Published in Genes Dev on March 15, 2005
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature (2011) 13.30
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SWI/SNF mediates polycomb eviction and epigenetic reprogramming of the INK4b-ARF-INK4a locus. Mol Cell Biol (2008) 2.14
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Genetic ablation of Cyclin D1 abrogates genesis of rhabdoid tumors resulting from Ini1 loss. Proc Natl Acad Sci U S A (2005) 1.48
Loss of the epigenetic tumor suppressor SNF5 leads to cancer without genomic instability. Mol Cell Biol (2008) 1.36
Increased DNA damage sensitivity and apoptosis in cells lacking the Snf5/Ini1 subunit of the SWI/SNF chromatin remodeling complex. Mol Cell Biol (2006) 1.30
The transcriptional coactivator SAYP is a trithorax group signature subunit of the PBAP chromatin remodeling complex. Mol Cell Biol (2008) 1.23
Human SNF5/INI1, a component of the human SWI/SNF chromatin remodeling complex, promotes nucleotide excision repair by influencing ATM recruitment and downstream H2AX phosphorylation. Mol Cell Biol (2009) 1.10
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Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasms. Acta Neuropathol (2011) 1.04
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Stable knockdown of PASG enhances DNA demethylation but does not accelerate cellular senescence in TIG-7 human fibroblasts. Epigenetics (2008) 0.85
SNF5, a core component of the SWI/SNF complex, is necessary for p53 expression and cell survival, in part through eIF4E. Oncogene (2010) 0.82
The chromatin remodelling component SMARCB1/INI1 influences the metastatic behavior of colorectal cancer through a gene signature mapping to chromosome 22. J Transl Med (2013) 0.81
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Towards understanding the epigenetics of transcription by chromatin structure and the nuclear matrix. Gene Ther Mol Biol (2005) 0.79
Successful salvage and long-term survival after recurrent malignant rhabdoid tumor. Sarcoma (2007) 0.75
MYC interaction with the tumor suppressive SWI/SNF complex member INI1 regulates transcription and cellular transformation. Cell Cycle (2016) 0.75
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Oncogenic roles of SMARCB1/INI1 and its deficient tumors. Cancer Sci (2017) 0.75
Atypical ossifying fibromyxoid tumor unusually located in the mediastinum: report of a case showing mosaic loss of INI-1 expression. Int J Clin Exp Pathol (2015) 0.75
Mutational dichotomy in desmoplastic malignant melanoma corroborated by multigene panel analysis. Mod Pathol (2015) 0.75
RNA-based analysis of two SMARCB1 mutations associated with familial schwannomatosis with meningiomas. Neurogenetics (2012) 0.75
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Mutations in the APC tumour suppressor gene cause chromosomal instability. Nat Cell Biol (2001) 4.90
From polyploidy to aneuploidy, genome instability and cancer. Nat Rev Mol Cell Biol (2004) 4.72
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Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control. Nature (2004) 4.41
Germ-line and acquired mutations of INI1 in atypical teratoid and rhabdoid tumors. Cancer Res (1999) 4.26
The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression. EMBO Rep (2000) 3.30
Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice. Proc Natl Acad Sci U S A (2000) 2.91
Composition and functional specificity of SWI2/SNF2 class chromatin remodeling complexes. Biochim Biophys Acta (2004) 2.90
Disruption of Ini1 leads to peri-implantation lethality and tumorigenesis in mice. Mol Cell Biol (2001) 2.76
A revised picture of the E2F transcriptional network and RB function. Curr Opin Cell Biol (2002) 2.73
Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5. Cancer Cell (2002) 2.51
Constitutional mutations of the hSNF5/INI1 gene predispose to a variety of cancers. Am J Hum Genet (1999) 2.35
Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5. Mol Cell Biol (2002) 2.15
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Spectrum of hSNF5/INI1 somatic mutations in human cancer and genotype-phenotype correlations. Hum Mol Genet (1999) 1.96
The ctf13-30/CTF13 genomic haploinsufficiency modifier screen identifies the yeast chromatin remodeling complex RSC, which is required for the establishment of sister chromatid cohesion. Mol Cell Biol (2004) 1.87
The RSC nucleosome-remodeling complex is required for Cohesin's association with chromosome arms. Mol Cell (2004) 1.87
Re-expression of hSNF5/INI1/BAF47 in pediatric tumor cells leads to G1 arrest associated with induction of p16ink4a and activation of RB. Oncogene (2002) 1.81
Familial posterior fossa brain tumors of infancy secondary to germline mutation of the hSNF5 gene. Am J Hum Genet (2000) 1.80
P16INK4a is required for hSNF5 chromatin remodeler-induced cellular senescence in malignant rhabdoid tumor cells. J Biol Chem (2003) 1.67
Germ line transmission of the Cdk4(R24C) mutation facilitates tumorigenesis and escape from cellular senescence. Mol Cell Biol (2002) 1.58
A key role of the hSNF5/INI1 tumour suppressor in the control of the G1-S transition of the cell cycle. Oncogene (2002) 1.50
Loss of the INI1 tumor suppressor does not impair the expression of multiple BRG1-dependent genes or the assembly of SWI/SNF enzymes. Oncogene (2004) 1.22
Frequent deletion of hSNF5/INI1, a component of the SWI/SNF complex, in chronic myeloid leukemia. Cancer Res (1999) 1.10
Chromatin remodeling factor encoded by ini1 induces G1 arrest and apoptosis in ini1-deficient cells. Oncogene (2002) 0.99
Premature chromosome condensation revisited: a novel chemical approach permits efficient cytogenetic analysis of cancers. Genes Chromosomes Cancer (2003) 0.89
Chromosomal imbalances detected by comparative genomic hybridisation in atypical teratoid/rhabdoid tumours. Childs Nerv Syst (2004) 0.84
Differentially painting human chromosome arms with combined binary ratio-labeling fluorescence in situ hybridization. Genome Res (2000) 0.84
Novel germ-line deletion of SNF5/INI1/SMARCB1 gene in neonate presenting with congenital malignant rhabdoid tumor of kidney and brain primitive neuroectodermal tumor. Genes Chromosomes Cancer (2004) 0.83
Association between DNA content and tumor suppressor gene expression and aggressiveness of atypical teratoid/rhabdoid tumors. Childs Nerv Syst (2002) 0.82
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi. Nature (2008) 8.42
Composition and functional specificity of SWI2/SNF2 class chromatin remodeling complexes. Biochim Biophys Acta (2004) 2.90
Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway. Nat Cell Biol (2006) 2.58
In situ genotyping individual DNA molecules by target-primed rolling-circle amplification of padlock probes. Nat Methods (2004) 2.40
Metabolic labeling of C. elegans and D. melanogaster for quantitative proteomics. Nat Biotechnol (2003) 2.37
dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing. Genes Dev (2008) 2.29
GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7. Mol Cell (2005) 2.21
Differential targeting of two distinct SWI/SNF-related Drosophila chromatin-remodeling complexes. Mol Cell Biol (2004) 2.18
SWI/SNF mediates polycomb eviction and epigenetic reprogramming of the INK4b-ARF-INK4a locus. Mol Cell Biol (2008) 2.14
Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4. Genes Dev (2012) 2.04
Mitochondrial diabetes: molecular mechanisms and clinical presentation. Diabetes (2004) 1.95
A novel t(6;14)(q25-q27;q32) in acute myelocytic leukemia involves the BCL11B gene. Cancer Genet Cytogenet (2004) 1.77
The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter. J Biol Chem (2006) 1.77
A minority of foci or pan-nuclear apoptotic staining of gammaH2AX in the S phase after UV damage contain DNA double-strand breaks. Proc Natl Acad Sci U S A (2010) 1.77
The role of miR-18b in MDM2-p53 pathway signaling and melanoma progression. J Natl Cancer Inst (2013) 1.76
Pleiohomeotic can link polycomb to DNA and mediate transcriptional repression. Mol Cell Biol (2002) 1.74
Histone chaperones ASF1 and NAP1 differentially modulate removal of active histone marks by LID-RPD3 complexes during NOTCH silencing. Mol Cell (2009) 1.70
P16INK4a is required for hSNF5 chromatin remodeler-induced cellular senescence in malignant rhabdoid tumor cells. J Biol Chem (2003) 1.67
Functional differentiation of SWI/SNF remodelers in transcription and cell cycle control. Mol Cell Biol (2006) 1.65
miRNA-205 suppresses melanoma cell proliferation and induces senescence via regulation of E2F1 protein. J Biol Chem (2011) 1.63
Architecture of a polycomb nucleoprotein complex. Mol Cell (2006) 1.55
Synergistic recognition of an epigenetic DNA element by Pleiohomeotic and a Polycomb core complex. Genes Dev (2005) 1.52
GAGA can mediate enhancer function in trans by linking two separate DNA molecules. EMBO J (2002) 1.40
Real-time monitoring of rolling-circle amplification using a modified molecular beacon design. Nucleic Acids Res (2002) 1.39
Human cytomegalovirus US28 found in glioblastoma promotes an invasive and angiogenic phenotype. Cancer Res (2011) 1.36
The PHD type zinc finger is an integral part of the CBP acetyltransferase domain. Mol Cell Biol (2002) 1.36
DNA looping induced by a transcriptional enhancer in vivo. Nucleic Acids Res (2005) 1.32
The transcriptional coactivator SAYP is a trithorax group signature subunit of the PBAP chromatin remodeling complex. Mol Cell Biol (2008) 1.23
Quantitative assessment of a novel flow-through porous microarray for the rapid analysis of gene expression profiles. Nucleic Acids Res (2004) 1.22
Remodelers organize cellular chromatin by counteracting intrinsic histone-DNA sequence preferences in a class-specific manner. Mol Cell Biol (2011) 1.19
GAGA facilitates binding of Pleiohomeotic to a chromatinized Polycomb response element. Nucleic Acids Res (2003) 1.15
Microcephaly with simplified gyration, epilepsy, and infantile diabetes linked to inappropriate apoptosis of neural progenitors. Am J Hum Genet (2011) 1.12
Array-based comparative genomic hybridization analysis reveals recurrent chromosomal alterations and prognostic parameters in primary cutaneous large B-cell lymphoma. J Clin Oncol (2005) 1.12
Gene-specific targeting of the histone chaperone asf1 to mediate silencing. Dev Cell (2007) 1.10
Identification of RUNX1/AML1 as a classical tumor suppressor gene. Oncogene (2003) 1.08
EZH2-dependent chromatin looping controls INK4a and INK4b, but not ARF, during human progenitor cell differentiation and cellular senescence. Epigenetics Chromatin (2009) 1.05
Cytomegalovirus pp71 protein is expressed in human glioblastoma and promotes pro-angiogenic signaling by activation of stem cell factor. PLoS One (2013) 1.04
Two de novo mutations in the Na,K-ATPase gene ATP1A2 associated with pure familial hemiplegic migraine. Eur J Hum Genet (2006) 1.02
Metabolic enzyme IMPDH is also a transcription factor regulated by cellular state. Mol Cell (2012) 1.01
A multiplexed and miniaturized serological tuberculosis assay identifies antigens that discriminate maximally between TB and non-TB sera. J Immunol Methods (2005) 0.97
Drosophila transcription factor Tramtrack69 binds MEP1 to recruit the chromatin remodeler NuRD. Mol Cell Biol (2010) 0.97
Connexin 26 mutations in cases of sensorineural deafness in eastern Austria. Eur J Hum Genet (2002) 0.96
Distinct nuclear gene expression profiles in cells with mtDNA depletion and homoplasmic A3243G mutation. Mutat Res (2005) 0.95
A 10-Mb paracentric inversion of chromosome arm 2p inactivates MSH2 and is responsible for hereditary nonpolyposis colorectal cancer in a North-American kindred. Genes Chromosomes Cancer (2002) 0.95
In vivo stable isotope labeling of fruit flies reveals post-transcriptional regulation in the maternal-to-zygotic transition. Mol Cell Proteomics (2009) 0.94
Biosynthetic enzyme GMP synthetase cooperates with ubiquitin-specific protease 7 in transcriptional regulation of ecdysteroid target genes. Mol Cell Biol (2009) 0.92
Hydroxyurea responsiveness in β-thalassemic patients is determined by the stress response adaptation of erythroid progenitors and their differentiation propensity. Haematologica (2012) 0.91
HCMV glycoprotein B is expressed in primary glioblastomas and enhances growth and invasiveness via PDGFR-alpha activation. Oncotarget (2014) 0.91
Deubiquitylating enzyme UBP64 controls cell fate through stabilization of the transcriptional repressor tramtrack. Mol Cell Biol (2007) 0.91
Immuno-depletion and purification strategies to study chromatin-remodeling factors in vitro. Methods Enzymol (2004) 0.91
Phosphorylation-mediated control of histone chaperone ASF1 levels by Tousled-like kinases. PLoS One (2009) 0.89
Gene expression control by protein deubiquitinases. Curr Opin Genet Dev (2011) 0.88
Transcription-independent function of Polycomb group protein PSC in cell cycle control. Science (2012) 0.88
Characterization of the extended Myb-like DNA-binding domain of trithorax group protein Zeste. J Biol Chem (2002) 0.87
APC inactivation associates with abnormal mitosis completion and concomitant BUB1B/MAD2L1 up-regulation. Gastroenterology (2007) 0.87
Positioning of cervical carcinoma and Burkitt lymphoma translocation breakpoints with respect to the human papillomavirus integration cluster in FRA8C at 8q24.13. Cancer Genet Cytogenet (2004) 0.86
PCC and COBRA-FISH a new tool to characterize primary cervical carcinomas: to assess hall-marks and stage specificity. Cancer Lett (2009) 0.85
Conceptual developments in the causes of Cockayne syndrome. Mech Ageing Dev (2013) 0.85
Differential expression of tapasin and immunoproteasome subunits in adenovirus type 5- versus type 12-transformed cells. J Biol Chem (2002) 0.84
Localization and regulation of the growth hormone receptor and growth hormone-binding protein in the rat growth plate. J Bone Miner Res (2002) 0.84
Subunits of the histone chaperone CAF1 also mediate assembly of protamine-based chromatin. Cell Rep (2013) 0.83
Pleckstrin homology domain-interacting protein (PHIP) as a marker and mediator of melanoma metastasis. Proc Natl Acad Sci U S A (2012) 0.82
Histone chaperone NAP1 mediates sister chromatid resolution by counteracting protein phosphatase 2A. PLoS Genet (2013) 0.82
Molecular biology. A higher order of silence. Science (2004) 0.80
The A3243G tRNALeu(UUR) mutation induces mitochondrial dysfunction and variable disease expression without dominant negative acting translational defects in complex IV subunits at UUR codons. Hum Mol Genet (2007) 0.80
New insights in the molecular pathogenesis of the maternally inherited diabetes and deafness syndrome. Endocrinol Metab Clin North Am (2006) 0.79
Metastatic melanoma with striking adenocarcinomatous differentiation illustrating phenotypic plasticity in melanoma. Am J Surg Pathol (2011) 0.77
Multiple supernumerary ring chromosomes of different origin in a patient: a clinical report and review of the literature. Am J Med Genet A (2003) 0.77
Multicolor Fiber FISH. Methods Mol Biol (2002) 0.77
Single-cell A3243G mitochondrial DNA mutation load assays for segregation analysis. J Histochem Cytochem (2007) 0.77
Simultaneous mapping of human papillomavirus integration sites and molecular karyotyping in short-term cultures of cervical carcinomas by using 49-color combined binary ratio labeling fluorescence in situ hybridization. Cancer Genet Cytogenet (2002) 0.76
Comprehensive analysis of human subtelomeres with combined binary ratio labelling fluorescence in situ hybridisation. Eur J Hum Genet (2003) 0.75
Complex biallelic IGH rearrangements in IgM-expressing Z-138 cell line: Involvement of downstream immunoglobulin class switch recombination. Genes Chromosomes Cancer (2005) 0.75
Correction: Human mutations in integrator complex subunits link transcriptome integrity to brain development. PLoS Genet (2017) 0.75
Molecular cytogenetic characterization by combined COBRA-FISH and fiber-FISH: application to PER.C6 cells. Biotechniques (2004) 0.75
Fluorescence properties, thermal duplex stability, and kinetics of formation of cyanin platinum DNAs. Anal Biochem (2003) 0.75
Abnormal kinetics of induction of UV-stimulated recombination in human DNA repair disorders. DNA Repair (Amst) (2003) 0.75