Published in Proc Natl Acad Sci U S A on July 27, 2015
An Actin Network Dispatches Ciliary GPCRs into Extracellular Vesicles to Modulate Signaling. Cell (2016) 0.87
Molecular basis for photoreceptor outer segment architecture. Prog Retin Eye Res (2016) 0.87
ARL3 regulates trafficking of prenylated phototransduction proteins to the rod outer segment. Hum Mol Genet (2016) 0.78
Gene Therapeutic Reversal of Peripheral Olfactory Impairment in Bardet-Biedl Syndrome. Mol Ther (2017) 0.75
Protein transport in growing and steady-state cilia. Traffic (2017) 0.75
Whole organism transcriptome analysis of zebrafish models of Bardet-Biedl Syndrome and Alström Syndrome provides mechanistic insight into shared and divergent phenotypes. BMC Genomics (2016) 0.75
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc (2009) 137.99
TANDEM: matching proteins with tandem mass spectra. Bioinformatics (2004) 17.41
Universal sample preparation method for proteome analysis. Nat Methods (2009) 16.88
Open mass spectrometry search algorithm. J Proteome Res (2004) 15.25
XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification. Anal Chem (2006) 15.00
Intraflagellar transport. Nat Rev Mol Cell Biol (2002) 10.86
A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. Cell (2007) 10.75
Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips. Nat Protoc (2007) 10.71
The renewal of photoreceptor cell outer segments. J Cell Biol (1967) 5.81
A cross-platform toolkit for mass spectrometry and proteomics. Nat Biotechnol (2012) 4.48
The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes. Invest Ophthalmol Vis Sci (2012) 4.11
Intraflagellar transport (IFT) role in ciliary assembly, resorption and signalling. Curr Top Dev Biol (2008) 4.10
The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia. Cell (2010) 3.83
Functional coordination of intraflagellar transport motors. Nature (2005) 3.43
Trafficking to the ciliary membrane: how to get across the periciliary diffusion barrier? Annu Rev Cell Dev Biol (2010) 3.38
General framework for developing and evaluating database scoring algorithms using the TANDEM search engine. Bioinformatics (2006) 3.35
Loss of C. elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport. Genes Dev (2004) 3.21
A BBSome subunit links ciliogenesis, microtubule stability, and acetylation. Dev Cell (2008) 3.17
Bbs2-null mice have neurosensory deficits, a defect in social dominance, and retinopathy associated with mislocalization of rhodopsin. Proc Natl Acad Sci U S A (2004) 3.11
Massive light-driven translocation of transducin between the two major compartments of rod cells: a novel mechanism of light adaptation. Neuron (2002) 3.09
Rod outer segment disk shedding in rat retina: relationship to cyclic lighting. Science (1976) 3.04
Bardet-Biedl syndrome type 4 (BBS4)-null mice implicate Bbs4 in flagella formation but not global cilia assembly. Proc Natl Acad Sci U S A (2004) 3.01
The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella. J Cell Biol (2009) 2.55
Light-driven translocation of signaling proteins in vertebrate photoreceptors. Trends Cell Biol (2006) 2.36
A knockin mouse model of the Bardet-Biedl syndrome 1 M390R mutation has cilia defects, ventriculomegaly, retinopathy, and obesity. Proc Natl Acad Sci U S A (2007) 2.36
Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice. J Clin Invest (2008) 2.24
The membrane fusion enigma: SNAREs, Sec1/Munc18 proteins, and their accomplices--guilty as charged? Annu Rev Cell Dev Biol (2012) 2.19
Mkks-null mice have a phenotype resembling Bardet-Biedl syndrome. Hum Mol Genet (2005) 2.04
SARA-regulated vesicular targeting underlies formation of the light-sensing organelle in mammalian rods. Cell (2007) 1.91
A frameshift mutation in prominin (mouse)-like 1 causes human retinal degeneration. Hum Mol Genet (2000) 1.87
Photoreceptor signaling: supporting vision across a wide range of light intensities. J Biol Chem (2011) 1.62
X!!Tandem, an improved method for running X!tandem in parallel on collections of commodity computers. J Proteome Res (2007) 1.55
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened. PLoS Genet (2011) 1.49
Loss of Bardet-Biedl syndrome proteins alters the morphology and function of motile cilia in airway epithelia. Proc Natl Acad Sci U S A (2008) 1.49
Dopamine receptor 1 localizes to neuronal cilia in a dynamic process that requires the Bardet-Biedl syndrome proteins. Cell Mol Life Sci (2010) 1.45
Three-dimensional architecture of the rod sensory cilium and its disruption in retinal neurodegeneration. Cell (2012) 1.40
IFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment. Dev Cell (2014) 1.40
Syntaxin 3 and SNAP-25 pairing, regulated by omega-3 docosahexaenoic acid, controls the delivery of rhodopsin for the biogenesis of cilia-derived sensory organelles, the rod outer segments. J Cell Sci (2009) 1.39
Loss of the cholesterol-binding protein prominin-1/CD133 causes disk dysmorphogenesis and photoreceptor degeneration. J Neurosci (2009) 1.39
Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes. Proc Natl Acad Sci U S A (2011) 1.32
The outer segment serves as a default destination for the trafficking of membrane proteins in photoreceptors. J Cell Biol (2008) 1.32
Exome sequencing identifies mutations in LZTFL1, a BBSome and smoothened trafficking regulator, in a family with Bardet--Biedl syndrome with situs inversus and insertional polydactyly. J Med Genet (2012) 1.30
Retinal dystrophy in Bardet-Biedl syndrome and related syndromic ciliopathies. Prog Retin Eye Res (2011) 1.28
Application of acrylamide as an embedding medium in studies of lectin and antibody binding in the vertebrate retina. Curr Eye Res (1984) 1.26
Neuropeptide Y family receptors traffic via the Bardet-Biedl syndrome pathway to signal in neuronal primary cilia. Cell Rep (2013) 1.19
The Arf GAP ASAP1 provides a platform to regulate Arf4- and Rab11-Rab8-mediated ciliary receptor targeting. EMBO J (2012) 1.18
Molecular complexes that direct rhodopsin transport to primary cilia. Prog Retin Eye Res (2013) 1.16
Cycling of the signaling protein phospholipase D through cilia requires the BBSome only for the export phase. J Cell Biol (2013) 1.16
Transport to the photoreceptor outer segment by myosin VIIa and kinesin II. Vision Res (2002) 1.14
Protein sorting, targeting and trafficking in photoreceptor cells. Prog Retin Eye Res (2013) 1.13
MassSieve: panning MS/MS peptide data for proteins. Proteomics (2010) 1.02
Subretinal gene therapy of mice with Bardet-Biedl syndrome type 1. Invest Ophthalmol Vis Sci (2013) 1.01
Retrograde intraflagellar transport by cytoplasmic dynein-2 is required for outer segment extension in vertebrate photoreceptors but not arrestin translocation. Invest Ophthalmol Vis Sci (2009) 0.98
Adaptive changes in visual cell transduction protein levels: effect of light. Exp Eye Res (1991) 0.90
Mesoaxial polydactyly is a major feature in Bardet-Biedl syndrome patients with LZTFL1 (BBS17) mutations. Clin Genet (2013) 0.79