Association of DNA Repair Gene APE1 Asp148Glu Polymorphism with Breast Cancer Risk.

PubWeight™: 0.78‹?›

🔗 View Article (PMC 4519542)

Published in Dis Markers on July 16, 2015

Authors

Fatima AlMutairi1, Akbar Ali Khan Pathan2, Mohammed Alanazi1, Manal Shalaby3, Huda A Alabdulkarim4, Abdullah Alamri1, Abdulrahman Al Naeem5, Moammad Elrobh1, Jilani P Shaik1, Wajahatullah Khan6, Zahid Khan1, Narasimha Reddy Parine1

Author Affiliations

1: Genome Research Chair, Department of Biochemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
2: Genome Research Chair, Department of Biochemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia ; Integrated Gulf Biosystems, Riyadh 11391, Saudi Arabia.
3: Genome Research Chair, Department of Biochemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia ; Genetic Engineering and Biotechnology Research Institute (GEBRI), City for Scientific Research and Technology Applications, Alexandria 21934, Egypt.
4: The Comprehensive Cancer Center, King Fahad Medical City, Riyadh 11525, Saudi Arabia.
5: Department of Women's Imaging, King Fahad Medical City, Riyadh 11525, Saudi Arabia.
6: Department of Basic Sciences, College of Science and Health Professions, King Saud Bin Abdul Aziz University for Health Sciences, Riyadh 11426, Saudi Arabia.

Articles cited by this

CHARMM: the biomolecular simulation program. J Comput Chem (2009) 27.71

I-TASSER: a unified platform for automated protein structure and function prediction. Nat Protoc (2010) 22.66

Allelic discrimination using fluorogenic probes and the 5' nuclease assay. Genet Anal (1999) 9.80

ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins. Nucleic Acids Res (2007) 9.16

Repair of oxidative damage to DNA: enzymology and biology. Annu Rev Biochem (1994) 7.80

Evaluation of comparative protein modeling by MODELLER. Proteins (1995) 6.42

Human DNA repair genes. Science (2001) 6.11

Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme. EMBO J (1992) 5.23

Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300. EMBO J (1999) 3.70

The enzymology of apurinic/apyrimidinic endonucleases. Mutat Res (1990) 3.21

Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfaces. BMC Bioinformatics (2010) 2.85

The many functions of APE1/Ref-1: not only a DNA repair enzyme. Antioxid Redox Signal (2009) 2.43

CUPSAT: prediction of protein stability upon point mutations. Nucleic Acids Res (2006) 2.38

Consanguinity among the Saudi Arabian population. J Med Genet (1995) 2.30

Structure and function of apurinic/apyrimidinic endonucleases. Bioessays (1995) 1.98

Transcriptional regulatory functions of mammalian AP-endonuclease (APE1/Ref-1), an essential multifunctional protein. Antioxid Redox Signal (2009) 1.81

Mammalian base excision repair: the forgotten archangel. Nucleic Acids Res (2013) 1.79

PoPMuSiC 2.1: a web server for the estimation of protein stability changes upon mutation and sequence optimality. BMC Bioinformatics (2011) 1.76

Ref-1 regulates the transactivation and pro-apoptotic functions of p53 in vivo. EMBO J (1999) 1.59

Effects of estrogen receptor expression and histopathology on annual hazard rates of death from breast cancer. Breast Cancer Res Treat (2006) 1.58

Challenges and complexities in estimating both the functional impact and the disease risk associated with the extensive genetic variation in human DNA repair genes. Mutat Res (2003) 1.53

Choreography of oxidative damage repair in mammalian genomes. Free Radic Biol Med (2002) 1.43

Requirement for human AP endonuclease 1 for repair of 3'-blocking damage at DNA single-strand breaks induced by reactive oxygen species. Carcinogenesis (2000) 1.40

Enzymology of the repair of free radicals-induced DNA damage. Oncogene (2002) 1.29

Base excision repair and its role in maintaining genome stability. Crit Rev Biochem Mol Biol (2008) 1.21

Contribution of base excision repair, nucleotide excision repair, and DNA recombination to alkylation resistance of the fission yeast Schizosaccharomyces pombe. J Bacteriol (2000) 1.19

Subcellular localization of APE1/Ref-1 in human hepatocellular carcinoma: possible prognostic significance. Mol Med (2007) 1.17

Possible associations of APE1 polymorphism with susceptibility and HOGG1 polymorphism with prognosis in gastric cancer. Anticancer Res (2010) 1.14

Polymorphisms in three base excision repair genes and breast cancer risk in Thai women. Breast Cancer Res Treat (2007) 1.09

Association between polymorphisms in the DNA repair genes XRCC1 and APE1, and the risk of prostate cancer in white and black Americans. J Urol (2006) 1.09

Base excision repair pathway genes polymorphism in prostate and bladder cancer risk in North Indian population. Mech Ageing Dev (2011) 1.03

Association between PARP-1 V762A polymorphism and breast cancer susceptibility in Saudi population. PLoS One (2013) 1.03

Human apurinic/apyrimidinic endonuclease (APE1) is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancers. Br J Cancer (2010) 1.02

Ref-1 controls pax-8 DNA-binding activity. Biochem Biophys Res Commun (1998) 1.01

Genetic polymorphism of DNA base-excision repair genes (APE1, OGG1 and XRCC1) and their correlation with risk of lung cancer in a Chinese population. Arch Med Res (2011) 0.98

APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions. Exp Mol Med (2014) 0.97

Association of single nucleotide polymorphisms in Wnt signaling pathway genes with breast cancer in Saudi patients. PLoS One (2013) 0.95

DNA base-excision repair enzyme apurinic/apyrimidinic endonuclease/redox factor-1 is increased and competent in the brain and spinal cord of individuals with amyotrophic lateral sclerosis. Neuromolecular Med (2002) 0.92

Polymorphisms of the DNA polymerase beta gene in breast cancer. Breast Cancer Res Treat (2006) 0.88

Common polymorphisms and somatic mutations in human base excision repair genes in ovarian and endometrial cancers. Mutat Res (2001) 0.87

NMR studies reveal an unexpected binding site for a redox inhibitor of AP endonuclease 1. Biochemistry (2011) 0.86

DNA Repair Genes XRCC1, XRCC3, XPD, and OGG1 Polymorphisms among the Central Region Population of Saudi Arabia. Biol Res (2013) 0.86

APE1 Asp148Glu gene polymorphism and bladder cancer risk: a meta-analysis. Mol Biol Rep (2012) 0.79

The association between the APE1 Asp148Glu polymorphism and breast cancer susceptibility: a meta-analysis based on case-control studies. Tumour Biol (2014) 0.77

Novel hypoxanthine guanine phosphoribosyltransferase gene mutations in Saudi Arabian hyperuricemia patients. Biomed Res Int (2014) 0.77