Published in Cell Physiol Biochem on January 01, 2015
Chronic signaling via the metabolic checkpoint kinase mTORC1 induces macrophage granuloma formation and marks sarcoidosis progression. Nat Immunol (2017) 1.52
Regulation of innate immune cell function by mTOR. Nat Rev Immunol (2015) 1.27
mTORC2 signalling regulates M2 macrophage differentiation in response to helminth infection and adaptive thermogenesis. Nat Commun (2017) 0.75
A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature (2006) 11.86
Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1. Nat Med (2002) 5.50
Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis. Nat Med (2003) 4.69
The cells and logic for mammalian sour taste detection. Nature (2006) 4.65
Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells. Cell Res (2009) 3.44
Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3beta and its upstream regulators. Cell (2005) 3.42
Randomized phase III trial of induction chemotherapy with docetaxel, cisplatin, and fluorouracil followed by surgery versus up-front surgery in locally advanced resectable oral squamous cell carcinoma. J Clin Oncol (2012) 3.08
The exocyst complex in polarized exocytosis. Curr Opin Cell Biol (2009) 3.04
A policy-driven large scale ecological restoration: quantifying ecosystem services changes in the Loess Plateau of China. PLoS One (2012) 3.00
Coordination of Rab8 and Rab11 in primary ciliogenesis. Proc Natl Acad Sci U S A (2010) 2.88
HIV prevalence in China: integration of surveillance data and a systematic review. Lancet Infect Dis (2013) 2.82
A chronic inflammatory response dominates the skeletal muscle molecular signature in dystrophin-deficient mdx mice. Hum Mol Genet (2002) 2.80
An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition. EMBO J (2010) 2.42
Antiretroviral therapy to prevent HIV transmission in serodiscordant couples in China (2003-11): a national observational cohort study. Lancet (2012) 2.41
The exocyst complex in polarized exocytosis. Int Rev Cytol (2004) 2.40
Genome sequencing and comparative transcriptomics of the model entomopathogenic fungi Metarhizium anisopliae and M. acridum. PLoS Genet (2011) 2.35
In vitro derivation of functional insulin-producing cells from human embryonic stem cells. Cell Res (2007) 2.28
Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer. Genome Res (2012) 2.27
EcR isoforms in Drosophila: testing tissue-specific requirements by targeted blockade and rescue. Development (2003) 2.26
Detection of sequence-specific tyrosine nitration of manganese SOD and SERCA in cardiovascular disease and aging. Am J Physiol Heart Circ Physiol (2006) 2.19
Downregulation of XIAP and induction of apoptosis by the synthetic cyclin-dependent kinase inhibitor GW8510 in non-small cell lung cancer cells. Cancer Biol Ther (2006) 2.13
Superiority of 6-[18F]-fluorodopamine positron emission tomography versus [131I]-metaiodobenzylguanidine scintigraphy in the localization of metastatic pheochromocytoma. J Clin Endocrinol Metab (2003) 2.08
Exo70 interacts with phospholipids and mediates the targeting of the exocyst to the plasma membrane. EMBO J (2007) 2.03
Membrane association and functional regulation of Sec3 by phospholipids and Cdc42. J Cell Biol (2008) 1.99
Estimating the number of people living with HIV/AIDS in China: 2003-09. Int J Epidemiol (2010) 1.96
Complementary roles for biomarkers of biomechanical strain ST2 and N-terminal prohormone B-type natriuretic peptide in patients with ST-elevation myocardial infarction. Circulation (2008) 1.95
A multicenter phase II study of ganetespib monotherapy in patients with genotypically defined advanced non-small cell lung cancer. Clin Cancer Res (2013) 1.90
Highly enantioselective cyanosilylation of aldehydes catalyzed by novel beta-amino alcohol-titanium complexes. J Org Chem (2004) 1.89
High level of AKT activity is associated with resistance to MEK inhibitor AZD6244 (ARRY-142886). Cancer Biol Ther (2009) 1.86
Water-insoluble silk films with silk I structure. Acta Biomater (2009) 1.85
Optical virtual imaging at 50 nm lateral resolution with a white-light nanoscope. Nat Commun (2011) 1.85
Circulating stem cell-like epithelial cell adhesion molecule-positive tumor cells indicate poor prognosis of hepatocellular carcinoma after curative resection. Hepatology (2013) 1.84
A comparison of chemoembolization combination with and without radiotherapy for unresectable hepatocellular carcinoma. Cancer J (2004) 1.84
Phosphatidylinositol 4,5-bisphosphate mediates the targeting of the exocyst to the plasma membrane for exocytosis in mammalian cells. Mol Biol Cell (2007) 1.77
Both CXCR3 and CXCL10/IFN-inducible protein 10 are required for resistance to primary infection by dengue virus. J Immunol (2006) 1.70
Exo70 interacts with the Arp2/3 complex and regulates cell migration. Nat Cell Biol (2006) 1.70
The exocyst protein Sec10 is necessary for primary ciliogenesis and cystogenesis in vitro. Mol Biol Cell (2009) 1.68
CCR6 is required for IL-23-induced psoriasis-like inflammation in mice. J Clin Invest (2009) 1.65
Consideration of the role of radiotherapy for unresectable intrahepatic cholangiocarcinoma: a retrospective analysis of 75 patients. Cancer J (2006) 1.65
Differential expression of the RANKL/RANK/OPG system is associated with bone metastasis in human non-small cell lung cancer. PLoS One (2013) 1.64
Supraspinal glial-neuronal interactions contribute to descending pain facilitation. J Neurosci (2008) 1.61
Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes. Mol Cell Biol (2006) 1.61
Enhancing TRAIL-induced apoptosis by Bcl-X(L) siRNA. Cancer Biol Ther (2005) 1.61
Catalytic asymmetric bromoamination of chalcones: highly efficient synthesis of chiral alpha-bromo-beta-amino ketone derivatives. Angew Chem Int Ed Engl (2010) 1.60
Silk nanospheres and microspheres from silk/pva blend films for drug delivery. Biomaterials (2009) 1.59
Th17 immunity in patients with allergic asthma. Int Arch Allergy Immunol (2009) 1.58
Ras family therapy: Rab, Rho and Ral talk to the exocyst. Trends Cell Biol (2002) 1.57
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. Am J Hum Genet (2013) 1.55
Identification of miRs-143 and -145 that is associated with bone metastasis of prostate cancer and involved in the regulation of EMT. PLoS One (2011) 1.55
Open and endovascular repair of primary mycotic aortic aneurysms: a 10-year single-center experience. J Endovasc Ther (2013) 1.51
Prognostic significance of cyclooxygenase-2 in osteosarcoma: a meta-analysis. Tumour Biol (2013) 1.49
Brominated flame retardants, polychlorinated biphenyls, and organochlorine pesticides in captive giant panda (ailuropoda melanoleuca) and red panda (Ailurus fulgens) from China. Environ Sci Technol (2008) 1.48
Identification of a transiently exposed VE-cadherin epitope that allows for specific targeting of an antibody to the tumor neovasculature. Blood (2005) 1.48
Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis. J Cell Biol (2005) 1.47
The exocyst localizes to the primary cilium in MDCK cells. Biochem Biophys Res Commun (2004) 1.47
miR-1303 targets claudin-18 gene to modulate proliferation and invasion of gastric cancer cells. Dig Dis Sci (2014) 1.46
Vitamin C modulates TET1 function during somatic cell reprogramming. Nat Genet (2013) 1.45
A monoclonal antibody to vascular endothelial-cadherin inhibits tumor angiogenesis without side effects on endothelial permeability. Blood (2002) 1.45
Signaling, polyubiquitination, trafficking, and inclusions: sequestosome 1/p62's role in neurodegenerative disease. J Biomed Biotechnol (2006) 1.44
Feasibility of magnetic resonance imaging-guided high intensity focused ultrasound therapy for ablating uterine fibroids in patients with bowel lies anterior to uterus. Eur J Radiol (2008) 1.43
Mitotic phosphorylation of Exo84 disrupts exocyst assembly and arrests cell growth. J Cell Biol (2013) 1.43
Cyclical regulation of the exocyst and cell polarity determinants for polarized cell growth. Mol Biol Cell (2005) 1.42
Genome sequence of the insect pathogenic fungus Cordyceps militaris, a valued traditional Chinese medicine. Genome Biol (2011) 1.42
Circulating MicroRNA-146a and MicroRNA-21 Predict Left Ventricular Remodeling after ST-Elevation Myocardial Infarction. Cardiology (2015) 1.41
SCM-198 attenuates early atherosclerotic lesions in hypercholesterolemic rabbits via modulation of the inflammatory and oxidative stress pathways. Atherosclerosis (2012) 1.41
Helicobacter pylori infection may improve the survival of patients with carcinomas. Med Hypotheses (2007) 1.40
Postoperative thoracic empyema might improve the survival of patients with esophageal cancer. Med Hypotheses (2007) 1.40
Controlling silk fibroin particle features for drug delivery. Biomaterials (2010) 1.39
Up-regulation of tumor suppressor genes might promote the malignant phenotype of cancer cells. Med Hypotheses (2007) 1.39
Retracted Stabilization of vaccines and antibiotics in silk and eliminating the cold chain. Proc Natl Acad Sci U S A (2012) 1.39
Nanolayer biomaterial coatings of silk fibroin for controlled release. J Control Release (2007) 1.38
Dengue virus induces expression of CXC chemokine ligand 10/IFN-gamma-inducible protein 10, which competitively inhibits viral binding to cell surface heparan sulfate. J Immunol (2006) 1.38
Molecular depletion of descending serotonin unmasks its novel facilitatory role in the development of persistent pain. J Neurosci (2010) 1.37
Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components. J Biol Chem (2005) 1.37
Retroviruses pseudotyped with the severe acute respiratory syndrome coronavirus spike protein efficiently infect cells expressing angiotensin-converting enzyme 2. J Virol (2004) 1.36
Generation of homogeneous PDX1(+) pancreatic progenitors from human ES cell-derived endoderm cells. J Mol Cell Biol (2009) 1.36
The mammalian exocyst, a complex required for exocytosis, inhibits tubulin polymerization. J Biol Chem (2004) 1.35
Derivation and characterization of hepatic progenitor cells from human embryonic stem cells. PLoS One (2009) 1.33
HIV prevalence and influencing factors analysis of sentinel surveillance among men who have sex with men in China, 2003 - 2011. Chin Med J (Engl) (2012) 1.33
Effect of processing on silk-based biomaterials: reproducibility and biocompatibility. J Biomed Mater Res B Appl Biomater (2011) 1.32
Distribution and contamination assessment of heavy metals in sediment of the Second Songhua River, China. Environ Monit Assess (2007) 1.32
Mouse embryonic head as a site for hematopoietic stem cell development. Cell Stem Cell (2012) 1.31
Exo70p mediates the secretion of specific exocytic vesicles at early stages of the cell cycle for polarized cell growth. J Cell Biol (2007) 1.31
Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice. J Clin Invest (2012) 1.31
[HIV prevalence among populations at risk, using sentinel surveillance data from 1995 to 2009 in China]. Zhonghua Liu Xing Bing Xue Za Zhi (2011) 1.30
Stabilization and release of enzymes from silk films. Macromol Biosci (2010) 1.30
Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors. Oncogene (2005) 1.29
Fiber-based wearable electronics: a review of materials, fabrication, devices, and applications. Adv Mater (2014) 1.29
Stabilization of enzymes in silk films. Biomacromolecules (2009) 1.29
Highly enantioselective hydrophosphonylation of aldehydes catalyzed by tridentate Schiff base aluminum(III) complexes. Angew Chem Int Ed Engl (2008) 1.29
Loci influencing blood pressure identified using a cardiovascular gene-centric array. Hum Mol Genet (2013) 1.27
The role of the exocyst in matrix metalloproteinase secretion and actin dynamics during tumor cell invadopodia formation. Mol Biol Cell (2009) 1.27
The critical role of Exo84p in the organization and polarized localization of the exocyst complex. J Biol Chem (2005) 1.27
Radiation therapy for adrenal gland metastases from hepatocellular carcinoma. Jpn J Clin Oncol (2005) 1.25
Modulation of behavioral phase changes of the migratory locust by the catecholamine metabolic pathway. Proc Natl Acad Sci U S A (2011) 1.24
Mechanisms regulating adipocyte expression of resistin. J Biol Chem (2002) 1.24
The Rho family of small GTPases is involved in epithelial cystogenesis and tubulogenesis. Kidney Int (2003) 1.24