Published in J Neurosci on January 02, 2008
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FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism. Cell (2011) 8.46
Astrocytes: biology and pathology. Acta Neuropathol (2009) 8.43
Molecular dissection of reactive astrogliosis and glial scar formation. Trends Neurosci (2009) 7.15
Functional organization of the transcriptome in human brain. Nat Neurosci (2008) 7.02
Global epigenomic reconfiguration during mammalian brain development. Science (2013) 6.14
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science (2014) 6.09
An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex. J Neurosci (2014) 5.52
Millisecond-timescale optical control of neural dynamics in the nonhuman primate brain. Neuron (2009) 5.50
Pericytes are required for blood-brain barrier integrity during embryogenesis. Nature (2010) 5.47
Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging. Neuron (2010) 5.20
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science (2013) 5.10
Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain. Cell Stem Cell (2008) 4.90
Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell (2011) 4.78
Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice. Science (2012) 4.14
Identification of a unique TGF-β-dependent molecular and functional signature in microglia. Nat Neurosci (2013) 3.94
Insulator dysfunction and oncogene activation in IDH mutant gliomas. Nature (2015) 3.64
Genomic analysis of reactive astrogliosis. J Neurosci (2012) 3.62
Astrocytes from familial and sporadic ALS patients are toxic to motor neurons. Nat Biotechnol (2011) 3.45
Integrated brain circuits: astrocytic networks modulate neuronal activity and behavior. Annu Rev Physiol (2010) 3.38
Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination. Neuron (2010) 3.37
Glutamate-dependent neuroglial calcium signaling differs between young and adult brain. Science (2013) 3.35
Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses. Nat Neurosci (2012) 3.28
Transcriptional landscape of the prenatal human brain. Nature (2014) 3.05
Aging effects on DNA methylation modules in human brain and blood tissue. Genome Biol (2012) 3.05
Regulation of synaptic connectivity by glia. Nature (2010) 3.02
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Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways. Proc Natl Acad Sci U S A (2010) 2.85
Distinct stages of myelination regulated by gamma-secretase and astrocytes in a rapidly myelinating CNS coculture system. Neuron (2008) 2.74
What is the role of astrocyte calcium in neurophysiology? Neuron (2008) 2.70
Direct lineage conversions: unnatural but useful? Nat Biotechnol (2011) 2.69
Generation of oligodendroglial cells by direct lineage conversion. Nat Biotechnol (2013) 2.64
Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication. PLoS Biol (2013) 2.61
Directing astroglia from the cerebral cortex into subtype specific functional neurons. PLoS Biol (2010) 2.60
The astrocyte odyssey. Prog Neurobiol (2008) 2.58
The local transcriptome in the synaptic neuropil revealed by deep sequencing and high-resolution imaging. Neuron (2012) 2.53
Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells. Nat Biotechnol (2013) 2.53
Regional astrocyte allocation regulates CNS synaptogenesis and repair. Science (2012) 2.53
The stem cell potential of glia: lessons from reactive gliosis. Nat Rev Neurosci (2011) 2.49
Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo. Nature (2015) 2.47
Gene coexpression networks in human brain identify epigenetic modifications in alcohol dependence. J Neurosci (2012) 2.46
Emerging roles of astrocytes in neural circuit development. Nat Rev Neurosci (2013) 2.45
Developmental genetics of vertebrate glial-cell specification. Nature (2010) 2.44
MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain. Genome Res (2010) 2.44
Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways. Nature (2013) 2.43
Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice. Nat Neurosci (2014) 2.38
Rett syndrome astrocytes are abnormal and spread MeCP2 deficiency through gap junctions. J Neurosci (2009) 2.35
Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation. BMC Neurosci (2010) 2.34
Sweet sixteen for ANLS. J Cereb Blood Flow Metab (2011) 2.33
Large-scale cellular-resolution gene profiling in human neocortex reveals species-specific molecular signatures. Cell (2012) 2.29
Neurotoxic reactive astrocytes are induced by activated microglia. Nature (2017) 2.29
Age-dependent fate and lineage restriction of single NG2 cells. Development (2011) 2.29
Astrocytes and disease: a neurodevelopmental perspective. Genes Dev (2012) 2.28
Axon degeneration: molecular mechanisms of a self-destruction pathway. J Cell Biol (2012) 2.26
Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma. J Clin Invest (2011) 2.25
Evolution of the aging brain transcriptome and synaptic regulation. PLoS One (2008) 2.23
Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination. Cell (2009) 2.18
Norepinephrine controls astroglial responsiveness to local circuit activity. Neuron (2014) 2.17
Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling. Proc Natl Acad Sci U S A (2008) 2.17
Adult mouse cortical cell taxonomy revealed by single cell transcriptomics. Nat Neurosci (2016) 2.15
Systems cancer medicine: towards realization of predictive, preventive, personalized and participatory (P4) medicine. J Intern Med (2012) 2.13
A transcriptomic atlas of mouse neocortical layers. Neuron (2011) 2.08
Specification of transplantable astroglial subtypes from human pluripotent stem cells. Nat Biotechnol (2011) 2.07
The mouse blood-brain barrier transcriptome: a new resource for understanding the development and function of brain endothelial cells. PLoS One (2010) 2.06
Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes. Acta Neuropathol (2015) 2.04
Subcellular profiling reveals distinct and developmentally regulated repertoire of growth cone mRNAs. J Neurosci (2010) 2.02
A survey of human brain transcriptome diversity at the single cell level. Proc Natl Acad Sci U S A (2015) 1.98
Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas. PLoS One (2012) 1.93
Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. Cell (2013) 1.92
Neuregulin and BDNF induce a switch to NMDA receptor-dependent myelination by oligodendrocytes. PLoS Biol (2013) 1.92
Development of a method for the purification and culture of rodent astrocytes. Neuron (2011) 1.92
Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors. Nature (2012) 1.92
A developmental taxonomy of glioblastoma defined and maintained by MicroRNAs. Cancer Res (2011) 1.89
Astrocyte-encoded positional cues maintain sensorimotor circuit integrity. Nature (2014) 1.88
Rapid and robust generation of functional oligodendrocyte progenitor cells from epiblast stem cells. Nat Methods (2011) 1.85
Retinoid X receptor gamma signaling accelerates CNS remyelination. Nat Neurosci (2010) 1.84
Coexpression network analysis of neural tissue reveals perturbations in developmental processes in schizophrenia. Genome Res (2010) 1.83
CD140a identifies a population of highly myelinogenic, migration-competent and efficiently engrafting human oligodendrocyte progenitor cells. Nat Biotechnol (2011) 1.83
Oligodendrocyte-encoded HIF function couples postnatal myelination and white matter angiogenesis. Cell (2014) 1.83
Storage and uptake of D-serine into astrocytic synaptic-like vesicles specify gliotransmission. J Neurosci (2013) 1.82
Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture. Nat Methods (2015) 1.82
Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons. Cell Stem Cell (2013) 1.80
Neuroscience in the era of functional genomics and systems biology. Nature (2009) 1.80
Glial cells physiologically modulate clock neurons and circadian behavior in a calcium-dependent manner. Curr Biol (2011) 1.80
Glial scar borders are formed by newly proliferated, elongated astrocytes that interact to corral inflammatory and fibrotic cells via STAT3-dependent mechanisms after spinal cord injury. J Neurosci (2013) 1.79
Glioblastoma models reveal the connection between adult glial progenitors and the proneural phenotype. PLoS One (2011) 1.77
Canonical genetic signatures of the adult human brain. Nat Neurosci (2015) 1.76
Excitability and synaptic communication within the oligodendrocyte lineage. J Neurosci (2010) 1.74
5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary. Nat Struct Mol Biol (2012) 1.74
Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity. Proc Natl Acad Sci U S A (2012) 1.74
Decoding signaling and function of the orphan G protein-coupled receptor GPR17 with a small-molecule agonist. Sci Signal (2013) 1.71
A genetically targeted optical sensor to monitor calcium signals in astrocyte processes. Nat Neurosci (2010) 1.71
Neuromodulation by extracellular ATP and P2X receptors in the CNS. Neuron (2012) 1.70
Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity. Mol Cancer Ther (2010) 1.69
MEK Is a Key Regulator of Gliogenesis in the Developing Brain. Neuron (2012) 1.68
Three mechanisms assemble central nervous system nodes of Ranvier. Neuron (2013) 1.68
TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3. Nat Neurosci (2011) 1.67
Specification and morphogenesis of astrocytes. Science (2010) 1.67
Regulation of oligodendrocyte development and myelination by glucose and lactate. J Neurosci (2011) 1.67
Integration of genome-wide approaches identifies lncRNAs of adult neural stem cells and their progeny in vivo. Cell Stem Cell (2013) 1.66
The classical complement cascade mediates CNS synapse elimination. Cell (2007) 9.06
Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis. Cell (2005) 7.41
Detection of splice junctions from paired-end RNA-seq data by SpliceMap. Nucleic Acids Res (2010) 6.95
Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner. Neuron (2012) 5.84
Pericytes are required for blood-brain barrier integrity during embryogenesis. Nature (2010) 5.47
Genomic analysis of reactive astrogliosis. J Neurosci (2012) 3.62
The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease. J Neurosci (2008) 3.62
Amacrine-signaled loss of intrinsic axon growth ability by retinal ganglion cells. Science (2002) 3.54
Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis. Cell (2009) 3.46
Architecture and activity-mediated refinement of axonal projections from a mosaic of genetically identified retinal ganglion cells. Neuron (2008) 3.41
Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination. Neuron (2010) 3.37
NGF controls axonal receptivity to myelination by Schwann cells or oligodendrocytes. Neuron (2004) 3.24
Wnt/beta-catenin signaling is required for CNS, but not non-CNS, angiogenesis. Proc Natl Acad Sci U S A (2009) 3.17
Genetic identification of an On-Off direction-selective retinal ganglion cell subtype reveals a layer-specific subcortical map of posterior motion. Neuron (2009) 3.13
Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain. Science (2014) 3.11
Regulation of synaptic connectivity by glia. Nature (2010) 3.02
Microglia: scapegoat, saboteur, or something else? Science (2013) 2.94
Exon arrays provide accurate assessments of gene expression. Genome Biol (2007) 2.86
ASAP: the Alternative Splicing Annotation Project. Nucleic Acids Res (2003) 2.83
Neuroscience: Glia - more than just brain glue. Nature (2009) 2.76
Distinct stages of myelination regulated by gamma-secretase and astrocytes in a rapidly myelinating CNS coculture system. Neuron (2008) 2.74
Assessing the impact of alternative splicing on domain interactions in the human proteome. J Proteome Res (2004) 2.71
Why is Wallerian degeneration in the CNS so slow? Annu Rev Neurosci (2007) 2.70
NS21: re-defined and modified supplement B27 for neuronal cultures. J Neurosci Methods (2008) 2.68
Astrocyte heterogeneity: an underappreciated topic in neurobiology. Curr Opin Neurobiol (2010) 2.68
Functional genomic analysis of oligodendrocyte differentiation. J Neurosci (2006) 2.64
Generation of oligodendroglial cells by direct lineage conversion. Nat Biotechnol (2013) 2.64
Signaling between glia and neurons: focus on synaptic plasticity. Curr Opin Neurobiol (2005) 2.62
Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors. Cell (2008) 2.60
Cross-hybridization modeling on Affymetrix exon arrays. Bioinformatics (2008) 2.54
The complement system: an unexpected role in synaptic pruning during development and disease. Annu Rev Neurosci (2012) 2.53
Structure and activity of putative intronic miRNA promoters. RNA (2010) 2.50
Nonallele-specific silencing of mutant and wild-type huntingtin demonstrates therapeutic efficacy in Huntington's disease mice. Mol Ther (2009) 2.47
Emerging roles of astrocytes in neural circuit development. Nat Rev Neurosci (2013) 2.45
An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition. EMBO J (2010) 2.42
Retinal ganglion cells do not extend axons by default: promotion by neurotrophic signaling and electrical activity. Neuron (2002) 2.41
Astrocytes and disease: a neurodevelopmental perspective. Genes Dev (2012) 2.28
Axon degeneration: molecular mechanisms of a self-destruction pathway. J Cell Biol (2012) 2.26
Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma. J Clin Invest (2011) 2.25
High dynamic range characterization of the trauma patient plasma proteome. Mol Cell Proteomics (2006) 2.25
A universal carrier test for the long tail of Mendelian disease. Reprod Biomed Online (2010) 2.21
Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination. Cell (2009) 2.18
Role for glia in synaptogenesis. Glia (2004) 2.15
MATS: a Bayesian framework for flexible detection of differential alternative splicing from RNA-Seq data. Nucleic Acids Res (2012) 2.09
A comparison of RNA-Seq and high-density exon array for detecting differential gene expression between closely related species. Nucleic Acids Res (2010) 2.07
The mouse blood-brain barrier transcriptome: a new resource for understanding the development and function of brain endothelial cells. PLoS One (2010) 2.06
Mammalian inscuteable regulates spindle orientation and cell fate in the developing retina. Neuron (2005) 2.06
Apelin, the ligand for the endothelial G-protein-coupled receptor, APJ, is a potent angiogenic factor required for normal vascular development of the frog embryo. Dev Biol (2006) 2.04
Global analysis of alternative splicing differences between humans and chimpanzees. Genes Dev (2007) 2.00
Evidence for a subpopulation of conserved alternative splicing events under selection pressure for protein reading frame preservation. Nucleic Acids Res (2004) 1.93
Development of a method for the purification and culture of rodent astrocytes. Neuron (2011) 1.92
Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors. Nature (2012) 1.92
Between the sheets: a molecular sieve makes myelin membranes. Dev Cell (2011) 1.87
Importance of intrinsic mechanisms in cell fate decisions in the developing rat retina. Neuron (2003) 1.86
Assessing the conservation of mammalian gene expression using high-density exon arrays. Mol Biol Evol (2007) 1.81
Transgenic mice reveal unexpected diversity of on-off direction-selective retinal ganglion cell subtypes and brain structures involved in motion processing. J Neurosci (2011) 1.77
Hedgehog signaling is essential for endothelial tube formation during vasculogenesis. Development (2004) 1.74
Neuronal pentraxins mediate synaptic refinement in the developing visual system. J Neurosci (2006) 1.71
Cadherin-6 mediates axon-target matching in a non-image-forming visual circuit. Neuron (2011) 1.67
Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC. Proc Natl Acad Sci U S A (2011) 1.65
Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling. Genes Dev (2008) 1.63
Human transcriptome array for high-throughput clinical studies. Proc Natl Acad Sci U S A (2011) 1.62
Novel functions of the phosphatidylinositol metabolic pathway discovered by a chemical genomics screen with wortmannin. Proc Natl Acad Sci U S A (2003) 1.61
Thrombospondins 1 and 2 are necessary for synaptic plasticity and functional recovery after stroke. J Cereb Blood Flow Metab (2008) 1.59
The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events. RNA Biol (2009) 1.57
LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival. Nat Med (2002) 1.57
Transcriptome-wide analyses of CstF64-RNA interactions in global regulation of mRNA alternative polyadenylation. Proc Natl Acad Sci U S A (2012) 1.54
Diverse splicing patterns of exonized Alu elements in human tissues. PLoS Genet (2008) 1.52
Fluorescent proteins expressed in mouse transgenic lines mark subsets of glia, neurons, macrophages, and dendritic cells for vital examination. J Neurosci (2004) 1.51
Cell adhesion molecules in synapse formation. J Neurosci (2004) 1.50
Genome-wide determination of a broad ESRP-regulated posttranscriptional network by high-throughput sequencing. Mol Cell Biol (2012) 1.49
Depolarization and CaM kinase IV modulate NMDA receptor splicing through two essential RNA elements. PLoS Biol (2007) 1.49
BMP-mediated specification of the erythroid lineage suppresses endothelial development in blood island precursors. Blood (2013) 1.48
MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes. PLoS Biol (2013) 1.45
A novel purification method for CNS projection neurons leads to the identification of brain vascular cells as a source of trophic support for corticospinal motor neurons. J Neurosci (2008) 1.44
Adenosine deamination in human transcripts generates novel microRNA binding sites. Hum Mol Genet (2009) 1.43
Widespread establishment and regulatory impact of Alu exons in human genes. Proc Natl Acad Sci U S A (2011) 1.40
Myocardin is sufficient and necessary for cardiac gene expression in Xenopus. Development (2005) 1.37
A dramatic increase of C1q protein in the CNS during normal aging. J Neurosci (2013) 1.35
APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex. Nature (2010) 1.35
Nebulin regulates actin filament lengths by a stabilization mechanism. J Cell Biol (2010) 1.35
Endogenous antibodies promote rapid myelin clearance and effective axon regeneration after nerve injury. Proc Natl Acad Sci U S A (2010) 1.34
Biology and pathology of nonmyelinating Schwann cells. Glia (2008) 1.33
Census of vertebrate Wnt genes: isolation and developmental expression of Xenopus Wnt2, Wnt3, Wnt9a, Wnt9b, Wnt10a, and Wnt16. Dev Dyn (2007) 1.28
Non-canonical Wnt signaling through Wnt5a/b and a novel Wnt11 gene, Wnt11b, regulates cell migration during avian gastrulation. Dev Biol (2008) 1.28
An oligodendrocyte lineage-specific semaphorin, Sema5A, inhibits axon growth by retinal ganglion cells. J Neurosci (2004) 1.27
Wnt11-R, a protein closely related to mammalian Wnt11, is required for heart morphogenesis in Xenopus. Dev Biol (2005) 1.26
Large-scale multiplexed quantitative discovery proteomics enabled by the use of an (18)O-labeled "universal" reference sample. J Proteome Res (2009) 1.24
Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase. Mol Genet Metab (2007) 1.24