Published in Proc Natl Acad Sci U S A on March 07, 2011
A mechanoresponsive cadherin-keratin complex directs polarized protrusive behavior and collective cell migration. Dev Cell (2011) 2.87
E-cadherin is under constitutive actomyosin-generated tension that is increased at cell-cell contacts upon externally applied stretch. Proc Natl Acad Sci U S A (2012) 2.82
Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility. J Cell Biol (2012) 2.33
Fluid shear stress on endothelial cells modulates mechanical tension across VE-cadherin and PECAM-1. Curr Biol (2013) 2.02
Spatial organization of the extracellular matrix regulates cell-cell junction positioning. Proc Natl Acad Sci U S A (2012) 1.88
Plithotaxis and emergent dynamics in collective cellular migration. Trends Cell Biol (2011) 1.79
A hitchhiker's guide to mechanobiology. Dev Cell (2011) 1.72
Cell origami: self-folding of three-dimensional cell-laden microstructures driven by cell traction force. PLoS One (2012) 1.34
Monolayer stress microscopy: limitations, artifacts, and accuracy of recovered intercellular stresses. PLoS One (2013) 1.34
Cadherin-based intercellular adhesions organize epithelial cell-matrix traction forces. Proc Natl Acad Sci U S A (2012) 1.31
Scaling of traction forces with the size of cohesive cell colonies. Phys Rev Lett (2012) 1.29
Roles of cell confluency and fluid shear in 3-dimensional intracellular forces in endothelial cells. Proc Natl Acad Sci U S A (2012) 1.22
Substrate viscosity enhances correlation in epithelial sheet movement. Biophys J (2011) 1.21
Control of cell-cell forces and collective cell dynamics by the intercellular adhesome. Nat Cell Biol (2015) 1.17
α-catenin cytomechanics--role in cadherin-dependent adhesion and mechanotransduction. J Cell Sci (2014) 1.17
Direct laser manipulation reveals the mechanics of cell contacts in vivo. Proc Natl Acad Sci U S A (2015) 1.13
Cooperative coupling of cell-matrix and cell-cell adhesions in cardiac muscle. Proc Natl Acad Sci U S A (2012) 1.13
Dynamic visualization of α-catenin reveals rapid, reversible conformation switching between tension states. Curr Biol (2014) 1.07
A micropatterning and image processing approach to simplify measurement of cellular traction forces. Acta Biomater (2011) 1.07
Tensegrity, cellular biophysics, and the mechanics of living systems. Rep Prog Phys (2014) 1.06
Flow mechanotransduction regulates traction forces, intercellular forces, and adherens junctions. Am J Physiol Heart Circ Physiol (2012) 1.04
CCM1-ICAP-1 complex controls β1 integrin-dependent endothelial contractility and fibronectin remodeling. J Cell Biol (2013) 1.03
Three functions of cadherins in cell adhesion. Curr Biol (2013) 1.03
Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response. EMBO J (2013) 1.02
Left-right symmetry breaking in tissue morphogenesis via cytoskeletal mechanics. Circ Res (2012) 1.02
High-resolution traction force microscopy. Methods Cell Biol (2014) 1.02
Mapping the dynamics of force transduction at cell-cell junctions of epithelial clusters. Elife (2014) 1.01
Toward single cell traction microscopy within 3D collagen matrices. Exp Cell Res (2013) 1.01
Nuclear-cytoskeletal linkages facilitate cross talk between the nucleus and intercellular adhesions. J Cell Biol (2015) 0.99
Endothelial barrier disruption and recovery is controlled by substrate stiffness. Microvasc Res (2013) 0.97
Measuring cell-generated forces: a guide to the available tools. Nat Methods (2016) 0.95
Epithelial protein lost in neoplasm (EPLIN) interacts with α-catenin and actin filaments in endothelial cells and stabilizes vascular capillary network in vitro. J Biol Chem (2011) 0.94
The role of adhesion energy in controlling cell-cell contacts. Curr Opin Cell Biol (2011) 0.93
Depth-resolved cellular microrheology using HiLo microscopy. Biomed Opt Express (2012) 0.93
Mechanotransduction at the basis of endothelial barrier function. Tissue Barriers (2013) 0.93
Local VE-cadherin mechanotransduction triggers long-ranged remodeling of endothelial monolayers. J Cell Sci (2015) 0.92
E-cadherin-dependent stimulation of traction force at focal adhesions via the Src and PI3K signaling pathways. Biophys J (2012) 0.92
High resolution, large deformation 3D traction force microscopy. PLoS One (2014) 0.91
Dynamic peripheral traction forces balance stable neurite tension in regenerating Aplysia bag cell neurons. Sci Rep (2014) 0.91
Mechanochemical regulation of oscillatory follicle cell dynamics in the developing Drosophila egg chamber. Mol Biol Cell (2014) 0.91
A dynamic cell adhesion surface regulates tissue architecture in growth plate cartilage. Development (2014) 0.90
Formation of adherens junctions leads to the emergence of a tissue-level tension in epithelial monolayers. J Cell Sci (2014) 0.90
Running with neighbors: coordinating cell migration and cell-cell adhesion. Curr Opin Cell Biol (2015) 0.89
Collagen Organization Critical Role in Wound Contraction. Adv Wound Care (New Rochelle) (2012) 0.88
Vinculin, cadherin mechanotransduction and homeostasis of cell-cell junctions. Protoplasma (2012) 0.88
Tension monitoring during epithelial-to-mesenchymal transition links the switch of phenotype to expression of moesin and cadherins in NMuMG cells. PLoS One (2013) 0.87
Rac1/RhoA antagonism defines cell-to-cell heterogeneity during epidermal morphogenesis in nematodes. J Cell Biol (2016) 0.86
The mechanotransduction machinery at work at adherens junctions. Integr Biol (Camb) (2015) 0.86
The role of engineering approaches in analysing cancer invasion and metastasis. Nat Rev Cancer (2013) 0.86
Stiffness-activated GEF-H1 expression exacerbates LPS-induced lung inflammation. PLoS One (2014) 0.85
P-cadherin promotes collective cell migration via a Cdc42-mediated increase in mechanical forces. J Cell Biol (2016) 0.84
Protrusive activity guides changes in cell-cell tension during epithelial cell scattering. Biophys J (2014) 0.84
Three-dimensional analysis of the effect of epidermal growth factor on cell-cell adhesion in epithelial cell clusters. Biophys J (2012) 0.84
A plastic relationship between vinculin-mediated tension and adhesion complex area defines adhesion size and lifetime. Nat Commun (2015) 0.84
Contact inhibition of locomotion determines cell-cell and cell-substrate forces in tissues. Proc Natl Acad Sci U S A (2016) 0.83
Mechanobiology of platelets: techniques to study the role of fluid flow and platelet retraction forces at the micro- and nano-scale. Int J Mol Sci (2011) 0.83
Angiogenic responses are enhanced in mechanically and microscopically characterized, microbial transglutaminase crosslinked collagen matrices with increased stiffness. Acta Biomater (2013) 0.83
Mechanical impulses can control metaphase progression in a mammalian cell. Proc Natl Acad Sci U S A (2012) 0.83
Mechano-transduction: from molecules to tissues. PLoS Biol (2014) 0.83
The mechanical regulation of integrin-cadherin crosstalk organizes cells, signaling and forces. J Cell Sci (2016) 0.83
A simple force-motion relation for migrating cells revealed by multipole analysis of traction stress. Biophys J (2014) 0.82
Tissue mechanics and adhesion during embryo development. Dev Biol (2014) 0.82
3D Viscoelastic traction force microscopy. Soft Matter (2014) 0.82
Integrated micro/nanoengineered functional biomaterials for cell mechanics and mechanobiology: a materials perspective. Adv Mater (2013) 0.82
Nesprin-2G, a Component of the Nuclear LINC Complex, Is Subject to Myosin-Dependent Tension. Biophys J (2016) 0.81
Cellular mechanisms of skin repair in humans and other mammals. J Cell Commun Signal (2016) 0.81
Spatial distribution of cell-cell and cell-ECM adhesions regulates force balance while main-taining E-cadherin molecular tension in cell pairs. Mol Biol Cell (2015) 0.81
Src, p130Cas, and Mechanotransduction in Cancer Cells. Genes Cancer (2012) 0.81
Synaptopodin couples epithelial contractility to α-actinin-4-dependent junction maturation. J Cell Biol (2015) 0.80
Monitoring developmental force distributions in reconstituted embryonic epithelia. Methods (2015) 0.80
Cell organisation in the colonic crypt: a theoretical comparison of the pedigree and niche concepts. PLoS One (2013) 0.79
On the Quantification of Cellular Velocity Fields. Biophys J (2016) 0.79
Contact inhibition of locomotion and mechanical cross-talk between cell-cell and cell-substrate adhesion determine the pattern of junctional tension in epithelial cell aggregates. Mol Biol Cell (2016) 0.79
NF2/Merlin mediates contact-dependent inhibition of EGFR mobility and internalization via cortical actomyosin. J Cell Biol (2015) 0.79
Mechanisms and in vivo functions of contact inhibition of locomotion. Nat Rev Mol Cell Biol (2016) 0.78
ROCK2 primes the endothelium for vascular hyperpermeability responses by raising baseline junctional tension. Vascul Pharmacol (2015) 0.78
Multicellular architecture of malignant breast epithelia influences mechanics. PLoS One (2014) 0.78
α-Catenin localization and sarcomere self-organization on N-cadherin adhesive patterns are myocyte contractility driven. PLoS One (2012) 0.78
Mean deformation metrics for quantifying 3D cell-matrix interactions without requiring information about matrix material properties. Proc Natl Acad Sci U S A (2016) 0.77
Collective Signal Processing in Cluster Chemotaxis: Roles of Adaptation, Amplification, and Co-attraction in Collective Guidance. PLoS Comput Biol (2016) 0.77
Optical measurement of arterial mechanical properties: from atherosclerotic plaque initiation to rupture. J Biomed Opt (2013) 0.77
Glassy dynamics, cell mechanics, and endothelial permeability. J Phys Chem B (2013) 0.77
Walking the Line: A Fibronectin Fiber-Guided Assay to Probe Early Steps of (Lymph)angiogenesis. PLoS One (2015) 0.77
The interplay of cell-cell and cell-substrate adhesion in collective cell migration. J R Soc Interface (2014) 0.77
Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension. Nat Commun (2016) 0.76
Stage-specific control of stem cell niche architecture in the Drosophila testis by the posterior Hox gene Abd-B. Comput Struct Biotechnol J (2015) 0.76
Engineering cell-cell signaling. Curr Opin Biotechnol (2013) 0.76
Reduced cell cohesiveness of outgrowths from eccrine sweat glands delays wound closure in elderly skin. Aging Cell (2016) 0.76
N-cadherin adhesive interactions modulate matrix mechanosensing and fate commitment of mesenchymal stem cells. Nat Mater (2016) 0.76
E-cadherin and LGN align epithelial cell divisions with tissue tension independently of cell shape. Proc Natl Acad Sci U S A (2017) 0.76
Intracellular forces during guided cell growth on micropatterns using FRET measurement. J Biomech (2015) 0.75
Force transmission in epithelial tissues. Dev Dyn (2016) 0.75
P-cadherin-mediated Rho GTPase regulation during collective cell migration. Small GTPases (2016) 0.75
Illuminating human health through cell mechanics. Swiss Med Wkly (2013) 0.75
Dynamic Imaging Reveals Coordinate Effects of Cyclic Stretch and Substrate Stiffness on Endothelial Integrity. Ann Biomed Eng (2016) 0.75
Conformational plasticity of JRAB/MICAL-L2 provides "law and order" in collective cell migration. Mol Biol Cell (2016) 0.75
Margaret Gardel: at the interface of physics and biology. Interview by Caitlin Sedwick. J Cell Biol (2013) 0.75
Simvastatin Ameliorates Matrix Stiffness-Mediated Endothelial Monolayer Disruption. PLoS One (2016) 0.75
Current status and perspectives in atomic force microscopy-based identification of cellular transformation. Int J Nanomedicine (2016) 0.75
Vitamin C inhibit the proliferation, migration and epithelial-mesenchymal-transition of lens epithelial cells by destabilizing HIF-1α. Int J Clin Exp Med (2015) 0.75
Tissue cells feel and respond to the stiffness of their substrate. Science (2005) 23.42
Tensional homeostasis and the malignant phenotype. Cancer Cell (2005) 19.30
Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell (2009) 14.40
Regulation of cadherin-mediated adhesion in morphogenesis. Nat Rev Mol Cell Biol (2005) 9.27
Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high-resolution tracking of E-cadherin-green fluorescent protein. J Cell Biol (1998) 5.03
Cell prestress. I. Stiffness and prestress are closely associated in adherent contractile cells. Am J Physiol Cell Physiol (2002) 4.81
Forces for morphogenesis investigated with laser microsurgery and quantitative modeling. Science (2003) 4.42
Mechanical integration of actin and adhesion dynamics in cell migration. Annu Rev Cell Dev Biol (2010) 4.06
High resolution traction force microscopy based on experimental and computational advances. Biophys J (2007) 3.89
Localized zones of Rho and Rac activities drive initiation and expansion of epithelial cell-cell adhesion. J Cell Biol (2007) 3.76
Myosin II dynamics are regulated by tension in intercalating cells. Dev Cell (2009) 3.49
Mechanical tugging force regulates the size of cell-cell junctions. Proc Natl Acad Sci U S A (2010) 3.44
Nature and anisotropy of cortical forces orienting Drosophila tissue morphogenesis. Nat Cell Biol (2008) 3.44
Myosin 2 is a key Rho kinase target necessary for the local concentration of E-cadherin at cell-cell contacts. Mol Biol Cell (2005) 3.43
Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II-dependent manner. J Cell Biol (2010) 3.25
Integrin-dependent actomyosin contraction regulates epithelial cell scattering. J Cell Biol (2005) 3.20
Mechanotransduction at cell-matrix and cell-cell contacts. Annu Rev Biomed Eng (2004) 3.15
Substrate rigidity regulates the formation and maintenance of tissues. Biophys J (2005) 3.08
Occluding junctions and cytoskeletal components in a cultured transporting epithelium. J Cell Biol (1980) 3.04
Cell adhesion receptors in mechanotransduction. Curr Opin Cell Biol (2008) 2.56
Cytoskeletal coherence requires myosin-IIA contractility. J Cell Sci (2010) 2.13
Intracellular stress tomography reveals stress focusing and structural anisotropy in cytoskeleton of living cells. Am J Physiol Cell Physiol (2003) 2.09
Strength dependence of cadherin-mediated adhesions. Biophys J (2010) 1.86
Traction forces exerted through N-cadherin contacts. Biol Cell (2006) 1.78
Upregulation of forces and morphogenic asymmetries in dorsal closure during Drosophila development. Biophys J (2007) 1.73
The hard life of soft cells. Cell Motil Cytoskeleton (2009) 1.61
Rigidity-dependent cross talk between integrin and cadherin signaling. Biophys J (2009) 1.26
Biology and physics of cell shape changes in development. Curr Biol (2009) 1.20
High resolution traction force microscopy based on experimental and computational advances. Biophys J (2007) 3.89
Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed. J Cell Biol (2008) 3.44
Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration. Cell (2012) 2.87
Identification and characterization of a small molecule inhibitor of formin-mediated actin assembly. Chem Biol (2009) 2.57
Mechanosensing in actin stress fibers revealed by a close correlation between force and protein localization. J Cell Sci (2009) 2.14
Tension is required but not sufficient for focal adhesion maturation without a stress fiber template. J Cell Biol (2012) 2.12
Transient frictional slip between integrin and the ECM in focal adhesions under myosin II tension. Curr Biol (2010) 2.11
Plasmodium sporozoite motility is modulated by the turnover of discrete adhesion sites. Cell Host Microbe (2009) 2.01
Reconstitution of contractile actomyosin bundles. Biophys J (2011) 1.71
Spatiotemporal constraints on the force-dependent growth of focal adhesions. Biophys J (2011) 1.69
Regulation of cell motile behavior by crosstalk between cadherin- and integrin-mediated adhesions. Proc Natl Acad Sci U S A (2010) 1.68
F-actin buckling coordinates contractility and severing in a biomimetic actomyosin cortex. Proc Natl Acad Sci U S A (2012) 1.65
United we stand: integrating the actin cytoskeleton and cell-matrix adhesions in cellular mechanotransduction. J Cell Sci (2012) 1.63
A zyxin-mediated mechanism for actin stress fiber maintenance and repair. Dev Cell (2010) 1.62
Mechanics of the F-actin cytoskeleton. J Biomech (2009) 1.58
Filamentous network mechanics and active contractility determine cell and tissue shape. Biophys J (2008) 1.44
Dynamic and structural signatures of lamellar actomyosin force generation. Mol Biol Cell (2011) 1.40
Contractile units in disordered actomyosin bundles arise from F-actin buckling. Phys Rev Lett (2012) 1.38
Micropatterned silicone elastomer substrates for high resolution analysis of cellular force patterns. Rev Sci Instrum (2007) 1.32
Preparation of complaint matrices for quantifying cellular contraction. J Vis Exp (2010) 1.31
Optimization of traction force microscopy for micron-sized focal adhesions. J Phys Condens Matter (2010) 1.29
Propagation of mechanical stress through the actin cytoskeleton toward focal adhesions: model and experiment. Biophys J (2007) 1.25
CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling. J Cell Biol (2007) 1.21
Avidity enhancement of L-selectin bonds by flow: shear-promoted rotation of leukocytes turn labile bonds into functional tethers. J Cell Biol (2003) 1.20
Requirements for contractility in disordered cytoskeletal bundles. New J Phys (2012) 1.12
Probing cellular microenvironments and tissue remodeling by atomic force microscopy. Pflugers Arch (2007) 1.10
Assembly kinetics determine the architecture of α-actinin crosslinked F-actin networks. Nat Commun (2012) 1.09
Effect of adhesion geometry and rigidity on cellular force distributions. Phys Rev Lett (2009) 1.07
Thick filament length and isoform composition determine self-organized contractile units in actomyosin bundles. Biophys J (2013) 1.06
Conserved F-actin dynamics and force transmission at cell adhesions. Curr Opin Cell Biol (2010) 1.06
Force localization in contracting cell layers. Phys Rev Lett (2011) 1.02
Stiffness-controlled three-dimensional extracellular matrices for high-resolution imaging of cell behavior. Nat Protoc (2012) 0.99
Bistability of cell-matrix adhesions resulting from nonlinear receptor-ligand dynamics. Biophys J (2006) 0.98
Endothelial barrier disruption and recovery is controlled by substrate stiffness. Microvasc Res (2013) 0.97
Two competing orientation patterns explain experimentally observed anomalies in growing actin networks. Proc Natl Acad Sci U S A (2010) 0.94
Stochastic dynamics of adhesion clusters under shared constant force and with rebinding. J Chem Phys (2004) 0.94
A quantitative measure for alterations in the actin cytoskeleton investigated with automated high-throughput microscopy. Cytometry A (2010) 0.94
Polarizing cytoskeletal tension to induce leader cell formation during collective cell migration. Biointerphases (2013) 0.94
Myosin II-mediated focal adhesion maturation is tension insensitive. PLoS One (2013) 0.93
Self-organization of myosin II in reconstituted actomyosin bundles. Biophys J (2012) 0.92
Environmental constraints guide migration of malaria parasites during transmission. PLoS Pathog (2011) 0.91
Modeling cytoskeletal flow over adhesion sites: competition between stochastic bond dynamics and intracellular relaxation. J Phys Condens Matter (2010) 0.91
Stochastic force generation by small ensembles of myosin II motors. Phys Rev Lett (2012) 0.91
Reconstructing the orientation distribution of actin filaments in the lamellipodium of migrating keratocytes from electron microscopy tomography data. Cytometry A (2012) 0.90
Stochastic simulations of cargo transport by processive molecular motors. J Chem Phys (2009) 0.89
L-selectin dimerization enhances tether formation to properly spaced ligand. J Biol Chem (2002) 0.89
Distribution of directional change as a signature of complex dynamics. Proc Natl Acad Sci U S A (2013) 0.86
A kinetic model for RNA-interference of focal adhesions. BMC Syst Biol (2013) 0.85
Role of anisotropy for protein-protein encounter. Phys Rev E Stat Nonlin Soft Matter Phys (2010) 0.85
Biophysics. Clutch dynamics. Science (2008) 0.85
Attenuation of lipopolysaccharide-induced lung vascular stiffening by lipoxin reduces lung inflammation. Am J Respir Cell Mol Biol (2015) 0.83
Dynamic ordering of nuclei in syncytial embryos: a quantitative analysis of the role of cytoskeletal networks. Integr Biol (Camb) (2011) 0.83
Shear thickening of F-actin networks crosslinked with non-muscle myosin IIB. Soft Matter (2011) 0.82
Viscoelastic response of contractile filament bundles. Phys Rev E Stat Nonlin Soft Matter Phys (2011) 0.82
Hysteresis in the cell response to time-dependent substrate stiffness. Biophys J (2010) 0.82
Actin assembly factors regulate the gelation kinetics and architecture of F-actin networks. Biophys J (2013) 0.81
Oscillations of Min-proteins in micropatterned environments: a three-dimensional particle-based stochastic simulation approach. Soft Matter (2014) 0.81
Dynamics of protein-protein encounter: a Langevin equation approach with reaction patches. J Chem Phys (2008) 0.80
Cellular mechanosensing: Sharing the force. Nat Mater (2013) 0.79
Unifying autocatalytic and zeroth-order branching models for growing actin networks. Phys Rev E Stat Nonlin Soft Matter Phys (2013) 0.78
Stochastic dynamics of small ensembles of non-processive molecular motors: the parallel cluster model. J Chem Phys (2013) 0.78
Observation and characterization of the vestige of the jamming transition in a thermal three-dimensional system. Phys Rev E Stat Nonlin Soft Matter Phys (2013) 0.77
Optimizing micropattern geometries for cell shape and migration with genetic algorithms. Integr Biol (Camb) (2016) 0.77
Collective effects in cellular structure formation mediated by compliant environments: a Monte Carlo study. Acta Biomater (2006) 0.77
Role of dynamic capsomere supply for viral capsid self-assembly. Phys Biol (2015) 0.76
Membrane and actin reorganization in electropulse-induced cell fusion. J Cell Sci (2013) 0.76
Calcium oscillations in wounded fibroblast monolayers are spatially regulated through substrate mechanics. Phys Biol (2017) 0.75