Published in Immunity on April 07, 2015
NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth. Nat Immunol (2017) 2.69
Innate lymphoid cells in the initiation, regulation and resolution of inflammation. Nat Med (2015) 1.63
On-going Mechanical Damage from Mastication Drives Homeostatic Th17 Cell Responses at the Oral Barrier. Immunity (2017) 1.38
Unique and redundant functions of NKp46+ ILC3s in models of intestinal inflammation. J Exp Med (2015) 1.11
Antibiotic-Induced Changes in the Intestinal Microbiota and Disease. Trends Mol Med (2016) 0.94
Dancing with the Stars: How Choreographed Bacterial Interactions Dictate Nososymbiocity and Give Rise to Keystone Pathogens, Accessory Pathogens, and Pathobionts. Trends Microbiol (2016) 0.89
Increased Intestinal Microbial Diversity Following Fecal Microbiota Transplant for Active Crohn's Disease. Inflamm Bowel Dis (2016) 0.87
In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity. Nat Med (2015) 0.87
Novel perspectives on therapeutic modulation of the gut microbiota. Therap Adv Gastroenterol (2016) 0.86
The microbiota and chronic kidney diseases: a double-edged sword. Clin Transl Immunology (2016) 0.86
Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection. Nat Med (2016) 0.85
Microbiota and host immune responses: a love-hate relationship. Immunology (2015) 0.84
Monocyte-mediated defense against bacteria, fungi, and parasites. Semin Immunol (2016) 0.82
Inflammasomes and intestinal inflammation. Mucosal Immunol (2017) 0.81
Immune Cells and Inflammation in Diabetic Nephropathy. J Diabetes Res (2015) 0.81
Intestinal macrophages arising from CCR2(+) monocytes control pathogen infection by activating innate lymphoid cells. Nat Commun (2015) 0.80
IL-1 in Colon Inflammation, Colon Carcinogenesis and Invasiveness of Colon Cancer. Cancer Microenviron (2015) 0.80
Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome. J Exp Med (2017) 0.79
Commensal Bacteria-induced Interleukin 1β (IL-1β) Secreted by Macrophages Up-regulates Hepcidin Expression in Hepatocytes by Activating the Bone Morphogenetic Protein Signaling Pathway. J Biol Chem (2015) 0.78
The Pathogenic Potential of Proteus mirabilis is Enhanced by Other Uropathogens During Polymicrobial Urinary Tract Infection. Infect Immun (2016) 0.77
Proteus mirabilis fimbriae- and urease-dependent clusters assemble in an extracellular niche to initiate bladder stone formation. Proc Natl Acad Sci U S A (2016) 0.77
The regulation of host defences to infection by the microbiota. Immunology (2016) 0.77
Innate Sensing of the Gut Microbiota: Modulation of Inflammatory and Autoimmune Diseases. Front Immunol (2016) 0.77
Inflammatory Th1 and Th17 in the Intestine Are Each Driven by Functionally Specialized Dendritic Cells with Distinct Requirements for MyD88. Cell Rep (2016) 0.77
Structural robustness of the gut mucosal microbiota is associated with Crohn's disease remission after surgery. Gut (2015) 0.77
MALT1 inhibitors prevent the development of DSS-induced experimental colitis in mice via inhibiting NF-κB and NLRP3 inflammasome activation. Oncotarget (2016) 0.76
Proteus mirabilis: The Enemy Within. Immunity (2015) 0.75
Commensal Bacteria-Induced Inflammasome Activation in Mouse and Human Macrophages Is Dependent on Potassium Efflux but Does Not Require Phagocytosis or Bacterial Viability. PLoS One (2016) 0.75
The Goldilocks Conundrum: NLR Inflammasome Modulation of Gastrointestinal Inflammation during Inflammatory Bowel Disease. Crit Rev Immunol (2016) 0.75
C7 genotype of the donor may predict early bacterial infection after liver transplantation. Sci Rep (2016) 0.75
The mucosal immune system: master regulator of bidirectional gut-brain communications. Nat Rev Gastroenterol Hepatol (2017) 0.75
Canonical and Non-Canonical Activation of NLRP3 Inflammasome at the Crossroad between Immune Tolerance and Intestinal Inflammation. Front Immunol (2017) 0.75
Antigen Presentation in Transplantation. Trends Immunol (2016) 0.75
Epithelial Cell Inflammasomes in Intestinal Immunity and Inflammation. Front Immunol (2017) 0.75
Microbiome-mediated neutrophil recruitment via CXCR2 and protection from amebic colitis. PLoS Pathog (2017) 0.75
Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages. Oncoimmunology (2017) 0.75
The RAST Server: rapid annotations using subsystems technology. BMC Genomics (2008) 175.18
Velvet: algorithms for de novo short read assembly using de Bruijn graphs. Genome Res (2008) 151.16
Prokka: rapid prokaryotic genome annotation. Bioinformatics (2014) 32.73
Pattern recognition receptors and inflammation. Cell (2010) 21.05
The inflammasomes. Cell (2010) 19.37
Cryopyrin activates the inflammasome in response to toxins and ATP. Nature (2006) 18.74
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol (2008) 16.65
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature (2008) 11.39
Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat Immunol (2006) 11.06
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat Immunol (2006) 10.55
Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system. Cell (2007) 8.42
Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. Proc Natl Acad Sci U S A (2010) 5.59
Sensing and reacting to microbes through the inflammasomes. Nat Immunol (2012) 5.24
The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity (2010) 5.12
Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22. J Exp Med (2008) 4.95
Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis. Cell Host Microbe (2010) 4.54
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. J Exp Med (2010) 4.37
Role of the gut microbiota in immunity and inflammatory disease. Nat Rev Immunol (2013) 4.34
Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity. J Clin Invest (2005) 4.26
Deletion of TLR5 results in spontaneous colitis in mice. J Clin Invest (2007) 4.18
K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter. Immunity (2013) 3.96
Commensal Bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease. Cell Host Microbe (2011) 3.46
IL-1 beta -converting enzyme (caspase-1) in intestinal inflammation. Proc Natl Acad Sci U S A (2001) 3.21
Role of interleukin 1 in inflammatory bowel disease--enhanced production during active disease. Gut (1990) 3.18
Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells. Immunity (2012) 3.18
Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells. J Exp Med (2006) 3.12
Inflammatory monocytes facilitate adaptive CD4 T cell responses during respiratory fungal infection. Cell Host Microbe (2009) 2.81
Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury. J Clin Invest (2007) 2.55
Genetic and biochemical diversity of ureases of Proteus, Providencia, and Morganella species isolated from urinary tract infection. Infect Immun (1987) 2.52
The Nod2 sensor promotes intestinal pathogen eradication via the chemokine CCL2-dependent recruitment of inflammatory monocytes. Immunity (2011) 2.47
Complete genome sequence of uropathogenic Proteus mirabilis, a master of both adherence and motility. J Bacteriol (2008) 2.47
Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome. Gut (2010) 2.42
IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4(+) Th17 cells. J Exp Med (2012) 2.11
NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense. Nat Immunol (2012) 1.97
The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells. Immunity (2012) 1.97
Non-redundant properties of IL-1α and IL-1β during acute colon inflammation in mice. Gut (2013) 1.84
The innate immune receptor Nod1 protects the intestine from inflammation-induced tumorigenesis. Cancer Res (2008) 1.78
Dextran sodium sulfate-induced colitis in germ-free IQI/Jic mice. Exp Anim (2001) 1.58
Cytotoxic activity of the Proteus hemolysin HpmA. Infect Immun (1990) 1.57
Merging mythology and morphology: the multifaceted lifestyle of Proteus mirabilis. Nat Rev Microbiol (2012) 1.48
Intestinal macrophages: well educated exceptions from the rule. Trends Immunol (2013) 1.47
B cell-intrinsic MyD88 signaling prevents the lethal dissemination of commensal bacteria during colonic damage. Immunity (2012) 1.47
Colonic eosinophilic inflammation in experimental colitis is mediated by Ly6C(high) CCR2(+) inflammatory monocyte/macrophage-derived CCL11. J Immunol (2011) 1.33
The role of microflora in the development of intestinal inflammation: acute and chronic colitis induced by dextran sulfate in germ-free and conventionally reared immunocompetent and immunodeficient mice. Folia Microbiol (Praha) (2001) 1.23
Regulation of the immune system by the resident intestinal bacteria. Gastroenterology (2014) 1.19
Multicellular bacteria deploy the type VI secretion system to preemptively strike neighboring cells. PLoS Pathog (2013) 1.14
Nonpathogenic Escherichia coli strain Nissle1917 prevents murine acute and chronic colitis. Inflamm Bowel Dis (2005) 1.07
Protective and aggravating effects of Nlrp3 inflammasome activation in IBD models: influence of genetic and environmental factors. Dig Dis (2012) 1.01
Escherichia coli isolates from inflammatory bowel diseases patients survive in macrophages and activate NLRP3 inflammasome. Int J Med Microbiol (2014) 0.93
AIEC colonization and pathogenicity: influence of previous antibiotic treatment and preexisting inflammation. Inflamm Bowel Dis (2012) 0.84