LRIT3 is essential to localize TRPM1 to the dendritic tips of depolarizing bipolar cells and may play a role in cone synapse formation.

PubWeight™: 0.79‹?›

🔗 View Article (PMID 25997951)

Published in Eur J Neurosci on July 04, 2015

Authors

Marion Neuillé1,2,3, Catherine W Morgans4, Yan Cao5, Elise Orhan1,2,3, Christelle Michiels1,2,3, José-Alain Sahel1,2,3,6,7,8,9, Isabelle Audo1,2,3,6,7, Robert M Duvoisin4, Kirill A Martemyanov5, Christina Zeitz1,2,3

Author Affiliations

1: INSERM, U968, Paris, F-75012, France.
2: CNRS, UMR_7210, Paris, F-75012, France.
3: Sorbonne Universités, UPMC Univ Paris 06, UMR_S 968, Institut de la Vision, Paris, F-75012, France.
4: Department of Physiology & Pharmacology, Oregon Health & Science University, Portland, OR, 97239, USA.
5: Department of Neuroscience, The Scripps Research Institute, Jupiter, FL, 33458, USA.
6: Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, DHU ViewMaintain, INSERM-DHOS CIC, 1423, Paris, F-75012, France.
7: Institute of Ophthalmology, University College of London, London, EC1V 9EL, UK.
8: Fondation Ophtalmologique Adolphe de Rothschild, Paris, F-75019, France.
9: Académie des Sciences-Institut de France, Paris, F-75006, France.

Articles cited by this

Immunocytochemical analysis of the mouse retina. J Comp Neurol (2000) 3.95

RIBEYE, a component of synaptic ribbons: a protein's journey through evolution provides insight into synaptic ribbon function. Neuron (2000) 3.21

Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene. Cell (1995) 2.81

Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate. J Biol Chem (1993) 2.80

Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of the ribbon complex. J Cell Biol (2005) 2.48

A transient receptor potential-like channel mediates synaptic transmission in rod bipolar cells. J Neurosci (2009) 2.35

TRPM1 is required for the depolarizing light response in retinal ON-bipolar cells. Proc Natl Acad Sci U S A (2009) 2.27

Instability of GGL domain-containing RGS proteins in mice lacking the G protein beta-subunit Gbeta5. Proc Natl Acad Sci U S A (2003) 2.25

Organization and dynamics of PDZ-domain-related supramodules in the postsynaptic density. Nat Rev Neurosci (2009) 2.22

TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade. Proc Natl Acad Sci U S A (2009) 2.20

Developmentally regulated postsynaptic localization of a metabotropic glutamate receptor in rat rod bipolar cells. Cell (1994) 2.20

The light response of ON bipolar neurons requires G[alpha]o. J Neurosci (2000) 2.19

Rod bipolar cells in the mammalian retina show protein kinase C-like immunoreactivity. J Comp Neurol (1990) 1.90

A naturally occurring mouse model of X-linked congenital stationary night blindness. Invest Ophthalmol Vis Sci (1998) 1.76

The metabotropic receptor mGluR6 may signal through G(o), but not phosphodiesterase, in retinal bipolar cells. J Neurosci (1999) 1.66

Gbeta5 is required for normal light responses and morphology of retinal ON-bipolar cells. J Neurosci (2007) 1.60

Specific binding of peanut lectin to a class of retinal photoreceptor cells. A species comparison. Invest Ophthalmol Vis Sci (1984) 1.53

Selective lectin binding of the developing mouse retina. J Comp Neurol (1983) 1.52

Identification of the gene and the mutation responsible for the mouse nob phenotype. Invest Ophthalmol Vis Sci (2003) 1.47

Localization of nyctalopin in the mammalian retina. Eur J Neurosci (2006) 1.44

Retina-specific GTPase accelerator RGS11/G beta 5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons. J Neurosci (2009) 1.38

Allelic variance between GRM6 mutants, Grm6nob3 and Grm6nob4 results in differences in retinal ganglion cell visual responses. J Physiol (2008) 1.36

GPR179 is required for depolarizing bipolar cell function and is mutated in autosomal-recessive complete congenital stationary night blindness. Am J Hum Genet (2012) 1.33

Dopamine cells and rod bipolar cells contain protein kinase C-like immunoreactivity in some vertebrate retinas. Neurosci Lett (1988) 1.32

Gbeta5-RGS complexes co-localize with mGluR6 in retinal ON-bipolar cells. Eur J Neurosci (2007) 1.32

Alpha subunit of Go localizes in the dendritic tips of ON bipolar cells. J Comp Neurol (1998) 1.29

Generation, identification and functional characterization of the nob4 mutation of Grm6 in the mouse. Vis Neurosci (2007) 1.27

Regulators of G protein signaling RGS7 and RGS11 determine the onset of the light response in ON bipolar neurons. Proc Natl Acad Sci U S A (2012) 1.26

Targeting of RGS7/Gbeta5 to the dendritic tips of ON-bipolar cells is independent of its association with membrane anchor R7BP. J Neurosci (2008) 1.26

A role for nyctalopin, a small leucine-rich repeat protein, in localizing the TRP melastatin 1 channel to retinal depolarizing bipolar cell dendrites. J Neurosci (2011) 1.24

Congenital stationary night blindness: an analysis and update of genotype-phenotype correlations and pathogenic mechanisms. Prog Retin Eye Res (2014) 1.19

Whole-exome sequencing identifies LRIT3 mutations as a cause of autosomal-recessive complete congenital stationary night blindness. Am J Hum Genet (2012) 1.18

TRPM1 forms complexes with nyctalopin in vivo and accumulates in postsynaptic compartment of ON-bipolar neurons in mGluR6-dependent manner. J Neurosci (2011) 1.17

GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes. J Cell Biol (2012) 1.06

Depolarizing bipolar cell dysfunction due to a Trpm1 point mutation. J Neurophysiol (2012) 1.05

Neurochemical organization of the first visual synapse. Keio J Med (2002) 1.04

mGluR6 deletion renders the TRPM1 channel in retina inactive. J Neurophysiol (2011) 1.00

R9AP stabilizes RGS11-G beta5 and accelerates the early light response of ON-bipolar cells. Vis Neurosci (2010) 0.95

Differential function of Gγ13 in rod bipolar and ON cone bipolar cells. J Physiol (2015) 0.93

Nyctalopin is essential for synaptic transmission in the cone dominated zebrafish retina. Eur J Neurosci (2006) 0.90

Ectopic synaptic ribbons in dendrites of mouse retinal ON- and OFF-bipolar cells. Cell Tissue Res (2009) 0.89

Lrit3 deficient mouse (nob6): a novel model of complete congenital stationary night blindness (cCSNB). PLoS One (2014) 0.89

GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells. J Neurosci (2014) 0.88

Orphan receptor GPR179 forms macromolecular complexes with components of metabotropic signaling cascade in retina ON-bipolar neurons. Invest Ophthalmol Vis Sci (2013) 0.85

Serum TRPM1 autoantibodies from melanoma associated retinopathy patients enter retinal on-bipolar cells and attenuate the electroretinogram in mice. PLoS One (2013) 0.83

Further insights into GPR179: expression, localization, and associated pathogenic mechanisms leading to complete congenital stationary night blindness. Invest Ophthalmol Vis Sci (2013) 0.81

Effects of mGluR6-deficiency on photoreceptor ribbon synapse formation: comparison of electron microscopic analysis of serial sections with random sections. Vis Neurosci (2014) 0.81

Immunolocalization of X-arrestin in human cone photoreceptors. FEBS Lett (1996) 0.81

Differential binding characteristics and applications of DGal beta 1----3DGalNAc specific lectins. Mol Cell Biochem (1984) 0.79

Articles by these authors

All ON pathways are not alike. J Physiol (2015) 0.75