Empirical predictions of protein conformation.

Profile analysis: detection of distantly related proteins. Proc Natl Acad Sci U S A (1987) 29.26

Mitochondrial targeting sequences may form amphiphilic helices. EMBO J (1986) 7.11

The hydrophobic moment detects periodicity in protein hydrophobicity. Proc Natl Acad Sci U S A (1984) 6.36

Mechanisms of protein localization. Microbiol Rev (1983) 6.12

GlobPlot: Exploring protein sequences for globularity and disorder. Nucleic Acids Res (2003) 5.90

Nucleotide sequence of an mRNA transcribed in latent growth-transforming virus infection indicates that it may encode a membrane protein. J Virol (1984) 5.87

Bacteriophage lysis: mechanism and regulation. Microbiol Rev (1992) 4.95

One of two Epstein-Barr virus nuclear antigens contains a glycine-alanine copolymer domain. Proc Natl Acad Sci U S A (1983) 4.94

Mapping of sequences required for mouse neurovirulence of poliovirus type 2 Lansing. J Virol (1986) 4.91

A yeast nucleolar protein related to mammalian fibrillarin is associated with small nucleolar RNA and is essential for viability. EMBO J (1989) 4.91

Major cold shock protein of Escherichia coli. Proc Natl Acad Sci U S A (1990) 4.90

Analysis of cloned cDNA and genomic sequences for phytochrome: complete amino acid sequences for two gene products expressed in etiolated Avena. Nucleic Acids Res (1985) 4.45

The protein folding problem. Annu Rev Biophys (2008) 4.43

The petunia chlorophyll a/b binding protein genes: a comparison of Cab genes from different gene families. Nucleic Acids Res (1985) 4.32

Biochemical characterization of a gamma interferon-inducible cytokine (IP-10). J Exp Med (1987) 4.21

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. Proc Natl Acad Sci U S A (1987) 4.19

A family of extracytoplasmic proteins that allow transport of large molecules across the outer membranes of gram-negative bacteria. J Bacteriol (1994) 4.14

The cytochrome oxidase subunit I and subunit III genes in Oenothera mitochondria are transcribed from identical promoter sequences. EMBO J (1987) 4.10

Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro. Proc Natl Acad Sci U S A (1987) 4.04

The structure of cell adhesion molecule uvomorulin. Insights into the molecular mechanism of Ca2+-dependent cell adhesion. EMBO J (1987) 4.00

All-D amino acid-containing channel-forming antibiotic peptides. Proc Natl Acad Sci U S A (1990) 4.00

A unique structure at the carboxyl terminus of the largest subunit of eukaryotic RNA polymerase II. Proc Natl Acad Sci U S A (1985) 3.98

A helix propensity scale based on experimental studies of peptides and proteins. Biophys J (1998) 3.95

Early auxin-induced genes encode short-lived nuclear proteins. Proc Natl Acad Sci U S A (1994) 3.93

Enhanced protein thermostability from site-directed mutations that decrease the entropy of unfolding. Proc Natl Acad Sci U S A (1987) 3.85

The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction. Proc Natl Acad Sci U S A (1992) 3.74

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease. Proc Natl Acad Sci U S A (1993) 3.73

A Myb-related transcription factor is involved in the phytochrome regulation of an Arabidopsis Lhcb gene. Plant Cell (1997) 3.54

Arabidopsis HY8 locus encodes phytochrome A. Plant Cell (1993) 3.52

NH2-terminal amino acid sequences of precursor and mature forms of the ribulose-1,5-bisphosphate carboxylase small subunit from Chlamydomonas reinhardtii. J Cell Biol (1979) 3.47

Amino acid sequences that determine the nuclear localization of yeast histone 2B. Mol Cell Biol (1987) 3.31

Functional analysis of the chromo domain of HP1. EMBO J (1995) 3.30

Identification of the human c-myc protein nuclear translocation signal. Mol Cell Biol (1988) 3.30

Mutations that alter an Arg-Gly-Asp (RGD) sequence in the adenovirus type 2 penton base protein abolish its cell-rounding activity and delay virus reproduction in flat cells. J Virol (1993) 3.29

Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation. Proc Natl Acad Sci U S A (1990) 3.29

Complete amino acid sequence of beta-tubulin from porcine brain. Proc Natl Acad Sci U S A (1981) 3.24

Simian virus 40 large T antigen is phosphorylated at multiple sites clustered in two separate regions. J Virol (1982) 3.18

cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1. EMBO J (1989) 3.10

Functional determinants in transit sequences: import and partial maturation by vascular plant chloroplasts of the ribulose-1,5-bisphosphate carboxylase small subunit of Chlamydomonas. J Cell Biol (1985) 3.01

Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivo. J Virol (1993) 2.94

Transit peptides of nuclear-encoded chloroplast proteins share a common amino acid framework. EMBO J (1986) 2.89

B lymphocyte lineage-restricted expression of mb-1, a gene with CD3-like structural properties. EMBO J (1988) 2.88

A Bacteroides thetaiotaomicron outer membrane protein that is essential for utilization of maltooligosaccharides and starch. J Bacteriol (1996) 2.87

Viral and cellular fos proteins are complexed with a 39,000-dalton cellular protein. Mol Cell Biol (1985) 2.86

The bcl-2 candidate proto-oncogene product is a 24-kilodalton integral-membrane protein highly expressed in lymphoid cell lines and lymphomas carrying the t(14;18) translocation. Mol Cell Biol (1989) 2.84

Fusion protein of the paramyxovirus simian virus 5: nucleotide sequence of mRNA predicts a highly hydrophobic glycoprotein. Proc Natl Acad Sci U S A (1984) 2.82

Complete amino acid sequence of alpha-tubulin from porcine brain. Proc Natl Acad Sci U S A (1981) 2.82

Extensive homology between the leukotoxin of Pasteurella haemolytica A1 and the alpha-hemolysin of Escherichia coli. Infect Immun (1987) 2.78

Sequence and tissue distribution of a second protein of hepatic gap junctions, Cx26, as deduced from its cDNA. J Cell Biol (1989) 2.74

Primary sequence analysis of Clostridium cellulovorans cellulose binding protein A. Proc Natl Acad Sci U S A (1992) 2.73

Strain-specific and common epitopes of gonococcal pili. J Exp Med (1984) 2.72

Characterization of four outer membrane proteins that play a role in utilization of starch by Bacteroides thetaiotaomicron. J Bacteriol (1997) 2.72

Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions. Cell (2011) 2.68

Human Mig chemokine: biochemical and functional characterization. J Exp Med (1995) 2.67

Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase. Mol Cell Biol (1995) 2.66

Mutant influenza viruses with a defective NS1 protein cannot block the activation of PKR in infected cells. J Virol (1999) 2.65

Neurofilament architecture combines structural principles of intermediate filaments with carboxy-terminal extensions increasing in size between triplet proteins. EMBO J (1983) 2.64

Periodicity of leucine and tandem repetition of a 24-amino acid segment in the primary structure of leucine-rich alpha 2-glycoprotein of human serum. Proc Natl Acad Sci U S A (1985) 2.64

A structural model of the tetrodotoxin and saxitoxin binding site of the Na+ channel. Biophys J (1994) 2.64

The yeast RAD50 gene encodes a predicted 153-kD protein containing a purine nucleotide-binding domain and two large heptad-repeat regions. Genetics (1989) 2.63

Primary sequence of the alpha-toxin gene from Staphylococcus aureus wood 46. Infect Immun (1984) 2.60

Nucleotide sequence of the gene for the vitamin B12 receptor protein in the outer membrane of Escherichia coli. J Bacteriol (1985) 2.59

Yeast carboxypeptidase Y vacuolar targeting signal is defined by four propeptide amino acids. J Cell Biol (1990) 2.57

Signal transduction and transcriptional and posttranscriptional control of iron-regulated genes in bacteria. Microbiol Mol Biol Rev (1997) 2.56

Proaleurain vacuolar targeting is mediated by short contiguous peptide interactions. Plant Cell (1992) 2.55

Molecular cloning and sequence analysis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene. Proc Natl Acad Sci U S A (1987) 2.54

Synthetic lethality with fibrillarin identifies NOP77p, a nucleolar protein required for pre-rRNA processing and modification. EMBO J (1994) 2.53

Human alpha-galactosidase A: nucleotide sequence of a cDNA clone encoding the mature enzyme. Proc Natl Acad Sci U S A (1986) 2.51

Primary structures of human alpha-fetoprotein and its mRNA. Proc Natl Acad Sci U S A (1983) 2.49

A novel nucleoskeletal-like protein located at the nuclear periphery is required for the life cycle of Saccharomyces cerevisiae. EMBO J (1988) 2.42

Domain structure of the Acetogenium kivui surface layer revealed by electron crystallography and sequence analysis. J Bacteriol (1994) 2.40

Human cDNA clones for four species of G alpha s signal transduction protein. Proc Natl Acad Sci U S A (1986) 2.38

Mutations defining functional regions of the superantigen staphylococcal enterotoxin B. J Exp Med (1992) 2.38

Vaccinia virus 19-kilodalton protein: relationship to several mammalian proteins, including two growth factors. Proc Natl Acad Sci U S A (1984) 2.34

Folding patterns of porin and bacteriorhodopsin. EMBO J (1985) 2.34

Localization of allodeterminants on H-2Kb antigens determined with monoclonal antibodies and H-2 mutant mice. Proc Natl Acad Sci U S A (1982) 2.33

A GTP-binding protein of Escherichia coli has homology to yeast RAS proteins. Proc Natl Acad Sci U S A (1986) 2.32

Periodicity of polar and nonpolar amino acids is the major determinant of secondary structure in self-assembling oligomeric peptides. Proc Natl Acad Sci U S A (1995) 2.32

Covalent structure of biodegradative threonine dehydratase of Escherichia coli: homology with other dehydratases. Proc Natl Acad Sci U S A (1987) 2.31

A carboxy-terminal fragment of protein mu 1/mu 1C is present in infectious subvirion particles of mammalian reoviruses and is proposed to have a role in penetration. J Virol (1992) 2.29

Secondary structures of proteins and peptides in amphiphilic environments. (A review). Proc Natl Acad Sci U S A (1983) 2.26

Primary structure of the T3 gamma subunit of the T3/T cell antigen receptor complex deduced from cDNA sequences: evolution of the T3 gamma and delta subunits. EMBO J (1986) 2.25

Homology of the human intestinal Na+/glucose and Escherichia coli Na+/proline cotransporters. Proc Natl Acad Sci U S A (1989) 2.25

Human delta-aminolevulinate dehydratase: nucleotide sequence of a full-length cDNA clone. Proc Natl Acad Sci U S A (1986) 2.25

Identification, transmembrane orientation and biogenesis of the amyloid A4 precursor of Alzheimer's disease. EMBO J (1988) 2.23

Structural analysis of Alzheimer's beta(1-40) amyloid: protofilament assembly of tubular fibrils. Biophys J (1998) 2.22

Diversity and structure of human T-cell receptor beta-chain variable region genes. Proc Natl Acad Sci U S A (1986) 2.19

Evidence from molecular cloning that SPARC, a major product of mouse embryo parietal endoderm, is related to an endothelial cell 'culture shock' glycoprotein of Mr 43,000. EMBO J (1986) 2.18

Genetics and sequence analysis of the pcnB locus, an Escherichia coli gene involved in plasmid copy number control. J Bacteriol (1989) 2.18

Nucleotide sequences of the fecBCDE genes and locations of the proteins suggest a periplasmic-binding-protein-dependent transport mechanism for iron(III) dicitrate in Escherichia coli. J Bacteriol (1989) 2.17

Molecular cloning, characterization, and expression of a cDNA encoding the "80- to 87-kDa" myristoylated alanine-rich C kinase substrate: a major cellular substrate for protein kinase C. Proc Natl Acad Sci U S A (1989) 2.16

Sequence variation in the thermostable direct hemolysin-related hemolysin (trh) gene of Vibrio parahaemolyticus. Appl Environ Microbiol (1992) 2.16

DNA sequence of the Escherichia coli tonB gene. Proc Natl Acad Sci U S A (1983) 2.15

The prolamin storage proteins of cereal seeds: structure and evolution. Biochem J (1990) 2.13

Molecular cloning and amino acid sequence of human plakoglobin, the common junctional plaque protein. Proc Natl Acad Sci U S A (1989) 2.12

Sequence of the nifD gene coding for the alpha subunit of dinitrogenase from the cyanobacterium Anabaena. Proc Natl Acad Sci U S A (1983) 2.09

GTPase of bovine rod outer segments: the amino acid sequence of the alpha subunit as derived from the cDNA sequence. Proc Natl Acad Sci U S A (1985) 2.09

Mutagenic analysis of human immunodeficiency virus type 1 Vpr: role of a predicted N-terminal alpha-helical structure in Vpr nuclear localization and virion incorporation. J Virol (1995) 2.09

Enteropathogenic Escherichia coli: identification of a gene cluster coding for bundle-forming pilus morphogenesis. J Bacteriol (1996) 2.08

Cloning and nucleotide sequence of the gene (trh) encoding the hemolysin related to the thermostable direct hemolysin of Vibrio parahaemolyticus. Infect Immun (1989) 2.07

Prediction of the secondary structure of proteins from their amino acid sequence. Adv Enzymol Relat Areas Mol Biol (1978) 29.77

Prediction of protein conformation. Biochemistry (1974) 20.51

Conformational parameters for amino acids in helical, beta-sheet, and random coil regions calculated from proteins. Biochemistry (1974) 12.07

Computed circular dichroism spectra for the evaluation of protein conformation. Biochemistry (1969) 10.58

Beta-turns in proteins. J Mol Biol (1977) 3.43

Prediction of beta-turns. Biophys J (1979) 2.71

Circular dichroism and optical rotatory dispersion of proteins and polypeptides. Methods Enzymol (1973) 2.32

Erythropoietin receptor and interleukin-2 receptor beta chain: a new receptor family. Cell (1989) 2.13

Analysis of the circular dichroism spectrum of proteins using the convex constraint algorithm: a practical guide. Anal Biochem (1992) 2.07

Single-stranded oligomers and polymers of cytidylic and 2'-deoxycytidylic acids: comparative optical rotatory studies. Proc Natl Acad Sci U S A (1967) 1.94

Convex constraint analysis: a natural deconvolution of circular dichroism curves of proteins. Protein Eng (1991) 1.83

Fluorescence studies on heavy meromyosin-substrate interaction. Biochemistry (1972) 1.68

Prediction of the conformation of the histones. Biophys J (1976) 1.54

The circular dichroism of the beta structure of poly-L-lysine. Biochem Biophys Res Commun (1966) 1.48

Circular dichroism of cytosine dinucleoside monophosphates containing arabinose, ribose, and deoxyribose. Biochemistry (1968) 1.46

Occurrence of phosphorylated residues in predicted beta-turns: implications for beta-turn participation in control mechanisms. Biochem Biophys Res Commun (1977) 1.38

Conformational studies of the synthetic precursor-specific region of preproparathyroid hormone. Proc Natl Acad Sci U S A (1980) 1.38

Conformational prediction and circular dichroism studies on the lac repressor. J Mol Biol (1975) 1.36

Conformational changes associated with f-1 histone-deoxyribonucleic acid complexes. Circular dichroism studies. Biochemistry (1970) 1.29

Fluorescence of lysozyme and lysozyme substrate complexes. Separation of tryptophan contributions by fluorescence difference methods. J Biol Chem (1967) 1.26

Circular dichroism of polypeptide and protein conformations. Film studies. Biochemistry (1970) 1.25

The conformation of glucagon: predictions and consequences. Biochemistry (1975) 1.24

Conformation of deoxyribonucleic acid in chromatin: a circular dichroism study. J Mol Biol (1970) 1.21

Comparison of predicted and experimentally determined secondary structure of adenyl kinase. Nature (1974) 1.21

Structural and functional role of leucine residues in proteins. J Mol Biol (1973) 1.21

Conformational dependence of fluorescence polarization spectra of L-tryptophan containing copolypeptides. Biopolymers (1968) 1.20

The T cell response to the glycoprotein D of the herpes simplex virus: the significance of antigen conformation. J Immunol (1985) 1.19

Ultraviolet irradiation effects in poly-L-tyrosine and model compounds. Identification of bityrosine as a photoproduct. Biochemistry (1967) 1.16

Chromatin and nucleosome structure. Nucleic Acids Res (1976) 1.15

The fluorescence of lysozyme and lysozyme substrate complexes. Biochem Biophys Res Commun (1966) 1.13

Differentiation between transmembrane helices and peripheral helices by the deconvolution of circular dichroism spectra of membrane proteins. Protein Sci (1992) 1.13

Polyriboadenylic and polydeoxyriboadenylic acids. Optical rotatory studies of pH-dependent conformations and their relative stability. Biochemistry (1969) 1.13

Optical rotatory dispersion studies on the conformational stabilization forces of yeast soluble ribonucleic acid. J Mol Biol (1965) 1.10

Calorimetric measurement of enthalpy change in the isothermal helix--coil transition of poly-L-lysine in aqueous solution. Biopolymers (1971) 1.10

Circular dichroism of polypeptides. Poly(hydroxyethyl-L-glutamine) compared to poly(L-glutamic acid). J Am Chem Soc (1968) 1.09

Conformational studies on copolymers of hydroxypropyl-L-glutamine and L-leucine. Circular dichroism studies. Biochemistry (1972) 1.09

The conformational transitions of uncharged poly-L-lysine. Alpha helix-random coil-beta structure. Biochemistry (1967) 1.09

The use of computed optical rotatory dispersion curves for the evaluation of protein conformation. Biochemistry (1967) 1.05

Quantitative analysis of cyclic beta-turn models. Protein Sci (1992) 1.03

Electron microscopy and circular dichroism studies on chromatin. Biochemistry (1972) 1.03

Deconvolution of the circular dichroism spectra of proteins: the circular dichroism spectra of the antiparallel beta-sheet in proteins. Proteins (1992) 1.00

The road from poly(alpha-amino acids) to the prediction of protein conformation. Biopolymers (1987) 0.99

Interaction of deoxyribonucleic acid with histone f2b and its half-molecules. Circular dichroism studies. Biochemistry (1974) 0.98

The circular dichroism of polypeptide films. Biochemistry (1968) 0.98

Study of conformational states and reversibility of histone complexes. Biochemistry (1981) 0.97

Analysis of chromatin reconstitutiion. Biochemistry (1979) 0.97

Conformation of the high pH form of chymotrypsin. J Mol Biol (1969) 0.96

CD and Fourier transform ir spectroscopic studies of peptides. II. Detection of beta-turns in linear peptides. Biopolymers (1994) 0.95

Conformational change of chaperone Hsc70 upon binding to a decapeptide: a circular dichroism study. Protein Sci (1993) 0.95

Circular dichroism studies of deoxyribonucleic acid complexes with arginine-rich histone IV (f2al). Biochemistry (1971) 0.95

Circular dichroism of valine and formylmethionine transfer RNA from Escherichia coli: effect of aminoacylation. Biochim Biophys Acta (1970) 0.95

Protein conformational prediction. Trends Biochem Sci (1989) 0.94

Circular dichroism analysis of mononucleosome DNA conformation. Proc Natl Acad Sci U S A (1978) 0.94

The structure of chromatin reconstituted with phosphorylated H1. Circular dichroism and thermal denaturation studies. J Biol Chem (1984) 0.93

The optical rotatory dispersion of the beta structure of poly-L-lysine and poly-L-serine. Biochem Biophys Res Commun (1966) 0.93

The evaluation of type I and type II beta-turn mixtures. Circular dichroism, NMR and molecular dynamics studies. Int J Pept Protein Res (1993) 0.92

The optical rotatory dispersion of two beta structures. Biochem Biophys Res Commun (1967) 0.92

Metal ion-induced conformational changes of phosphorylated fragments of human neurofilament (NF-M) protein. J Mol Biol (1992) 0.92

Peptide models for beta-turns. A circular dichroism study. Int J Pept Protein Res (1984) 0.92

The conformational transition associated with the activation of chymotrypsinogen to chymotrypsin. J Mol Biol (1966) 0.91

Altered conformational effects of phosphorylated lysine-rich histone (f-1) in f-1--deoxyribonucleic acid complexes. Circular dichroism and immunological studies. Biochemistry (1971) 0.91

Conservation of chain reversal regions in proteins. Biophys J (1979) 0.90

Ionic strength-dependent conformational transitions of chromatin. Circular dichroism and thermal denaturation studies. Biopolymers (1979) 0.90

A new hematopoietic growth factor receptor superfamily: structural features and implications for signal transduction. Curr Opin Cell Biol (1990) 0.89

Sodium butyrate induced structural changes in HeLa cell chromatin. Biochemistry (1982) 0.89

Circular dichroism studies of histone-deoxyribonucleic acid complexes. A comparison of complexes with histone I (f-1), histone IV (f2al), and their mixtures. Biochemistry (1972) 0.89

Structural studies of acetylated and control inner core histones. Biochemistry (1987) 0.88

Characterization of beta-turns in cyclic hexapeptides in solution by Fourier transform IR spectroscopy. Biopolymers (1993) 0.87

Kinetics and thermodynamics of the helix leads to transconformation of poly(L-lysine) and L-leucine copolymers. A compensation phenomenon. Biochemistry (1973) 0.87

The single-stranded polyadenylic acid-poly-L-lysine complex. A conformational study and characterization. Biochemistry (1969) 0.85

Ca(2+)-induced conformational transitions of phosphorylated peptides. Biopolymers (1993) 0.85

Dependence of mononucleosome deoxyribonucleic acid conformation on the deoxyribonucleic acid length and H1/H5 content. Circular dichroism and thermal denaturation studies. Biochemistry (1980) 0.85

Conformational studies on poly-L-glutamic acid and copolymers of L-glutamic acid and L-phenylalanine. Biochemistry (1966) 0.85

A poly(ethylene glycol) water-soluble conjugate of porin: refolding to the native state. Biochemistry (1995) 0.85

Complexes of deoxyribonucleic acid with fragments of lysine-rich histone (f-1). Circular dichroism studies. Biochemistry (1971) 0.84

Complexes of deoxyribonucleic acid with lysine-rich (f1) histone phosphorylated at two separate sites: circular dichroism studies. Arch Biochem Biophys (1972) 0.83

A conformational study of the binding of a high mobility group protein with chromatin. J Biol Chem (1982) 0.83

Melting of the left-handed helical conformation of charged poly-L-lysine. Biopolymers (1994) 0.83

Intrinsic tryptophan fluorescence of membranes of GH3 pituitary cells: quenching by thyrotropin-releasing hormone. Biochem Biophys Res Commun (1975) 0.83

Thermal denaturation of DNA and DNA:polypeptide complexes. Simultaneous absorption and circular dichroism measurements. Biochem Biophys Res Commun (1974) 0.83

The beta conformation of polypeptides of valine, isoleucine, and threonine in solution and solid-state: optical and infrared studies. Biopolymers (1975) 0.82

How reverse turns may mediate the formation of helical segments in proteins: an x-ray model. Proc Natl Acad Sci U S A (1992) 0.82

Hydrogen-tritium exchange in polypeptides. Models of alpha-helical and beta conformations. Biochemistry (1974) 0.82

Altered conformational effects of naturally acetylated histone f2al (IV) in f2al-deoxyribonucleic acid complexes. Circular dichroism studies. J Biol Chem (1974) 0.81

The effect of a high mobility group protein (HMG 17) on the structure of acetylated and control core HeLa cell chromatin. Biochim Biophys Acta (1984) 0.81

Interaction of histone f2al fragments with deoxyribonucleic acid. Circular dichroism and thermal denaturation studies. Biochemistry (1975) 0.81

Beta-turns in bridged proline-containing cyclic peptide models. Biopolymers (1987) 0.81