The Th17 axis in psoriatic disease: pathogenetic and therapeutic implications.

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🔗 View Article (PMC 4389010)

Published in Auto Immun Highlights on January 22, 2014

Authors

Beatrice Marinoni1, Angela Ceribelli1, Marco S Massarotti2, Carlo Selmi3

Author Affiliations

1: Division of Rheumatology and Clinical Immunology, Humanitas Clinical and Research Center, Rozzano, Milan Italy ; Biometra Department, University of Milan, Milan, Italy.
2: Division of Rheumatology and Clinical Immunology, Humanitas Clinical and Research Center, Rozzano, Milan Italy.
3: Division of Rheumatology and Clinical Immunology, Humanitas Clinical and Research Center, Rozzano, Milan Italy ; Biometra Department, University of Milan, Milan, Italy ; Division of Rheumatology, Allergy and Clinical Immunology, Genome and Biomedical Sciences Facility, University of California at Davis School of Medicine, 451 Health Sciences Drive, Suite 6510, Davis, CA 95616 USA.

Associated clinical trials:

A Phase 3 Study in Participants With Moderate to Severe Psoriasis (UNCOVER-2) (UNCOVER-2) | NCT01597245

A Study in Participants With Moderate to Severe Psoriasis (UNCOVER-3) (UNCOVER-3) | NCT01646177

Study of Efficacy and Safety of Brodalumab Compared With Placebo and Ustekinumab in Moderate to Severe Plaque Psoriasis Subjects (AMAGINE-2) | NCT01708603

Study of Efficacy, Safety, and Withdrawal and Retreatment With Brodalumab (AMG 827) in Moderate to Severe Plaque Psoriasis Subjects (AMAGINE-1) | NCT01708590

Study of Efficacy and Safety of Brodalumab Compared With Placebo and Ustekinumab in Moderate to Severe Plaque Psoriasis Subjects (AMAGINE-3) | NCT01708629

A Study of Ixekizumab in Participants With Active Psoriatic Arthritis (SPIRIT-P1) | NCT01695239

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