Published in Anesthesiology on May 01, 2015
Noble path to oblivion: molecular and neurophysiological mechanisms of xenon. Anesthesiology (2015) 0.75
The endogenous cannabinoid system controls extinction of aversive memories. Nature (2002) 7.19
Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates. PLoS One (2010) 6.38
Surgical site infection and the routine use of perioperative hyperoxia in a general surgical population: a randomized controlled trial. JAMA (2004) 5.44
Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa. Science (2010) 3.92
Quantification of the sixth DNA base hydroxymethylcytosine in the brain. Angew Chem Int Ed Engl (2010) 3.50
Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2. EMBO J (2003) 3.02
Emerging molecular mechanisms of general anesthetic action. Trends Pharmacol Sci (2005) 2.91
Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. Cell Stem Cell (2013) 2.74
Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders. Nat Rev Drug Discov (2010) 2.68
The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart. Proc Natl Acad Sci U S A (2003) 2.53
The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal stores. Pflugers Arch (2009) 2.35
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells. Nature (2012) 2.32
An extrasynaptic GABAA receptor mediates tonic inhibition in thalamic VB neurons. J Neurophysiol (2005) 2.22
Enhanced and delayed stress-induced alcohol drinking in mice lacking functional CRH1 receptors. Science (2002) 1.93
Contribution of the receptor guanylyl cyclase GC-D to chemosensory function in the olfactory epithelium. Proc Natl Acad Sci U S A (2007) 1.88
Brain-derived neurotrophic factor triggers transcription-dependent, late phase long-term potentiation in vivo. J Neurosci (2002) 1.80
Circuitry for associative plasticity in the amygdala involves endocannabinoid signaling. J Neurosci (2004) 1.70
Reduced anxiety, conditioned fear, and hippocampal long-term potentiation in transient receptor potential vanilloid type 1 receptor-deficient mice. J Neurosci (2007) 1.70
Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels. J Biol Chem (2003) 1.63
Xenon reduces N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated synaptic transmission in the amygdala. Anesthesiology (2008) 1.63
Characterization of two-pore channel 2 (TPCN2)-mediated Ca2+ currents in isolated lysosomes. J Biol Chem (2010) 1.62
Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects. Science (2009) 1.61
Monitoring depth of anesthesia utilizing a combination of electroencephalographic and standard measures. Anesthesiology (2014) 1.55
Targeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f). FASEB J (2008) 1.54
Cannabinoid receptor type 1 located on presynaptic terminals of principal neurons in the forebrain controls glutamatergic synaptic transmission. J Neurosci (2006) 1.48
Restoration of cone vision in the CNGA3-/- mouse model of congenital complete lack of cone photoreceptor function. Mol Ther (2010) 1.46
Taurine is a potent activator of extrasynaptic GABA(A) receptors in the thalamus. J Neurosci (2008) 1.45
An olfactory subsystem that detects carbon disulfide and mediates food-related social learning. Curr Biol (2010) 1.44
Activation of the cannabinoid receptor type 1 decreases glutamatergic and GABAergic synaptic transmission in the lateral amygdala of the mouse. Learn Mem (2003) 1.42
Impaired channel targeting and retinal degeneration in mice lacking the cyclic nucleotide-gated channel subunit CNGB1. J Neurosci (2005) 1.40
Impaired opsin targeting and cone photoreceptor migration in the retina of mice lacking the cyclic nucleotide-gated channel CNGA3. Invest Ophthalmol Vis Sci (2005) 1.38
Switching off calcium-dependent inactivation in L-type calcium channels by an autoinhibitory domain. Proc Natl Acad Sci U S A (2006) 1.37
The effect of the alpha 2-agonist dexmedetomidine and the N-methyl-D-aspartate antagonist S(+)-ketamine on the expression of apoptosis-regulating proteins after incomplete cerebral ischemia and reperfusion in rats. Anesth Analg (2003) 1.34
A novel mechanism of modulation of hyperpolarization-activated cyclic nucleotide-gated channels by Src kinase. J Biol Chem (2005) 1.32
High risk of cognitive and functional decline after postoperative delirium. A three-year prospective study. Dement Geriatr Cogn Disord (2008) 1.30
Exploring HCN channels as novel drug targets. Nat Rev Drug Discov (2011) 1.28
Synaptic plasticity in CNGA3(-/-) mice: cone bipolar cells react on the missing cone input and form ectopic synapses with rods. J Neurosci (2006) 1.24
The murine HCN3 gene encodes a hyperpolarization-activated cation channel with slow kinetics and unique response to cyclic nucleotides. J Biol Chem (2005) 1.21
Morphological characterization of the retina of the CNGA3(-/-)Rho(-/-) mutant mouse lacking functional cones and rods. Invest Ophthalmol Vis Sci (2004) 1.21
Functional characterization of the L-type Ca2+ channel Cav1.4alpha1 from mouse retina. Invest Ophthalmol Vis Sci (2004) 1.21
Dominant-negative suppression of HCN channels markedly reduces the native pacemaker current I(f) and undermines spontaneous beating of neonatal cardiomyocytes. Circulation (2003) 1.20
Loss of CNGB1 protein leads to olfactory dysfunction and subciliary cyclic nucleotide-gated channel trapping. J Biol Chem (2006) 1.20
Memantine improves cognition and reduces Alzheimer's-like neuropathology in transgenic mice. Am J Pathol (2009) 1.19
Dual regulation of translation initiation and peptide chain elongation during BDNF-induced LTP in vivo: evidence for compartment-specific translation control. J Neurochem (2006) 1.18
Isoflurane anaesthesia reversibly improves cognitive function and long-term potentiation (LTP) via an up-regulation in NMDA receptor 2B subunit expression. Neuropharmacology (2008) 1.16
Prolongation of hippocampal miniature inhibitory postsynaptic currents in mice lacking the GABA(A) receptor alpha1 subunit. J Neurophysiol (2002) 1.14
Isoflurane is a potent modulator of extrasynaptic GABA(A) receptors in the thalamus. J Pharmacol Exp Ther (2007) 1.13
A key role for cyclic nucleotide gated (CNG) channels in cGMP-related retinitis pigmentosa. Hum Mol Genet (2010) 1.13
Melatonin and anesthesia: a clinical perspective. J Pineal Res (2007) 1.13
Role of TRPML and two-pore channels in endolysosomal cation homeostasis. J Pharmacol Exp Ther (2012) 1.13
HCN3 contributes to the ventricular action potential waveform in the murine heart. Circ Res (2011) 1.11
Grating acuity at different luminances in wild-type mice and in mice lacking rod or cone function. Invest Ophthalmol Vis Sci (2005) 1.08
Vision tests in the mouse: Functional phenotyping with electroretinography. Front Biosci (Landmark Ed) (2009) 1.08
Chronic social stress during adolescence induces cognitive impairment in aged mice. Hippocampus (2010) 1.07
Gene therapy restores vision and delays degeneration in the CNGB1(-/-) mouse model of retinitis pigmentosa. Hum Mol Genet (2012) 1.07
Propofol block of I(h) contributes to the suppression of neuronal excitability and rhythmic burst firing in thalamocortical neurons. Eur J Neurosci (2006) 1.06
Time delay of index calculation: analysis of cerebral state, bispectral, and narcotrend indices. Anesthesiology (2006) 1.05
International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels. Pharmacol Rev (2005) 1.04
Impairment of hyperpolarization-activated, cyclic nucleotide-gated channel function by the intravenous general anesthetic propofol. J Pharmacol Exp Ther (2005) 1.03
Isoflurane modulates glutamatergic and GABAergic neurotransmission in the amygdala. Eur J Neurosci (2004) 1.01
Contributions of GABAergic and glutamatergic mechanisms to isoflurane-induced suppression of thalamic somatosensory information transfer. Exp Brain Res (2006) 1.00
Forebrain CRF₁ modulates early-life stress-programmed cognitive deficits. J Neurosci (2011) 1.00
Antidepressants and antipsychotic drugs colocalize with 5-HT3 receptors in raft-like domains. J Neurosci (2005) 1.00
Endoplasmic reticulum stress-associated cone photoreceptor degeneration in cyclic nucleotide-gated channel deficiency. J Biol Chem (2012) 1.00
cGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: evidence of cGMP cytotoxicity independently of enhanced CNG channel function. J Neurosci (2013) 0.99
Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice. J Clin Invest (2009) 0.98
Influence of propofol on neuronal damage and apoptotic factors after incomplete cerebral ischemia and reperfusion in rats: a long-term observation. Anesthesiology (2004) 0.98
Rod and cone contributions to horizontal cell light responses in the mouse retina. J Neurosci (2008) 0.98
Effect of the alpha2-agonist dexmedetomidine on cerebral neurotransmitter concentrations during cerebral ischemia in rats. Anesthesiology (2002) 0.98
Dendritic HCN2 channels constrain glutamate-driven excitability in reticular thalamic neurons. J Neurosci (2007) 0.98
The modulation of synaptic GABA(A) receptors in the thalamus by eszopiclone and zolpidem. J Pharmacol Exp Ther (2008) 0.97
Complex regulation of voltage-dependent activation and inactivation properties of retinal voltage-gated Cav1.4 L-type Ca2+ channels by Ca2+-binding protein 4 (CaBP4). J Biol Chem (2012) 0.97
NF-E2 overexpression delays erythroid maturation and increases erythrocyte production. Br J Haematol (2009) 0.95
Propofol-block of SK channels in reticular thalamic neurons enhances GABAergic inhibition in relay neurons. J Neurophysiol (2004) 0.95
International Union of Pharmacology. XLII. Compendium of voltage-gated ion channels: cyclic nucleotide-modulated channels. Pharmacol Rev (2003) 0.95
Grueneberg ganglion neurons are finely tuned cold sensors. J Neurosci (2010) 0.95
Distribution and properties of functional postsynaptic kainate receptors on neocortical layer V pyramidal neurons. J Neurosci (2003) 0.94
Isoflurane reduces glutamatergic transmission in neurons in the spinal cord superficial dorsal horn: evidence for a presynaptic site of an analgesic action. Anesth Analg (2004) 0.94
Bispectral Index (BIS) may not predict awareness reaction to intubation in surgical patients. J Neurosurg Anesthesiol (2002) 0.93
Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits. PLoS One (2012) 0.92
Molecular basis for the different activation kinetics of the pacemaker channels HCN2 and HCN4. J Biol Chem (2003) 0.92
Cellular zinc levels are modulated by TRPML1-TMEM163 interaction. Traffic (2014) 0.92
The effect of hypothermia on the expression of the apoptosis-regulating protein Bax after incomplete cerebral ischemia and reperfusion in rats. J Neurosurg Anesthesiol (2003) 0.92
Anesthesia and postoperative cognitive dysfunction (POCD). Mini Rev Med Chem (2009) 0.92
Residual photosensitivity in mice lacking both rod opsin and cone photoreceptor cyclic nucleotide gated channel 3 alpha subunit. Vis Neurosci (2005) 0.91
Characterization of neurite outgrowth and ectopic synaptogenesis in response to photoreceptor dysfunction. Cell Mol Life Sci (2012) 0.91
Regulation of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel activity by cCMP. J Biol Chem (2012) 0.91
Chemo- and thermosensory responsiveness of Grueneberg ganglion neurons relies on cyclic guanosine monophosphate signaling elements. Neurosignals (2011) 0.91
Calmodulin is a functional regulator of Cav1.4 L-type Ca2+ channels. J Biol Chem (2009) 0.91
NAADP and the two-pore channel protein 1 participate in the acrosome reaction in mammalian spermatozoa. Mol Biol Cell (2014) 0.89
Gene therapy restores missing cone-mediated vision in the CNGA3-/- mouse model of achromatopsia. Adv Exp Med Biol (2012) 0.89
Sick sinus syndrome in HCN1-deficient mice. Circulation (2013) 0.89
The glutamic acid-rich protein is a gating inhibitor of cyclic nucleotide-gated channels. J Neurosci (2011) 0.89