Published in Sci Rep on August 04, 2015
Global DNA methylation patterns in Barrett's esophagus, dysplastic Barrett's, and esophageal adenocarcinoma are associated with BMI, gender, and tobacco use. Clin Epigenetics (2016) 1.39
Methylation of S100A8 is a promising diagnosis and prognostic marker in hepatocellular carcinoma. Oncotarget (2016) 0.81
Ranking, selecting, and prioritising genes with desirability functions. PeerJ (2015) 0.75
Comprehensive molecular portraits of human breast tumours. Nature (2012) 47.39
Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes. Genome Res (2005) 44.08
DNA methylation patterns and epigenetic memory. Genes Dev (2002) 33.83
Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature (2008) 30.29
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet (2007) 20.22
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet (2009) 18.90
DNA methylation profiling of human chromosomes 6, 20 and 22. Nat Genet (2006) 18.08
Eukaryotic cytosine methyltransferases. Annu Rev Biochem (2005) 15.45
Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat Rev Genet (2012) 15.21
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature (2000) 14.91
DNA methylation and human disease. Nat Rev Genet (2005) 12.00
Linking colorectal cancer to Wnt signaling. Cell (2000) 11.58
Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells. Nat Biotechnol (2009) 11.18
The role of DNA methylation in mammalian epigenetics. Science (2001) 9.26
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat Med (1995) 9.10
DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science (2003) 8.81
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat Genet (2004) 7.78
Conservation and divergence of methylation patterning in plants and animals. Proc Natl Acad Sci U S A (2010) 7.30
CpG island methylator phenotype in cancer. Nat Rev Cancer (2004) 7.13
Association of BRCA1 and BRCA2 mutations with survival, chemotherapy sensitivity, and gene mutator phenotype in patients with ovarian cancer. JAMA (2011) 6.81
CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2. Proc Natl Acad Sci U S A (2006) 5.95
Charting a dynamic DNA methylation landscape of the human genome. Nature (2013) 5.80
Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops. Nat Genet (2004) 5.47
Insulators and boundaries: versatile regulatory elements in the eukaryotic genome. Science (2001) 5.37
Enhancer function: new insights into the regulation of tissue-specific gene expression. Nat Rev Genet (2011) 5.27
Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12. Nat Genet (2003) 4.25
Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population. PLoS Genet (2012) 4.05
Analysing and interpreting DNA methylation data. Nat Rev Genet (2012) 3.77
Dynamic DNA methylation across diverse human cell lines and tissues. Genome Res (2013) 3.61
Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification. Cancer Res (1999) 3.48
Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study. Gastroenterology (2007) 3.39
Interplay between the cancer genome and epigenome. Cell (2013) 3.05
Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia. Cancer Cell (2011) 2.89
Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity. Genome Res (2009) 2.87
Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach. Cancer Cell (2004) 2.73
Differentially regulated micro-RNAs and actively translated messenger RNA transcripts by tumor suppressor p53 in colon cancer. Clin Cancer Res (2006) 2.72
Multiple imprinted sense and antisense transcripts, differential methylation and tandem repeats in a putative imprinting control region upstream of mouse Igf2. Proc Natl Acad Sci U S A (1997) 2.52
Whole-genome DNA methylation profiling using MethylCap-seq. Methods (2010) 2.29
Gene body methylation can alter gene expression and is a therapeutic target in cancer. Cancer Cell (2014) 2.28
Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer. BMC Cancer (2009) 2.27
ChAMP: 450k Chip Analysis Methylation Pipeline. Bioinformatics (2013) 2.21
Immune system and prognosis in colorectal cancer: a detailed immunohistochemical analysis. Lab Invest (2004) 2.05
A genome-wide study of DNA methylation patterns and gene expression levels in multiple human and chimpanzee tissues. PLoS Genet (2011) 1.92
An intragenic methylated region in the imprinted Igf2 gene augments transcription. EMBO Rep (2001) 1.63
Epigenetic inactivation of the HOXA gene cluster in breast cancer. Cancer Res (2006) 1.63
Robust rank aggregation for gene list integration and meta-analysis. Bioinformatics (2012) 1.60
From the cradle to the grave: activities of GATA-3 throughout T-cell development and differentiation. Immunol Rev (2010) 1.60
Wnt breakers in colon cancer. Cancer Cell (2004) 1.46
Supervised enzyme network inference from the integration of genomic data and chemical information. Bioinformatics (2005) 1.28
GAT: a simulation framework for testing the association of genomic intervals. Bioinformatics (2013) 1.27
Promoter hypomethylation regulates CD133 expression in human gliomas. Cell Res (2008) 1.27
Long non-coding RNAs in the regulation of the immune response. Trends Immunol (2014) 1.24
An upstream repressor element plays a role in Igf2 imprinting. EMBO J (2001) 1.22
DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation. Cancer Res (2008) 1.17
Expression of oligodendroglial and astrocytic lineage markers in diffuse gliomas: use of YKL-40, ApoE, ASCL1, and NKX2-2. J Neuropathol Exp Neurol (2006) 1.10
Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues. Epigenetics (2012) 1.08
Immune markers and differential signaling networks in ulcerative colitis and Crohn's disease. Inflamm Bowel Dis (2012) 1.07
FOXC2 is a novel prognostic factor in human esophageal squamous cell carcinoma. Ann Surg Oncol (2010) 1.06
Conservation and divergence in eukaryotic DNA methylation. Proc Natl Acad Sci U S A (2010) 1.02
NKX2.2 is a useful immunohistochemical marker for Ewing sarcoma. Am J Surg Pathol (2012) 0.98
Cancer cells cut homophilic cell adhesion molecules and run. Cancer Res (2010) 0.96
Probe Lasso: a novel method to rope in differentially methylated regions with 450K DNA methylation data. Methods (2014) 0.92
Prioritizing cancer-related key miRNA-target interactions by integrative genomics. Nucleic Acids Res (2012) 0.86
Functional DNA methylation in a transcript specific 3'UTR region of TrkB associates with suicide. Epigenetics (2014) 0.86
Gene expression of mesenchyme forkhead 1 (FOXC2) significantly correlates with the degree of lymph node metastasis in colorectal cancer. Int Surg (2012) 0.85
CAHM, a long non-coding RNA gene hypermethylated in colorectal neoplasia. Epigenetics (2014) 0.83
Integrating epigenetic marks for identification of transcriptionally active miRNAs. Genomics (2014) 0.79
Fibrillin-2, tenascin-C, matrilin-2, and matrilin-4 are strongly expressed in the epithelium of human granular and lattice type I corneal dystrophies. Mol Vis (2012) 0.77
Predicting the functions of long noncoding RNAs using RNA-seq based on Bayesian network. Biomed Res Int (2015) 0.80
Identifying core gene modules in glioblastoma based on multilayer factor-mediated dysfunctional regulatory networks through integrating multi-dimensional genomic data. Nucleic Acids Res (2015) 0.79
Computational identification of epigenetically regulated lncRNAs and their associated genes based on integrating genomic data. FEBS Lett (2015) 0.76
A functional module-based exploration between inflammation and cancer in esophagus. Sci Rep (2015) 0.75
Gene Perturbation Atlas (GPA): a single-gene perturbation repository for characterizing functional mechanisms of coding and non-coding genes. Sci Rep (2015) 0.75