virol (1976) 2.94
Expression cloning and characterization of the TGF-beta type III receptor. Cell (1991) 2.89
Secondary structure of bacteriophage f2 ribonucleic acid and the initiation of in vitro protein biosynthesis. J Mol Biol (1970) 2.89
Bacteriophage f2 RNA: control of translation and gene order. Nature (1968) 2.87
Translation in vitro of vesicular stomatitis virus mRNA lacking 5'-terminal 7-methylguanosine. Nature (1976) 2.81
The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains. Mol Cell Biol (1991) 2.77
An internal signal sequence: the asialoglycoprotein receptor membrane anchor. Cell (1986) 2.74
Prediction of beta-turns. Biophys J (1979) 2.71
Translation of reovirus messenger RNAs synthetesized in vitro into reovirus polypeptides by several mammalian cell-free extracts. Proc Natl Acad Sci U S A (1972) 2.69
Induction of caveolin during adipogenesis and association of GLUT4 with caveolin-rich vesicles. J Cell Biol (1994) 2.69
Identification, sequence, and expression of caveolin-2 defines a caveolin gene family. Proc Natl Acad Sci U S A (1996) 2.68
Identification of the major intestinal fatty acid transport protein. Mol Cell (1999) 2.65
Primary structure and transmembrane orientation of the murine anion exchange protein. Nature (1985) 2.61
Specificity in bacterial protein synthesis: role of initiation factors and ribosomal subunits. Nature (1970) 2.57
Developmental changes in messenger RNAs and protein synthesis in Dictyostelium discoideum. Dev Biol (1977) 2.55
The human glucose transporter can insert posttranslationally into microsomes. Cell (1986) 2.53
Analysis of the defects of temperature-sensitive mutants of vesicular stomatitis virus: intracellular degradation of specific viral proteins. J Virol (1977) 2.52
Replication of the RNA of Bacteriophage f2. Science (1966) 2.48
Synthesis and stability of developmentally regulated dictyostelium mRNAs are affected by cell--cell contact and cAMP. Cell (1981) 2.47
Regulation of dictyostelium discoideum mRNAs specific for prespore or prestalk cells. Cell (1983) 2.45
The sucrase-isomaltase complex: primary structure, membrane-orientation, and evolution of a stalked, intrinsic brush border protein. Cell (1986) 2.43
Kinetics of internalization and recycling of the asialoglycoprotein receptor in a hepatoma cell line. J Biol Chem (1982) 2.35
Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity. Nature (1990) 2.33
Circular dichroism and optical rotatory dispersion of proteins and polypeptides. Methods Enzymol (1973) 2.32
Homodimerization and constitutive activation of the erythropoietin receptor. Proc Natl Acad Sci U S A (1992) 2.29
Synergistic cooperation of TFE3 and smad proteins in TGF-beta-induced transcription of the plasminogen activator inhibitor-1 gene. Genes Dev (1998) 2.29
Caveolin isoforms differ in their N-terminal protein sequence and subcellular distribution. Identification and epitope mapping of an isoform-specific monoclonal antibody probe. J Biol Chem (1995) 2.25
Friend spleen focus-forming virus glycoprotein gp55 interacts with the erythropoietin receptor in the endoplasmic reticulum and affects receptor metabolism. Proc Natl Acad Sci U S A (1990) 2.23
Sequence of a second human asialoglycoprotein receptor: conservation of two receptor genes during evolution. Proc Natl Acad Sci U S A (1985) 2.22
TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation. Nat Cell Biol (2001) 2.22
How a single Sindbis virus mRNA directs the synthesis of one soluble protein and two integral membrane glycoproteins. Cell (1977) 2.19
A family of fatty acid transporters conserved from mycobacterium to man. Proc Natl Acad Sci U S A (1998) 2.12
Glycosylation of a membrane protein is restricted to the growing polypeptide chain but is not necessary for insertion as a transmembrane protein. Cell (1978) 2.11
The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor. Mol Cell (2001) 2.10
Activation of the erythropoietin receptor promoter by transcription factor GATA-1. Proc Natl Acad Sci U S A (1991) 2.10
The asialoglycoprotein receptor internalizes and recycles independently of the transferrin and insulin receptors. Cell (1983) 2.10
Analysis of the circular dichroism spectrum of proteins using the convex constraint algorithm: a practical guide. Anal Biochem (1992) 2.07
SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling. Proc Natl Acad Sci U S A (1999) 2.06
Localization of the pancreatic beta cell glucose transporter to specific plasma membrane domains. Science (1989) 2.04
Characterization of the asialoglycoprotein receptor in a continuous hepatoma line. J Biol Chem (1981) 2.04
A simple and inexpensive procedure for preparative polyacrylamide gel electrophoresis of RNA. Anal Biochem (1973) 2.04
Liver glucose transporter: a basolateral protein in hepatocytes and intestine and kidney cells. Am J Physiol (1990) 2.03
A small nuclear precursor of messenger RNA in the cellular slime mold Dictyostelium discoideum. J Mol Biol (1973) 2.01
Ligand-independent oligomerization of cell-surface erythropoietin receptor is mediated by the transmembrane domain. Proc Natl Acad Sci U S A (2001) 2.00
Glucose removal from N-linked oligosaccharides is required for efficient maturation of certain secretory glycoproteins from the rough endoplasmic reticulum to the Golgi complex. J Cell Biol (1984) 1.97
Vesicular stomatitis virus glycoprotein, albumin, and transferrin are transported to the cell surface via the same Golgi vesicles. J Cell Biol (1983) 1.94
Initiation sites for translation of sindbis virus 42S and 26S messenger RNAs. Cell (1975) 1.94
Single-stranded oligomers and polymers of cytidylic and 2'-deoxycytidylic acids: comparative optical rotatory studies. Proc Natl Acad Sci U S A (1967) 1.94
Cloning and functional expression of a vascular smooth muscle endothelin 1 receptor. Proc Natl Acad Sci U S A (1991) 1.93