Published in J Cell Biol on May 11, 2015
Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments. Nat Commun (2016) 1.13
A model for coordinating nuclear mechanics and membrane remodeling to support nuclear integrity. Curr Opin Cell Biol (2016) 0.94
Forces, fluctuations, and self-organization in the nucleus. Mol Biol Cell (2015) 0.76
p63 transcription factor regulates nuclear shape and expression of nuclear envelope-associated genes in epidermal keratinocytes. J Invest Dermatol (2017) 0.75
Megan King: A force to be reckoned with. J Cell Biol (2016) 0.75
Cytoskeletal Configuration Modulates Mechanically Induced Changes in Mesenchymal Stem Cell Osteogenesis, Morphology, and Stiffness. Sci Rep (2016) 0.75
Opposing roles for distinct LINC complexes in regulation of the small GTPase RhoA. Mol Biol Cell (2016) 0.75
Implications for Diverse Functions of the LINC Complexes Based on the Structure. Cells (2017) 0.75
Actomyosin and vimentin cytoskeletal networks regulate nuclear shape, mechanics and chromatin organization. Sci Rep (2017) 0.75
Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc Natl Acad Sci U S A (1997) 19.46
Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism. J Cell Biol (2001) 9.73
Coupling of the nucleus and cytoplasm: role of the LINC complex. J Cell Biol (2005) 6.47
The relationship between force and focal complex development. J Cell Biol (2002) 6.26
Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics. Nature (2010) 6.25
Controls of hair follicle cycling. Physiol Rev (2001) 5.49
Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus. Nat Rev Mol Cell Biol (2009) 5.41
Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells. Cell (2005) 4.86
alpha-Catenin as a tension transducer that induces adherens junction development. Nat Cell Biol (2010) 4.42
Mechanical integration of actin and adhesion dynamics in cell migration. Annu Rev Cell Dev Biol (2010) 4.06
Actin cable dynamics and Rho/Rock orchestrate a polarized cytoskeletal architecture in the early steps of assembling a stratified epithelium. Dev Cell (2002) 4.01
Adherens junctions: from molecules to morphogenesis. Nat Rev Mol Cell Biol (2010) 3.97
The C. elegans hook protein, ZYG-12, mediates the essential attachment between the centrosome and nucleus. Cell (2003) 3.78
Adipocyte lineage cells contribute to the skin stem cell niche to drive hair cycling. Cell (2011) 3.68
Linear arrays of nuclear envelope proteins harness retrograde actin flow for nuclear movement. Science (2010) 3.53
Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II-dependent manner. J Cell Biol (2010) 3.25
Nuclear shape, mechanics, and mechanotransduction. Circ Res (2008) 3.12
SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice. Dev Cell (2007) 3.09
ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity. Cell (2008) 2.94
E-cadherin is under constitutive actomyosin-generated tension that is increased at cell-cell contacts upon externally applied stretch. Proc Natl Acad Sci U S A (2012) 2.82
LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins. Cell (2012) 2.79
E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions. EMBO J (2005) 2.72
Cell-ECM traction force modulates endogenous tension at cell-cell contacts. Proc Natl Acad Sci U S A (2011) 2.67
Barrier function of the skin: "la raison d'être" of the epidermis. J Invest Dermatol (2003) 2.45
Basal-to-apical cadherin flow at cell junctions. Nat Cell Biol (2006) 2.33
Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus. Nat Cell Biol (2014) 2.30
Microtubule-induced cortical cell polarity. Genes Dev (2007) 2.28
Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation. Development (2007) 2.27
Cortical F-actin stabilization generates apical-lateral patterns of junctional contractility that integrate cells into epithelia. Nat Cell Biol (2014) 2.26
Spatial regulation of CLASP affinity for microtubules by Rac1 and GSK3beta in migrating epithelial cells. J Cell Biol (2005) 2.24
The interaction between nesprins and sun proteins at the nuclear envelope is critical for force transmission between the nucleus and cytoskeleton. J Biol Chem (2011) 2.21
Nucleokinesis in tangentially migrating neurons comprises two alternating phases: forward migration of the Golgi/centrosome associated with centrosome splitting and myosin contraction at the rear. J Neurosci (2005) 2.20
Desmoplakin: an unexpected regulator of microtubule organization in the epidermis. J Cell Biol (2007) 2.16
Tension is required but not sufficient for focal adhesion maturation without a stress fiber template. J Cell Biol (2012) 2.12
SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice. Proc Natl Acad Sci U S A (2009) 2.07
Desmoglein 4 in hair follicle differentiation and epidermal adhesion: evidence from inherited hypotrichosis and acquired pemphigus vulgaris. Cell (2003) 2.06
Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation. Physiol Rev (2011) 2.06
The nucleoskeleton as a genome-associated dynamic 'network of networks'. Nat Rev Mol Cell Biol (2011) 2.01
Differential positioning of adherens junctions is associated with initiation of epithelial folding. Nature (2012) 1.98
Deconstructing the skin: cytoarchitectural determinants of epidermal morphogenesis. Nat Rev Mol Cell Biol (2011) 1.94
Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin. J Cell Sci (2008) 1.86
Actomyosin is the main driver of interkinetic nuclear migration in the retina. Cell (2009) 1.84
Actin dynamics modulate mechanosensitive immobilization of E-cadherin at adherens junctions. Nat Cell Biol (2014) 1.84
Intermediate filament-membrane attachments function synergistically with actin-dependent contacts to regulate intercellular adhesive strength. J Cell Biol (2002) 1.83
Classical cadherins control nucleus and centrosome position and cell polarity. J Cell Biol (2009) 1.78
Desmoglein 3 anchors telogen hair in the follicle. J Cell Sci (1998) 1.77
KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development. Hum Mol Genet (2010) 1.59
UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration. Dev Biol (2009) 1.32
Cadherin-based intercellular adhesions organize epithelial cell-matrix traction forces. Proc Natl Acad Sci U S A (2012) 1.31
Scaling of traction forces with the size of cohesive cell colonies. Phys Rev Lett (2012) 1.29
Regulation of desmosome assembly in MDCK epithelial cells: coordination of membrane core and cytoplasmic plaque domain assembly at the plasma membrane. J Cell Biol (1991) 1.28
Growing microtubules push the oocyte nucleus to polarize the Drosophila dorsal-ventral axis. Science (2012) 1.27
Actomyosin contraction at the cell rear drives nuclear translocation in migrating cortical interneurons. J Neurosci (2010) 1.23
Binding to F-actin guides cadherin cluster assembly, stability, and movement. J Cell Biol (2013) 1.23
Interfering with the connection between the nucleus and the cytoskeleton affects nuclear rotation, mechanotransduction and myogenesis. Int J Biochem Cell Biol (2010) 1.17
Desmoglein 4 is expressed in highly differentiated keratinocytes and trichocytes in human epidermis and hair follicle. Differentiation (2006) 1.14
The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction. Sci Rep (2013) 1.13
Noncentrosomal microtubules and type II myosins potentiate epidermal cell adhesion and barrier formation. J Cell Biol (2012) 1.12
Keeping the LINC: the importance of nucleocytoskeletal coupling in intracellular force transmission and cellular function. Biochem Soc Trans (2011) 1.11
Structural basis for heteromeric assembly and perinuclear organization of keratin filaments. Nat Struct Mol Biol (2012) 1.10
Lis1 is essential for cortical microtubule organization and desmosome stability in the epidermis. J Cell Biol (2011) 1.10
The nuclear envelope protein Nesprin-2 has roles in cell proliferation and differentiation during wound healing. Nucleus (2012) 0.98
Desmosomal cadherins utilize distinct kinesins for assembly into desmosomes. J Cell Biol (2011) 0.98
Nesprin-3 augments peripheral nuclear localization of intermediate filaments in zebrafish. J Cell Sci (2011) 0.97
Desmosome assembly and dynamics. Trends Cell Biol (2013) 0.96
LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina. PLoS One (2012) 0.95
Interkinetic nuclear migration is centrosome independent and ensures apical cell division to maintain tissue integrity. Dev Cell (2015) 0.92
Formation of adherens junctions leads to the emergence of a tissue-level tension in epithelial monolayers. J Cell Sci (2014) 0.90
Abnormal inner root sheath of the hair follicle in the loose anagen hair syndrome: an ultrastructural study. J Am Acad Dermatol (2011) 0.90
Control of cortical microtubule organization and desmosome stability by centrosomal proteins. Bioarchitecture (2011) 0.88
beta-Catenin protects the epidermis from mechanical stresses. J Cell Biol (2013) 0.87
Microtubule-dependent transport and dynamics of vimentin intermediate filaments. Mol Biol Cell (2015) 0.85