PubRank

R E Hussey

Author PubWeight™ 101.00‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex. J Exp Med 1983 9.23
2 An alternative pathway of T-cell activation: a functional role for the 50 kd T11 sheep erythrocyte receptor protein. Cell 1984 7.56
3 Evidence for the T3-associated 90K heterodimer as the T-cell antigen receptor. Nature 1983 4.96
4 Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex. Cell 1982 4.86
5 Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway. Proc Natl Acad Sci U S A 1984 4.78
6 Antigen-like effects of monoclonal antibodies directed at receptors on human T cell clones. J Exp Med 1983 4.10
7 A monoclonal antibody blocking human T cell function. Eur J Immunol 1980 3.33
8 The crystal structure of a T cell receptor in complex with peptide and MHC class II. Science 1999 3.23
9 The human T cell receptor: appearance in ontogeny and biochemical relationship of alpha and beta subunits on IL-2 dependent clones and T cell tumors. Cell 1983 3.07
10 Comparison of T3-associated 49- and 43-kilodalton cell surface molecules on individual human T-cell clones: evidence for peptide variability in T-cell receptor structures. Proc Natl Acad Sci U S A 1983 2.93
11 Heterogeneity of human T4+ inducer T cells defined by a monoclonal antibody that delineates two functional subpopulations. J Immunol 1982 2.60
12 Substitution of murine for human CD4 residues identifies amino acids critical for HIV-gp120 binding. Nature 1988 2.53
13 Surface structures involved in target recognition by human cytotoxic T lymphocytes. Science 1982 2.52
14 Antibody directed at a surface structure inhibits cytolytic but not suppressor function of human T lymphocytes. Nature 1981 2.39
15 Activation of human thymocytes via the 50KD T11 sheep erythrocyte binding protein induces the expression of interleukin 2 receptors on both T3+ and T3- populations. J Immunol 1985 2.37
16 Identification of the receptor for antigen and major histocompatibility complex on human inducer T lymphocytes. Science 1983 2.21
17 Cellular origin of interleukin 2 (IL 2) in man: evidence for stimulus-restricted IL 2 production by T4+ and T8+ T lymphocytes. J Immunol 1982 1.87
18 Ta1, a novel 105 KD human T cell activation antigen defined by a monoclonal antibody. J Immunol 1984 1.84
19 Analysis of T-cell receptor gene rearrangement and expression in human natural killer clones. Science 1985 1.83
20 Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody. EMBO J 1998 1.74
21 Structural basis of CD8 coreceptor function revealed by crystallographic analysis of a murine CD8alphaalpha ectodomain fragment in complex with H-2Kb. Immunity 1998 1.51
22 Molecular cloning and expression of T11 cDNAs reveal a receptor-like structure on human T lymphocytes. Proc Natl Acad Sci U S A 1987 1.49
23 Reconstitution after transplantation with T-lymphocyte-depleted HLA haplotype-mismatched bone marrow for severe combined immunodeficiency. Proc Natl Acad Sci U S A 1982 1.44
24 Molecular analysis of T cell receptor (Ti) variable region (V) gene expression. Evidence that a single Ti beta V gene family can be used in formation of V domains on phenotypically and functionally diverse T cell populations. J Exp Med 1985 1.34
25 Expression, purification, and characterization of recombinant HIV gp140. The gp41 ectodomain of HIV or simian immunodeficiency virus is sufficient to maintain the retroviral envelope glycoprotein as a trimer. J Biol Chem 2001 1.34
26 A soluble, single-chain T-cell receptor fragment endowed with antigen-combining properties. Proc Natl Acad Sci U S A 1991 1.28
27 Expression, purification, and characterization of gp160e, the soluble, trimeric ectodomain of the simian immunodeficiency virus envelope glycoprotein, gp160. J Biol Chem 2000 1.26
28 Absence of expression of Ia antigen on human cytotoxic T cells. Immunogenetics 1980 1.20
29 A rapid method for separating functionally intact human T lymphocytes with monoclonal antibodies. Clin Immunol Immunopathol 1981 1.19
30 Human cytotoxic T cell clones directed at autologous virus-transformed targets: further evidence for linkage of genetic restriction to T4 and T8 surface glycoproteins. J Immunol 1983 1.18
31 Binding site for human immunodeficiency virus coat protein gp120 is located in the NH2-terminal region of T4 (CD4) and requires the intact variable-region-like domain. Proc Natl Acad Sci U S A 1988 1.17
32 The stoichiometry of trimeric SIV glycoprotein interaction with CD4 differs from that of anti-envelope antibody Fab fragments. J Biol Chem 2001 1.16
33 Structural and binding analysis of a two domain extracellular CD2 molecule. J Exp Med 1989 1.14
34 Immunoregulatory human T lymphocytes triggered as a consequence of viral infection: clonal analysis of helper, suppressor inducer and suppressor effector cell populations. J Immunol 1983 1.14
35 Identification of a common docking topology with substantial variation among different TCR-peptide-MHC complexes. Curr Biol 1998 1.11
36 T3-Ti receptor triggering of T8+ suppressor T cells leads to unresponsiveness to interleukin-2. Nature 1984 1.09
37 Delineation of a T-cell activation motif required for binding of protein tyrosine kinases containing tandem SH2 domains. Proc Natl Acad Sci U S A 1994 1.07
38 Expression, purification, and functional analysis of murine ectodomain fragments of CD8alphaalpha and CD8alphabeta dimers. J Biol Chem 1999 1.02
39 CD3 eta and CD3 zeta are alternatively spliced products of a common genetic locus and are transcriptionally and/or post-transcriptionally regulated during T-cell development. Proc Natl Acad Sci U S A 1991 1.02
40 Crystallization of a deglycosylated T cell receptor (TCR) complexed with an anti-TCR Fab fragment. J Biol Chem 1996 0.98
41 A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion. EMBO J 1998 0.98
42 Double-positive T cell receptor(high) thymocytes are resistant to peptide/major histocompatibility complex ligand-induced negative selection. Eur J Immunol 1997 0.96
43 Adhesion domain of human T11 (CD2) is encoded by a single exon. Proc Natl Acad Sci U S A 1988 0.87
44 A critical role for p59(fyn) in CD2-based signal transduction. Eur J Immunol 2000 0.86
45 Multiple class I and class II major histocompatibility complex allospecificities are generated with T cell receptor variable (V) domains created by a single Ti beta V gene family. J Exp Med 1985 0.85
46 The T 11 (CD 2) cDNA encodes a transmembrane protein which expresses T 11(1), T 11(2) and T 11(3) epitopes but which does not independently mediate calcium influx: analysis by gene transfer in a baculovirus system. Eur J Immunol 1988 0.82
47 Targeted disruption within the CD3 zeta/eta/phi/Oct-1 locus in mouse. EMBO J 1994 0.81
48 Human CD4 residue Phe 43 is critical for repertoire development and maturation of MHC class II restricted CD4 single-positive T lineage cells in vivo. Eur J Immunol 2000 0.78
49 A simple perfusion chamber for studying neurotransmitter release from cells maintained in monolayer culture. J Neurosci Methods 1981 0.75
50 T-cell-receptor isoforms. Int J Cancer Suppl 1992 0.75