Published in Nat Commun on April 22, 2015
MIPs and Aptamers for Recognition of Proteins in Biomimetic Sensing. Biosensors (Basel) (2016) 0.87
Structural basis for specific inhibition of Autotaxin by a DNA aptamer. Nat Struct Mol Biol (2016) 0.83
Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor. Nat Chem Biol (2016) 0.80
Mechanisms of Regulation of the Chemokine-Receptor Network. Int J Mol Sci (2017) 0.78
Liver macrophages in tissue homeostasis and disease. Nat Rev Immunol (2017) 0.78
Chemokines and their receptors: insights from molecular modeling and crystallography. Curr Opin Pharmacol (2016) 0.76
Stop chronic kidney disease progression: Time is approaching. World J Nephrol (2016) 0.75
Aptamers: A Feasible Technology in Cancer Immunotherapy. J Immunol Res (2016) 0.75
Aptamers in Therapeutics. J Clin Diagn Res (2016) 0.75
Biostable L-DNAzyme for Sensing of Metal Ions in Biological Systems. Anal Chem (2016) 0.75
Structural basis for IL-1α recognition by a modified DNA aptamer that specifically inhibits IL-1α signaling. Nat Commun (2017) 0.75
The Cambridge Structural Database: a quarter of a million crystal structures and rising. Acta Crystallogr B (2002) 234.73
Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr D Biol Crystallogr (1997) 137.43
UCSF Chimera--a visualization system for exploratory research and analysis. J Comput Chem (2004) 112.47
Features and development of Coot. Acta Crystallogr D Biol Crystallogr (2010) 89.46
Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res (2003) 77.89
Overview of the CCP4 suite and current developments. Acta Crystallogr D Biol Crystallogr (2011) 67.55
XDS. Acta Crystallogr D Biol Crystallogr (2010) 67.46
Inference of macromolecular assemblies from crystalline state. J Mol Biol (2007) 44.95
REFMAC5 for the refinement of macromolecular crystal structures. Acta Crystallogr D Biol Crystallogr (2011) 39.32
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science (1990) 35.96
Integration, scaling, space-group assignment and post-refinement. Acta Crystallogr D Biol Crystallogr (2010) 23.35
Towards automated crystallographic structure refinement with phenix.refine. Acta Crystallogr D Biol Crystallogr (2012) 11.31
Human chemokines: an update. Annu Rev Immunol (1997) 8.43
Substructure search procedures for macromolecular structures. Acta Crystallogr D Biol Crystallogr (2003) 6.85
LigPlot+: multiple ligand-protein interaction diagrams for drug discovery. J Chem Inf Model (2011) 6.49
Decision-making in structure solution using Bayesian estimates of map quality: the PHENIX AutoSol wizard. Acta Crystallogr D Biol Crystallogr (2009) 6.47
Chemokines and disease. Nat Immunol (2001) 5.62
Aptamers as therapeutics. Nat Rev Drug Discov (2010) 5.36
3DNA: a versatile, integrated software system for the analysis, rebuilding and visualization of three-dimensional nucleic-acid structures. Nat Protoc (2008) 4.61
Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines. Proc Natl Acad Sci U S A (2003) 3.77
Chemokine: receptor structure, interactions, and antagonism. Annu Rev Immunol (2007) 3.43
Geometry of metal-ligand interactions in proteins. Acta Crystallogr D Biol Crystallogr (2001) 3.20
MCP-1: chemoattractant with a role beyond immunity: a review. Clin Chim Acta (2010) 2.29
Data mining of metal ion environments present in protein structures. J Inorg Biochem (2008) 2.14
Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury. Gut (2011) 2.06
Validation of metal-binding sites in macromolecular structures with the CheckMyMetal web server. Nat Protoc (2013) 1.85
Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1: implications for structure and function in vivo. J Biol Chem (2004) 1.69
Protein-RNA interactions: exploring binding patterns with a three-dimensional superposition analysis of high resolution structures. Bioinformatics (2006) 1.51
Spiegelmer inhibition of CCL2/MCP-1 ameliorates lupus nephritis in MRL-(Fas)lpr mice. J Am Soc Nephrol (2007) 1.44
Contribution of cation-pi interactions to the stability of protein-DNA complexes. J Mol Biol (2000) 1.43
Identification of residues in the monocyte chemotactic protein-1 that contact the MCP-1 receptor, CCR2. Biochemistry (1999) 1.40
Phase 2 study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 (CCL2), in metastatic castration-resistant prostate cancer. Invest New Drugs (2012) 1.38
Late onset of Ccl2 blockade with the Spiegelmer mNOX-E36-3'PEG prevents glomerulosclerosis and improves glomerular filtration rate in db/db mice. Am J Pathol (2008) 1.24
Heteronuclear (1H, 13C, 15N) NMR assignments and solution structure of the monocyte chemoattractant protein-1 (MCP-1) dimer. Biochemistry (1996) 1.23
The structure of MCP-1 in two crystal forms provides a rare example of variable quaternary interactions. Nat Struct Biol (1997) 1.22
A first-in-human, first-in-class, phase I study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 in patients with solid tumors. Cancer Chemother Pharmacol (2013) 1.19
Targeting monocyte chemoattractant protein-1 signalling in disease. Expert Opin Ther Targets (2003) 1.19
Identification of surface residues of the monocyte chemotactic protein 1 that affect signaling through the receptor CCR2. Biochemistry (1999) 1.14
Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation. J Biol Chem (1998) 1.13
Structural characterization of a monomeric chemokine: monocyte chemoattractant protein-3. FEBS Lett (1996) 1.12
Lysine 58 and histidine 66 at the C-terminal alpha-helix of monocyte chemoattractant protein-1 are essential for glycosaminoglycan binding. J Biol Chem (1998) 1.05
Metal ion binding to RNA. Met Ions Life Sci (2011) 1.03
Cation-pi/H-bond stair motifs at protein-DNA interfaces. J Mol Biol (2002) 1.00
Complete crystal structure of monocyte chemotactic protein-2, a CC chemokine that interacts with multiple receptors. Biochemistry (2000) 0.99
RNA aptamers and spiegelmers: synthesis, purification, and post-synthetic PEG conjugation. Curr Protoc Nucleic Acid Chem (2011) 0.99
Structure activity relationships of monocyte chemoattractant proteins in complex with a blocking antibody. Protein Eng Des Sel (2006) 0.96
Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer. Nat Commun (2015) 0.91
Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888. Mol Immunol (2012) 0.85
Selenium derivatization of nucleic acids for phase and structure determination in nucleic acid X-ray crystallography. Int J Mol Sci (2008) 0.84
Chemokine oligomerization in cell signaling and migration. Prog Mol Biol Transl Sci (2013) 0.83
Structure of the hydrated and dimethyl sulfoxide solvated rubidium ions in solution. Inorg Chem (2004) 0.83
Structure of human monocyte chemoattractant protein 4 (MCP-4/CCL13). Acta Crystallogr D Biol Crystallogr (2008) 0.77
Turning mirror-image oligonucleotides into drugs: the evolution of Spiegelmer(®) therapeutics. Drug Discov Today (2014) 0.91
Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer. Nat Commun (2015) 0.91
Latest methods of fluorescence-based protein crystal identification. Acta Crystallogr F Struct Biol Commun (2015) 0.82
Outwitting EF-Tu and the ribosome: translation with d-amino acids. Nucleic Acids Res (2015) 0.78
Expanding biohybrid-mediated asymmetric catalysis into the realm of RNA. Chem Commun (Camb) (2016) 0.75
Liquid Crystal Ordering and Isotropic Gelation in Solutions of Four-Base-Long DNA Oligomers. ACS Nano (2016) 0.75