Published in FEBS Lett on July 09, 2009
Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2. Biochem J (2010) 0.84
CFTR mutations altering CFTR fragmentation. Biochem J (2013) 0.80
Understanding protein kinase CK2 mis-regulation upon F508del CFTR expression. Naunyn Schmiedebergs Arch Pharmacol (2011) 0.79
The unlabeled antibody enzyme method of immunohistochemistry: preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes. J Histochem Cytochem (1970) 20.22
Impact of the deltaF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure. J Biol Chem (2004) 2.66
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Innate immune response in CF airway epithelia: hyperinflammatory? Am J Physiol Cell Physiol (2006) 1.69
Early alterations in airway mucociliary clearance and inflammation of the lamina propria in CF mice. Am J Physiol (1997) 1.54
Evaluating plague and smallpox as historical selective pressures for the CCR5-Delta 32 HIV-resistance allele. Proc Natl Acad Sci U S A (2003) 1.49
Differential localization of the cystic fibrosis transmembrane conductance regulator in normal and cystic fibrosis airway epithelium. Am J Respir Cell Mol Biol (1992) 1.33
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cAMP-dependent protein kinase-mediated phosphorylation of cystic fibrosis transmembrane conductance regulator residue Ser-753 and its role in channel activation. J Biol Chem (1995) 1.22
Structure of peptostreptococcal protein L and identification of a repeated immunoglobulin light chain-binding domain. J Biol Chem (1992) 1.11
Genetic analysis of the vaccinia virus I6 telomere-binding protein uncovers a key role in genome encapsidation. J Virol (2003) 1.10
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A novel chloride-dependent GTP-utilizing protein kinase in plasma membranes from human respiratory epithelium. Am J Physiol (1994) 1.01
Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect functional links with cystic fibrosis pathogenesis. Biochemistry (2008) 0.98
Comparison of methods for immobilization to carboxymethyl dextran sensor surfaces by analysis of the specific activity of monoclonal antibodies. J Mol Recognit (1995) 0.95
Relationship between IkappaBalpha deficiency, NFkappaB activity and interleukin-8 production in CF human airway epithelial cells. Pflugers Arch (2001) 0.93
Nucleoside diphosphate kinase and Cl(-)-sensitive protein phosphorylation in apical membranes from ovine airway epithelium. Am J Respir Cell Mol Biol (1998) 0.92
Normalization of ion transport in murine cystic fibrosis nasal epithelium using gene transfer. Am J Physiol (1997) 0.92
Can a place of origin of the main cystic fibrosis mutations be identified? Am J Hum Genet (2001) 0.90
Small interfering peptide (siP) for in vivo examination of the developing lung interactonome. Dev Dyn (2009) 0.81
The GPR54 gene as a regulator of puberty. N Engl J Med (2003) 9.54
Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54. Proc Natl Acad Sci U S A (2005) 3.79
Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a. Proc Natl Acad Sci U S A (2002) 3.59
Transcriptional pathway signatures predict MEK addiction and response to selumetinib (AZD6244). Cancer Res (2010) 3.54
Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene. Proc Natl Acad Sci U S A (2007) 2.66
Synthetic chemerin-derived peptides suppress inflammation through ChemR23. J Exp Med (2008) 2.54
Kisspeptin-GPR54 signaling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge. J Neurosci (2008) 2.38
Stella is a maternal effect gene required for normal early development in mice. Curr Biol (2003) 2.38
Aminoglycoside suppression of a premature stop mutation in a Cftr-/- mouse carrying a human CFTR-G542X transgene. J Mol Med (Berl) (2002) 2.34
Regional copy number-independent deregulation of transcription in cancer. Nat Genet (2006) 2.33
The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform. Diabetes (2005) 1.76
European best practice guidelines for cystic fibrosis neonatal screening. J Cyst Fibros (2009) 1.75
Impaired impulse propagation in Scn5a-knockout mice: combined contribution of excitability, connexin expression, and tissue architecture in relation to aging. Circulation (2005) 1.74
Cystic fibrosis diagnosed after 2 months of age leads to worse outcomes and requires more therapy. Pediatrics (2007) 1.73
Mouse model of SCN5A-linked hereditary Lenègre's disease: age-related conduction slowing and myocardial fibrosis. Circulation (2005) 1.69
Kisspeptin can stimulate gonadotropin-releasing hormone (GnRH) release by a direct action at GnRH nerve terminals. Endocrinology (2008) 1.66
Economic implications of newborn screening for cystic fibrosis: a cost of illness retrospective cohort study. Lancet (2007) 1.66
Mouse models of cystic fibrosis: phenotypic analysis and research applications. J Cyst Fibros (2011) 1.61
Decreased lung function in female but not male subjects with established cystic fibrosis-related diabetes. Diabetes Care (2005) 1.56
Innate BALB/c enteric epithelial responses to Trichinella spiralis: inducible expression of a novel goblet cell lectin, intelectin-2, and its natural deletion in C57BL/10 mice. J Immunol (2004) 1.47
The cyclin A1-CDK2 complex regulates DNA double-strand break repair. Mol Cell Biol (2004) 1.43
Distribution and postnatal development of Gpr54 gene expression in mouse brain and gonadotropin-releasing hormone neurons. Endocrinology (2009) 1.40
Demographics of the UK cystic fibrosis population: implications for neonatal screening. Eur J Hum Genet (2002) 1.33
Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a. J Physiol (2005) 1.27
Variable Na(v)1.5 protein expression from the wild-type allele correlates with the penetrance of cardiac conduction disease in the Scn5a(+/-) mouse model. PLoS One (2010) 1.26
Comparative demographics of the European cystic fibrosis population: a cross-sectional database analysis. Lancet (2010) 1.22
Mechanistic insight into control of CFTR by AMPK. J Biol Chem (2008) 1.21
Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation. Autophagy (2014) 1.21
Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/- murine hearts modelling the Brugada syndrome. J Physiol (2007) 1.19
Involvement of the anion exchanger SLC26A6 in prostaglandin E2- but not forskolin-stimulated duodenal HCO3- secretion. Gastroenterology (2006) 1.17
Binding of (-)-[3H]-CGP12177 at two sites in recombinant human beta 1-adrenoceptors and interaction with beta-blockers. Naunyn Schmiedebergs Arch Pharmacol (2004) 1.12
Liquid secretion inhibitors reduce mucociliary transport in glandular airways. Am J Physiol Lung Cell Mol Physiol (2002) 1.10
Paced electrogram fractionation analysis of arrhythmogenic tendency in DeltaKPQ Scn5a mice. J Cardiovasc Electrophysiol (2005) 1.10
Expression of wild-type CFTR suppresses NF-kappaB-driven inflammatory signalling. PLoS One (2010) 1.08
The orphan adhesion-GPCR GPR126 is required for embryonic development in the mouse. PLoS One (2010) 1.06
MDM2 SNP309 is associated with high grade node positive breast tumours and is in linkage disequilibrium with a novel MDM2 intron 1 polymorphism. BMC Cancer (2008) 1.06
Effects of L-type Ca2+ channel antagonism on ventricular arrhythmogenesis in murine hearts containing a modification in the Scn5a gene modelling human long QT syndrome 3. J Physiol (2006) 1.05
Comparative analysis of Cystic Fibrosis Registry data from the UK with USA, France and Australasia. J Cyst Fibros (2005) 1.05
Visualizing chromosomes as transcriptome correlation maps: evidence of chromosomal domains containing co-expressed genes--a study of 130 invasive ductal breast carcinomas. Cancer Res (2005) 1.05
DeltaF508-CFTR causes constitutive NF-kappaB activation through an ER-overload response in cystic fibrosis lungs. Biol Chem (2002) 1.05
A functional analysis of mouse models of cardiac disease through metabolic profiling. J Biol Chem (2004) 1.04
Frequency-dependent recruitment of fast amino acid and slow neuropeptide neurotransmitter release controls gonadotropin-releasing hormone neuron excitability. J Neurosci (2011) 1.04
Cyclin A1 protein shows haplo-insufficiency for normal fertility in male mice. Reproduction (2004) 1.03
Intrinsic sympathomimetic activity of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta1-adrenoceptor in human atrium and recombinant receptors. Naunyn Schmiedebergs Arch Pharmacol (2003) 1.00
Clinical and sociodemographic study of vitiligo. Indian J Dermatol Venereol Leprol (2009) 0.99
Novel regulation of cystic fibrosis transmembrane conductance regulator (CFTR) channel gating by external chloride. J Biol Chem (2004) 0.99
Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/Delta murine hearts modelling long QT syndrome 3. J Physiol (2006) 0.98
Kisspeptin signaling is required for peripheral but not central stimulation of gonadotropin-releasing hormone neurons by NMDA. J Neurosci (2010) 0.98
Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect functional links with cystic fibrosis pathogenesis. Biochemistry (2008) 0.98
Cystic fibrosis across Europe: EuroCareCF analysis of demographic data from 35 countries. J Cyst Fibros (2010) 0.98
Murine model of autosomal dominant retinitis pigmentosa generated by targeted deletion at codon 307 of the rds-peripherin gene. Hum Mol Genet (2002) 0.96
CFTR: a hub for kinases and crosstalk of cAMP and Ca2+. FEBS J (2013) 0.95
Regulation of the epithelial Na+ channel by the protein kinase CK2. J Biol Chem (2008) 0.95
The formation of the cAMP/protein kinase A-dependent annexin 2-S100A10 complex with cystic fibrosis conductance regulator protein (CFTR) regulates CFTR channel function. Mol Biol Cell (2007) 0.95
International Union of Basic and Clinical Pharmacology. LXXVII. Kisspeptin receptor nomenclature, distribution, and function. Pharmacol Rev (2010) 0.95
Kisspeptin-GPR54 signaling in mouse NO-synthesizing neurons participates in the hypothalamic control of ovulation. J Neurosci (2012) 0.95
Newborn screening for cystic fibrosis is associated with reduced treatment intensity. J Pediatr (2005) 0.95
Inhibition of protein kinase CK2 closes the CFTR Cl channel, but has no effect on the cystic fibrosis mutant deltaF508-CFTR. Cell Physiol Biochem (2009) 0.94
Splenomegaly and modified erythropoiesis in KLF13-/- mice. J Biol Chem (2008) 0.92
Inhibition of human bladder tumour cell growth by fibroblast growth factor receptor 2b is independent of its kinase activity. Involvement of the carboxy-terminal region of the receptor. Oncogene (2004) 0.92
Making human nasal cilia beat in the cold: a real time assay for cell signalling. Cell Signal (2003) 0.92
Characterization and functional study of a cluster of four highly conserved orphan adhesion-GPCR in mouse. Dev Dyn (2012) 0.92
The phosphorylation status of membrane-bound nucleoside diphosphate kinase in epithelia and the role of AMP. Mol Cell Biochem (2009) 0.91
Peroxisome proliferator-activated receptor-delta genotype influences metabolic phenotype and may influence lipid response to statin therapy in humans: a genetics of diabetes audit and research Tayside study. J Clin Endocrinol Metab (2010) 0.90
Nucleoside diphosphate kinase A as a controller of AMP-kinase in airway epithelia. J Bioenerg Biomembr (2006) 0.90
The European Cystic Fibrosis Society Patient Registry: valuable lessons learned on how to sustain a disease registry. Orphanet J Rare Dis (2014) 0.90
Mll5 is required for normal spermatogenesis. PLoS One (2011) 0.89
Ancestral haplotype 8.1 and lung disease severity in European cystic fibrosis patients. J Cyst Fibros (2011) 0.88
Comparison of protein transduction domains in mediating cell delivery of a secreted CRE protein. Biochemistry (2008) 0.87
Retracted Protein kinase CK2, cystic fibrosis transmembrane conductance regulator, and the deltaF508 mutation: F508 deletion disrupts a kinase-binding site. J Biol Chem (2007) 0.87
CFTR gene transfer to human cystic fibrosis pancreatic duct cells using a Sendai virus vector. J Cell Physiol (2008) 0.87
Retracted A novel physical and functional association between nucleoside diphosphate kinase A and AMP-activated protein kinase alpha1 in liver and lung. Biochem J (2005) 0.87
Contribution of casein kinase 2 and spleen tyrosine kinase to CFTR trafficking and protein kinase A-induced activity. Mol Cell Biol (2011) 0.87
The functional consequence of the Glu298Asp polymorphism of the endothelial nitric oxide synthase gene in young healthy volunteers. Cardiovasc Drug Rev (2007) 0.87
Neonatal screening for cystic fibrosis is beneficial even in the context of modern treatment. J Pediatr (2005) 0.86
Kisspeptin neurons co-express met-enkephalin and galanin in the rostral periventricular region of the female mouse hypothalamus. J Comp Neurol (2011) 0.86
Gpr54-/- mice show more pronounced defects in spermatogenesis than Kiss1-/- mice and improved spermatogenesis with age when exposed to dietary phytoestrogens. Reproduction (2010) 0.85
Delayed diagnosis of females with respiratory presentation of cystic fibrosis did not segregate with poorer clinical outcome. J Clin Epidemiol (2006) 0.85
Asians with cystic fibrosis in the UK have worse disease outcomes than clinic matched white homozygous delta F508 controls. J Cyst Fibros (2005) 0.85
Detection of phospho-sites generated by protein kinase CK2 in CFTR: mechanistic aspects of Thr1471 phosphorylation. PLoS One (2013) 0.85
Dictyostelium discoideum nucleoside diphosphate kinase C plays a negative regulatory role in phagocytosis, macropinocytosis and exocytosis. PLoS One (2011) 0.84
Stomatin immunoreactivity in ciliated cells of the human airway epithelium. Anat Embryol (Berl) (2003) 0.84
Retracted Understanding the molecular basis of the interaction between NDPK-A and AMPK alpha 1. Mol Cell Biol (2006) 0.84
Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2. Biochem J (2010) 0.84
A single nucleotide polymorphism on exon-4 of the gene encoding PPARdelta is associated with reduced height in adults and children. J Clin Endocrinol Metab (2009) 0.83
NDPK-A (but not NDPK-B) and AMPK alpha1 (but not AMPK alpha2) bind the cystic fibrosis transmembrane conductance regulator in epithelial cell membranes. Cell Signal (2006) 0.83
Reference percentiles for FEV(1) and BMI in European children and adults with cystic fibrosis. Orphanet J Rare Dis (2012) 0.83
X-ray microanalysis of airway surface liquid in the mouse. Am J Physiol Lung Cell Mol Physiol (2004) 0.83
Overweight and obesity in deltaF508 homozygous cystic fibrosis. J Pediatr (2005) 0.82
Ducts isolated from the pancreas of CFTR-null mice secrete fluid. Pflugers Arch (2009) 0.82
The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent. BMC Genomics (2011) 0.82
Role of binding and nucleoside diphosphate kinase A in the regulation of the cystic fibrosis transmembrane conductance regulator by AMP-activated protein kinase. J Biol Chem (2012) 0.81
4alpha-Phorbol negates the inhibitory effects of phorbol-12-myristate-13-acetate on human cilia and alters the phosphorylation of PKC. FEBS Lett (2002) 0.81
A methodology to establish a database to study gene environment interactions for childhood asthma. BMC Med Res Methodol (2010) 0.81
Origins of chemical evolution. Acc Chem Res (2012) 0.81
Small interfering peptide (siP) for in vivo examination of the developing lung interactonome. Dev Dyn (2009) 0.81
The NM23-H1/H2 homolog NDK-1 is required for full activation of Ras signaling in C. elegans. Development (2013) 0.80
Global array-based transcriptomics from minimal input RNA utilising an optimal RNA isolation process combined with SPIA cDNA probes. PLoS One (2011) 0.80