Published in Cell Mol Life Sci on December 24, 2014
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Inactivation of the autophagy gene bec-1 triggers apoptotic cell death in C. elegans. Curr Biol (2005) 2.86
Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans. Autophagy (2008) 2.83
European best practice guidelines for cystic fibrosis neonatal screening. J Cyst Fibros (2009) 1.75
Cystic fibrosis diagnosed after 2 months of age leads to worse outcomes and requires more therapy. Pediatrics (2007) 1.73
Economic implications of newborn screening for cystic fibrosis: a cost of illness retrospective cohort study. Lancet (2007) 1.66
Decreased lung function in female but not male subjects with established cystic fibrosis-related diabetes. Diabetes Care (2005) 1.56
Sequestration revisited: integrating traditional electron microscopy, de novo assembly and new results. Autophagy (2007) 1.55
Demographics of the UK cystic fibrosis population: implications for neonatal screening. Eur J Hum Genet (2002) 1.33
SignaLink 2 - a signaling pathway resource with multi-layered regulatory networks. BMC Syst Biol (2013) 1.30
Uniformly curated signaling pathways reveal tissue-specific cross-talks and support drug target discovery. Bioinformatics (2010) 1.27
Comparative demographics of the European cystic fibrosis population: a cross-sectional database analysis. Lancet (2010) 1.22
Mechanistic insight into control of CFTR by AMPK. J Biol Chem (2008) 1.21
Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation. Autophagy (2014) 1.21
Liquid secretion inhibitors reduce mucociliary transport in glandular airways. Am J Physiol Lung Cell Mol Physiol (2002) 1.10
Expression of wild-type CFTR suppresses NF-kappaB-driven inflammatory signalling. PLoS One (2010) 1.08
Influence of autophagy genes on ion-channel-dependent neuronal degeneration in Caenorhabditis elegans. J Cell Sci (2007) 1.07
Transcriptional control of Notch signaling by a HOX and a PBX/EXD protein during vulval development in C. elegans. Dev Biol (2006) 1.06
Comparative analysis of Cystic Fibrosis Registry data from the UK with USA, France and Australasia. J Cyst Fibros (2005) 1.05
Network-based tools for the identification of novel drug targets. Sci Signal (2011) 1.03
Autophagy genes unc-51 and bec-1 are required for normal cell size in Caenorhabditis elegans. Genetics (2007) 1.01
A novel actin binding site of myosin required for effective muscle contraction. Nat Struct Mol Biol (2012) 1.00
Clinical and sociodemographic study of vitiligo. Indian J Dermatol Venereol Leprol (2009) 0.99
Qualitative and quantitative characterization of autophagy in Caenorhabditis elegans by electron microscopy. Methods Enzymol (2008) 0.99
Novel regulation of cystic fibrosis transmembrane conductance regulator (CFTR) channel gating by external chloride. J Biol Chem (2004) 0.99
Speciation in Chlamydia: genomewide phylogenetic analyses identified a reliable set of acquired genes. J Mol Evol (2003) 0.98
Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect functional links with cystic fibrosis pathogenesis. Biochemistry (2008) 0.98
Cystic fibrosis across Europe: EuroCareCF analysis of demographic data from 35 countries. J Cyst Fibros (2010) 0.98
Shared developmental roles and transcriptional control of autophagy and apoptosis in Caenorhabditis elegans. J Cell Sci (2011) 0.96
CFTR: a hub for kinases and crosstalk of cAMP and Ca2+. FEBS J (2013) 0.95
Regulation of the epithelial Na+ channel by the protein kinase CK2. J Biol Chem (2008) 0.95
The formation of the cAMP/protein kinase A-dependent annexin 2-S100A10 complex with cystic fibrosis conductance regulator protein (CFTR) regulates CFTR channel function. Mol Biol Cell (2007) 0.95
Newborn screening for cystic fibrosis is associated with reduced treatment intensity. J Pediatr (2005) 0.95
Inhibition of protein kinase CK2 closes the CFTR Cl channel, but has no effect on the cystic fibrosis mutant deltaF508-CFTR. Cell Physiol Biochem (2009) 0.94
Complex regulation of autophagy in cancer - integrated approaches to discover the networks that hold a double-edged sword. Semin Cancer Biol (2013) 0.92
Making human nasal cilia beat in the cold: a real time assay for cell signalling. Cell Signal (2003) 0.92
The phosphorylation status of membrane-bound nucleoside diphosphate kinase in epithelia and the role of AMP. Mol Cell Biochem (2009) 0.91
The European Cystic Fibrosis Society Patient Registry: valuable lessons learned on how to sustain a disease registry. Orphanet J Rare Dis (2014) 0.90
Nucleoside diphosphate kinase A as a controller of AMP-kinase in airway epithelia. J Bioenerg Biomembr (2006) 0.90
xol-1, the master sex-switch gene in C. elegans, is a transcriptional target of the terminal sex-determining factor TRA-1. Development (2009) 0.89
TRA-1/GLI controls the expression of the Hox gene lin-39 during C. elegans vulval development. Dev Biol (2009) 0.88
Ancestral haplotype 8.1 and lung disease severity in European cystic fibrosis patients. J Cyst Fibros (2011) 0.88
Contribution of casein kinase 2 and spleen tyrosine kinase to CFTR trafficking and protein kinase A-induced activity. Mol Cell Biol (2011) 0.87
Base excision repair AP endonucleases and mismatch repair act together to induce checkpoint-mediated autophagy. Nat Commun (2013) 0.87
Autophagy in neuronal cell loss: a road to death. Bioessays (2006) 0.87
Retracted Protein kinase CK2, cystic fibrosis transmembrane conductance regulator, and the deltaF508 mutation: F508 deletion disrupts a kinase-binding site. J Biol Chem (2007) 0.87
CFTR gene transfer to human cystic fibrosis pancreatic duct cells using a Sendai virus vector. J Cell Physiol (2008) 0.87
Retracted A novel physical and functional association between nucleoside diphosphate kinase A and AMP-activated protein kinase alpha1 in liver and lung. Biochem J (2005) 0.87
Distribution and evolution of short tandem repeats in closely related bacterial genomes. Gene (2007) 0.86
Neonatal screening for cystic fibrosis is beneficial even in the context of modern treatment. J Pediatr (2005) 0.86
Delayed diagnosis of females with respiratory presentation of cystic fibrosis did not segregate with poorer clinical outcome. J Clin Epidemiol (2006) 0.85
Signalogs: orthology-based identification of novel signaling pathway components in three metazoans. PLoS One (2011) 0.85
Asians with cystic fibrosis in the UK have worse disease outcomes than clinic matched white homozygous delta F508 controls. J Cyst Fibros (2005) 0.85
Acute bacterial rhinosinusitis and its complications in our pediatric otolaryngological department between 1997 and 2006. Int J Pediatr Otorhinolaryngol (2009) 0.85
Detection of phospho-sites generated by protein kinase CK2 in CFTR: mechanistic aspects of Thr1471 phosphorylation. PLoS One (2013) 0.85
Dictyostelium discoideum nucleoside diphosphate kinase C plays a negative regulatory role in phagocytosis, macropinocytosis and exocytosis. PLoS One (2011) 0.84
Stomatin immunoreactivity in ciliated cells of the human airway epithelium. Anat Embryol (Berl) (2003) 0.84
The maintenance of sex in bacteria is ensured by its potential to reload genes. Genetics (2006) 0.84
Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2. Biochem J (2010) 0.84
Autophagy in Caenorhabditis elegans. Methods Enzymol (2008) 0.84
Retracted Understanding the molecular basis of the interaction between NDPK-A and AMPK alpha 1. Mol Cell Biol (2006) 0.84
NDPK-A (but not NDPK-B) and AMPK alpha1 (but not AMPK alpha2) bind the cystic fibrosis transmembrane conductance regulator in epithelial cell membranes. Cell Signal (2006) 0.83
Reference percentiles for FEV(1) and BMI in European children and adults with cystic fibrosis. Orphanet J Rare Dis (2012) 0.83
Overweight and obesity in deltaF508 homozygous cystic fibrosis. J Pediatr (2005) 0.82
The C. elegans Hox gene ceh-13 regulates cell migration and fusion in a non-colinear way. Implications for the early evolution of Hox clusters. BMC Dev Biol (2010) 0.82
Differential expression of purinergic receptor subtypes in the outer hair cells of the guinea pig. Hear Res (2004) 0.82
Autophagy Regulatory Network - a systems-level bioinformatics resource for studying the mechanism and regulation of autophagy. Autophagy (2015) 0.81
Identifying novel genes involved in both deer physiological and human pathological osteoporosis. Mol Genet Genomics (2008) 0.81
4alpha-Phorbol negates the inhibitory effects of phorbol-12-myristate-13-acetate on human cilia and alters the phosphorylation of PKC. FEBS Lett (2002) 0.81
Small interfering peptide (siP) for in vivo examination of the developing lung interactonome. Dev Dyn (2009) 0.81
Role of binding and nucleoside diphosphate kinase A in the regulation of the cystic fibrosis transmembrane conductance regulator by AMP-activated protein kinase. J Biol Chem (2012) 0.81
Heat shock factor-1 intertwines insulin/IGF-1, TGF-β and cGMP signaling to control development and aging. BMC Dev Biol (2012) 0.81
Origins of chemical evolution. Acc Chem Res (2012) 0.81
A methodology to establish a database to study gene environment interactions for childhood asthma. BMC Med Res Methodol (2010) 0.81
Autophagy and apoptosis are redundantly required for C. elegans embryogenesis. Autophagy (2011) 0.80
The NM23-H1/H2 homolog NDK-1 is required for full activation of Ras signaling in C. elegans. Development (2013) 0.80
CFTR mutations altering CFTR fragmentation. Biochem J (2013) 0.80
The mechanism of ageing: primary role of transposable elements in genome disintegration. Cell Mol Life Sci (2015) 0.80
Epithelial IgG and its relationship to the loss of F508 in the common mutant form of the cystic fibrosis transmembrane conductance regulator. FEBS Lett (2009) 0.79
A genetic interaction between NDPK and AMPK in Dictyostelium discoideum that affects motility, growth and development. Naunyn Schmiedebergs Arch Pharmacol (2011) 0.79
Understanding protein kinase CK2 mis-regulation upon F508del CFTR expression. Naunyn Schmiedebergs Arch Pharmacol (2011) 0.79
Transglutaminase 2 and nucleoside diphosphate kinase activity are correlated in epithelial membranes and are abnormal in cystic fibrosis. FEBS Lett (2009) 0.78
Retracted Protein kinase CK2 acts as a signal molecule switching between the NDPK-A/AMPK alpha1 complex and NDPK-B. FASEB J (2006) 0.77
Defective formation of PKA/CnA-dependent annexin 2-S100A10/CFTR complex in DeltaF508 cystic fibrosis cells. Cell Signal (2008) 0.77
Fertility and pregnancy outcomes in men and women with cystic fibrosis in the United Kingdom. Hum Reprod (2004) 0.77
Metformin treatment of diabetes mellitus increases the risk for pancreatitis in patients bearing the CFTR-mutation S573C. Cell Physiol Biochem (2010) 0.77
Protein kinase CK2 acts as a signal molecule switching between the NDPK-A/AMPK 1 complex and NDPK-B. FASEB J (2007) 0.76
The Caenorhabditis elegans ortholog of C21orf80, a potential new protein O-fucosyltransferase, is required for normal development. Genomics (2004) 0.75
Uniform curation protocol of metazoan signaling pathways to predict novel signaling components. Methods Mol Biol (2013) 0.75
Teaching the bioinformatics of signaling networks: an integrated approach to facilitate multi-disciplinary learning. Brief Bioinform (2013) 0.75
Protein kinase CK2, cystic fibrosis transmembrane conductance regulator, and the deltaF508 mutation: F508 deletion disrupts a kinase-binding site. J Biol Chem (2008) 0.75
History and development of pediatric otorhinolaryngology in Hungary. Int J Pediatr Otorhinolaryngol (2009) 0.75
Identification of novel cis-regulatory regions from the Notch receptor genes lin-12 and glp-1 of Caenorhabditis elegans. Gene Expr Patterns (2013) 0.75