Overexpression of heparanase lowers the amyloid burden in amyloid-β precursor protein transgenic mice.

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Published in J Biol Chem on December 29, 2014

Authors

Charlotte B Jendresen1, Hao Cui2, Xiao Zhang3, Israel Vlodavsky4, Lars N G Nilsson5, Jin-Ping Li6

Author Affiliations

1: From the Department of Pharmacology, University of Oslo and Oslo University Hospital, Postboks 1057 Blindern, 0316 Oslo, Norway.
2: the Department of Medical Biochemistry and Microbiology, SciLifeLab Uppsala, The Biomedical Center, University of Uppsala, Box 582, Husargatan 3, 75123 Uppsala, Sweden.
3: the Department of Neuroscience and Pharmacology, University of Uppsala, Box 593, Husargatan 3, 75124 Uppsala, Sweden, and.
4: the Cancer and Vascular Biology Research Center Rappaport, Faculty of Medicine, Technion, P.O. Box 9649, 31096 Haifa, Israel.
5: From the Department of Pharmacology, University of Oslo and Oslo University Hospital, Postboks 1057 Blindern, 0316 Oslo, Norway, lars.nilsson@medisin.uio.no.
6: the Department of Medical Biochemistry and Microbiology, SciLifeLab Uppsala, The Biomedical Center, University of Uppsala, Box 582, Husargatan 3, 75123 Uppsala, Sweden, jin-ping.li@imbim.uu.se.

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