Published in J Biol Chem on March 18, 2004
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Identification of proteoglycans as the APRIL-specific binding partners. J Exp Med (2005) 2.03
Chemokine receptor antagonists: overcoming developmental hurdles. Nat Rev Drug Discov (2008) 1.64
Structural and functional basis of CXCL12 (stromal cell-derived factor-1 alpha) binding to heparin. J Biol Chem (2007) 1.58
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The C terminus of mouse monocyte chemoattractant protein 1 (MCP1) mediates MCP1 dimerization while blocking its chemotactic potency. J Biol Chem (2010) 1.02
Monocyte chemoattractant protein-1 and the blood-brain barrier. Cell Mol Life Sci (2013) 1.02
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Synthetic peptide fragment (65-76) of monocyte chemotactic protein-1 (MCP-1) inhibits MCP-1 binding to heparin and possesses anti-inflammatory activity in stable angina patients after coronary stenting. Inflamm Res (2011) 0.96
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MCP-1 binds to oxidized LDL and is carried by lipoprotein(a) in human plasma. J Lipid Res (2013) 0.95
The antimicrobial activity of CCL28 is dependent on C-terminal positively-charged amino acids. Eur J Immunol (2010) 0.94
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Glycosaminoglycan analogs as a novel anti-inflammatory strategy. Front Immunol (2012) 0.89
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The Anti-inflammatory Protein TSG-6 Regulates Chemokine Function by Inhibiting Chemokine/Glycosaminoglycan Interactions. J Biol Chem (2016) 0.87
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Peripheral blood cell signatures of Plasmodium falciparum infection during pregnancy. PLoS One (2012) 0.84
Crystal structure of a mirror-image L-RNA aptamer (Spiegelmer) in complex with the natural L-protein target CCL2. Nat Commun (2015) 0.83
Structural NMR of protein oligomers using hybrid methods. J Struct Biol (2010) 0.83
Chemokine oligomerization in cell signaling and migration. Prog Mol Biol Transl Sci (2013) 0.83
Heparin-immobilized microspheres for the capture of cytokines. Anal Bioanal Chem (2010) 0.83
Chemokine receptor oligomerization and allostery. Prog Mol Biol Transl Sci (2013) 0.82
An Ion Mobility-Mass Spectrometry Investigation of Monocyte Chemoattractant Protein-1. Int J Mass Spectrom (2009) 0.81
A competitive binding study of chemokine, sulfated receptor, and glycosaminoglycan interactions by nano-electrospray ionization mass spectrometry. Anal Biochem (2010) 0.81
Structure-based design of decoy chemokines as a way to explore the pharmacological potential of glycosaminoglycans. Br J Pharmacol (2012) 0.81
Characterization of the interactions of vMIP-II, and a dimeric variant of vMIP-II, with glycosaminoglycans. Biochemistry (2010) 0.80
Examination of Glycosaminoglycan Binding Sites on the XCL1 Dimer. Biochemistry (2016) 0.80
Mouse MCP1 C-terminus inhibits human MCP1-induced chemotaxis and BBB compromise. J Neurochem (2011) 0.80
Ion mobility mass spectrometry coupled with rapid protein threading predictor structure prediction and collision-induced dissociation for probing chemokine conformation and stability. Anal Chem (2012) 0.80
Oligomerized, filamentous surface presentation of RANTES/CCL5 on vascular endothelial cells. Sci Rep (2015) 0.79
Interference with glycosaminoglycan-chemokine interactions with a probe to alter leukocyte recruitment and inflammation in vivo. PLoS One (2014) 0.77
New paradigms in chemokine receptor signal transduction: Moving beyond the two-site model. Biochem Pharmacol (2016) 0.77
Heparin alters viral serpin, serp-1, anti-thrombolytic activity to anti-thrombotic activity. Open Biochem J (2008) 0.77
Breast cancer: coordinated regulation of CCL2 secretion by intracellular glycosaminoglycans and chemokine motifs. Neoplasia (2014) 0.77
Inhibition of migration of monocytes and granulocytes in vivo by the peptide corresponding to sequence 65-76 of monocyte chemotactic protein-1 (MCP-1). Dokl Biochem Biophys (2007) 0.77
The peptide of sequence 66-77 of monocytic chemotactic protein (MCP-1) inhibits inflammation in experimental animals. Dokl Biol Sci (2006) 0.77
Effect of the C-terminal domain peptide fragment (65-76) of monocytic chemotactic protein-1 (MCP-1) on the interaction between MCP-1 and heparin. Dokl Biol Sci (2010) 0.77
Mouse monocyte chemoattractant protein 1 (MCP1) functions as a monomer. Int J Biochem Cell Biol (2014) 0.76
In-vitro suppression of IL-6 and IL-8 release from human pulmonary epithelial cells by non-anticoagulant fraction of enoxaparin. PLoS One (2015) 0.76
Interaction of endothelial cells with macrophages-linking molecular and metabolic signaling. Pflugers Arch (2017) 0.76
Rodent herpesvirus Peru encodes a secreted chemokine decoy receptor. J Virol (2013) 0.75
Differential structural remodelling of heparan sulfate by chemokines: the role of chemokine oligomerization. Open Biol (2017) 0.75
Structural Evidence for the Tetrameric Assembly of Chemokine CCL11 and the Glycosaminoglycan Arixtra™. Biomolecules (2013) 0.75
CCL2 nitration is a negative regulator of chemokine-mediated inflammation. Sci Rep (2017) 0.75
A three-dimensional in vitro model to demonstrate the haptotactic effect of monocyte chemoattractant protein-1 on atherosclerosis-associated monocyte migration. Int J Biol Macromol (2016) 0.75
Glycosaminoglycan Interactions with Chemokines Add Complexity to a Complex System. Pharmaceuticals (Basel) (2017) 0.75
Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science (2010) 10.30
Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines. Proc Natl Acad Sci U S A (2003) 3.77
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Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice. Nat Med (2009) 2.15
Construction of a fluorescent biosensor family. Protein Sci (2002) 2.07
The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer. Nat Rev Cancer (2013) 2.05
Chemerin activation by serine proteases of the coagulation, fibrinolytic, and inflammatory cascades. J Biol Chem (2005) 2.03
Chemokines and cancer: migration, intracellular signalling and intercellular communication in the microenvironment. Biochem J (2008) 1.83
Mast cell-expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis. J Exp Med (2008) 1.74
Energy functions for protein design: adjustment with protein-protein complex affinities, models for the unfolded state, and negative design of solubility and specificity. J Mol Biol (2005) 1.67
The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors. Structure (2004) 1.42
Chemoattractants, extracellular proteases, and the integrated host defense response. Exp Hematol (2006) 1.37
Chemokine-like receptor 1 expression by macrophages in vivo: regulation by TGF-beta and TLR ligands. Exp Hematol (2006) 1.36
Ordered nanoparticle arrays formed on engineered chaperonin protein templates. Nat Mater (2002) 1.35
A proteomic snapshot of the human heat shock protein 90 interactome. FEBS Lett (2005) 1.33
Inhibition of monocyte chemoattractant protein-1 ameliorates rat adjuvant-induced arthritis. J Immunol (2008) 1.30
Structural basis of chemokine sequestration by a herpesvirus decoy receptor. Cell (2002) 1.29
Chemokine-glycosaminoglycan binding: specificity for CCR2 ligand binding to highly sulfated oligosaccharides using FTICR mass spectrometry. J Biol Chem (2005) 1.21
Airway hyperresponsiveness, but not airway remodeling, is attenuated during chronic pulmonary allergic responses to Aspergillus in CCR4-/- mice. FASEB J (2002) 1.19
An object-oriented library for computational protein design. J Comput Chem (2007) 1.17
Energy functions for protein design I: efficient and accurate continuum electrostatics and solvation. Protein Sci (2004) 1.17
Structural and computational characterization of the SHV-1 beta-lactamase-beta-lactamase inhibitor protein interface. J Biol Chem (2006) 1.16
Different affinities of glycosaminoglycan oligosaccharides for monomeric and dimeric interleukin-8: a model for chemokine regulation at inflammatory sites. Biochemistry (2002) 1.16
Elucidating the CXCL12/CXCR4 signaling network in chronic lymphocytic leukemia through phosphoproteomics analysis. PLoS One (2010) 1.15
Heterodimerization of CCR2 chemokines and regulation by glycosaminoglycan binding. J Biol Chem (2006) 1.12
Oligomerization of RANTES is required for CCR1-mediated arrest but not CCR5-mediated transmigration of leukocytes on inflamed endothelium. Blood (2003) 1.11
Structure of M11L: A myxoma virus structural homolog of the apoptosis inhibitor, Bcl-2. Protein Sci (2007) 1.11
Chemokine-receptor interactions: GPCRs, glycosaminoglycans and viral chemokine binding proteins. Adv Protein Chem (2004) 1.10
A new monocyte chemotactic protein-1/chemokine CC motif ligand-2 competitor limiting neointima formation and myocardial ischemia/reperfusion injury in mice. J Am Coll Cardiol (2010) 1.09
Characterization of the chemokine CXCL11-heparin interaction suggests two different affinities for glycosaminoglycans. J Biol Chem (2010) 1.07
An engineered monomer of CCL2 has anti-inflammatory properties emphasizing the importance of oligomerization for chemokine activity in vivo. J Leukoc Biol (2008) 1.07
Regulation of chemerin bioactivity by plasma carboxypeptidase N, carboxypeptidase B (activated thrombin-activable fibrinolysis inhibitor), and platelets. J Biol Chem (2008) 1.06
Oligomeric structure of the chemokine CCL5/RANTES from NMR, MS, and SAXS data. Structure (2011) 1.05
The molecular chaperone Hsp90 modulates intermediate steps of amyloid assembly of the Parkinson-related protein alpha-synuclein. J Biol Chem (2009) 1.05
Differences in the glycosylation of recombinant proteins expressed in HEK and CHO cells. J Biotechnol (2012) 1.05
Chronic lymphocytic leukemia cells receive RAF-dependent survival signals in response to CXCL12 that are sensitive to inhibition by sorafenib. Blood (2010) 1.04
Sorafenib-induced apoptosis of chronic lymphocytic leukemia cells is associated with downregulation of RAF and myeloid cell leukemia sequence 1 (Mcl-1). Mol Med (2012) 1.04
Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface. J Mol Biol (2008) 1.03
A structural and dynamic model for the interaction of interleukin-8 and glycosaminoglycans: support from isothermal fluorescence titrations. Proteins (2004) 1.01
Chronic expression of monocyte chemoattractant protein-1 in the central nervous system causes delayed encephalopathy and impaired microglial function in mice. FASEB J (2005) 1.01
Staphylococcus aureus-derived staphopain B, a potent cysteine protease activator of plasma chemerin. J Immunol (2007) 1.01
A proteomic approach towards the Hsp90-dependent ubiquitinylated proteome. Proteomics (2007) 0.98
Interleukin-8 binds to syndecan-2 on human endothelial cells. Biochem J (2004) 0.98
A critical role for lymphatic endothelial heparan sulfate in lymph node metastasis. Mol Cancer (2010) 0.97
Formation of the pyridazine natural product azamerone by biosynthetic rearrangement of an aryl diazoketone. Angew Chem Int Ed Engl (2009) 0.97
Inactivation of heparan sulfate 2-O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice. Blood (2012) 0.97
HER2-targeted liposomal doxorubicin displays enhanced anti-tumorigenic effects without associated cardiotoxicity. Toxicol Appl Pharmacol (2012) 0.96
Structural and biochemical characterization of the interaction between KPC-2 beta-lactamase and beta-lactamase inhibitor protein. Biochemistry (2009) 0.96
Structure of the minimal interface between ApoE and LRP. J Mol Biol (2010) 0.95
Regulation of chemerin chemoattractant and antibacterial activity by human cysteine cathepsins. J Immunol (2011) 0.95
Rationally evolving MCP-1/CCL2 into a decoy protein with potent anti-inflammatory activity in vivo. J Biol Chem (2010) 0.95
MCP-1 binds to oxidized LDL and is carried by lipoprotein(a) in human plasma. J Lipid Res (2013) 0.95
Engineering the glycosaminoglycan-binding affinity, kinetics and oligomerization behavior of RANTES: a tool for generating chemokine-based glycosaminoglycan antagonists. Protein Eng Des Sel (2009) 0.94
TSG-6 inhibits neutrophil migration via direct interaction with the chemokine CXCL8. J Immunol (2014) 0.93
Expression, purification and in vitro functional reconstitution of the chemokine receptor CCR1. Protein Expr Purif (2009) 0.93
Chemokine degradation by the Group A streptococcal serine proteinase ScpC can be reconstituted in vitro and requires two separate domains. Biochem J (2009) 0.93
Chapter 4. Interactions of chemokines with glycosaminoglycans. Methods Enzymol (2009) 0.92
NMR analysis of the structure, dynamics, and unique oligomerization properties of the chemokine CCL27. J Biol Chem (2010) 0.92
Examination of MCP-1 (CCL2) partitioning and presentation during transendothelial leukocyte migration. Lab Invest (2004) 0.91
Expression and agonist responsiveness of CXCR3 variants in human T lymphocytes. Immunology (2011) 0.90
A biophysical insight into the RANTES-glycosaminoglycan interaction. Biochim Biophys Acta (2009) 0.90
Investigating the effect of VEGF glycosylation on glycosaminoglycan binding and protein unfolding. Biochem Biophys Res Commun (2005) 0.89
A novel CXCL8 protein-based antagonist in acute experimental renal allograft damage. Mol Immunol (2009) 0.89
Emerging concepts and approaches for chemokine-receptor drug discovery. Expert Opin Drug Discov (2010) 0.89
A rapid and efficient way to obtain modified chemokines for functional and biophysical studies. Cytokine (2011) 0.89
Analysis of an orf virus chemokine-binding protein: Shifting ligand specificities among a family of poxvirus viroceptors. Proc Natl Acad Sci U S A (2003) 0.89
Treatment with Evasin-3 reduces atherosclerotic vulnerability for ischemic stroke, but not brain injury in mice. J Cereb Blood Flow Metab (2012) 0.88
Single administration of the CXC chemokine-binding protein Evasin-3 during ischemia prevents myocardial reperfusion injury in mice. Arterioscler Thromb Vasc Biol (2010) 0.88
Chemokines bind to sulfatides as revealed by surface plasmon resonance. Biochim Biophys Acta (2005) 0.88
The chemokine receptor CCR1 is constitutively active, which leads to G protein-independent, β-arrestin-mediated internalization. J Biol Chem (2013) 0.87
Discovery, optimization, and pharmacological characterization of novel heteroaroylphenylureas antagonists of C-C chemokine ligand 2 function. J Med Chem (2011) 0.87
Selective binding and presentation of CCL5 by discrete tissue microenvironments during renal inflammation. J Am Soc Nephrol (2007) 0.87
Opportunities for functional selectivity in GPCR antibodies. Biochem Pharmacol (2012) 0.86
Proteoglycanomics: tools to unravel the biological function of glycosaminoglycans. Proteomics (2007) 0.86
The rosettazyme: a synthetic cellulosome. J Biotechnol (2009) 0.85
Sulfopeptide probes of the CXCR4/CXCL12 interface reveal oligomer-specific contacts and chemokine allostery. ACS Chem Biol (2013) 0.85
Intracellular localization of a group II chaperonin indicates a membrane-related function. Proc Natl Acad Sci U S A (2003) 0.85
Solution structure and dynamics of melanoma inhibitory activity protein. J Biomol NMR (2002) 0.84
NMR assignment of human chemerin, a novel chemoattractant. Biomol NMR Assign (2007) 0.84
Phosphoproteomic analysis of chemokine signaling networks. Methods Enzymol (2009) 0.84
Distinct chemokine receptor axes regulate Th9 cell trafficking to allergic and autoimmune inflammatory sites. J Immunol (2013) 0.84
Site-selective dual modification of periplasmic binding proteins for sensing applications. Biosens Bioelectron (2010) 0.84
A self-assembling protein template for constrained synthesis and patterning of nanoparticle arrays. J Am Chem Soc (2005) 0.84
The basic residue cluster (55)KKWVR(59) in CCL5 is required for in vivo biologic function. Mol Immunol (2009) 0.84
Chemokine oligomerization in cell signaling and migration. Prog Mol Biol Transl Sci (2013) 0.83
Comparative membrane proteome analysis of three Borrelia species. Proteomics (2012) 0.83
Glycanogenomics: a qPCR-approach to investigate biological glycan function. Biochem Biophys Res Commun (2008) 0.83
Evasin-4, a tick-derived chemokine-binding protein with broad selectivity can be modified for use in preclinical disease models. FEBS J (2013) 0.83
CCR1 and CCR5 chemokine receptors are involved in fever induced by LPS (E. coli) and RANTES in rats. Brain Res (2007) 0.82
Specificity and cooperativity at β-lactamase position 104 in TEM-1/BLIP and SHV-1/BLIP interactions. Proteins (2011) 0.82
Chemokine receptor oligomerization and allostery. Prog Mol Biol Transl Sci (2013) 0.82
Interference with oligomerization and glycosaminoglycan binding of the chemokine CCL5 improves experimental liver injury. PLoS One (2012) 0.82