Published in Nucleic Acids Res on April 20, 2015
Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature (1997) 44.55
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature (2002) 14.63
Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle- and developmentally regulated promoter. Cell (1999) 6.83
A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell (2006) 6.61
A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage. Cell (1995) 6.00
Rad6-dependent ubiquitination of histone H2B in yeast. Science (2000) 4.68
The recognition component of the N-end rule pathway. EMBO J (1990) 4.55
Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter. Mol Cell (2003) 4.49
Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes Dev (2001) 4.28
Global response of Saccharomyces cerevisiae to an alkylating agent. Proc Natl Acad Sci U S A (1999) 4.27
Regulatory networks revealed by transcriptional profiling of damaged Saccharomyces cerevisiae cells: Rpn4 links base excision repair with proteasomes. Mol Cell Biol (2000) 4.15
Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance. Microbiol Mol Biol Rev (2009) 3.62
Structure of the yeast nucleosome core particle reveals fundamental changes in internucleosome interactions. EMBO J (2001) 3.27
Recruitment of Mec1 and Ddc1 checkpoint proteins to double-strand breaks through distinct mechanisms. Science (2001) 3.13
Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities. J Biol Chem (1997) 3.11
Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell (2008) 3.09
A compiled and systematic reference map of nucleosome positions across the Saccharomyces cerevisiae genome. Genome Biol (2009) 2.58
Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9. Mol Cell Biol (2005) 2.48
The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1. J Biol Chem (2005) 2.27
Saccharomyces cerevisiae Rad9 acts as a Mec1 adaptor to allow Rad53 activation. Curr Biol (2005) 2.20
The highly conserved N-terminal domains of histones H3 and H4 are required for normal cell cycle progression. Mol Cell Biol (1991) 2.18
Prime, repair, restore: the active role of chromatin in the DNA damage response. Mol Cell (2012) 2.04
Probing nucleosome function: a highly versatile library of synthetic histone H3 and H4 mutants. Cell (2008) 1.99
Cloning a eukaryotic DNA glycosylase repair gene by the suppression of a DNA repair defect in Escherichia coli. Proc Natl Acad Sci U S A (1989) 1.97
Generation of a strong mutator phenotype in yeast by imbalanced base excision repair. Proc Natl Acad Sci U S A (1998) 1.82
Histone H3 and the histone acetyltransferase Hat1p contribute to DNA double-strand break repair. Mol Cell Biol (2002) 1.78
Nucleosome structure and repair of N-methylpurines in the GAL1-10 genes of Saccharomyces cerevisiae. J Biol Chem (2002) 1.53
The Rad53 signal transduction pathway: Replication fork stabilization, DNA repair, and adaptation. Exp Cell Res (2006) 1.52
Rad4-Rad23 interaction with SWI/SNF links ATP-dependent chromatin remodeling with nucleotide excision repair. Nat Struct Mol Biol (2006) 1.51
UV irradiation stimulates histone acetylation and chromatin remodeling at a repressed yeast locus. Proc Natl Acad Sci U S A (2005) 1.43
Yeast histone H2A and H2B amino termini have interchangeable functions. Cell (1986) 1.40
Dynamic changes in protein-protein interaction and protein phosphorylation probed with amine-reactive isotope tag. Mol Cell Proteomics (2005) 1.39
Yeast G1 DNA damage checkpoint regulation by H2A phosphorylation is independent of chromatin remodeling. Proc Natl Acad Sci U S A (2006) 1.32
A common element involved in transcriptional regulation of two DNA alkylation repair genes (MAG and MGT1) of Saccharomyces cerevisiae. Mol Cell Biol (1993) 1.32
Histone H3 tail clipping regulates gene expression. Nat Struct Mol Biol (2008) 1.30
Role of the Saccharomyces cerevisiae Rad9 protein in sensing and responding to DNA damage. Biochem Soc Trans (2003) 1.29
The biological effects and mode of action of L-canavanine, a structural analogue of L-arginine. Q Rev Biol (1977) 1.27
Intra- and inter-nucleosomal protein-DNA interactions of the core histone tail domains in a model system. J Biol Chem (2003) 1.23
Changes in nuclear protein acetylation in u.v.-damaged human cells. Carcinogenesis (1986) 1.23
Histone H3 tail acetylation modulates ATP-dependent remodeling through multiple mechanisms. Nucleic Acids Res (2011) 1.17
DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiae. Genetics (2013) 1.17
Timing and spacing of ubiquitin-dependent DNA damage bypass. FEBS Lett (2011) 1.14
Low- and high-resolution mapping of DNA damage at specific sites. Methods (2000) 1.10
Rad6-Rad18 mediates a eukaryotic SOS response by ubiquitinating the 9-1-1 checkpoint clamp. Cell (2008) 1.10
Signal transduction: how rad53 kinase is activated. Curr Biol (2005) 1.09
A domain of Rad9 specifically required for activation of Chk1 in budding yeast. J Cell Sci (2004) 1.06
DNA damage-induced gene expression in Saccharomyces cerevisiae. FEMS Microbiol Rev (2008) 1.03
Intra- and inter-nucleosome interactions of the core histone tail domains in higher-order chromatin structure. Chromosoma (2013) 1.02
DNA damage checkpoints are involved in postreplication repair. Genetics (2006) 0.98
Genome-wide analysis identifies MYND-domain protein Mub1 as an essential factor for Rpn4 ubiquitylation. Mol Cell Biol (2007) 0.95
Evidence that the histone methyltransferase Dot1 mediates global genomic repair by methylating histone H3 on lysine 79. J Biol Chem (2011) 0.95
The DNA damage checkpoint response to replication stress: A Game of Forks. Front Genet (2013) 0.94
A single amino acid change in histone H4 enhances UV survival and DNA repair in yeast. Nucleic Acids Res (2008) 0.92
Mutagenesis of pairwise combinations of histone amino-terminal tails reveals functional redundancy in budding yeast. Proc Natl Acad Sci U S A (2012) 0.90
Reversal of PCNA ubiquitylation by Ubp10 in Saccharomyces cerevisiae. PLoS Genet (2012) 0.88
Pdr3 is required for DNA damage induction of MAG1 and DDI1 via a bi-directional promoter element. Nucleic Acids Res (2004) 0.87
Improved method for measuring the ensemble average of strand breaks in genomic DNA. Environ Mol Mutagen (2001) 0.86
Differential regulation of two closely clustered yeast genes, MAG1 and DDI1, by cell-cycle checkpoints. Nucleic Acids Res (1998) 0.85
Proficient repair in chromatin remodeling defective ino80 mutants of Saccharomyces cerevisiae highlights replication defects as the main contributor to DNA damage sensitivity. DNA Repair (Amst) (2010) 0.81
Proteasome inhibition enhances resistance to DNA damage via upregulation of Rpn4-dependent DNA repair genes. FEBS Lett (2013) 0.79
Histone ubiquitylation and its roles in transcription and DNA damage response. DNA Repair (Amst) (2015) 0.78