Expression of Lysine-specific demethylase 1 in human epithelial ovarian cancer.

PubWeight™: 0.80‹?›

🔗 View Article (PMC 4429353)

Published in J Ovarian Res on May 09, 2015

Authors

Cong Chen1, Jing Ge2, Qibin Lu3, Guoqiang Ping4, Chunqing Yang5, Xuefeng Fang6

Author Affiliations

1: Department of Gynecology of Traditional Chinese Medicine, Jiangsu Provincial Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu, 210029, China. chencongdr@sina.com.
2: Department of Endocrinology, Jiangsu Provincial Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu Province, 210029, China. gejingtcm@126.com.
3: Department of Gynecology of Traditional Chinese Medicine, Jiangsu Provincial Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu, 210029, China. luqibinwen@163.com.
4: Department of Pathology, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, China. Pingguoqiang@yeah.net.
5: Department of Pathology, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, China. yangchunqingnj@163.com.
6: Department of Medical Oncology, Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou, Zhejiang, 310009, China. xffang@zju.edu.cn.

Articles cited by this

Cancer statistics, 2013. CA Cancer J Clin (2013) 84.72

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell (2004) 21.30

LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription. Nature (2005) 8.53

Ovarian cancer. Annu Rev Pathol (2009) 4.92

p53 is regulated by the lysine demethylase LSD1. Nature (2007) 4.53

Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers. Int J Cancer (2011) 2.42

Identification of cell-active lysine specific demethylase 1-selective inhibitors. J Am Chem Soc (2009) 1.56

Over-expression of LSD1 promotes proliferation, migration and invasion in non-small cell lung cancer. PLoS One (2012) 1.56

Impairment of prostate cancer cell growth by a selective and reversible lysine-specific demethylase 1 inhibitor. Int J Cancer (2012) 1.18

Genetic alterations and changes in expression of histone demethylases in prostate cancer. Prostate (2010) 1.12

Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion. Cancer Res (2012) 1.11

LSD1-mediated epigenetic modification contributes to proliferation and metastasis of colon cancer. Br J Cancer (2013) 1.09

Carcinogen-induced histone alteration in normal human mammary epithelial cells. Carcinogenesis (2007) 1.06

High nuclear expression levels of histone-modifying enzymes LSD1, HDAC2 and SIRT1 in tumor cells correlate with decreased survival and increased relapse in breast cancer patients. BMC Cancer (2014) 0.98

Overexpression of lysine specific demethylase 1 predicts worse prognosis in primary hepatocellular carcinoma patients. World J Gastroenterol (2012) 0.97

Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1(DNA methyltransferase 1)-independent manner. Biochem J (2013) 0.96

LSD1 sustains pancreatic cancer growth via maintaining HIF1α-dependent glycolytic process. Cancer Lett (2014) 0.94

Elevated expression of LSD1 (Lysine-specific demethylase 1) during tumour progression from pre-invasive to invasive ductal carcinoma of the breast. BMC Clin Pathol (2012) 0.92

Lysine-specific demethylase 1 (LSD1/KDM1A) contributes to colorectal tumorigenesis via activation of the Wnt/β-catenin pathway by down-regulating Dickkopf-1 (DKK1) [corrected]. PLoS One (2013) 0.92

Analysis of the levels of lysine-specific demethylase 1 (LSD1) mRNA in human ovarian tumors and the effects of chemical LSD1 inhibitors in ovarian cancer cell lines. J Ovarian Res (2013) 0.85

CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression. J Cancer Res Clin Oncol (2014) 0.77