Gene expression changes in spinal motoneurons of the SOD1(G93A) transgenic model for ALS after treatment with G-CSF.

PubWeight™: 0.92‹?›

🔗 View Article (PMC 4299451)

Published in Front Cell Neurosci on January 20, 2015

Authors

Alexandre Henriques1, Stefan Kastner2, Eva Chatzikonstantinou2, Claudia Pitzer2, Christian Plaas2, Friederike Kirsch2, Oliver Wafzig2, Carola Krüger2, Robert Spoelgen2, Jose-Luis Gonzalez De Aguilar1, Norbert Gretz3, Armin Schneider2

Author Affiliations

1: INSERM, U1118, Mécanismes Centraux et Péripheriques de la Neurodégénérescence Strasbourg, France ; UMRS1118, Fédération de Médecine Translationnelle de Strasbourg Université de Strasbourg, France.
2: Sygnis Bioscience GmbH & Co KG Heidelberg, Germany.
3: Medical Research Center, Medical Faculty Mannheim, University of Heidelberg Mannheim, Germany.

Articles cited by this

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation. Science (1994) 18.08

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. J Neurosci (2008) 17.27

WebGestalt: an integrated system for exploring gene sets in various biological contexts. Nucleic Acids Res (2005) 12.88

WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013. Nucleic Acids Res (2013) 6.17

Activating transcription factor 3 (ATF3) induction by axotomy in sensory and motoneurons: A novel neuronal marker of nerve injury. Mol Cell Neurosci (2000) 3.73

Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis. Neuron (2013) 3.63

Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases. J Neurosci (2000) 3.14

Hypercaloric enteral nutrition in patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled phase 2 trial. Lancet (2014) 2.55

Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease. Lancet Neurol (2011) 2.34

Comparison of algorithms for the analysis of Affymetrix microarray data as evaluated by co-expression of genes in known operons. Nucleic Acids Res (2006) 2.24

Delayed systemic Nogo-66 receptor antagonist promotes recovery from spinal cord injury. J Neurosci (2003) 2.23

The Ccr4--not complex. Gene (2011) 2.08

Small proline-rich repeat protein 1A is expressed by axotomized neurons and promotes axonal outgrowth. J Neurosci (2002) 2.01

Microarray analysis of the cellular pathways involved in the adaptation to and progression of motor neuron injury in the SOD1 G93A mouse model of familial ALS. J Neurosci (2007) 1.65

Bone morphogenetic protein type IA receptor signaling regulates postnatal osteoblast function and bone remodeling. J Biol Chem (2004) 1.62

Repeated courses of granulocyte colony-stimulating factor in amyotrophic lateral sclerosis: clinical and biological results from a prospective multicenter study. Muscle Nerve (2011) 1.54

Granulocyte-colony stimulating factor improves outcome in a mouse model of amyotrophic lateral sclerosis. Brain (2008) 1.40

Ketone body synthesis in the brain: possible neuroprotective effects. Prostaglandins Leukot Essent Fatty Acids (2004) 1.30

BMPR1a and BMPR1b signaling exert opposing effects on gliosis after spinal cord injury. J Neurosci (2010) 1.29

Astrocyte activation by fibroblast growth factor-1 and motor neuron apoptosis: implications for amyotrophic lateral sclerosis. J Neurochem (2005) 1.22

Amyotrophic Lateral Sclerosis: An update for 2013 Clinical Features, Pathophysiology, Management and Therapeutic Trials. Aging Dis (2013) 1.18

Mechanisms, models and biomarkers in amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener (2013) 1.16

Neurotrophic growth factors for the treatment of amyotrophic lateral sclerosis: where do we stand? Front Neurosci (2010) 1.12

1H-NMR-based metabolomic profiling of CSF in early amyotrophic lateral sclerosis. PLoS One (2010) 1.12

NGF and GDNF ameliorate the increase in ATF3 expression which occurs in dorsal root ganglion cells in response to peripheral nerve injury. Eur J Neurosci (2004) 1.09

CNS-targeted viral delivery of G-CSF in an animal model for ALS: improved efficacy and preservation of the neuromuscular unit. Mol Ther (2010) 1.08

La-related protein 4 binds poly(A), interacts with the poly(A)-binding protein MLLE domain via a variant PAM2w motif, and can promote mRNA stability. Mol Cell Biol (2010) 1.02

Importin-beta11 regulates synaptic phosphorylated mothers against decapentaplegic, and thereby influences synaptic development and function at the Drosophila neuromuscular junction. J Neurosci (2010) 1.01

No widespread induction of cell death genes occurs in pure motoneurons in an amyotrophic lateral sclerosis mouse model. Hum Mol Genet (2005) 1.01

KCNQ5 channels control resting properties and release probability of a synapse. Nat Neurosci (2011) 1.00

RNA-Seq profiling of spinal cord motor neurons from a presymptomatic SOD1 ALS mouse. PLoS One (2013) 0.98

Molecular cloning and characterization of chemokine-like factor 1 (CKLF1), a novel human cytokine with unique structure and potential chemotactic activity. Biochem J (2001) 0.98

Stem-cell transplantation into the frontal motor cortex in amyotrophic lateral sclerosis patients. Cytotherapy (2009) 0.97

Expression of the regeneration-associated protein SPRR1A in primary sensory neurons and spinal cord of the adult mouse following peripheral and central injury. J Comp Neurol (2009) 0.97

Activating transcription factor 3 induction in sympathetic neurons after axotomy: response to decreased neurotrophin availability. Neuroscience (2007) 0.97

Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis. J Neuroinflammation (2011) 0.96

Impaired sprouting and axonal atrophy in cerebellar climbing fibres following in vivo silencing of the growth-associated protein GAP-43. PLoS One (2011) 0.95

Recombinant human granulocyte-colony stimulating factor administration for treating amyotrophic lateral sclerosis: A pilot study. Amyotroph Lateral Scler (2010) 0.95

Preliminary investigation of effect of granulocyte colony stimulating factor on amyotrophic lateral sclerosis. Amyotroph Lateral Scler (2009) 0.95

G-CSF prevents the progression of structural disintegration of white matter tracts in amyotrophic lateral sclerosis: a pilot trial. PLoS One (2011) 0.95

Can transcriptomics cut the gordian knot of amyotrophic lateral sclerosis? Curr Genomics (2011) 0.94

BMP signaling specifies the development of a large and fast CNS synapse. Nat Neurosci (2013) 0.94

Chondrolectin affects cell survival and neuronal outgrowth in in vitro and in vivo models of spinal muscular atrophy. Hum Mol Genet (2013) 0.93

Gender-Specific Mechanism of Synaptic Impairment and Its Prevention by GCSF in a Mouse Model of ALS. Front Cell Neurosci (2011) 0.92

A plural role for lipids in motor neuron diseases: energy, signaling and structure. Front Cell Neurosci (2014) 0.91

High-caloric food supplements in the treatment of amyotrophic lateral sclerosis: a prospective interventional study. Amyotroph Lateral Scler Frontotemporal Degener (2013) 0.90

Immunolocalization of a novel collectin CL-K1 in murine tissues. J Histochem Cytochem (2007) 0.89

The functional analysis of the CHMP2B missense mutation associated with neurodegenerative diseases in the endo-lysosomal pathway. Biochem Biophys Res Commun (2012) 0.88

Pegfilgrastim for PBSC mobilization and autologous haematopoietic SCT. Bone Marrow Transplant (2009) 0.87

Are BMPs involved in normal nerve and following transection?: a pilot study. Clin Orthop Relat Res (2009) 0.86

G-CSF protects motoneurons against axotomy-induced apoptotic death in neonatal mice. BMC Neurosci (2010) 0.85

The conserved P body component HPat/Pat1 negatively regulates synaptic terminal growth at the larval Drosophila neuromuscular junction. J Cell Sci (2012) 0.84

Biological functions of the novel collectins CL-L1, CL-K1, and CL-P1. J Biomed Biotechnol (2012) 0.84

Involvement of cathepsin B in the motor neuron degeneration of amyotrophic lateral sclerosis. Acta Neuropathol (2003) 0.83

Progenitor cell mobilization after exercise is related to systemic levels of G-CSF and muscle damage. Scand J Med Sci Sports (2014) 0.81

Acidic fibroblast growth factor prevents post-axotomy neuronal death of the newborn rat facial nerve. Neurosci Lett (1995) 0.81

Meta-analysis of gene expression profiling in amyotrophic lateral sclerosis: a comparison between transgenic mouse models and human patients. Amyotroph Lateral Scler Frontotemporal Degener (2013) 0.80

Upregulated expression of GAP-43 mRNA and protein in anterior horn motoneurons of the spinal cord after brachial plexus injury. Arch Med Res (2010) 0.79

Chondrolectin mediates growth cone interactions of motor axons with an intermediate target. J Neurosci (2012) 0.79

The expression of a motoneuron-specific serine protease, motopsin (PRSS12), after facial nerve axotomy in mice. J Plast Reconstr Aesthet Surg (2006) 0.78

Prevention of chemotherapy-induced neutropenia with pegfilgrastim: pharmacokinetics and patient outcomes. Chemotherapy (2012) 0.78

Inflammation enhances Y1 receptor signaling, neuropeptide Y-mediated inhibition of hyperalgesia, and substance P release from primary afferent neurons. Neuroscience (2013) 0.78

The expression changes of vacuolar protein sorting 4B (VPS4B) following middle cerebral artery occlusion (MCAO) in adult rats brain hippocampus. Cell Mol Neurobiol (2014) 0.76