Published in J Biol Chem on August 07, 1998
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Why we should be vigilant: drug cytotoxicity observed with in vitro transporter inhibition studies. Biochem Pharmacol (2010) 0.83
Cytokine regulation of OCTN2 expression and activity in small and large intestine. Inflamm Bowel Dis (2010) 0.83
A substrate pharmacophore for the human organic cation/carnitine transporter identifies compounds associated with rhabdomyolysis. Mol Pharm (2012) 0.82
Role of solute carriers in response to anticancer drugs. Mol Cell Ther (2014) 0.81
Plasma carnitine ester profile in adult celiac disease patients maintained on long-term gluten free diet. World J Gastroenterol (2005) 0.81
Colon OCTN2 gene expression is up-regulated by peroxisome proliferator-activated receptor gamma in humans and mice and contributes to local and systemic carnitine homeostasis. J Biol Chem (2010) 0.81
Selective regulation of cardiac organic cation transporter novel type 2 (OCTN2) in dilated cardiomyopathy. Am J Pathol (2011) 0.80
Plasma carnitine ester profile in homozygous and heterozygous OCTN2 deficiency. J Inherit Metab Dis (2009) 0.79
Developmental maturation and segmental distribution of rat small intestinal L-carnitine uptake. J Membr Biol (2005) 0.79
Pharmacological characteristics of the specific transporter for the endogenous cell growth inhibitor agmatine in six tumor cell lines. Int J Colorectal Dis (2003) 0.78
Complementation of the Yeast Model System Reveals that Caenorhabditis elegans OCT-1 Is a Functional Transporter of Anthracyclines. PLoS One (2015) 0.78
Drug Transporters and Na+/H+ Exchange Regulatory Factor PSD-95/Drosophila Discs Large/ZO-1 Proteins. Pharmacol Rev (2015) 0.78
Organic cation transporter mRNA and function in the rat superior cervical ganglion. J Physiol (2002) 0.78
The human organic cation transporter OCT1 mediates high affinity uptake of the anticancer drug daunorubicin. Sci Rep (2016) 0.78
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Role of carnitine in cancer chemotherapy-induced multiple organ toxicity. Saudi Pharm J (2010) 0.78
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Inhibition of gene expression of organic cation/carnitine transporter and antioxidant enzymes in oxazaphosphorines-induced acute cardiomyopathic rat models. Oxid Med Cell Longev (2012) 0.77
Identification of functional amino acid residues involved in polyamine and agmatine transport by human organic cation transporter 2. PLoS One (2014) 0.77
Identification of OCTN2 variants and their association with phenotypes of Crohn's disease in a Korean population. Sci Rep (2016) 0.77
Molecular and functional identification of organic anion transporter isoforms in cultured bovine mammary epithelial cells (BME-UV). J Vet Pharmacol Ther (2011) 0.77
Reduced L-carnitine transport in aortic endothelial cells from spontaneously hypertensive rats. PLoS One (2014) 0.77
Carnitine transporter OCTN2 and carnitine uptake in bovine kidney cells is regulated by peroxisome proliferator-activated receptor β/δ. Acta Vet Scand (2014) 0.77
Carnitine transport and fatty acid oxidation. Biochim Biophys Acta (2016) 0.76
Training-induced changes in membrane transport proteins of human skeletal muscle. Eur J Appl Physiol (2006) 0.76
A mutation in SLC22A4 encoding an organic cation transporter expressed in the cochlea strial endothelium causes human recessive non-syndromic hearing loss DFNB60. Hum Genet (2016) 0.76
Effect of L-carnitine supplementation on the body carnitine pool, skeletal muscle energy metabolism and physical performance in male vegetarians. Eur J Nutr (2015) 0.76
Strategies of bacterial over expression of membrane transporters relevant in human health: the successful case of the three members of OCTN subfamily. Mol Biotechnol (2013) 0.76
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Wide tolerance to amino acids substitutions in the OCTN1 ergothioneine transporter. Biochim Biophys Acta (2016) 0.76
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Pharmacological doses of niacin stimulate the expression of genes involved in carnitine uptake and biosynthesis and improve the carnitine status of obese Zucker rats. BMC Pharmacol Toxicol (2014) 0.75
Organic cation transporter 1 (OCT1) is involved in pentamidine transport at the human and mouse blood-brain barrier (BBB). PLoS One (2017) 0.75
Phytochemicals Mediate the Expression and Activity of OCTN2 as Activators of the PPARγ/RXRα Pathway. Front Pharmacol (2016) 0.75
Different involvement of promoter methylation in the expression of organic cation/carnitine transporter 2 (OCTN2) in cancer cell lines. PLoS One (2013) 0.75
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Distribution, molecular structure and functional analysis of carnitine transporter (SLC22A5) in canine lens epithelial cells. Exp Anim (2014) 0.75
Caveolin-1--a novel interacting partner of organic cation/carnitine transporter (Octn2): effect of protein kinase C on this interaction in rat astrocytes. PLoS One (2013) 0.75
Urine L-carnitine excretion in hypertensive adolescents. Ir J Med Sci (2014) 0.75
Urinary Excretion of Tetrodotoxin Modeled in a Porcine Renal Proximal Tubule Epithelial Cell Line, LLC-PK₁. Mar Drugs (2017) 0.75
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Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport. Am J Hum Genet (2017) 0.75
Usefulness of kidney slices for functional analysis of apical reabsorptive transporters. Sci Rep (2017) 0.75
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