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The human organic cation transporter OCT1 mediates high affinity uptake of the anticancer drug daunorubicin. Sci Rep (2016) 0.78

A novel approach using C. elegans DNA damage-induced apoptosis to characterize the dynamics of uptake transporters for therapeutic drug discoveries. Sci Rep (2016) 0.75

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet. Blood (2009) 15.95

Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure. Yeast (1995) 13.20

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The human ATP-binding cassette (ABC) transporter superfamily. J Lipid Res (2001) 3.95

Genome-wide analysis of gene expression regulated by the calcineurin/Crz1p signaling pathway in Saccharomyces cerevisiae. J Biol Chem (2002) 3.26

Calcineurin signaling in Saccharomyces cerevisiae: how yeast go crazy in response to stress. Biochem Biophys Res Commun (2003) 2.43

Genetic analysis of the multidrug transporter. Annu Rev Genet (1995) 2.29

Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2. J Biol Chem (1998) 2.05

Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus. Pharmacogenomics J (2009) 1.58

Molecular characterization of carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria in Saccharomyces cerevisiae and identification of a plasma membrane carnitine transporter, Agp2p. EMBO J (1999) 1.46

The SLC22 family with transporters of organic cations, anions and zwitterions. Mol Aspects Med (2013) 1.45

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A genome-wide screen in Saccharomyces cerevisiae reveals altered transport as a mechanism of resistance to the anticancer drug bleomycin. Cancer Res (2004) 1.23

Polyamine uptake by DUR3 and SAM3 in Saccharomyces cerevisiae. J Biol Chem (2007) 1.23

Prevalence of multidrug resistance related to activation of the mdr1 gene in human sarcoma mutants derived by single-step doxorubicin selection. Cancer Res (1994) 1.16

Acidic calcium stores of Saccharomyces cerevisiae. Cell Calcium (2011) 1.09

Characterization of the organic cation transporter SLC22A16: a doxorubicin importer. Biochem Biophys Res Commun (2005) 1.08

AGP2 encodes the major permease for high affinity polyamine import in Saccharomyces cerevisiae. J Biol Chem (2005) 1.00

Comparative genome-wide screening identifies a conserved doxorubicin repair network that is diploid specific in Saccharomyces cerevisiae. PLoS One (2009) 1.00

Identification of genes required for protection from doxorubicin by a genome-wide screen in Saccharomyces cerevisiae. Cancer Res (2007) 0.95

Drug resistance mechanisms in acute leukemia. Curr Opin Oncol (2001) 0.90

OCT-1 activity measurement provides a superior imatinib response predictor than screening for single-nucleotide polymorphisms of OCT-1. Leukemia (2010) 0.89

Functional expression of a high affinity mammalian hepatic choline/organic cation transporter. J Lipid Res (2000) 0.88

Drug resistance in hematologic malignancies. Curr Opin Oncol (2001) 0.85

Importance of intracellular pH in determining the uptake and efficacy of the weakly basic chemotherapeutic drug, doxorubicin. PLoS One (2012) 0.85

Anthracycline-dependent cardiotoxicity and extracellular matrix remodeling. Chest (2014) 0.84

Activation of an essential calcium signaling pathway in Saccharomyces cerevisiae by Kch1 and Kch2, putative low-affinity potassium transporters. Eukaryot Cell (2012) 0.84

Agp2, a member of the yeast amino acid permease family, positively regulates polyamine transport at the transcriptional level. PLoS One (2013) 0.83

Knockout of a putative ergothioneine transporter in Caenorhabditis elegans decreases lifespan and increases susceptibility to oxidative damage. Free Radic Res (2013) 0.83

Identity of the F52F12.1 gene product in Caenorhabditis elegans as an organic cation transporter. Biochim Biophys Acta (1999) 0.82

Agp2p, the plasma membrane transregulator of polyamine uptake, regulates the antifungal activities of the plant defensin NaD1 and other cationic peptides. Antimicrob Agents Chemother (2014) 0.80

Functionally redundant protein phosphatase genes PTP2 and MSG5 co-regulate the calcium signaling pathway in Saccharomyces cerevisiae upon exposure to high extracellular calcium concentration. J Biosci Bioeng (2012) 0.78