Published in Curr Biol on August 09, 2005
The checkpoint clamp activates Mec1 kinase during initiation of the DNA damage checkpoint. Mol Cell (2006) 2.27
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Rif1 and rif2 inhibit localization of tel1 to DNA ends. Mol Cell (2009) 2.09
Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage. Mol Cell (2008) 1.94
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Slx4 regulates DNA damage checkpoint-dependent phosphorylation of the BRCT domain protein Rtt107/Esc4. Mol Biol Cell (2005) 1.66
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Yeast DNA replication protein Dpb11 activates the Mec1/ATR checkpoint kinase. J Biol Chem (2008) 1.61
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Dpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitment. EMBO J (2011) 1.28
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Reconstitution of human claspin-mediated phosphorylation of Chk1 by the ATR (ataxia telangiectasia-mutated and rad3-related) checkpoint kinase. J Biol Chem (2009) 1.18
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Role of the Saccharomyces cerevisiae Rad53 checkpoint kinase in signaling double-strand breaks during the meiotic cell cycle. Mol Cell Biol (2008) 0.98
Dephosphorylation of gamma H2A by Glc7/protein phosphatase 1 promotes recovery from inhibition of DNA replication. Mol Cell Biol (2010) 0.97
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The Saccharomyces cerevisiae 14-3-3 proteins Bmh1 and Bmh2 directly influence the DNA damage-dependent functions of Rad53. Proc Natl Acad Sci U S A (2007) 0.97
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Replication checkpoint: tuning and coordination of replication forks in s phase. Genes (Basel) (2013) 0.95
S-phase checkpoint pathways stimulate the mobility of the retrovirus-like transposon Ty1. Mol Cell Biol (2007) 0.93
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The spindle assembly checkpoint regulates the phosphorylation state of a subset of DNA checkpoint proteins in Saccharomyces cerevisiae. Mol Cell Biol (2006) 0.92
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Regulation of Mec1 kinase activity by the SWI/SNF chromatin remodeling complex. Genes Dev (2015) 0.90
Protein phosphatases pph3, ptc2, and ptc3 play redundant roles in DNA double-strand break repair by homologous recombination. Mol Cell Biol (2010) 0.89
An essential function for the ATR-activation-domain (AAD) of TopBP1 in mouse development and cellular senescence. PLoS Genet (2013) 0.88
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Subtelomere-binding protein Tbf1 and telomere-binding protein Rap1 collaborate to inhibit localization of the Mre11 complex to DNA ends in budding yeast. Mol Biol Cell (2011) 0.85
Requirement of the FATC domain of protein kinase Tel1 for localization to DNA ends and target protein recognition. Mol Biol Cell (2015) 0.85
Dominant TEL1-hy mutations compensate for Mec1 lack of functions in the DNA damage response. Mol Cell Biol (2007) 0.84
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Ddc2 mediates Mec1 activation through a Ddc1- or Dpb11-independent mechanism. PLoS Genet (2014) 0.83
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The Saccharomyces cerevisiae F-box protein Dia2 is a mediator of S-phase checkpoint recovery from DNA damage. Genetics (2012) 0.83
Damage-specific modification of PCNA. Cell Cycle (2010) 0.83
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The Saccharomyces cerevisiae RAD9, RAD17 and RAD24 genes are required for suppression of mutagenic post-replicative repair during chronic DNA damage. DNA Repair (Amst) (2010) 0.82
Saccharomyces CDK1 phosphorylates Rad53 kinase in metaphase, influencing cellular morphogenesis. J Biol Chem (2009) 0.81
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Genome maintenance functions of the INO80 chromatin remodeller. Philos Trans R Soc Lond B Biol Sci (2017) 0.78
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Interplay between histone H3 lysine 56 deacetylation and chromatin modifiers in response to DNA damage. Genetics (2015) 0.78
Mutations in the Non-Catalytic Subunit Dpb2 of DNA Polymerase Epsilon Affect the Nrm1 Branch of the DNA Replication Checkpoint. PLoS Genet (2017) 0.78
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A Rad53 independent function of Rad9 becomes crucial for genome maintenance in the absence of the Recq helicase Sgs1. PLoS One (2013) 0.77
DNA resection proteins Sgs1 and Exo1 are required for G1 checkpoint activation in budding yeast. DNA Repair (Amst) (2013) 0.77
Deacetylase Rpd3 facilitates checkpoint adaptation by preventing Rad53 overactivation. Mol Cell Biol (2013) 0.77
Relationships between chromatin remodeling and DNA damage repair induced by 8-methoxypsoralen and UVA in yeast Saccharomyces cerevisiae. Genet Mol Biol (2012) 0.77
The C-terminal residues of Saccharomyces cerevisiae Mec1 are required for its localization, stability, and function. G3 (Bethesda) (2013) 0.77
Cell cycle regulation by checkpoints. Methods Mol Biol (2014) 0.77
Drug-sensitive DNA polymerase δ reveals a role for mismatch repair in checkpoint activation in yeast. Genetics (2011) 0.76
Use of quantitative mass spectrometric analysis to elucidate the mechanisms of phospho-priming and auto-activation of the checkpoint kinase Rad53 in vivo. Mol Cell Proteomics (2013) 0.76
Asf1 facilitates dephosphorylation of Rad53 after DNA double-strand break repair. Genes Dev (2016) 0.76
Phosphatase complex Pph3/Psy2 is involved in regulation of efficient non-homologous end-joining pathway in the yeast Saccharomyces cerevisiae. PLoS One (2014) 0.76
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The amino-terminal tails of histones H2A and H3 coordinate efficient base excision repair, DNA damage signaling and postreplication repair in Saccharomyces cerevisiae. Nucleic Acids Res (2015) 0.76
Multi-BRCT scaffolds use distinct strategies to support genome maintenance. Cell Cycle (2016) 0.76
Hsp90 induces increased genomic instability toward DNA-damaging agents by tuning down RAD53 transcription. Mol Biol Cell (2016) 0.75
The Knowns Unknowns: Exploring the Homologous Recombination Repair Pathway in Toxoplasma gondii. Front Microbiol (2016) 0.75
A cell cycle-independent mode of the Rad9-Dpb11 interaction is induced by DNA damage. Sci Rep (2017) 0.75
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Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science (2007) 7.61
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell (2009) 6.89
Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains. Mol Cell (2003) 6.44
Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature (2005) 6.40
A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature (2002) 6.19
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell (2009) 5.96
Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression. Mol Cell Biol (2002) 5.42
Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry. Proc Natl Acad Sci U S A (2007) 5.09
The CRAPome: a contaminant repository for affinity purification-mass spectrometry data. Nat Methods (2013) 4.34
A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery. Nature (2005) 4.33
Novel linear quadrupole ion trap/FT mass spectrometer: performance characterization and use in the comparative analysis of histone H3 post-translational modifications. J Proteome Res (2004) 4.32
Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity. Curr Biol (2004) 4.20
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Mitosis inhibits DNA double-strand break repair to guard against telomere fusions. Science (2014) 3.31
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A neutral loss activation method for improved phosphopeptide sequence analysis by quadrupole ion trap mass spectrometry. Anal Chem (2004) 3.08
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Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesis. Sci Signal (2010) 2.79
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N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis. Nat Cell Biol (2007) 2.36
An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme. Cell (2011) 2.35
Insulin controls subcellular localization and multisite phosphorylation of the phosphatidic acid phosphatase, lipin 1. J Biol Chem (2006) 2.32
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The ubiquitous role of ubiquitin in the DNA damage response. DNA Repair (Amst) (2010) 1.94
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