Published in BMC Bioinformatics on February 23, 2015
Genome-wide analysis of microRNA and mRNA expression signatures in cancer. Acta Pharmacol Sin (2015) 0.86
Aberrant Wnt Signaling in Leukemia. Cancers (Basel) (2016) 0.77
DNA Methylation Events as Markers for Diagnosis and Management of Acute Myeloid Leukemia and Myelodysplastic Syndrome. Dis Markers (2017) 0.75
Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics (2003) 100.88
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics (2003) 82.89
Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet. Blood (2009) 15.95
Prognostically useful gene-expression profiles in acute myeloid leukemia. N Engl J Med (2004) 11.61
DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia. Cancer Cell (2010) 6.72
MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation. Blood (2009) 4.00
WNT signalling in the immune system: WNT is spreading its wings. Nat Rev Immunol (2008) 3.46
Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation. Blood (2008) 2.37
Canonical wnt signaling regulates hematopoiesis in a dosage-dependent fashion. Cell Stem Cell (2011) 2.18
RUNX1 mutations are associated with poor outcome in younger and older patients with cytogenetically normal acute myeloid leukemia and with distinct gene and MicroRNA expression signatures. J Clin Oncol (2012) 1.79
Genome-wide determination of DNA methylation by Hpa II tiny fragment enrichment by ligation-mediated PCR (HELP) for the study of acute leukemias. Methods Mol Biol (2009) 1.71
Tumor formation by genetic mutations in the components of the Wnt signaling pathway. Cancer Sci (2003) 1.42
Wnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia development. Leukemia (2011) 1.37
Acquired mutations in ASXL1 in acute myeloid leukemia: prevalence and prognostic value. Haematologica (2011) 1.30
Wnt signaling pathway is epigenetically regulated by methylation of Wnt antagonists in acute myeloid leukemia. Leukemia (2009) 1.29
High expression of lymphoid enhancer-binding factor-1 (LEF1) is a novel favorable prognostic factor in cytogenetically normal acute myeloid leukemia. Blood (2012) 1.21
Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells. J Clin Invest (2013) 1.20
Acute myeloid leukemia is characterized by Wnt pathway inhibitor promoter hypermethylation. Leuk Lymphoma (2010) 1.13
The effect of the proteasome inhibitor bortezomib on acute myeloid leukemia cells and drug resistance associated with the CD34+ immature phenotype. Haematologica (2008) 1.13
RUNX1 mutations in cytogenetically normal acute myeloid leukemia are associated with a poor prognosis and up-regulation of lymphoid genes. Haematologica (2012) 1.06
Epigenetic regulation of the non-canonical Wnt pathway in acute myeloid leukemia. Cancer Sci (2009) 1.01
Analysis of AML genes in dysregulated molecular networks. BMC Bioinformatics (2009) 0.93
Proteasomal non-catalytic subunit PSMD2 as a potential therapeutic target in association with various clinicopathologic features in lung adenocarcinomas. Mol Carcinog (2011) 0.91
Methylation of Wnt antagonist genes: a useful prognostic marker for myelodysplastic syndrome. Ann Hematol (2012) 0.89
Distinct association between aberrant methylation of Wnt inhibitors and genetic alterations in acute myeloid leukaemia. Br J Cancer (2011) 0.87
The Proteasome Inhibitor Bortezomib Sensitizes AML with Myelomonocytic Differentiation to TRAIL Mediated Apoptosis. Cancers (Basel) (2011) 0.79
Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients. J Clin Invest (2008) 7.05
Endothelial progenitor cell dysfunction: a novel concept in the pathogenesis of vascular complications of type 1 diabetes. Diabetes (2004) 4.24
Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy. J Clin Invest (2007) 3.28
An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas. Nat Genet (2005) 3.04
Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia. Cancer Cell (2011) 2.89
Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo. J Clin Invest (2007) 2.80
New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling. J Exp Med (2005) 2.44
Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation. Blood (2008) 2.37
Canonical wnt signaling regulates hematopoiesis in a dosage-dependent fashion. Cell Stem Cell (2011) 2.18
A protocol for building and evaluating predictors of disease state based on microarray data. Bioinformatics (2005) 2.08
An algorithm-based topographical biomaterials library to instruct cell fate. Proc Natl Acad Sci U S A (2011) 1.99
Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways. Blood (2006) 1.98
Fewer permutations, more accurate P-values. Bioinformatics (2009) 1.91
A discriminating messenger RNA signature for bipolar disorder formed by an aberrant expression of inflammatory genes in monocytes. Arch Gen Psychiatry (2008) 1.66
Chance or necessity? Insertional mutagenesis in gene therapy and its consequences. Mol Ther (2004) 1.65
Molecular classification of breast carcinomas by comparative genomic hybridization: a specific somatic genetic profile for BRCA1 tumors. Cancer Res (2002) 1.64
De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial biotechnology. Microb Cell Fact (2012) 1.62
Ig gene rearrangement steps are initiated in early human precursor B cell subsets and correlate with specific transcription factor expression. J Immunol (2005) 1.61
A comparison of univariate and multivariate gene selection techniques for classification of cancer datasets. BMC Bioinformatics (2006) 1.57
Pooling breast cancer datasets has a synergetic effect on classification performance and improves signature stability. BMC Genomics (2008) 1.45
Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis. Genome Res (2014) 1.40
Functional crosstalk between Bmi1 and MLL/Hoxa9 axis in establishment of normal hematopoietic and leukemic stem cells. Cell Stem Cell (2011) 1.33
Contrasting responses of lymphoid progenitors to canonical and noncanonical Wnt signals. J Immunol (2008) 1.29
Human thymus contains multipotent progenitors with T/B lymphoid, myeloid, and erythroid lineage potential. Blood (2005) 1.29
Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts. Blood (2011) 1.28
WISECONDOR: detection of fetal aberrations from shallow sequencing maternal plasma based on a within-sample comparison scheme. Nucleic Acids Res (2013) 1.28
MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1-regulated pathways in mice. Blood (2011) 1.26
Distinct monocyte gene-expression profiles in autoimmune diabetes. Diabetes (2008) 1.25
Wnt signaling in the thymus is regulated by differential expression of intracellular signaling molecules. Proc Natl Acad Sci U S A (2006) 1.24
Generic and specific transcriptional responses to different weak organic acids in anaerobic chemostat cultures of Saccharomyces cerevisiae. FEMS Yeast Res (2007) 1.19
Quantitative proteomics and transcriptomics of anaerobic and aerobic yeast cultures reveals post-transcriptional regulation of key cellular processes. Microbiology (2007) 1.18
Gene therapy: is IL2RG oncogenic in T-cell development? Nature (2006) 1.18
Microarray analysis reveals expression regulation of Wnt antagonists in differentiating osteoblasts. Bone (2005) 1.17
Canonical Wnt signaling negatively modulates regulatory T cell function. Immunity (2013) 1.13
The value of allogeneic and autologous hematopoietic stem cell transplantation in prognostically favorable acute myeloid leukemia with double mutant CEBPA. Blood (2013) 1.11
Morbidly obese human subjects have increased peripheral blood CD4+ T cells with skewing toward a Treg- and Th2-dominated phenotype. Diabetes (2012) 1.09
Age-related changes in the cellular composition of the thymus in children. J Allergy Clin Immunol (2005) 1.07
Combinatorial effects of environmental parameters on transcriptional regulation in Saccharomyces cerevisiae: a quantitative analysis of a compendium of chemostat-based transcriptome data. BMC Genomics (2009) 1.07
Endothelial progenitor cell dysfunction in type 1 diabetes: another consequence of oxidative stress? Antioxid Redox Signal (2005) 1.07
The nuclear effector of Wnt-signaling, Tcf1, functions as a T-cell-specific tumor suppressor for development of lymphomas. PLoS Biol (2012) 1.06
Integration of DNA copy number alterations and prognostic gene expression signatures in breast cancer patients. Clin Cancer Res (2010) 1.05
Wnt signaling and phosphorylation status of beta-catenin: importance of the correct antibody tools. Blood (2007) 1.03
Predicting metabolic fluxes using gene expression differences as constraints. IEEE/ACM Trans Comput Biol Bioinform (2010) 1.03
EVI1 is critical for the pathogenesis of a subset of MLL-AF9-rearranged AMLs. Blood (2012) 1.01
Exploiting combinatorial cultivation conditions to infer transcriptional regulation. BMC Genomics (2007) 1.00
New insights and unresolved issues regarding insertional mutagenesis in X-linked SCID gene therapy. Mol Ther (2007) 1.00
GRASS: a generic algorithm for scaffolding next-generation sequencing assemblies. Bioinformatics (2012) 1.00
De novo detection of copy number variation by co-assembly. Bioinformatics (2012) 0.99
CytoscapeRPC: a plugin to create, modify and query Cytoscape networks from scripting languages. Bioinformatics (2011) 0.98
Physiological and transcriptional responses of Saccharomyces cerevisiae to zinc limitation in chemostat cultures. Appl Environ Microbiol (2007) 0.98
T-sing progenitors to commit. Trends Immunol (2006) 0.97
Effects of Delta1 and Jagged1 on early human hematopoiesis: correlation with expression of notch signaling-related genes in CD34+ cells. Stem Cells (2006) 0.95
Dialysis-related systemic microinflammation is associated with specific genomic patterns. Nephrol Dial Transplant (2007) 0.93
Integration of clinical and gene expression data has a synergetic effect on predicting breast cancer outcome. PLoS One (2012) 0.93
Meta-analysis on blood transcriptomic studies identifies consistently coexpressed protein-protein interaction modules as robust markers of human aging. Aging Cell (2013) 0.93
Gene-expression profiling of CD34+ cells from various hematopoietic stem-cell sources reveals functional differences in stem-cell activity. J Leukoc Biol (2003) 0.92
Wnt3a nonredundantly controls hematopoietic stem cell function and its deficiency results in complete absence of canonical Wnt signaling. Blood (2010) 0.92
Module-based outcome prediction using breast cancer compendia. PLoS One (2007) 0.92
CD34+ cells home, proliferate, and participate in capillary formation, and in combination with CD34- cells enhance tube formation in a 3-dimensional matrix. Arterioscler Thromb Vasc Biol (2005) 0.90
The effect of oligonucleotide microarray data pre-processing on the analysis of patient-cohort studies. BMC Bioinformatics (2006) 0.89
Sign language recognition by combining statistical DTW and independent classification. IEEE Trans Pattern Anal Mach Intell (2008) 0.89
A scale-space method for detecting recurrent DNA copy number changes with analytical false discovery rate control. Nucleic Acids Res (2013) 0.89
Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors. PLoS One (2013) 0.88
Exploring variation-aware contig graphs for (comparative) metagenomics using MaryGold. Bioinformatics (2013) 0.88
Predicting the therapeutic efficacy of MSC in bone tissue engineering using the molecular marker CADM1. Biomaterials (2013) 0.88
Flt3 ligand expands lymphoid progenitors prior to recovery of thymopoiesis and accelerates T cell reconstitution after bone marrow transplantation. J Immunol (2007) 0.88
Metabolic pathway alignment between species using a comprehensive and flexible similarity measure. BMC Syst Biol (2008) 0.87
Introducing WISECONDOR for noninvasive prenatal diagnostics. Expert Rev Mol Diagn (2014) 0.86
Edge-based image restoration. IEEE Trans Image Process (2005) 0.85
Pattern recognition in bioinformatics. Brief Bioinform (2013) 0.85
CD4+ T-cell counts and interleukin-8 and CCL-5 plasma concentrations discriminate disease severity in children with RSV infection. Pediatr Res (2012) 0.85
A comprehensive sensitivity analysis of microarray breast cancer classification under feature variability. BMC Bioinformatics (2009) 0.84
Chimerism levels after stem cell transplantation are primarily determined by the ratio of donor to host stem cells. Blood (2011) 0.83
Integrating protein-protein interaction networks with gene-gene co-expression networks improves gene signatures for classifying breast cancer metastasis. J Integr Bioinform (2011) 0.82
Differential requirements for Wnt and Notch signaling in hematopoietic versus thymic niches. Ann N Y Acad Sci (2012) 0.82
Retroviral integration mutagenesis in mice and comparative analysis in human AML identify reduced PTP4A3 expression as a prognostic indicator. PLoS One (2011) 0.81
HAT: hypergeometric analysis of tiling-arrays with application to promoter-GeneChip data. BMC Bioinformatics (2010) 0.81
Integration of known transcription factor binding site information and gene expression data to advance from co-expression to co-regulation. Genomics Proteomics Bioinformatics (2007) 0.80
WNT proteins: environmental factors regulating HSC fate in the niche. Ann N Y Acad Sci (2009) 0.80
Profiling of antibody production against xenograft-released proteins by protein microarrays discovers prostate cancer markers. J Proteome Res (2011) 0.80
SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets. BMC Bioinformatics (2007) 0.80
An evaluation protocol for subtype-specific breast cancer event prediction. PLoS One (2011) 0.80
Exploring sequence characteristics related to high-level production of secreted proteins in Aspergillus niger. PLoS One (2012) 0.80
Analysis of mass spectrometry data using sub-spectra. BMC Bioinformatics (2009) 0.80
The nearest subclass classifier: a compromise between the nearest mean and nearest neighbor classifier. IEEE Trans Pattern Anal Mach Intell (2005) 0.80
Maximum significance clustering of oligonucleotide microarrays. Bioinformatics (2005) 0.78
Thyrotropin acts as a T-cell developmental factor in mice and humans. Thyroid (2014) 0.78
Integration of gene expression and DNA-methylation profiles improves molecular subtype classification in acute myeloid leukemia. BMC Bioinformatics (2015) 0.78
Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain. Blood (2010) 0.78
Alternative splicing and differential expression of the islet autoantigen IGRP between pancreas and thymus contributes to immunogenicity of pancreatic islets but not diabetogenicity in humans. Diabetologia (2013) 0.78
Wnt signaling in leukemias and myeloma: T-cell factors are in control. Future Oncol (2013) 0.78
Efficient calculation of compound similarity based on maximum common subgraphs and its application to prediction of gene transcript levels. Int J Bioinform Res Appl (2013) 0.77
Knowledge driven decomposition of tumor expression profiles. BMC Bioinformatics (2009) 0.77
Selective in vitro expansion and efficient retroviral transduction of human CD34+ CD38- haematopoietic stem cells. Br J Haematol (2002) 0.76