Four crystal structures of human LLT1, a ligand of human NKR-P1, in varied glycosylation and oligomerization states.

PubWeight™: 0.75‹?›

🔗 View Article (PMC 4356368)

Published in Acta Crystallogr D Biol Crystallogr on February 26, 2015

Authors

Tereza Skálová1, Jan Bláha2, Karl Harlos3, Jarmila Dušková1, Tomáš Koval'4, Jan Stránský1, Jindřich Hašek1, Ondřej Vaněk2, Jan Dohnálek1

Author Affiliations

1: Institute of Biotechnology, Academy of Sciences of the Czech Republic, v.v.i., Vídeňská 1083, 142 20 Praha 4, Czech Republic.
2: Department of Biochemistry, Faculty of Science, Charles University Prague, Hlavova 8, 128 40 Praha, Czech Republic.
3: Division of Structural Biology, The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, England.
4: Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, v.v.i., Heyrovského nám. 2, 162 06 Praha 6, Czech Republic.

Articles cited by this

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res (1994) 392.47

Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features. Biopolymers (1983) 99.69

Features and development of Coot. Acta Crystallogr D Biol Crystallogr (2010) 89.46

Overview of the CCP4 suite and current developments. Acta Crystallogr D Biol Crystallogr (2011) 67.55

MolProbity: all-atom structure validation for macromolecular crystallography. Acta Crystallogr D Biol Crystallogr (2009) 53.36

Inference of macromolecular assemblies from crystalline state. J Mol Biol (2007) 44.95

Electrostatics of nanosystems: application to microtubules and the ribosome. Proc Natl Acad Sci U S A (2001) 42.14

REFMAC5 for the refinement of macromolecular crystal structures. Acta Crystallogr D Biol Crystallogr (2011) 39.32

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega. Mol Syst Biol (2011) 28.61

Molecular replacement with MOLREP. Acta Crystallogr D Biol Crystallogr (2009) 26.26

Improved R-factors for diffraction data analysis in macromolecular crystallography. Nat Struct Biol (1997) 25.74

iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM. Acta Crystallogr D Biol Crystallogr (2011) 18.13

Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol (1997) 11.14

Functions of natural killer cells. Nat Immunol (2008) 9.88

BALBES: a molecular-replacement pipeline. Acta Crystallogr D Biol Crystallogr (2007) 9.29

How good are my data and what is the resolution? Acta Crystallogr D Biol Crystallogr (2013) 8.98

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information. Nucleic Acids Res (2014) 8.86

Innate or adaptive immunity? The example of natural killer cells. Science (2011) 8.68

ESPript/ENDscript: Extracting and rendering sequence and 3D information from atomic structures of proteins. Nucleic Acids Res (2003) 8.66

Very fast empirical prediction and rationalization of protein pKa values. Proteins (2005) 8.61

Up on the tightrope: natural killer cell activation and inhibition. Nat Immunol (2008) 7.88

Human natural killer cells. Blood (2008) 7.37

Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2006) 7.29

PDB2PQR: expanding and upgrading automated preparation of biomolecular structures for molecular simulations. Nucleic Acids Res (2007) 7.07

High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells. Nucleic Acids Res (2002) 6.64

Structure and function in rhodopsin: high-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line. Proc Natl Acad Sci U S A (2002) 5.91

On the analysis of protein self-association by sedimentation velocity analytical ultracentrifugation. Anal Biochem (2003) 5.01

The C-type lectin-like domain superfamily. FEBS J (2005) 4.22

Immune functions encoded by the natural killer gene complex. Nat Rev Immunol (2003) 3.21

Prediction of hydrodynamic and other solution properties of rigid proteins from atomic- and residue-level models. Biophys J (2011) 2.79

CAVER 3.0: a tool for the analysis of transport pathways in dynamic protein structures. PLoS Comput Biol (2012) 2.64

Facilities for macromolecular crystallography at the Helmholtz-Zentrum Berlin. J Synchrotron Radiat (2012) 2.43

Cutting edge: lectin-like transcript-1 is a ligand for the inhibitory human NKR-P1A receptor. J Immunol (2005) 2.15

Cutting edge: lectin-like transcript 1 is a ligand for the CD161 receptor. J Immunol (2005) 1.97

Cytomegalovirus evasion of innate immunity by subversion of the NKR-P1B:Clr-b missing-self axis. Immunity (2007) 1.89

Functional consequences of interactions between human NKR-P1A and its ligand LLT1 expressed on activated dendritic cells and B cells. J Immunol (2008) 1.45

Induction of lectin-like transcript 1 (LLT1) protein cell surface expression by pathogens and interferon-γ contributes to modulate immune responses. J Biol Chem (2011) 1.28

Chemotherapy-induced genotoxic stress promotes sensitivity to natural killer cell cytotoxicity by enabling missing-self recognition. Cancer Res (2010) 1.11

The heterodimeric assembly of the CD94-NKG2 receptor family and implications for human leukocyte antigen-E recognition. Immunity (2007) 1.08

Crystal structure of human CD69: a C-type lectin-like activation marker of hematopoietic cells. Biochemistry (2000) 1.06

Two major groups of rat NKR-P1 receptors can be distinguished based on chromosomal localization, phylogenetic analysis and Clr ligand binding. Eur J Immunol (2009) 1.05

Crystal structure of the C-type lectin-like domain from the human hematopoietic cell receptor CD69. J Biol Chem (2000) 1.05

Deglycosylation of proteins for crystallization using recombinant fusion protein glycosidases. Protein Sci (1996) 1.04

The expression and function of the NKRP1 receptor family in C57BL/6 mice. J Immunol (2009) 1.03

Space-group and origin ambiguity in macromolecular structures with pseudo-symmetry and its treatment with the program Zanuda. Acta Crystallogr D Biol Crystallogr (2014) 1.02

Characterization of alternatively spliced transcript variants of CLEC2D gene. J Biol Chem (2010) 1.02

Evaluating the solution from MrBUMP and BALBES. Acta Crystallogr D Biol Crystallogr (2011) 1.02

Malignant glioma cells counteract antitumor immune responses through expression of lectin-like transcript-1. Cancer Res (2007) 0.99

Modulation of NK cell function by genetically coupled C-type lectin-like receptor/ligand pairs encoded in the human natural killer gene complex. Front Immunol (2013) 0.91

Molecular basis for LLT1 protein recognition by human CD161 protein (NKRP1A/KLRB1). J Biol Chem (2011) 0.90

Respiratory syncytial virus infection, TLR3 ligands, and proinflammatory cytokines induce CD161 ligand LLT1 expression on the respiratory epithelium. J Virol (2013) 0.86

Molecular architecture of mouse activating NKR-P1 receptors. J Struct Biol (2011) 0.85

Poxvirus infection-associated downregulation of C-type lectin-related-b prevents NK cell inhibition by NK receptor protein-1B. J Immunol (2012) 0.84

Soluble recombinant CD69 receptors optimized to have an exceptional physical and chemical stability display prolonged circulation and remain intact in the blood of mice. FEBS J (2008) 0.82

The high-resolution structure of the extracellular domain of human CD69 using a novel polymer. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.81

Structural analysis of natural killer cell receptor protein 1 (NKR-P1) extracellular domains suggests a conserved long loop region involved in ligand specificity. J Mol Model (2010) 0.81

Structure of NKp65 bound to its keratinocyte ligand reveals basis for genetically linked recognition in natural killer gene complex. Proc Natl Acad Sci U S A (2013) 0.80

Mouse Clr-g, a ligand for NK cell activation receptor NKR-P1F: crystal structure and biophysical properties. J Immunol (2012) 0.79

Re-evaluation of the involvement of NK cells and C-type lectin-like NK receptors in modulation of immune responses by multivalent GlcNAc-terminated oligosaccharides. Immunol Lett (2013) 0.78

Structure of the H107R variant of the extracellular domain of mouse NKR-P1A at 2.3 Å resolution. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.76

Expression and purification of soluble and stable ectodomain of natural killer cell receptor LLT1 through high-density transfection of suspension adapted HEK293S GnTI(-) cells. Protein Expr Purif (2015) 0.76