Published in J Immunol on May 27, 2015
Response to interferons and antibacterial innate immunity in the absence of tyrosine-phosphorylated STAT1. EMBO Rep (2016) 0.81
Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses. PLoS Pathog (2015) 0.79
Type I interferon-regulated gene expression and signaling in murine mixed glial cells lacking signal transducers and activators of transcription 1 or 2 or interferon regulatory factor 9. J Biol Chem (2017) 0.75
STAT2-directed pathogen responses. Oncotarget (2015) 0.75
STAT1 is essential for the inhibition of hepatitis C virus replication by interferon-λ but not by interferon-α. Sci Rep (2016) 0.75
Impact of host genetic polymorphisms on vaccine induced antibody response. Hum Vaccin Immunother (2016) 0.75
Canonical and Non-Canonical Aspects of JAK-STAT Signaling: Lessons from Interferons for Cytokine Responses. Front Immunol (2017) 0.75
Integrity of a HPV11 infection cell model and identification of (-)-Epigallocatechin-3-gallate as a potential HPV11 inhibitor. Oncotarget (2016) 0.75
A diverse range of gene products are effectors of the type I interferon antiviral response. Nature (2011) 12.86
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell (1996) 10.49
Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell (1996) 10.44
Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science (1992) 6.09
Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha. Proc Natl Acad Sci U S A (1992) 5.50
JAK-STAT signaling: from interferons to cytokines. J Biol Chem (2007) 5.28
Tracking STAT nuclear traffic. Nat Rev Immunol (2006) 2.99
Selective immortalization of murine macrophages from fresh bone marrow by a raf/myc recombinant murine retrovirus. Nature (1986) 2.64
Immune response in Stat2 knockout mice. Immunity (2000) 2.37
Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-alpha/beta, IFN-gamma, and IFN-lambda in host defense. Immunol Rev (2008) 2.35
Constitutive type I interferon modulates homeostatic balance through tonic signaling. Immunity (2012) 2.23
Interferon-inducible effector mechanisms in cell-autonomous immunity. Nat Rev Immunol (2012) 2.21
The two faces of interferon-γ in cancer. Clin Cancer Res (2011) 2.20
Viral tricks to grid-lock the type I interferon system. Curr Opin Microbiol (2010) 2.17
Partial impairment of cytokine responses in Tyk2-deficient mice. Immunity (2000) 2.17
Interferome v2.0: an updated database of annotated interferon-regulated genes. Nucleic Acids Res (2012) 2.08
Viruses evade the immune system through type I interferon-mediated STAT2-dependent, but STAT1-independent, signaling. Immunity (2005) 2.00
The Icm/Dot type-IV secretion systems of Legionella pneumophila and Coxiella burnetii. FEMS Microbiol Rev (2005) 1.93
Nonconventional initiation complex assembly by STAT and NF-kappaB transcription factors regulates nitric oxide synthase expression. Immunity (2010) 1.90
Essential and non-redundant roles of p48 (ISGF3 gamma) and IRF-1 in both type I and type II interferon responses, as revealed by gene targeting studies. Genes Cells (1996) 1.86
Critical roles for both STAT1-dependent and STAT1-independent pathways in the control of primary dengue virus infection in mice. J Immunol (2005) 1.79
Restriction of Legionella pneumophila growth in macrophages requires the concerted action of cytokine and Naip5/Ipaf signalling pathways. Cell Microbiol (2007) 1.65
STAT2 mediates innate immunity to Dengue virus in the absence of STAT1 via the type I interferon receptor. PLoS Pathog (2011) 1.54
A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses. Nature (2012) 1.44
STAT1-independent cell type-specific regulation of antiviral APOBEC3G by IFN-alpha. J Immunol (2006) 1.25
Paramyxovirus disruption of interferon signal transduction: STATus report. J Interferon Cytokine Res (2009) 1.21
Stat2 is a transcriptional activator that requires sequence-specific contacts provided by stat1 and p48 for stable interaction with DNA. J Biol Chem (1997) 1.20
Interferons direct an effective innate response to Legionella pneumophila infection. J Biol Chem (2009) 1.19
IRF-9/STAT2 [corrected] functional interaction drives retinoic acid-induced gene G expression independently of STAT1. Cancer Res (2009) 1.18
Suppressor of cytokine signaling (SOCS) 1 inhibits type I interferon (IFN) signaling via the interferon alpha receptor (IFNAR1)-associated tyrosine kinase Tyk2. J Biol Chem (2011) 1.17
Regulation of cytokine signaling by the SOCS and Spred family proteins. Keio J Med (2009) 1.16
Dysregulated Sonic hedgehog signaling and medulloblastoma consequent to IFN-alpha-stimulated STAT2-independent production of IFN-gamma in the brain. J Clin Invest (2003) 1.16
Organization of the mouse RNA-specific adenosine deaminase Adar1 gene 5'-region and demonstration of STAT1-independent, STAT2-dependent transcriptional activation by interferon. Virology (2008) 1.12
Stat1 and SUMO modification. Blood (2006) 1.12
Stat2-dependent regulation of MHC class II expression. J Immunol (2007) 1.04
Clinical outcomes for hospitalized patients with Legionella pneumonia in the antigenuria era: the influence of levofloxacin therapy. Clin Infect Dis (2005) 0.99
Cellular microbiology and molecular ecology of Legionella-amoeba interaction. Virulence (2013) 0.99
Immunology taught by bacteria. J Clin Immunol (2010) 0.98
A conserved IFN-alpha receptor tyrosine motif directs the biological response to type I IFNs. J Immunol (2008) 0.96
IFNβ/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH oxidase-mediated airway antiviral response. Cell Res (2013) 0.90
Pooled shRNA screenings: experimental approach. Methods Mol Biol (2013) 0.88
STAT2: A shape-shifting anti-viral super STAT. JAKSTAT (2013) 0.86
Protein tyrosine phosphatases as wardens of STAT signaling. JAKSTAT (2014) 0.80
Interferon-gamma reverses the evasion of Birc1e/Naip5 gene mediated murine macrophage immunity by Legionella pneumophila mutant lacking flagellin. Microbiol Immunol (2007) 0.79