Published in Antioxid Redox Signal on August 10, 2015
Absolute and Relative Activity Values in Assessing the Effect of NADPH Oxidase Inhibitors. Antioxid Redox Signal (2015) 1.08
Mitigation of NADPH Oxidase 2 Activity as a Strategy to Inhibit Peroxynitrite Formation. J Biol Chem (2016) 0.83
Anti-Inflammatory Small Molecules To Treat Seizures and Epilepsy: From Bench to Bedside. Trends Pharmacol Sci (2016) 0.83
Pharmacology and Clinical Drug Candidates in Redox Medicine. Antioxid Redox Signal (2015) 0.79
NADPH oxidase in brain injury and neurodegenerative disorders. Mol Neurodegener (2017) 0.78
European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS). Redox Biol (2017) 0.77
NOX Activation by Subunit Interaction and Underlying Mechanisms in Disease. Front Cell Neurosci (2017) 0.75
Response to Pick. Antioxid Redox Signal (2015) 0.75
Recent Developments in the Probes and Assays for Measurement of the Activity of NADPH Oxidases. Cell Biochem Biophys (2017) 0.75
The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev (2007) 21.13
Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury. Cell (2008) 6.37
Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant. Hypertension (2007) 5.80
The effect of the inhibitor diphenylene iodonium on the superoxide-generating system of neutrophils. Specific labelling of a component polypeptide of the oxidase. Biochem J (1986) 4.35
NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation. Biochem J (2007) 3.88
Nox enzymes, ROS, and chronic disease: an example of antagonistic pleiotropy. Free Radic Biol Med (2007) 3.48
Regulation of Nox and Duox enzymatic activity and expression. Free Radic Biol Med (2007) 3.44
Studies on the inhibitory mechanism of iodonium compounds with special reference to neutrophil NADPH oxidase. Biochem J (1993) 3.12
p47phox is required for atherosclerotic lesion progression in ApoE(-/-) mice. J Clin Invest (2001) 3.02
Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney. J Biol Chem (2005) 2.98
NADPH oxidases in the kidney. Antioxid Redox Signal (2006) 2.70
Oxidative innate immune defenses by Nox/Duox family NADPH oxidases. Contrib Microbiol (2008) 2.50
Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitis. Gastroenterology (2002) 2.45
Molecular evolution of the reactive oxygen-generating NADPH oxidase (Nox/Duox) family of enzymes. BMC Evol Biol (2007) 2.29
Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE-/- mice. Am J Physiol Heart Circ Physiol (2009) 2.00
Effects of phorbol myristate acetate on the metabolism and ultrastructure of neutrophils in chronic granulomatous disease. J Clin Invest (1974) 1.92
The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice. Proc Natl Acad Sci U S A (2006) 1.90
Genesis and development of DPPH method of antioxidant assay. J Food Sci Technol (2011) 1.89
Characterization of a new human diploid myeloid leukemia cell line (PLB-985) with granulocytic and monocytic differentiating capacity. Blood (1987) 1.87
Superoxide produced by activated neutrophils efficiently reduces the tetrazolium salt, WST-1 to produce a soluble formazan: a simple colorimetric assay for measuring respiratory burst activation and for screening anti-inflammatory agents. J Immunol Methods (2000) 1.81
Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets. Antioxid Redox Signal (2009) 1.80
A key role for NOX4 in epithelial cell death during development of lung fibrosis. Antioxid Redox Signal (2011) 1.79
Apocynin: molecular aptitudes. Mediators Inflamm (2008) 1.77
Neutrophil signal transduction and activation of the respiratory burst. Physiol Rev (1993) 1.69
Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice. J Clin Invest (2009) 1.68
Metabolic activation of natural phenols into selective oxidative burst agonists by activated human neutrophils. Free Radic Biol Med (1990) 1.68
Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits. Chem Biol (2012) 1.60
Gene targeting of X chromosome-linked chronic granulomatous disease locus in a human myeloid leukemia cell line and rescue by expression of recombinant gp91phox. Proc Natl Acad Sci U S A (1993) 1.60
Apocynin improves outcome in experimental stroke with a narrow dose range. Neuroscience (2008) 1.59
NADPH oxidases in the vasculature: molecular features, roles in disease and pharmacological inhibition. Pharmacol Ther (2008) 1.58
Role of NADPH oxidase in retinal vascular inflammation. Invest Ophthalmol Vis Sci (2008) 1.57
Isolation of human neutrophils from venous blood. Methods Mol Biol (2007) 1.49
The NOX toolbox: validating the role of NADPH oxidases in physiology and disease. Cell Mol Life Sci (2012) 1.44
Celastrol protects against MPTP- and 3-nitropropionic acid-induced neurotoxicity. J Neurochem (2005) 1.44
Methods for defining distinct bioenergetic profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human blood. Lab Invest (2013) 1.41
Nox enzymes and new thinking on reactive oxygen: a double-edged sword revisited. Annu Rev Pathol (2013) 1.38
Involvement of phenyl radicals in iodonium inhibition of flavoenzymes. Mol Pharmacol (1994) 1.30
A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells. ACS Chem Biol (2010) 1.26
Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement. Antioxid Redox Signal (2014) 1.23
Celastrol blocks neuronal cell death and extends life in transgenic mouse model of amyotrophic lateral sclerosis. Neurodegener Dis (2005) 1.23
Methods for detection of mitochondrial and cellular reactive oxygen species. Antioxid Redox Signal (2012) 1.20
Suramin: a novel antineoplastic agent with multiple potential mechanisms of action. Cancer Res (1993) 1.15
A phosphoprotein of Mr 47,000, defective in autosomal chronic granulomatous disease, copurifies with one of two soluble components required for NADPH:O2 oxidoreductase activity in human neutrophils. J Clin Invest (1989) 1.14
Systemic infusion of naloxone reduces degeneration of rat substantia nigral dopaminergic neurons induced by intranigral injection of lipopolysaccharide. J Pharmacol Exp Ther (2000) 1.14
Anti-invasive adjuvant therapy with imipramine blue enhances chemotherapeutic efficacy against glioma. Sci Transl Med (2012) 1.12
Role for Nox1 NADPH oxidase in atherosclerosis. Atherosclerosis (2011) 1.11
New insights on NOX enzymes in the central nervous system. Antioxid Redox Signal (2014) 1.06
Complete and reversible inhibition of NADPH oxidase in human neutrophils by phenylarsine oxide at a step distal to membrane translocation of the enzyme subunits. J Biol Chem (1995) 1.05
Fungal gliotoxin targets the onset of superoxide-generating NADPH oxidase of human neutrophils. Biochem Biophys Res Commun (2000) 1.00
Naloxone inhibits immune cell function by suppressing superoxide production through a direct interaction with gp91phox subunit of NADPH oxidase. J Neuroinflammation (2012) 0.97
NADPH oxidase inhibitors: a decade of discovery from Nox2ds to HTS. Cell Mol Life Sci (2012) 0.96
Detection of reactive oxygen species derived from the family of NOX NADPH oxidases. Free Radic Biol Med (2012) 0.96
NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action. Br J Pharmacol (2011) 0.92
High glucose-suppressed endothelin-1 Ca2+ signaling via NADPH oxidase and diacylglycerol-sensitive protein kinase C isozymes in mesangial cells. J Biol Chem (2003) 0.92
Modulation of NADPH oxidase activation in cerebral ischemia/reperfusion injury in rats. Brain Res (2010) 0.90
The effects of oxotremorine, epibatidine, atropine, mecamylamine and naloxone in the tail-flick, hot-plate, and formalin tests in the naked mole-rat (Heterocephalus glaber). In Vivo (2014) 0.87
Some aspects of the pharmacology of diphenyleneiodonium, a bivalent iodine compound. Xenobiotica (1979) 0.87
Gene expression in mammalian cells using BacMam, a modified baculovirus system. Methods Mol Biol (2007) 0.87
On the use of L-012, a luminol-based chemiluminescent probe, for detecting superoxide and identifying inhibitors of NADPH oxidase: a reevaluation. Free Radic Biol Med (2013) 0.86
Is cardiac hypertrophy in spontaneously hypertensive rats the cause or the consequence of oxidative stress? Hypertens Res (2008) 0.85
Apocynin ameliorates cadmium-induced hypertension through elevation of endothelium nitric oxide synthase. Cardiovasc Toxicol (2013) 0.84
Apocynin attenuates pressure overload-induced cardiac hypertrophy in rats by reducing levels of reactive oxygen species. Can J Physiol Pharmacol (2010) 0.84
A subset of N-substituted phenothiazines inhibits NADPH oxidases. Free Radic Biol Med (2015) 0.83
NADPH oxidase-dependent and -independent mechanisms of reported inhibitors of reactive oxygen generation. J Enzyme Inhib Med Chem (2011) 0.82
Celastrol ameliorates murine colitis via modulating oxidative stress, inflammatory cytokines and intestinal homeostasis. Chem Biol Interact (2013) 0.81
Redox active molecules cytochrome c and vitamin C enhance heme-enzyme peroxidations by serving as non-specific agents for redox relay. Biochem Biophys Res Commun (2012) 0.81
NOX2 As a Target for Drug Development: Indications, Possible Complications, and Progress. Antioxid Redox Signal (2014) 0.81
Tephrosia sinapou ethyl acetate extract inhibits inflammatory pain in mice: opioid receptor dependent inhibition of TNFα and IL-1β production. Pharm Biol (2013) 0.81
The dehydrogenase region of the NADPH oxidase component Nox2 acts as a protein disulfide isomerase (PDI) resembling PDIA3 with a role in the binding of the activator protein p67 (phox.). Front Chem (2015) 0.79