The melanocyte lineage in development and disease.

PubWeight™: 1.11‹?› | Rank: Top 10%

🔗 View Article (PMC 4325379)

Published in Development on February 15, 2015

Authors

Richard L Mort1, Ian J Jackson2, E Elizabeth Patton3

Author Affiliations

1: MRC Human Genetics Unit and.
2: MRC Human Genetics Unit and University of Edinburgh Cancer Research UK Cancer Centre, MRC Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK ian.jackson@igmm.ed.ac.uk.
3: MRC Human Genetics Unit and Roslin Institute, University of Edinburgh, Edinburgh EH25 9RG, UK.

Articles citing this

MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment. Nat Commun (2015) 1.01

Signaling Pathways in Melanogenesis. Int J Mol Sci (2016) 0.87

From melanocytes to melanomas. Nat Rev Cancer (2016) 0.85

Over-expression of Plk4 induces centrosome amplification, loss of primary cilia and associated tissue hyperplasia in the mouse. Open Biol (2015) 0.83

Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model. Nat Commun (2016) 0.79

Serpine2, a potential novel target for combating melanoma metastasis. Am J Transl Res (2016) 0.78

Human neural crest cells contribute to coat pigmentation in interspecies chimeras after in utero injection into mouse embryos. Proc Natl Acad Sci U S A (2016) 0.78

Functional Characterization of MC1R-TUBB3 Intergenic Splice Variants of the Human Melanocortin 1 Receptor. PLoS One (2015) 0.76

Different growth and metastatic phenotypes associated with a cell-intrinsic change of Met in metastatic melanoma. Oncotarget (2016) 0.76

Evidence Supporting a Lymphatic Endothelium Origin for Angiomyolipoma, a TSC2(-) Tumor Related to Lymphangioleiomyomatosis. Am J Pathol (2016) 0.76

Muc1 promotes migration and lung metastasis of melanoma cells. Am J Cancer Res (2015) 0.76

Cellular and ultrastructural characterization of the grey-morph phenotype in southern right whales (Eubalaena australis). PLoS One (2017) 0.75

Melanoma and brown seaweed: an integrative hypothesis. J Appl Phycol (2016) 0.75

Deep-proteome mapping of WM-266-4 human metastatic melanoma cells: From oncogenic addiction to druggable targets. PLoS One (2017) 0.75

In the Wnt-er of life: Wnt signalling in melanoma and ageing. Br J Cancer (2016) 0.75

Rescue of neural crest-derived phenotypes in a zebrafish CHARGE model by Sox10 downregulation. Hum Mol Genet (2016) 0.75

Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin. Curr Biol (2017) 0.75

Chromatin immunoprecipitation and an open chromatin assay in zebrafish erythrocytes. Methods Cell Biol (2016) 0.75

Epilation induces hair and skin pigmentation through an EDN3/EDNRB-dependent regenerative response of melanocyte stem cells. Sci Rep (2017) 0.75

Regulatory Logic Underlying Diversification of the Neural Crest. Trends Genet (2017) 0.75

Melanoblast development coincides with the late emerging cells from the dorsal neural tube in turtle Trachemys scripta. Sci Rep (2017) 0.75

Identifying the niche controlling melanocyte differentiation. Genes Dev (2017) 0.75

SH3BP4, a novel pigmentation gene, is inversely regulated by miR-125b and MITF. Exp Mol Med (2017) 0.75

Articles cited by this

(truncated to the top 100)

Linking functional decline of telomeres, mitochondria and stem cells during ageing. Nature (2010) 5.02

Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma. Nature (2014) 4.88

nacre encodes a zebrafish microphthalmia-related protein that regulates neural-crest-derived pigment cell fate. Development (1999) 4.35

Dominant role of the niche in melanocyte stem-cell fate determination. Nature (2002) 4.05

The Development of Melanophores from Embryonic Mouse Tissues Grown in the Coelom of Chick Embryos. Proc Natl Acad Sci U S A (1940) 3.78

Melanocytes and the microphthalmia transcription factor network. Annu Rev Genet (2004) 3.78

Interferon-γ links ultraviolet radiation to melanomagenesis in mice. Nature (2011) 3.56

A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma. Nature (2011) 3.53

Control of cell behavior during vertebrate development by Slug, a zinc finger gene. Science (1994) 3.52

A melanocyte lineage program confers resistance to MAP kinase pathway inhibition. Nature (2013) 3.38

Mechanisms of hair graying: incomplete melanocyte stem cell maintenance in the niche. Science (2004) 3.12

Effects of G-protein mutations on skin color. Nat Genet (2004) 3.08

Actin dynamics at the leading edge: from simple machinery to complex networks. Dev Cell (2009) 3.06

Genotoxic stress abrogates renewal of melanocyte stem cells by triggering their differentiation. Cell (2009) 2.99

A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature (2011) 2.96

Interaction among SOX10, PAX3 and MITF, three genes altered in Waardenburg syndrome. Hum Mol Genet (2000) 2.63

Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia. J Cell Biol (2010) 2.62

Melanoma: from mutations to medicine. Genes Dev (2012) 2.59

Schwann cell precursors from nerve innervation are a cellular origin of melanocytes in skin. Cell (2009) 2.53

Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma. Oncogene (2011) 2.49

Gene control of mammalian pigmentary differentiation. I. Clonal origin of melanocytes. Proc Natl Acad Sci U S A (1967) 2.45

Cancer stem cells versus phenotype-switching in melanoma. Pigment Cell Melanoma Res (2010) 2.43

The temporal requirement for endothelin receptor-B signalling during neural crest development. Nature (1999) 2.42

Transcription factor hierarchy in Waardenburg syndrome: regulation of MITF expression by SOX10 and PAX3. Hum Genet (2000) 2.34

RAB7 controls melanoma progression by exploiting a lineage-specific wiring of the endolysosomal pathway. Cancer Cell (2014) 2.33

Frequent mutations in the MITF pathway in melanoma. Pigment Cell Melanoma Res (2009) 2.27

The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion. Curr Biol (2010) 2.23

Activation of the receptor tyrosine kinase Kit is required for the proliferation of melanoblasts in the mouse embryo. Dev Biol (1997) 2.20

P-Rex1 is required for efficient melanoblast migration and melanoma metastasis. Nat Commun (2011) 2.18

A cis-acting regulatory mutation causes premature hair graying and susceptibility to melanoma in the horse. Nat Genet (2008) 2.13

The Slug gene is not essential for mesoderm or neural crest development in mice. Dev Biol (1998) 2.13

The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development. Genes Dev (2003) 2.10

Key roles for transforming growth factor beta in melanocyte stem cell maintenance. Cell Stem Cell (2010) 2.06

The winged-helix transcription factor FoxD3 is important for establishing the neural crest lineage and repressing melanogenesis in avian embryos. Development (2001) 2.02

Fifteen-year quest for microphthalmia-associated transcription factor target genes. Pigment Cell Melanoma Res (2009) 2.01

Cofilin activity downstream of Pak1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks. Dev Cell (2007) 1.96

Coordinated activation of Wnt in epithelial and melanocyte stem cells initiates pigmented hair regeneration. Cell (2011) 1.92

Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells. J Cell Biol (2006) 1.86

Tamoxifen-inducible glia-specific Cre mice for somatic mutagenesis in oligodendrocytes and Schwann cells. Mol Cell Neurosci (2003) 1.84

Melanoblasts' proper location and timed differentiation depend on Notch/RBP-J signaling in postnatal hair follicles. J Invest Dermatol (2008) 1.83

Induction of melanocyte-specific microphthalmia-associated transcription factor by Wnt-3a. J Biol Chem (2000) 1.80

A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway. Cell (2013) 1.75

A conditional zebrafish MITF mutation reveals MITF levels are critical for melanoma promotion vs. regression in vivo. J Invest Dermatol (2013) 1.74

Deletion of the c-kit protooncogene in the human developmental defect piebald trait. Proc Natl Acad Sci U S A (1991) 1.72

Soluble and cell-bound forms of steel factor activity play distinct roles in melanocyte precursor dispersal and survival on the lateral neural crest migration pathway. Development (1995) 1.64

Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentation. Pigment Cell Melanoma Res (2011) 1.61

Role of hair follicles in the repigmentation of vitiligo. J Invest Dermatol (1991) 1.58

Ectopic expression of MITF, a gene for Waardenburg syndrome type 2, converts fibroblasts to cells with melanocyte characteristics. Nat Genet (1996) 1.58

The mutational spectrum in Waardenburg syndrome. Hum Mol Genet (1995) 1.55

SCF/c-kit signaling is required for cyclic regeneration of the hair pigmentation unit. FASEB J (2001) 1.54

Molecular characterization of melanocyte stem cells in their niche. Development (2005) 1.53

FOXD3 regulates the lineage switch between neural crest-derived glial cells and pigment cells by repressing MITF through a non-canonical mechanism. Development (2009) 1.52

Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently. Mech Dev (1998) 1.49

Human dermal stem cells differentiate into functional epidermal melanocytes. J Cell Sci (2010) 1.48

Hair follicle stem cells provide a functional niche for melanocyte stem cells. Cell Stem Cell (2011) 1.48

Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma. Nat Cell Biol (2012) 1.48

Small molecule-induced ablation and subsequent regeneration of larval zebrafish melanocytes. Development (2006) 1.47

Transgene expression of steel factor in the basal layer of epidermis promotes survival, proliferation, differentiation and migration of melanocyte precursors. Development (1998) 1.44

Interplay between Foxd3 and Mitf regulates cell fate plasticity in the zebrafish neural crest. Dev Biol (2010) 1.44

Timing and pattern of cell fate restrictions in the neural crest lineage. Development (1997) 1.44

Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner. Dev Dyn (2007) 1.40

Complex inheritance of melanoma and pigmentation of coat and skin in Grey horses. PLoS Genet (2013) 1.39

Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest. Development (2012) 1.37

Larval melanocyte regeneration following laser ablation in zebrafish. J Invest Dermatol (2004) 1.35

The migratory pathway of neural crest cells into the skin of mouse embryos. Dev Biol (1973) 1.34

Proliferation, dispersal and patterned aggregation of iridophores in the skin prefigure striped colouration of zebrafish. Nat Cell Biol (2014) 1.34

Neural crest cell migratory pathways in the trunk of the chick embryo. Dev Biol (1987) 1.32

The endothelin receptor-B is required for the migration of neural crest-derived melanocyte and enteric neuron precursors. Dev Biol (2003) 1.32

Melanocytes in development, regeneration, and cancer. Cell Stem Cell (2008) 1.31

NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche. Nature (2013) 1.29

Neural crest progenitors and stem cells: from early development to adulthood. Dev Biol (2012) 1.29

Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod- driven motility and cell-cycle progression. Dev Cell (2011) 1.29

Origin of pigment cells from the neural crest in the mouse embryo. Physiol Zool (1947) 1.28

Post-embryonic nerve-associated precursors to adult pigment cells: genetic requirements and dynamics of morphogenesis and differentiation. PLoS Genet (2011) 1.28

Histochemical survey of the distribution of the epidermal melanoblasts and melanocytes in the mouse during fetal and postnatal periods. Anat Rec (1984) 1.26

Wnt and BMP signaling govern lineage segregation of melanocytes in the avian embryo. Dev Biol (2001) 1.25

Senile hair graying: H2O2-mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair. FASEB J (2009) 1.25

The neural crest. Development (2013) 1.24

MGF (KIT ligand) is a chemokinetic factor for melanoblast migration into hair follicles. Dev Biol (2000) 1.23

Temporal control of neural crest lineage generation by Wnt/β-catenin signaling. Development (2012) 1.22

Foxd3 controls melanophore specification in the zebrafish neural crest by regulation of Mitf. Dev Biol (2009) 1.22

On the embryonic origin of adult melanophores: the role of ErbB and Kit signalling in establishing melanophore stem cells in zebrafish. Development (2013) 1.22

Pharmacologic interventions in aging hair. Clin Interv Aging (2006) 1.20

Microphthalmia-associated transcription factor controls the DNA damage response and a lineage-specific senescence program in melanomas. Cancer Res (2010) 1.20

Distinct stages of melanocyte differentiation revealed by anlaysis of nonuniform pigmentation patterns. Development (1996) 1.19

Temporal and molecular separation of the kit receptor tyrosine kinase's roles in zebrafish melanocyte migration and survival. Dev Biol (2003) 1.19

mitfa is required at multiple stages of melanocyte differentiation but not to establish the melanocyte stem cell. Dev Biol (2010) 1.19

Perivascular-resident macrophage-like melanocytes in the inner ear are essential for the integrity of the intrastrial fluid-blood barrier. Proc Natl Acad Sci U S A (2012) 1.18

Reversal of developmental restrictions in neural crest lineages: transition from Schwann cells to glial-melanocytic precursors in vitro. Proc Natl Acad Sci U S A (2003) 1.15

Melanoma, nevogenesis, and stem cell biology. J Invest Dermatol (2008) 1.15

Direct migration of follicular melanocyte stem cells to the epidermis after wounding or UVB irradiation is dependent on Mc1r signaling. Nat Med (2013) 1.15

Pigment patterns: fish in stripes and spots. Curr Biol (2003) 1.15

colgate/hdac1 Repression of foxd3 expression is required to permit mitfa-dependent melanogenesis. Dev Biol (2007) 1.14

Pmel17 expression is Mitf-dependent and reveals cranial melanoblast migration during murine development. Gene Expr Patterns (2003) 1.14

Evidence for a dynamic spatiotemporal fate map and early fate restrictions of premigratory avian neural crest. Development (2010) 1.14

Defects in ErbB-dependent establishment of adult melanocyte stem cells reveal independent origins for embryonic and regeneration melanocytes. PLoS Genet (2009) 1.11

Epidemiological and investigative study of premature graying of hair in higher secondary and pre-university school children. Int J Trichology (2013) 1.11

Mutations in MITF and PAX3 cause "splashed white" and other white spotting phenotypes in horses. PLoS Genet (2012) 1.11

Descriptive and experimental analysis of the dispersion of neural crest cells along the dorsolateral path and their entry into ectoderm in the chick embryo. Dev Biol (1992) 1.10

Mitf expression is sufficient to direct differentiation of medaka blastula derived stem cells to melanocytes. Development (2003) 1.09

Articles by these authors

The melanocyte lineage in development and disease. Development (2015) 0.81