Published in PLoS Pathog on March 04, 2015
Pertussis: Microbiology, Disease, Treatment, and Prevention. Clin Microbiol Rev (2016) 1.07
Cyclic di-GMP modulates gene expression in Lyme disease spirochetes at the tick-mammal interface to promote spirochete survival during the blood meal and tick-to-mammal transmission. Infect Immun (2015) 0.86
Balance between Coiled-Coil Stability and Dynamics Regulates Activity of BvgS Sensor Kinase in Bordetella. MBio (2016) 0.79
Signal Transduction by BvgS Sensor Kinase: BINDING OF MODULATOR NICOTINATE AFFECTS THE CONFORMATION AND DYNAMICS OF THE ENTIRE PERIPLASMIC MOIETY. J Biol Chem (2015) 0.78
Glutamate Limitation, BvgAS Activation, and (p)ppGpp Regulate the Expression of the Bordetella pertussis Type 3 Secretion System. J Bacteriol (2015) 0.78
Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor: A system for sensing small molecules associated with tick feeding. J Struct Biol (2015) 0.77
Highlights of the 11th International Bordetella Symposium: from Basic Biology to Vaccine Development. Clin Vaccine Immunol (2016) 0.75
Bordetella PlrSR regulatory system controls BvgAS activity and virulence in the lower respiratory tract. Proc Natl Acad Sci U S A (2017) 0.75
Structural and functional analysis of the Escherichia coli acid-sensing histidine kinase, EvgS. J Bacteriol (2017) 0.75
Conformational Changes of an Interdomain Linker Mediate Mechanical Signal Transmission in Sensor Kinase BvgS. J Bacteriol (2017) 0.75
The BvgAS Regulon of Bordetella pertussis. MBio (2017) 0.75
Features and development of Coot. Acta Crystallogr D Biol Crystallogr (2010) 89.46
XDS. Acta Crystallogr D Biol Crystallogr (2010) 67.46
Inference of macromolecular assemblies from crystalline state. J Mol Biol (2007) 44.95
REFMAC5 for the refinement of macromolecular crystal structures. Acta Crystallogr D Biol Crystallogr (2011) 39.32
Molecular replacement with MOLREP. Acta Crystallogr D Biol Crystallogr (2009) 26.26
Two-component signal transduction. Annu Rev Biochem (2000) 19.12
Four new derivatives of the broad-host-range cloning vector pBBR1MCS, carrying different antibiotic-resistance cassettes. Gene (1995) 18.98
Towards automated crystallographic structure refinement with phenix.refine. Acta Crystallogr D Biol Crystallogr (2012) 11.31
X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor. Nature (2009) 6.81
Sequences required for expression of Bordetella pertussis virulence factors share homology with prokaryotic signal transduction proteins. Proc Natl Acad Sci U S A (1989) 4.78
Two trans-acting regulatory genes (vir and mod) control antigenic modulation in Bordetella pertussis. J Bacteriol (1988) 3.88
Sending signals dynamically. Science (2009) 3.64
Atomic structure and specificity of bacterial periplasmic receptors for active transport and chemotaxis: variation of common themes. Mol Microbiol (1996) 3.61
Spherically averaged phased translation function and its application to the search for molecules and fragments in electron-density maps. Acta Crystallogr D Biol Crystallogr (2001) 2.91
Phosphorelay control of virulence gene expression in Bordetella. Trends Microbiol (2003) 2.60
Mechanism of activation of protein kinase JAK2 by the growth hormone receptor. Science (2014) 2.52
Integration of multiple domains in a two-component sensor protein: the Bordetella pertussis BvgAS phosphorelay. EMBO J (1996) 2.41
Crystal structure of a heterotetrameric NMDA receptor ion channel. Science (2014) 2.22
Heptakis(2,6-O-dimethyl)beta-cyclodextrin: a novel growth stimulant for Bordetella pertussis phase I. J Clin Microbiol (1983) 2.17
Design of an expression system for detecting folded protein domains and mapping macromolecular interactions by NMR. Protein Sci (1997) 2.16
A mutation in the Bordetella bronchiseptica bvgS gene results in reduced virulence and increased resistance to starvation, and identifies a new class of Bvg-regulated antigens. Mol Microbiol (1997) 2.01
MiST: a microbial signal transduction database. Nucleic Acids Res (2006) 1.96
Bacterial virulence gene regulation: an evolutionary perspective. Annu Rev Microbiol (2000) 1.82
Escherichia coli gene expression responsive to levels of the response regulator EvgA. J Bacteriol (2002) 1.74
Two-component signal transduction as potential drug targets in pathogenic bacteria. Curr Opin Microbiol (2010) 1.74
Species- and strain-specific control of a complex, flexible regulon by Bordetella BvgAS. J Bacteriol (2006) 1.70
The mechanism of signal transduction by two-component systems. Curr Opin Struct Biol (2010) 1.61
HAMP domain conformers that propagate opposite signals in bacterial chemoreceptors. PLoS Biol (2013) 1.60
Mechanisms of Bordetella pathogenesis. Front Biosci (2001) 1.52
Identification and characterization of BipA, a Bordetella Bvg-intermediate phase protein. Mol Microbiol (2001) 1.47
Evolution and phyletic distribution of two-component signal transduction systems. Curr Opin Microbiol (2010) 1.47
Disulfide by Design: a computational method for the rational design of disulfide bonds in proteins. Bioinformatics (2003) 1.47
Regulation of the Ysa type III secretion system of Yersinia enterocolitica by YsaE/SycB and YsrS/YsrR. J Bacteriol (2004) 1.44
Bordetella pertussis pathogenesis: current and future challenges. Nat Rev Microbiol (2014) 1.40
New virulence-activated and virulence-repressed genes identified by systematic gene inactivation and generation of transcriptional fusions in Bordetella pertussis. J Bacteriol (2000) 1.29
Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines. EMBO J (2011) 1.28
Ligand-free and -bound structures of the binding protein (LivJ) of the Escherichia coli ABC leucine/isoleucine/valine transport system: trajectory and dynamics of the interdomain rotation and ligand specificity. Biochemistry (2005) 1.26
In vivo phosphorylation dynamics of the Bordetella pertussis virulence-controlling response regulator BvgA. Mol Microbiol (2013) 1.24
Automated real-space refinement of protein structures using a realistic backbone move set. Biophys J (2011) 1.16
Allosteric signaling and dynamics of the clamshell-like NMDA receptor GluN1 N-terminal domain. Nat Struct Mol Biol (2013) 1.14
P2CS: a database of prokaryotic two-component systems. Nucleic Acids Res (2010) 1.12
Characterization of environmental regulators of Bordetella pertussis. Infect Immun (1993) 1.12
Constitutive activation of the N-methyl-D-aspartate receptor via cleft-spanning disulfide bonds. J Biol Chem (2008) 1.10
A scissor blade-like closing mechanism implicated in transmembrane signaling in a Bacteroides hybrid two-component system. Proc Natl Acad Sci U S A (2012) 1.07
The hybrid histidine kinase Hk1 is part of a two-component system that is essential for survival of Borrelia burgdorferi in feeding Ixodes scapularis ticks. Infect Immun (2011) 1.07
Periplasmic domain of the sensor-kinase BvgS reveals a new paradigm for the Venus flytrap mechanism. Proc Natl Acad Sci U S A (2010) 1.01
The vibrio cholerae hybrid sensor kinase VieS contributes to motility and biofilm regulation by altering the cyclic diguanylate level. J Bacteriol (2008) 1.00
Two-component regulatory systems in Pseudomonas aeruginosa: an intricate network mediating fimbrial and efflux pump gene expression. Mol Microbiol (2011) 0.99
The role of two-component regulation systems in the physiology of the bacterial cell. Sci Prog (2006) 0.96
Identification of two bvg-repressed surface proteins of Bordetella pertussis. Infect Immun (1995) 0.95
Dimerization of signalling modules of the EvgAS and BvgAS phosphorelay systems. Biochim Biophys Acta (2000) 0.94
Integration of rotation and piston motions in coiled-coil signal transduction. J Bacteriol (2007) 0.93
Molecular evolution of the two-component system BvgAS involved in virulence regulation in Bordetella. PLoS One (2009) 0.93
Crystal structure of a histidine kinase sensor domain with similarity to periplasmic binding proteins. Proteins (2009) 0.91
Characterization of mutations in the PAS domain of the EvgS sensor kinase selected by laboratory evolution for acid resistance in Escherichia coli. Mol Microbiol (2014) 0.88
Characterization of the PAS domain in the sensor-kinase BvgS: mechanical role in signal transmission. BMC Microbiol (2013) 0.84
Conserved sequence motifs in the unorthodox BvgS two-component sensor protein of Bordetella pertussis. Mol Gen Genet (1996) 0.82
A new paradigm for hormone recognition and allosteric receptor activation revealed from structural studies of NPR-C. Peptides (2005) 0.78